1. Thalamic Visual Prosthesis
- Author
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Faris Tarlochan, W. Jong Yoon, Siva Mahesh Tangutooru, John B. Troy, Andrew J. Kantzos Kantzos, Corey M. Rountree, and Hieu T. Nguyen
- Subjects
genetic structures ,muscle ,Visual system ,Retinal ganglion cells ,0302 clinical medicine ,Thalamus ,visual prosthesis ,visual cortex ,Visual pathways ,pathophysiology ,Prosthetics ,neurocysticercosis ,Geniculate Bodies ,electrostimulation ,electrical method ,eye ,Lateral geniculate nucleus ,Visual Prosthesis ,medicine.anatomical_structure ,Visual cortexes ,Psychology ,blindness ,vision ,brain ,Biomedical Engineering ,Vision restoration therapy ,Retinal ganglion ,Electrical stimulations ,Article ,thalamic visual prosthesis ,03 medical and health sciences ,Neural prostheses ,medicine ,Humans ,human ,Vision, Ocular ,Retina ,Aldehydes ,nonhuman ,surgical approach ,nerve cell necrosis ,prosthesis design ,abnormality ,Glaucoma ,nerve cell plasticity ,lateral geniculate body ,nerve cell stimulation ,eye diseases ,Electric Stimulation ,Ophthalmology ,Visual cortex ,nervous system ,Visual prosthesis ,physiology ,030221 ophthalmology & optometry ,sense organs ,geniculate body ,numerical model ,Neuroscience ,030217 neurology & neurosurgery ,Neurological disorders - Abstract
Glaucoma is a neurological disorder leading to blindness initially through the loss of retinal ganglion cells, followed by loss of neurons higher in the visual system. Some work has been undertaken to develop prostheses for glaucoma patients targeting tissues along the visual pathway, including the lateral geniculate nucleus (LGN) of the thalamus, but especially the visual cortex. This review makes the case for a visual prosthesis that targets the LGN. The compact nature and orderly structure of this nucleus make it a potentially better target to restore vision than the visual cortex. Existing research for the development of a thalamic visual prosthesis will be discussed along with the gaps that need to be addressed before such a technology could be applied clinically, as well as the challenge posed by the loss of LGN neurons as glaucoma progresses. 1964-2012 IEEE. Scopus
- Published
- 2016