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107 results on '"MACROLIDE antibiotics"'

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1. Unconventional Fragment Usage Enables a Concise Total Synthesis of (-)-Callyspongiolide.

2. Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination.

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3. Interactions of the Antitumor Macrolide Aplyronine A with Actin and Actin-Related Proteins Established by Its Versatile Photoaffinity Derivatives.

4. Precursor Directed Biosynthesis of an Orthogonally Functional Erythromycin Analogue: Selectivity in the Ribosome Macrolide Binding Pocket.

5. Native Chemical Ligation of Hydrolysis-Resistant 3′-Peptidyl—tRNA Mimics.

6. Direct Entry to Erythronolides via a Cyclic Bis[Allene].

7. Total Synthesis of Bryostatin 7 via C-C Bond-Forming Hydrogenation.

8. Dictyostatin Flexibility Bridges Conformations in Solution and in the β-Tubulin Taxane Binding Site.

9. Isolation, Structural Elucidation, and Absolute Stereochemistry of Enigmazole A, a Cytotoxic Phosphomacrolide from the Papua New Guinea Marine Sponge Cinachyrella enigmatica.

10. Total Synthesis of Enigmazole A from Cinachyrella enigmatica. Bidirectional Bond Constructions with an Ambident 2,4-Disubstituted Oxazole Synthon.

11. Total Synthesis and Stereochemical Assignment of (-)-Ushikulide A.

12. Characterization and Mechanistic Studies of Desil: A Radical S-Adenosyl-L-methionine Enzyme Involved in the Biosynthesis of TDP-D-Desosamine.

13. Total Synthesis and Structure-Activity Investigation of the Marine Natural Product Neopeltolide.

14. Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum.

15. Total Synthesis of (+)-Tedanolide.

16. Total Synthesis of lejimalide A—D and Assessment of the Remarkable Actin-Depolymerizing Capacity of These Polyene Macrolides.

17. Conformations of Laulimalide in DMSO-d6.

18. Zooxanthellamide Cs: Vasoconstrictive Polyhydroxylated Macrolides with the Largest Lactone Ring Size from a Marine Dinoflagellate of Symbiodinium sp.

19. New Efficient Synthesis of Resorcinylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target.

20. Total Synthesis of the Polyene-Polyol Macrolide RK-397, Featuring Cross-Couplings of Alkynylepoxide Modules.

21. Total Syntheses of Amphidinolide T1, T3, T4, and T5.

22. Application of Conformation Design in Acyclic Stereoselection: Total Synthesis of borrelidin as the Crystalline Benzene Solvate.

23. Synthesis of the Antifungal Macrolide Antibiotic (+)-Roxaticin.

24. Asymmetric Synthesis of (2S,3R)-Capreomycidine and the Total Synthesis of Capreomycin IB.

25. Lobatamide C: Total Synthesis, Stereochemical Assignment, Preparation of Simplified Analogues, and V-ATPase Inhibition Studies.

26. Asymmetric Crotylation Reactions in Synthesis of Polypropionate-Derived Macrolides: Application to Total Synthesis of Oleandolide.

27. Total Synthesis of (+)-Zampanolide and (+)-Dactylolide Exploiting a United Strategy.

28. Stereocontrolled Synthesis of (-)-Macrolactin A.

29. Concise Asymmetric Syntheses of Radicicol and Monocillin I.

30. Total Synthesis of Bafilomycin A[sub 1] Relying on Iterative 1,2-Induction in Acyclic Precursors.

31. Precursor-Directed Biosynthesis of 16-Membered Macrolides by the Erythromycin Polyketide Synthase.

32. Application of Complex Aldol Reactions to the Total Synthesis of Phorboxazole B.

33. Stereocontrolled elaboration of natural (-)-polycavernoside A, a powerfully toxic metabolite...

34. Total Synthesis of Bryostatin 2.

35. Synthesis and Absolute Stereochemical Assignment of (+)-Miyakolide.

36. Modeling in organotin chemistry using NMR restraints: A case study on the 9R,12S-[tBu2Sn]2O...

37. Total synthesis of (+)-acutiphycin and (+)-trans-20,21-didehydroacutiphycin.

38. Total syntheses of epothilones A and B.

39. Total syntheses of (+)-ricinelaidic acid lactone and of (-)-gloeosporone based on transition-...

40. Macrocycle formation by catalytic intramolecular cyclopropanation. A new general methodology for...

41. Callipeltoside A: A cytotoxic aminodeoxy sugar-containing macrolide of a new type from the...

44. Application of highly stereocontrolled glycosidations employing 2,6-anhydro-2-thio sugars to the...

46. Enantiospecific synthesis of (-)-alstonerine and (+)-macroline as well as a partial synthesis of...

47. Superstolide A: A potent cytotoxic macrolide of a new type from the New Caledonian deep water...

48. Strategies for macrolide synthesis. A concise approach to protected seco-acids of erythronolides...

49. Cinachyrolide A: A potent cytotoxic macrolide possessing two spiro ketals from marine sponge...