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468 results on '"Gage, Fred H."'

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1. A framework for neural organoids, assembloids and transplantation studies.

2. miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis.

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3. Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission.

4. Adult Neurogenesis in the Human Dentate Gyrus.

5. Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.

6. Modeling Alzheimer's disease using human cell derived brain organoids and 3D models.

7. Neuronal senescence may drive brain aging.

8. Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.

9. Protocol for the San Diego Nathan Shock Center Clinical Cohort: a new resource for studies of human aging.

10. High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer.

11. Upregulated ECM genes and increased synaptic activity in Parkinson's human DA neurons with PINK1/ PRKN mutations.

12. Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures.

13. Lifelong persistence of nuclear RNAs in the mouse brain.

14. Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain.

15. Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation.

16. Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson's disease patients.

17. Tyro3 promotes the maturation of glutamatergic synapses.

18. Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis.

19. NGLY1 mutations cause protein aggregation in human neurons.

20. Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases.

21. Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients.

22. Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.

23. Neural cell state shifts and fate loss in ageing and age-related diseases.

24. An in vivo neuroimmune organoid model to study human microglia phenotypes.

25. Novel correlative analysis identifies multiple genomic variations impacting ASD with macrocephaly.

28. Transplantation Strategies to Enhance Maturity and Cellular Complexity in Brain Organoids.

29. Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells.

30. BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT P301S mouse model of tauopathy.

31. Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex.

32. Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease.

33. Human-specific regulation of neural maturation identified by cross-primate transcriptomics.

34. Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons.

35. Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease.

36. A nomenclature consensus for nervous system organoids and assembloids.

37. Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson's disease patients.

38. Methods for culturing adult CNS neurons reveal a CNS conditioning effect.

39. Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Psychiatric Disorders.

41. Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients.

43. Intermittent fasting enhances long-term memory consolidation, adult hippocampal neurogenesis, and expression of longevity gene Klotho.

44. The San Diego Nathan Shock Center: tackling the heterogeneity of aging.

45. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients.

46. The role of retrotransposable elements in ageing and age-associated diseases.

47. AAV ablates neurogenesis in the adult murine hippocampus.

48. Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis.

49. Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes.

50. Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies.