10,540 results
Search Results
2. Increasing understanding of biology concepts through writing scientific papers during the pandemic
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Anisa Anisa and Rhiza Fitri Salsabila
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scientific writing ,online classes ,pandemic ,mastery ,biology concepts ,Theory and practice of education ,LB5-3640 ,Biology (General) ,QH301-705.5 - Abstract
Learning activities were carried out online during the Covid-19 pandemic. Students must improve their ability to write biological scientific papers and apply them in the real world, even presenting them during distance learning. This research is classroom action research that aims to improve the mastery of cell transport concepts and their ability to write scientific papers through online learning. The research was conducted in class XI MIPA 1 at SMA Negeri 2 Purwakarta with 36 students with three cycles of treatment using a constructivist approach with a modified inquiry model. Each cycle is based on a reflection of the previous cycle. The test result data in each cycle is analyzed by comparing the data before and after treatment. Observation data about scientific writing components was analyzed to identify difficulties experienced by students. The results showed that the average learning outcomes for mastery concepts increased by 54.2% using the N-gain score, which means that the treatment significantly impacts mastering the concept of cell transport. The ability of scientific writing papers shows an increase of 11.25%. These classroom action research results show that making scientific writing papers can improve mastery of cell transport, and this may be a recommendation for teaching methods on other concepts. Abstrak Kegiatan pembelajaran dilaksanakan secara daring selama pandemi covid 19. Kemampuan peserta didik dalam menulis karya ilmiah biologi dan menerapkannya dalam dunia nyata penting ditingkatkan, bahkan presentasi saat belajar jarak jauh. Penelitian ini merupakan penelitian tindakan kelas yang bertujuan untuk meningkatkan penguasaan konsep transportasi sel, dan meningkatkan kemampuan menulis karya ilmiah dengan pembelajaran daring. Penelitian ini dilaksanakan di kelas XI MIPA 1 SMA Negeri 2 Purwakarta yang berjumlah 36 siswa, dengan perlakuan 3 siklus menggunakan pendekatan konstruktivisme dengan model inkuiri yang dimodifikasi. Setiap siklus didasarkan pada refleksi dari siklus sebelumnya. Data hasil tes setiap siklus dianalisis dengan membandingkan data sebelum dan sesudah perlakuan. Data observasi tentang komponen penulisan ilmiah dianalisis untuk mengidentifikasi kesulitan yang dialami siswa. Hasil penelitian menunjukkan bahwa rata-rata hasil belajar penguasaan konsep meningkat sebesar 54,2% dengan menggunakan skor N-gain yang berarti perlakuan berpengaruh signifikan terhadap penguasaan konsep transportasi sel. Kemampuan menulis karya ilmiah menunjukkan peningkatan sebesar 11,25%. Hasil penelitian tindakan kelas ini menunjukkan bahwa pembuatan karya tulis ilmiah dapat meningkatkan penguasaan konsep transportasi sel, dan dapat menjadi rekomendasi metode pengajaran pada konsep lainnya.
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- 2023
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3. Paper and packaging industry dynamics during COVID-19 and their strategies for the future
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Gurtu Amulya, Johny Jestin, and Buechse Oliver
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covid-19 ,pandemic ,toilet paper ,bath tissue ,facial tissue ,paper towel ,Production management. Operations management ,TS155-194 ,Personnel management. Employment management ,HF5549-5549.5 - Abstract
Background: The paper examines the "mysterious case of the disappearing toilet paper" during the COVID19 pandemic. Purpose: This paper describes the strategic impacts on paper and packaging supply chains due to the pandemic. Study design/methodology/approach: Structured interviews and qualitative discussions with organizational and supply chain management leaders. Findings/conclusions: Several "behind the scenes" and less well-documented supply chain impacts in the paper and packaging, and logistics industries were discovered. The critical effects observed are: (1) Impact on the manufacturing side was mitigated mainly by implementing CDC guidelines and by the willingness of industry leaders to go above and beyond to shield their employees from economic hardships. (2) The transportation sector has experienced a more severe workforce shortage, amplified by government actions before and during the pandemic. (3) Product specialization, a pre-pandemic strategy for industry participants, turned into a weakness during the pandemic due to unprecedented shifts in demand across sectors. (4) Traditional "lean" supply chain thinking is increasingly making way for a more interconnected "risk avoidance" strategic model. Limitations/future research: The research is limited to organizations in Midwest U.S.A. and one organization in Europe.
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- 2022
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4. Fast-Tracking of Publication Times of Otolaryngology Papers During the COVID-19 Pandemic
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Irit Duek, Nidal Muhanna, Yahav Oron, Yohai Shraga, and Omer J. Ungar
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COVID-19 ,pandemic ,publishing ,research ,otolaryngology head and neck surgery ,ORL-HNS ,Medicine ,Otorhinolaryngology ,RF1-547 - Abstract
Introduction The outbreak of COVID-19 has produced an unprecedented number of trials and articles.
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- 2024
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5. Glycemic Fluctuations of Children and Adolescence Type 1 Diabetes Mellitus and the Impressive Aspects of SARS-CoV-2 Since the Onset of Pandemic Lockdown: A Review Paper
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Daniel Zamanfar, Mobin Ghazaiean, and Mohammad Zahedi
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type 1 diabetes mellitus ,pediatric ,glycemic control ,covid-19 ,pandemic ,Pediatrics ,RJ1-570 - Abstract
Background: The COVID-19 pandemic limited the daily activities of children and adolescents with type 1 diabetes mellitus, and several factors are impacting ongoing care. The role of pandemics on glycemic control is unknown. We plan to assess the glycemic status and the factors that influence it during the pandemic. Objectives: Our goal was to examine the impact of COVID-19 quarantine on the glycemic control of children and adolescents with type 1 diabetes mellitus. Methods: Databases including PubMed, Scopus, Web of Science, and Science Direct, with English-type articles extracted from December 31, 2019, to March 3, 2022, were searched. The article review was based on factors influencing glycemic control in type 1 diabetes mellitus cases younger than 18 years of age during the pandemic period such as psychological factors, telemedicine role, lifestyle changes, various diabetes technology (cost, availability…), caregivers’ role, and socioeconomic factors. Results: We scanned 573 articles as an initial search for titles/abstracts and full-text reviews, and 54 articles remained after title/abstract screening for full-text assessment among which 14 articles (cohort studies) were included. Most studies reported glycemic improvement based on blood glucose metrics while some studies reported stable glycemic control. Although the pre-pandemic glucose profile is important, factors such as telemedicine, diabetes technology, and lifestyle play a more tangible role in improving glycemic control during the pandemic. Conclusions: Overall, the studies did not contain strong evidence that glycemic control worsened in children and adolescents with type 1 diabetes mellitus during the pandemic. Although the assessment was conducted over a short period, long-term multicenter studies would be useful for a more precise assessment of the mentioned potential factors.
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- 2023
6. Exploring the Role of Serology Testing to Strengthen Vaccination Initiatives and Policies for COVID-19 in Asia Pacific Countries and Territories: A Discussion Paper
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Tawee Chotpitayasunondh, Dale Andrew Fisher, Po-Ren Hsueh, Ping-Ing Lee, Katya Nogales Crespo, and Kiat Ruxrungtham
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COVID-19 ,SARS-CoV-2 ,pandemic ,serology tests ,antibody tests ,diagnostic tests ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
This paper provides a comprehensive summary of evidence to explore and position the role of serology testing in the context of coronavirus disease 19 (COVID-19) immunization and policy response in the Asia-Pacific (APAC) region. The document builds on a review of academic literature and existing policies followed by a process of discussion, validation, and feedback by a group of six experts. Six countries and territories—Australia, Hong Kong, India, Indonesia, Thailand, and Taiwan—were sampled to highlight the differing contexts and scenarios in the region. The review includes an overview of (1) the impact of the COVID-19 pandemic, including the emergence of Variants of Concern (VOCs), especially Omicron, (2) the introduction of immunization, (3) the available testing options and potential use of serology testing, (4) the landscape of guidelines and recommendations for their use, and (5) the barriers and challenges to implementing serology testing as a tool to support COVID-19 immunization. Based on the findings, the co-authors propose a set of recommendations to resolve knowledge gaps, to include the use of serology testing as part of the policy response, and to ensure adequate means of implementation. This paper’s target audience includes members of the academic community, medical societies, health providers and practitioners, and decision-makers.
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- 2022
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7. Fast-Tracking of Publication Times of Otolaryngology Papers During the COVID-19 Pandemic.
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Duek, Irit, Muhanna, Nidal, Oron, Yahav, Shraga, Yohai, and Ungar, Omer J.
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COVID-19 pandemic , *OTOLARYNGOLOGY , *COVID-19 , *ELECTRONIC publications - Abstract
Introduction The outbreak of COVID-19 has produced an unprecedented number of trials and articles. Objective To study the impact of the COVID-19 pandemic on otolaryngology-head and neck surgery (ORL-HNS) journal processing times. Methods Original papers search of published in selected ORL-HNS journals in terms of times from submission-to-acceptance (S-A), acceptance-to-first online publication (A-P), and submission-to-online publication (S-P). Papers were divided into those published in the pre-COVID-19 era and those during the COVID-19 era. The latter were further divided into unrelated to COVID-19 and related to COVID-19. Results A total of 487 articles from 5 selected ORL-HNS journals were included, of which 236 (48.5%) were published during the pre-COVID-19 era and 251 (51.5%) were published during the COVID-19 era. Among them, 180 (37%) papers were not related to COVID-19, and 71 (14.5%) were related to COVID-19. The S-A duration of COVID-19-related articles was significantly shorter compared with that of papers submitted in the pre-COVID-19 era and to papers submitted in the COVID-19 era but unrelated to COVID-19 (median 6 to 34 days compared to 65 to 125 and 46 to 127, respectively) in all 5 journals. The most prominent reductions in S-A and S-P times were documented in the laryngology and otology/neurotology disciplines, respectively. Conclusions Processing times of the included papers were significantly shorter in most of the selected ORL-HNS journals during the COVID-19 era compared with the pre-COVID-19 era. COVID-19-related papers were processed more rapidly than non-COVID-19-related papers. These findings testify to the possibility of markedly expediting S-P times and hopefully set a precedent for postpandemic publishing schedules. Level Of Evidence: 5 [ABSTRACT FROM AUTHOR]
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- 2024
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8. The management of surgical patients in the emergency setting during COVID-19 pandemic: the WSES position paper
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De Simone, Belinda, Chouillard, Elie, Sartelli, Massimo, Biffl, Walter L., Di Saverio, Salomone, Moore, Ernest E., Kluger, Yoram, Abu-Zidan, Fikri M., Ansaloni, Luca, Coccolini, Federico, Leppänemi, Ari, Peitzmann, Andrew B., Pagani, Leonardo, Fraga, Gustavo P., Paolillo, Ciro, Picetti, Edoardo, Valentino, Massimo, Pikoulis, Emmanouil, Baiocchi, Gian Luca, and Catena, Fausto
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- 2021
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9. Late phase of COVID‐19 pandemic in General Cardiology. A position paper of the ESC Council for Cardiology Practice
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Dimitrios Richter, Luigina Guasti, Friedrich Koehler, Alessandro Squizzato, Stefano Nistri, Ruxandra Christodorescu, Francois Dievart, Giovanni Gaudio, Riccardo Asteggiano, and Marc Ferrini
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SARS‐CoV‐2 ,COVID‐19 ,Late phase ,Post‐COVID ,‘Long COVID‐19’ illness ,Pandemic ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Cardiovascular (CV) engagement in coronavirus disease 2019 (COVID‐19) is a huge determinant of prognosis during the acute phase of the disease. However, little is known about the potential chronic implications of the late phase of COVID‐19 and about the appropriate approach to these patients. Heart failure, type 1 and type 2 myocardial infarction, arrhythmias, myocarditis, pulmonary fibrosis, and thrombosis have been shown to be related to severe acute respiratory syndrome coronavirus 2 infection, and a ‘long COVID‐19’ illness has been recognized with fatigue, chest pain, and dyspnoea among the most frequent symptoms reported after discharge from hospital. This paper focuses on some open questions that cardiologists are going to face during the next months in a general cardiology outpatient clinic, in particular how to evaluate a ‘post‐COVID’ patient during follow‐up of CV complications of the acute phase and how to manage new CV symptoms that could be the consequence, at least in part, of heart/vessels and/or lung involvement of the previous virus infection. Present symptoms and signs, history of previous CV disease (both preceding COVID‐19 and occurring during viral infection), and specific laboratory and imaging measurements during the acute phase may be of interest in focusing on how to approach the clinical evaluation of a post‐COVID patient and how to integrate in our standard of care the new information on COVID‐19, possibly in a multidisciplinary view. Dealing with the increased COVID‐associated CV risk burden and becoming acquainted with potential new e‐cardiology approaches aimed at integrating the cardiology practice are relevant new challenges brought by severe acute respiratory syndrome coronavirus 2 infection and its sequelae.
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- 2021
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10. Fast-Tracking of Publication Times of Otolaryngology Papers During the COVID-19 Pandemic.
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Duek, Irit, Muhanna, Nidal, Horowitz, Gilad, Warshavsky, Anton, Oron, Yahav, Shraga, Yohai, and Ungar, Omer J.
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COVID-19 pandemic , *ELECTRONIC publications , *OTOLARYNGOLOGY , *COVID-19 , *ELECTRONIC information resource searching - Abstract
To study the impact of the COVID-19 pandemic on journal processing times before publication in the field of otolaryngology-head and neck surgery (ORL-HNS). Online search of original papers published in selected ORL-HNS journals in terms of times from submission to acceptance (S-A), acceptance to first online publication (A-P), and submission to online publication (S-P). Papers were divided into those published in the pre-COVID-19 era and those during the COVID-19 era. The latter were further divided into unrelated to COVID-19 and related to COVID-19. A total of 487 articles from 5 selected ORL-HNS journals were included, of which 236 (48.5%) were published during the pre-COVID-19 era and 251 (51.5%) were published during the COVID-19 era. Among them, 180 (37%) papers were not related to COVID-19, and 71 (14.5%) were related to COVID-19. The S-A duration of COVID-19-related articles was significantly shorter compared to papers submitted in the pre-COVID-19 era and to papers submitted in the COVID-19 era but unrelated to COVID-19 (median 6–34 days compared to 65–125 and 46–127, respectively) in all 5 journals. The most prominent reductions in S-A and S-P times were documented in the laryngology and otology/neurotology disciplines, respectively. Processing times of the included papers were significantly shorter in most of the selected ORL-HNS journals during the COVID-19 era compared to the pre-COVID-19 era. COVID-19-related papers were processed more rapidly than non-COVID-19-related papers. These findings testify to the possibility of markedly expediting S-P times and hopefully set a precedent for post-pandemic publishing schedules. [ABSTRACT FROM AUTHOR]
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- 2023
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11. IN THIS ISSUE: Open call papers, and more papers and commentaries on the impact of COVID-19 on the food system
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Duncan Hilchey
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Editorial ,Pandemic ,COVID-19 ,Agriculture ,Human settlements. Communities ,HT51-65 - Abstract
First paragraphs: Have we finally turned the corner on COVID-19? Just maybe. The world is still reeling from the pandemic, and the delta variant is taking its toll presently, but the winds of change do seem to be shifting in our favor. After publishing more than a year and a half’s worth of research-based papers and commentaries on COVID-19 and its impact on the food system, we are taking a kind of odd pleasure in finally publishing content on a broader range of issues. Food systems work is (or should be) a veritable beehive of activity on all fronts, at all levels, at all times: racial equity, family farm resilience, climate change, building out our food security infrastructure, and so on require constant simultaneous attention, each of these key issues being a piece of an interlocking resilience puzzle. . . .
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- 2021
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12. COVID-19 and Substance Use Disorders: Recommendations to a Comprehensive Healthcare Response. An International Society of Addiction Medicine (ISAM) Practice and Policy Interest Group Position Paper
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Ali Farhoudian, Alexander Baldacchino, Nicolas Clark, Gilberto Gerra, Hamed Ekhtiari, Geert Dom, Azarakhsh Mokri, Mandana Sadeghi, Pardis Nematollahi, Maryanne Demasi, Christian G. Schütz, Seyed Mohammadreza Hashemian, Payam Tabarsi, Susanna Galea-singer, Giuseppe Carrà, Thomas Clausen, Christos Kouimtsidis, Serenella Tolomeo, Seyed Ramin Radfar, and Emran Mohammad Razaghi
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coronavirus ,coronavirus disease 2019 (covid-19) ,pandemic ,public health ,substance use disorder ,addiction medicine ,harm reduction ,policy ,methadone ,opioid substitution therapy ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Coronavirus disease 2019 (COVID-19) is escalating all over the world and has higher morbidities and mortalities in certain vulnerable populations. People Who Use Drugs (PWUD) are a marginalized and stigmatized group with weaker immunity responses, vulnerability to stress, poor health conditions, high-risk behaviors, and lower access to health care services. These conditions put them at a higher risk of COVID-19 infection and its complications. In this paper, an international group of experts on addiction medicine, infectious diseases, and disaster psychiatry explore the possible raised concerns in this issue and provide recommendations to manage the comorbidity of COVID-19 and Substance Use Disorder (SUD).
