1. Cancer-Related Therapeutic Potential of <italic>Epimedium</italic> and Its Extracts.
- Author
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Ding, Jipeng, Li, Changcheng, Wang, Guanzheng, Yang, Yiming, and Li, Jing
- Subjects
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HERBS , *MATERIA medica , *ANTINEOPLASTIC agents , *EXTRACTION techniques , *CARDIOVASCULAR system , *BIOACTIVE compounds - Abstract
Abstract
Epimedium is a Chinese herb known as “yin and yang fire,” first mentioned in the Compendium of Materia Medica. Many of the proprietary Chinese medicines used in clinical practice containEpimedium as an ingredient, and its main active constituents include icariin, icaritin, and icariside II, among others. In addition to its traditional use in treating fatigue and sexual problems, modern research has confirmed that the main bioactive compounds inEpimedium have pharmacological effects such as antidepressant, antibacterial, antiviral, antioxidant, and anti-inflammatory properties, as well as inhibiting bone destruction, promoting bone growth, improving immune regulation and protecting the cardio-cerebral vascular system. With the continuous development of extraction and purification techniques, the development and use of bioactive compounds inEpimedium have significantly progressed, and the anticancer effect has received widespread attention. Since natural herbs have few side effects on the human body and do not easily develop drug resistance, they have long been the direction of research in cancer treatment. This review summarizes the latest research on the anticancer effects ofEpimedium and its extracts, describes the bioactive compounds, pharmacological efficacy, and antitumor mechanism ofEpimedium , and gives a new view on the administration and development ofEpimedium . [ABSTRACT FROM AUTHOR]- Published
- 2024
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