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Objective To observe the clinical efficacy of arthroscopic minimally invasive surgery combined with sodium silicate and warm acupuncture in the treatment of knee osteoarthritis (KOA). Methods A total of 73 KOA patients who met the inclusion criteria from June 2015 to June 2017 were enrolled in the study. They were randomly divided into the treatment group (n = 39) and the control group (n = 34 ) . The control group was treated with intra articular injection of sodium hyaluronate and warm acupuncture. In addition to the above treatment, the treatment group assisted arthroscopy. The visual analogue scale ( VAS score) and the Lysholm knee function score were compared between the two groups. By comparing the levels of serum transforming growth factor β (TGF β) and insulin like growth factor 1 (IGF 1) before and after treatment, the clinical effects of the two groups before and after treatment were studied. Results Compared with before treatment, the VAS scores of the two groups were followed up at 1, 3, 6 and 12 months after treatment, and the differences were statistically significant ( P < 0.05 ) . The Lysholm knee fuction scores in both groups showed an upward trend, and the scores of the treatment group were better than that in the control group, and the differences were statistically significant ( P < 0 05). The serum levels of TGF β and IGF 1 were higher in the two groups than in the control group, and the differences were statistically significant ( P < 0.05). Conclusion Arthroscopic debridement combined with sodium hyaluronate and warm acupuncture for the treatment of knee osteoarthritis can significantly relieve symptoms, improve joint function, and is associated with elevated serum levels of TGF β and IGF 1. [ABSTRACT FROM AUTHOR]

Objective To explore the influence of Wuhuang decoction lavage on the expression of IT-8 and intercellular cell adhesion molecule-1 (ICAM-1) in sinus secretions of fungal rhinosinusitis (FRS) after operation. Methods A randomized controlled trial was used ,60 FRS patients after nasal endoscopic surgery,who were received in the hospital from January 9th 2013 to September 30th 2016,were divided into the treatment group and the control group according to the random number generated by computer,30 cases in each group. The patients in the treatment group were lavaged with 100 mL Wuhuang decoction through sinuses,once a day for 4 weeks as a period; the patients in the control group were lavaged with fluconazole injection,the frequency and the dosage were the same as the treatment group. The expression of IT-8 and ICAM-1 in sinuses secretion before and 1 month after treatment were determined, moreover the efficacy was evaluated by endoscopic examination 6 months after operation. Simultaneously,5 healthy participants from the school were enrolled as the healthy control group,the expression of IT-8 and ICAM-1 were detected in 1 mC recycling residual in nasal cavity after lavaging with 100 mh normal saline. Results The difference had statistical significance (p

Objective To explore the optimal scheme of Chinese medicine Wuhuang decoction for nasal lavage after operation of chronic rhino-sinusitis. Methods 45 patients with chronic rhino-sinusitis diagnosed by otorhinolaryngology Department of the Affiliated Hospital of Traditional Chinese University from April to December 2017 were selected and randomly divided into treatment group 1, treatment group 2 and treatment group 3, each group of 15 patients, who were treated with Wuhuang decoction for nasal lavage. The scores of conscious symptoms, tolerance to nasal lavage and endoscopic Lund-Kennedy were given at half month, one month and three months after operation respectively. Results At half a month of lavage, one month of lavage and three months after operation, the scores of conscious symptoms and Lund-Kennedy scores of nasal endoscopy in the treatment group 1 and the treatment group 2 were lower than those in the treatment group 3, and the differences were statistically significant (P<0.05). At 1 month of lavage and 3 months after operation, there was no significant difference in the scores of conscious symptoms between the treatment group 1 and the treatment group 2(P>0.05). At 1 month of lavage, the tolerance score of nasal lavage in the treatment group 2 was lower than that in the treatment group 1 and the treatment group 3, and the difference was statistically significant (P<0.05). Conclusion The best treatment for chronic rhino-sinusitis after operation is to lavage once a day in the first half month and once every other day. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the clinical effect of trimetazidine combined with carvedilolin in treating chronic heart failure(CHF),and to study its influence on serum NT-pro BNP and c Tn I. Methods A total of 108 patients diagnosed with CHF in our hospital from January 2012 to December 2014 were selected and randomly divided into the routine therapy group(control group),carvedilol group and carvedilol combined with trimetazidine treatment group(combined therapy group),36 cases in each group. The continuous medication treatment lasted for 6 months. The serum NT-pro BNP and c Tn I levels,ultrasound cardiographic indexes in the three groups were compared before and after treatment. Results The total effective rate after 6-month treatment was 88.9% in the combined therapy group and 75.0% in the carvedilol group respectively,which were higher than61.1% in the control group,moreover the combined therapy group was higher than the carvedilol group,the differences were statistically significant(P<0.05);the serum NT-pro BNP and c Tn I levels in the three groups were decreased,the left ventricular enddiastolic diameter(LVEDD) and the left ventricular end systolic diameter(LVESD) were shrunk,and the left ventricular ejection fraction(LVEF) was significantly increased,the differences were statistically significant compared with before treatment(P<0.05);the serum NT-pro BNP and c Tn I levels,LVEDD,LVESD and LVEF had statistically significant differences between the carvedilol group and the combined therapy group with the control group(P<0.05);moreover the NT-pro BNP and c Tn I levels in the combined therapy group were more remarkable than those in the carvedilol group,the differences were statistically significant(P>0.05).Conclusion Trimetazidine combined with carvedilol in treating CHF can improve the clinical therapeutic,reduces the NT-pro BNP and c Tn I levels,protects the myocardial resistance to inflammation,thus effectively improves the cardiac function. [ABSTRACT FROM AUTHOR]

目的 探讨下蹲位导致呼吸困难在不同程度心力衰竭患者中发生比例和对住院时间的评价.方法 根据美国纽约心脏病学会(NYHA)心功能分级标准,选取2014年10月至2016年1月该院心内科收治的分级为Ⅱ、Ⅲ、Ⅳ级的心力衰竭患者,各45例,入院时测量各组下蹲位导致短促呼吸困难出现的人次,所有患者给予标准抗心力衰竭治疗,比较不同的心力衰竭程度与出现症状比例的关系,观察各组内有症状和无症状患者平均住院时间的差异.结果 心力衰竭程度更重的患者下蹲位所致呼吸困难的比例更高,差异有统计学意义(P<0.05);三组入院时检测有症状的患者平均住院时间多于无症状的患者,差异有统计学意义(P<0.05).结论 下蹲位出现短促呼吸困难在严重心功能不全的患者中更易出现,有此症状的患者住院时间更长,预后更差. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)