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- 2020
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13. Pharmacists roles and responsibilities during epidemics and pandemics in Saudi Arabia: An opinion paper from the Saudi Society of clinical pharmacy
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Hisham A. Badreldin, Shahad Raslan, Hajar Almudaiheem, Bedor Alomari, Sahar Almowaina, Hala Joharji, Mohammad Alawagi, and Ahmed Al-jedai
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Pandemic ,COVID-19 ,Pharmacist ,Policymaker ,Therapeutics. Pharmacology ,RM1-950 - Abstract
On the 2nd of March 2020, Kingdom of Saudi Arabia confirmed its first case of the coronavirus's newly emerging strain, causing coronavirus disease 2019 (COVID-19). Soon after, the number of confirmed cases started to increase nationally. In light of the emerging outbreak, all healthcare professionals, including pharmacists, began to function with maximum capacity and efforts. The Saudi Society of Clinical Pharmacy (SSCP) acknowledges the substantial impact pharmacists can play during outbreaks. Based on the existing scientific knowledge during this outbreak, the SSCP established an expert writing task force to conceptualize and draft the proposed recommendations that highlights the roles and responsibilities of pharmacists during epidemics and pandemics. The SSCP writing task force issued 28 recommendations. In addition to the national and institutional guidelines, these recommendations could serve as guidance for the impacted entities.
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- 2020
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14. Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic
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Ana P.M. Tavares, Cristina E. A. Sousa, Rodrigo Martins, Maria Teresa Cruz, Ana C. Marques, Elvira Fortunato, Felismina T.C. Moreira, M. Goreti F. Sales, A. Rita Cardoso, Tomás Pinheiro, Ana Matos, and Universidade do Minho
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Diagnostic methods ,Coronavirus disease 2019 (COVID-19) ,Computer science ,General Chemical Engineering ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Immunology ,02 engineering and technology ,Viral antigen ,Peptides and proteins ,Diagnostic tools ,01 natural sciences ,Biopolymers ,Pandemic ,Medical diagnosis ,Antigens ,QD1-999 ,Science & Technology ,SARS-CoV-2 ,010401 analytical chemistry ,General Chemistry ,Paper based ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,3. Good health ,Chemistry ,Risk analysis (engineering) ,Perspective ,0210 nano-technology - Abstract
The appearance and quick spread of the new severe acute respiratory syndrome coronavirus disease, COVID-19, brought major societal challenges. Importantly, suitable medical diagnosis procedures and smooth clinical management of the disease are an emergent need, which must be anchored on novel diagnostic methods and devices. Novel molecular diagnostic tools relying on nucleic acid amplification testing have emerged globally and are the current gold standard in COVID-19 diagnosis. However, the need for widespread testing methodologies for fast, effective testing in multiple epidemiological scenarios remains a crucial step in the fight against the COVID-19 pandemic. Biosensors have previously shown the potential for cost-effective and accessible diagnostics, finding applications in settings where conventional, laboratorial techniques may not be readily employed. Paper- and cellulose-based biosensors can be particularly relevant in pandemic times, for the renewability, possibility of mass production with sustainable methodologies, and safe environmental disposal. In this review, paper-based devices and platforms targeting SARS-CoV-2 are showcased and discussed, as a means to achieve quick and low-cost PoC diagnosis, including detection methodologies for viral genomic material, viral antigen detection, and serological antibody testing. Devices targeting inflammatory markers relevant for COVID-19 are also discussed, as fast, reliable bedside diagnostic tools for patient treatment and follow-up., The authors acknowledge funding through projects Eco2Covid (POCI-01-02B7-FEDER-068174) and TecniCov (POCI-01-02B7-FEDER-069745), co-funded by FEDER through COMPETE2020 and Lisboa2020. T.P., A.R.C. and A.C.M. acknowledge funding to National Foundation for Science and Technology, I.P., FCT, through their PhD grants, references DFA/BD/8606/2020, SFRH/BD/130107/2017 and SFRH/BD/115173/2016, respectively, info:eu-repo/semantics/publishedVersion
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- 2021
15. The 2019–2020 novel coronavirus (severe acute respiratory syndrome coronavirus 2) pandemic: A joint american college of academic international medicine-world academic council of emergency medicine multidisciplinary COVID-19 working group consensus paper
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Stanislaw P Stawicki, Rebecca Jeanmonod, Andrew C Miller, Lorenzo Paladino, David F Gaieski, Anna Q Yaffee, Annelies De Wulf, Joydeep Grover, Thomas J Papadimos, Christina Bloem, Sagar C Galwankar, Vivek Chauhan, Michael S Firstenberg, Salvatore Di Somma, Donald Jeanmonod, Sona M Garg, Veronica Tucci, Harry L Anderson, Lateef Fatimah, Tamara J Worlton, Siddharth P Dubhashi, Krystal S Glaze, Sagar Sinha, Ijeoma Nnodim Opara, Vikas Yellapu, Dhanashree Kelkar, Ayman El-Menyar, Vimal Krishnan, S Venkataramanaiah, Yan Leyfman, Hassan Ali Saoud Al Thani, Prabath W B Nanayakkara, Sudip Nanda, Eric Cioè-Peña, Indrani Sardesai, Shruti Chandra, Aruna Munasinghe, Vibha Dutta, Silvana Teixeira Dal Ponte, Ricardo Izurieta, Juan A Asensio, and Manish Garg
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2019-ncov ,coronavirus ,covid-19 ,global impact ,international health security ,pandemic ,severe acute respiratory syndrome coronavirus 2 ,Infectious and parasitic diseases ,RC109-216 - Abstract
