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Worldwide cancer death among women is caused secondly by Breast cancer. The emergence of resistance to multi therapeutics among breast cancer patients is a serious issue to be addressed immediately and global initiatives are in the focus by WHO to reduce the mortality rate. In this stance, targeted drug therapy is scaling the heights to combat the therapeutic resistance. Recent studies conclusively underscored Cyclin-dependent kinase 8 (CDK8) as a critical drug target for breast cancer and associated metastasis. Here in, different categories of phytomolecules namely, Amentoflavone, Oxymatrine, Punicic acid, Punicic acid and trans-Resvertrol were screened against the protein 5CEI by structure based molecular docking and ADME prediction. A bench mark had made with comparative evaluation of identical studies on the anti Breast cancer drug Anastrazole and the phytomolecule Curcumin which was well known for its anti cancer activity. The results showed highest docking score of -7.9 for Amentoflavone with the target protein. Except for Punicic acid the binding energy values obtained were lower than Curcumin. Upon evaluation of the molecular properties, it is inferred that even when Amentaflavone violates the Lipinski's rule it is showing considerable stability of docking with the active site of therapeutic target selected for the present study leading to the inhibition of the activity. The advantage of Amentoflavone, is that it is a nontoxic dietary supplement. The results of the study points to the futuristic aspect of further r investigations of the pharmacological properties in order to ascertain leads in the management of Breast Cancer. [ABSTRACT FROM AUTHOR]

The study of photoproduction of mesons plays an important role in understanding the properties of strong interactions. Pion photoproduction on deuterons has been studied theoretically for several decades. At the VEPP − 3 storage rings, tensor analysing powers in γ + d → d + π0 have recently been measured. In light of these advances, we suggest adopting an irreducible tensor technique to explore the reaction γ + d → d + π0 at close to threshold energies. Our method, which is model-independent, works well for predictions regarding spin observables. By describing the differential cross section in terms of multipole amplitudes, the angular dependence of the cross section will be studied. [ABSTRACT FROM AUTHOR]

The study of photoproduction of mesons plays an important role in understanding the properties of strong interactions. Pion photoproduction on deuterons has been studied theoretically for several decades. At the VEPP − 3 storage rings, tensor analysing powers in γ + d → d + π0 have recently been measured. In light of these advances, we suggest adopting an irreducible tensor technique to explore the reaction γ + d → d + π0 at close to threshold energies. Our method, which is model-independent, works well for predictions regarding spin observables. By describing the differential cross section in terms of multipole amplitudes, the angular dependence of the cross section will be studied. [ABSTRACT FROM AUTHOR]

During this pandemic time, hospitals and patients are facing lack of shortage of medical infrastructure. Doctors are panic about patient health. So, we invented a small ventilator device. It is an easy-to-use, low-cost, highly flexible, and open-source ventilator. It can measure temperature, blood pressure, respiratory rate, etc. This kind of ventilator is beneficial in pandemic times. It can be controlled using microcontroller devices. Here we used Raspberry pi, and it is the central part of the project. Results can be maintained and monitored. Results show the data of the patient's condition, whether he is normal or abnormal. Results are shown in LCD. And the data is stored in the cloud using the webserver. When the patient's condition is uncommon, devices give an intimation. A doctor can check the condition of patients at anytime and anywhere. These devices are handy to doctors and patients at an emergency time and covid-19 times. Insufficient medical infrastructure causes painful deaths in the world. We invented our project to help the patient in emergency times at a low cost. For the sake of Patients' health, we developed this project at a low price. [ABSTRACT FROM AUTHOR]

This paper presents a metamaterial Split Ring Resonator (SRR) based sensor for monitoring the compaction profile of food powders which may find applications in efficient transportation of powder products by optimizing the packing space. This method makes use of the resonant properties of the negative permeability structural part of metamaterials-SRR, one of the prominent sensor probes recently developing in the state-of-the art. By analyzing the change in the resonance behavior occurred due to the variations in the dielectric permittivity of food samples in the near- field region of the sensor probe, the packing density of selected food powder are deduced. Four food powder samples are selected for the study, out of which two are free flowing and other two are non–free flowing where the flowability is determined based on the standard Angle of Repose (AOR) measurement. Powder samples of different compaction rate are arranged in the near-field region of the SRR test probe which is set between the receiving and transmitting probes connected to a Vector Network Analyzer (VNA) constitute the experimental setup. Noticeable variation in resonant frequency is observed which hints at the possibility of packing in an efficient manner using this non-destructive, low cost and reliable metamaterial based sensing method. [ABSTRACT FROM AUTHOR]

The magnetic and electric properties of Ni- BaTiO3- Polydimethylsiloxane (PDMS) composite has been investigated. Any system with spin-charge coupling at room temperature is expected to be useful for device applications. Nickel is a room temperature ferromagnet, and barium titanate is a room temperature ferroelectric material, which makes the system as a magnetoelectric. The polymer PDMS was used to make the flexible magnetoelectric material. It is observed that the saturation magnetization is reduced by the presence of polymer, and coercivity is not much lowered. Also, the effect of filler loading on the magnetic and electric properties is studied. [ABSTRACT FROM AUTHOR]

Variable range hopping (VRH) of polarons constitutes the conduction mechanism in monoclinic Pr2CoMnO6 perovskite. Thermomagnetic data suggests ferromagnetic interactions are prominent and ferromagnetic to the paramagnetic transition of the compound is found to be at 178 K. M-H loops at different temperatures characterizes the exact magnetic behavior of the perovskite. [ABSTRACT FROM AUTHOR]

The C1.25Fe1.75O4 ferrite was prepared by chemical co-precipitation and post annealing at 900°C. The nuclear structure (lattice) and magnetic structure were determined by analyzing the Neutron diffraction patterns. The A and B sublattice magnetic moments confirmed ferrimagnetic order in cubic spinel structure. The net moment is comparable to data from dc magnetic measurement. The system exhibited an anomaly below 100 K, where increase of lattice parameter on decreasing the temperature (negative lattice expansion) is accompanying with the decrease of magnetization curve. [ABSTRACT FROM AUTHOR]

The perovskite La2FeReO6 is prepared by solid-state reaction method. Calcination was done in a controlled reducing atmosphere. The structure of the compound is found to be orthorhombic with Pbnm space group. From the DC magnetic studies, the transition temperature (TC) of La2FeReO6 is found to be at 729 K. A Griffiths-like phase is present in the material with ferromagnetic short-range correlations above TC up to the Griffiths temperature TG = 863 K. [ABSTRACT FROM AUTHOR]

Magnetometers are sensors used in magnetic field detection, which are often used in oceanographic, industrial and biomedical field. Present work deals with the design and analysis of dual axis MEMS Magnetometer based on Lorentz force principle, with a sensing range of 1uT to 1001uT. Designing of MEMS Magnetometer is carried out using COMSOL Multiphysics 5.0. FEM analysis including model analysis, FEM Thermomechanical analysis, Frequency analysis for finding displacement sensitivity are carried out. [ABSTRACT FROM AUTHOR]

The Co2.75Fe0.25O4 ferrite has been prepared by chemical co-precipitation route. The as-prepared sample has been annealed at 500° C. X-ray diffraction pattern indicated cubic spinel structure in the sample. The sample showed ferrimagnetic nature with magnetic irreversibility and hysteresis loop. Magnetization data revealed high anisotropic nature and at least two prominent meta-stable magnetic transitions below the highest measurement temperature 350 K. [ABSTRACT FROM AUTHOR]