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[Display omitted] • Correlated Acer truncatum leaf (ATL) metabolites and environmental factors. • Flavonoids (FLAs) and gallic acid-containing products (GANPs) are main metabolites. • Thirty-four compounds were identified for the first time from A. truncatum. • FLAs and GANPs levels are affected by humidity, temperature, and sunshine duration. • Prioritized cultivation sites for harvesting ATL with potential health benefits. Traditionally in Northern China, Acer truncatum leaves (ATL) have been used as herbal tea, now consumed worldwide. Few studies have reported ATL metabolites from different areas and their correlation with the environment. Thus, metabolomic analyses were conducted on ATL collected from twelve locations throughout four environmental zones in Northern China to understand the phytochemical differences with regards to environmental conditions. Sixty-four compounds, mostly flavonoids (FLAs) and gallic acid-containing natural products (GANPs), were characterized, including 34 previously unreported constituents from A. truncatum. Twenty-two markers were useful to differentiate ATL from the four environmental zones. Humidity, temperature, and sunshine duration are the predominant factors affecting FLAs and GANPs levels. Sunshine duration was positively correlated with eriodictyol (r = 0.994, p < 0.01), and humidity negatively with epicatechin gallate (r = −0.960, p < 0.05). These findings provide insights into ATL phytochemistry, aiding cultivation of A. truncatum tea with higher potential health benefits. [ABSTRACT FROM AUTHOR]

Highlights: [•] Prohexadione-calcium treatment alters flavour compound biosynthesis in hops. [•] Twenty-nine metabolites among three pathways were targeted by LC-ToF-MS and UHPLC methods. [•] Developmental time-courses revealed changes in the velocity of accumulation of hop bitter acids. [•] Prohexadione-calcium may be useful for crop and food quality improvement. [ABSTRACT FROM AUTHOR]

Abstract: Bioassay-guided fractionation of the methanolic extracts of the pulp and seeds of the fruits of Syzygium samarangense (Blume) Merr. and L.M. Perry led to the identification of four cytotoxic compounds and eight antioxidants on the basis of HPLC-PDA analysis, MS, and various NMR spectroscopic techniques. Three C-methylated chalcones, 2′,4′-dihydroxy-3′,5′-dimethyl-6′-methoxychalcone (1), 2′,4′-dihydroxy-3′-methyl-6′-methoxychalcone (stercurensin, 2), and 2′,4′-dihydroxy-6′-methoxychalcone (cardamonin, 3), were isolated and displayed cytotoxic activity (IC50 =10, 35, and 35μM, respectively) against the SW-480 human colon cancer cell line. Also a number of known antioxidants were obtained including six quercetin glycosides: reynoutrin (4), hyperin (5), myricitrin (6), quercitrin (7), quercetin (9), and guaijaverin (10), one flavanone: (S)-pinocembrin (8), and two phenolic acids: gallic acid (11) and ellagic acid (12). [Copyright &y& Elsevier]