What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in December 2019, was later determined to be coronavirus disease 2019 (COVID-19). The pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel Betacoronavirus, was subsequently isolated as the causative agent. SARS-CoV-2 is transmitted by respiratory droplets and fomites and presents clinically with fever, fatigue, myalgias, conjunctivitis, anosmia, dysgeusia, sore throat, nasal congestion, cough, dyspnea, nausea, vomiting, and/or diarrhea. In most critical cases, symptoms can escalate into acute respiratory distress syndrome accompanied by a runaway inflammatory cytokine response and multiorgan failure. As of this article's publication date, COVID-19 has spread to approximately 200 countries and territories, with over 4.3 million infections and more than 290,000 deaths as it has escalated into a global pandemic. Public health concerns mount as the situation evolves with an increasing number of infection hotspots around the globe. New information about the virus is emerging just as rapidly. This has led to the prompt development of clinical patient risk stratification tools to aid in determining the need for testing, isolation, monitoring, ventilator support, and disposition. COVID-19 spread is rapid, including imported cases in travelers, cases among close contacts of known infected individuals, and community-acquired cases without a readily identifiable source of infection. Critical shortages of personal protective equipment and ventilators are compounding the stress on overburdened healthcare systems. The continued challenges of social distancing, containment, isolation, and surge capacity in already stressed hospitals, clinics, and emergency departments have led to a swell in technologically-assisted care delivery strategies, such as telemedicine and web-based triage. As the race to develop an effective vaccine intensifies, several clinical trials of antivirals and immune modulators are underway, though no reliable COVID-19-specific therapeutics (inclusive of some potentially effective single and multi-drug regimens) have been identified as of yet. With many nations and regions declaring a state of emergency, unprecedented quarantine, social distancing, and border closing efforts are underway. Implementation of social and physical isolation measures has caused sudden and profound economic hardship, with marked decreases in global trade and local small business activity alike, and full ramifications likely yet to be felt. Current state-of-science, mitigation strategies, possible therapies, ethical considerations for healthcare workers and policymakers, as well as lessons learned for this evolving global threat and the eventual return to a “new normal” are discussed in this article.
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- 2020
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16. The management of surgical patients in the emergency setting during COVID-19 pandemic: the WSES position paper
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Ari Leppanemi, Belinda De Simone, Leonardo Pagani, Edoardo Picetti, Emmanouil Pikoulis, Fausto Catena, Salomone Di Saverio, Elie Chouillard, Gian Luca Baiocchi, A. B. Peitzmann, Federico Coccolini, Luca Ansaloni, Yoram Kluger, Gustavo Pereira Fraga, Walter L. Biffl, Massimo Sartelli, Massimo Valentino, Ernest E. Moore, Fikri M. Abu-Zidan, and Ciro Paolillo
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Infectious Disease Transmission, Patient-to-Professional ,Isolation (health care) ,Non operative management ,MEDLINE ,lcsh:Surgery ,030204 cardiovascular system & hematology ,Global Health ,Open surgery ,Perioperative Care ,03 medical and health sciences ,Postoperative care ,0302 clinical medicine ,COVID-19 Testing ,Personal protective equipment ,Health care ,Medicine ,Humans ,030212 general & internal medicine ,Pandemics ,Infection Control ,Pandemic ,business.industry ,SARS-CoV-2 ,Follow-up ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,COVID-19 ,Emergency department ,lcsh:RD1-811 ,lcsh:RC86-88.9 ,medicine.disease ,Trauma surgery ,Mass-casualty incident ,Surgical Procedures, Operative ,2019-nCoV ,Emergency Medicine ,Emergency surgery ,Laparoscopy ,Screening ,Position paper ,Surgery ,Medical emergency ,Emergencies ,business ,Research Article - Abstract
Background Since the COVID-19 pandemic has occurred, nations showed their unpreparedness to deal with a mass casualty incident of this proportion and severity, which resulted in a tremendous number of deaths even among healthcare workers. The World Society of Emergency Surgery conceived this position paper with the purpose of providing evidence-based recommendations for the management of emergency surgical patients under COVID-19 pandemic for the safety of the patient and healthcare workers. Method A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) through the MEDLINE (PubMed), Embase and SCOPUS databases. Synthesis of evidence, statements and recommendations were developed in accordance with the GRADE methodology. Results Given the limitation of the evidence, the current document represents an effort to join selected high-quality articles and experts’ opinion. Conclusions The aim of this position paper is to provide an exhaustive guidelines to perform emergency surgery in a safe and protected environment for surgical patients and for healthcare workers under COVID-19 and to offer the best management of COVID-19 patients needing for an emergency surgical treatment. We recommend screening for COVID-19 infection at the emergency department all acute surgical patients who are waiting for hospital admission and urgent surgery. The screening work-up provides a RT-PCR nasopharyngeal swab test and a baseline (non-contrast) chest CT or a chest X-ray or a lungs US, depending on skills and availability. If the COVID-19 screening is not completed we recommend keeping the patient in isolation until RT-PCR swab test result is not available, and to manage him/she such as an overt COVID patient. The management of COVID-19 surgical patients is multidisciplinary. If an immediate surgical procedure is mandatory, whether laparoscopic or via open approach, we recommend doing every effort to protect the operating room staff for the safety of the patient.
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- 2021
17. India's need for long-term solutions to COVID-19-like pandemics: A policy paper by Organized Medicine Academic Guild
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Suneela Garg, Raman Kumar, Sunil D Khaparde, Sunil Kumar Raina, Praveen Agarwal, S Natrajan, Sagar Galvankar, Ishwar Gilada, Ramesh Bhatt, A C Dhariwal, and Uday Bodhankar
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medicine.medical_specialty ,Economic growth ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Public health ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,paper ,COVID-19-like pandemics ,030209 endocrinology & metabolism ,Mindset ,Invited Articles ,Term (time) ,03 medical and health sciences ,0302 clinical medicine ,Organized Medicine Academic Guild ,Guild ,Pandemic ,long-term solutions ,medicine ,Medicine ,030212 general & internal medicine ,business ,policy - Abstract
The entire world seems to have responded to COVID-19 pandemic in a knee-jerk manner with a short mindset without building on the existing strengths of public health infrastructure. National governments cannot be blamed for this as we are dealing with a crisis that comes once in a lifetime. Realising this, the Organized Medicine Academic Guild (OMAG) an association of major health associations in this country has suggested measures for long-term solutions to COVID-19-like pandemics in the form of a policy paper by OMAG.
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- 2021
18. IN THIS ISSUE: COVID-19 commentaries and open call papers
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Duncan Hilchey
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Editorial ,COVID-19 ,Pandemic ,Agriculture ,Human settlements. Communities ,HT51-65 - Abstract
First paragraph: The cover of this open call issue of JAFSCD is a Google Earth shot of the Schrebergartens outside Mannheim, Germany. Schrebergartens are named for Dr. Moritz Schreber, a Leipzig University professor who specialized in pediatric health. He is infamous for advocating that children strictly obey adults, but he also suggested that city children should have access to fresh air and green space. Schrebergartens are similar in some respects to the Russian dacha, often including “tiny houses,” raised beds, perennials—and lots of garden gnomes. Entire colonies of Schrebergartens have been established since WWII. . . .
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- 2020
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19. Exploring the Role of Serology Testing to Strengthen Vaccination Initiatives and Policies for COVID-19 in Asia Pacific Countries and Territories: A Discussion Paper.
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Chotpitayasunondh, Tawee, Fisher, Dale Andrew, Hsueh, Po-Ren, Lee, Ping-Ing, Nogales Crespo, Katya, and Ruxrungtham, Kiat
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COVID-19 pandemic , *SEROLOGY , *ROUTINE diagnostic tests , *HEALTH policy , *IMMUNIZATION - Abstract
This paper provides a comprehensive summary of evidence to explore and position the role of serology testing in the context of coronavirus disease 19 (COVID-19) immunization and policy response in the Asia-Pacific (APAC) region. The document builds on a review of academic literature and existing policies followed by a process of discussion, validation, and feedback by a group of six experts. Six countries and territories—Australia, Hong Kong, India, Indonesia, Thailand, and Taiwan—were sampled to highlight the differing contexts and scenarios in the region. The review includes an overview of (1) the impact of the COVID-19 pandemic, including the emergence of Variants of Concern (VOCs), especially Omicron, (2) the introduction of immunization, (3) the available testing options and potential use of serology testing, (4) the landscape of guidelines and recommendations for their use, and (5) the barriers and challenges to implementing serology testing as a tool to support COVID-19 immunization. Based on the findings, the co-authors propose a set of recommendations to resolve knowledge gaps, to include the use of serology testing as part of the policy response, and to ensure adequate means of implementation. This paper's target audience includes members of the academic community, medical societies, health providers and practitioners, and decision-makers. [ABSTRACT FROM AUTHOR]
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- 2022
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20. Does Peer Reviewing for COVID-19-Related Papers Still Work?
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Octavio Orellana-Serradell, Magda C. Díaz, María Fernanda González, Myriam Gutiérrez, Daniela Herrera, Daniela Jara, Diego Maureira, Jenny L. Ruiz-Fuentes, Sofía Sanhueza, and Lisette Leyton
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coronavirus ,severe acute respiratory syndrome ,SARS-CoV-2 ,infectious disease ,pandemic ,scientific rigor ,Bibliography. Library science. Information resources - Published
- 2020
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21. ANMCO POSITION PAPER: Considerations on in-hospital cardiological consultations and cardiology outpatient clinics during the COVID-19 pandemic
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Enzo Amodeo, Nadia Aspromonte, Pasquale Caldarola, Michele Massimo Gulizia, Massimo Imazio, Furio Colivicchi, Serafina Valente, Stefano Domenicucci, Giuseppina Maura Francese, Andrea Di Lenarda, Domenico Gabrielli, Fortunato Scotto di Uccio, Stefano Urbinati, Manlio Cipriani, Adriano Murrone, and Loris Roncon
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medicine.medical_specialty ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Pneumonia, Viral ,Cardiology ,030204 cardiovascular system & hematology ,Ambulatory Care Facilities ,03 medical and health sciences ,Betacoronavirus ,0302 clinical medicine ,COVID-19 Testing ,Contagion risk ,Cardiological consultations ,Epidemiology ,Pandemic ,medicine ,Cardiology outpatient clinics ,Outpatient clinic ,Humans ,AcademicSubjects/MED00200 ,030212 general & internal medicine ,Personal protective equipment ,Pandemics ,Referral and Consultation ,Infection Control ,business.industry ,Clinical Laboratory Techniques ,SARS-CoV-2 ,COVID-19 ,Articles ,medicine.disease ,Cardiovascular disease ,Telemedicine ,Cardiovascular emergencies ,Cardiovascular Diseases ,Position paper ,Medical emergency ,Cardiology and Cardiovascular Medicine ,business ,Coronavirus Infections ,Algorithms - Abstract
Infections by SARS CoV2 - COVID-19 have become in a short time a worldwide health emergency. Due to cardiovascular implications of COVID-19 and to very frequent previous cardiovascular disorders of COVID-19 patients, it is presently crucial that Cardiologists are fully aware of COVID-19 related epidemiological, pathophysiological and therapeutic problems, in order to manage at best the present emergency by appropriate protocols developed on the basis of the competences acquired and shared on the field. The aim of this document is to propose algorithms for the management of cardiovascular diseases during COVID-19 emergency with the objective of providing patients with optimal care, minimizing contagion risk and appropriately managing personal protective equipment.
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- 2020
22. The 2019–2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus Paper
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Hassan Al Thani, Tamara J. Worlton, Sagar Sinha, Sudip Nanda, Ricardo Izurieta, Sagar Galwankar, Andrew C. Miller, Stanislaw P Stawicki, Yan Leyfman, Vikas Yellapu, Eric Cioè-Peña, Manish Garg, Veronica Tucci, Joydeep Grover, Vimal Krishnan, Harry L. Anderson, Ijeoma Nnodim Opara, Rebecca Jeanmonod, Sona M Garg, Annelies De Wulf, Ayman El-Menyar, Silvana Teixeira Dal Ponte, Aruna Munasinghe, Prabath W. B. Nanayakkara, Thomas J Papadimos, S Venkataramanaiah, Anna Q Yaffee, Vibha Dutta, Dhanashree S. Kelkar, Donald Jeanmonod, Michael S. Firstenberg, David F. Gaieski, Krystal S Glaze, Indrani Sardesai, Juan A. Asensio, Salvatore Di Somma, Christina Bloem, Lorenzo Paladino, Shruti Chandra, Vivek Chauhan, Siddharth P. Dubhashi, and Lateef Fatimah
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medicine.medical_specialty ,Telemedicine ,Isolation (health care) ,030231 tropical medicine ,coronavirus ,medicine.disease_cause ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,0302 clinical medicine ,Consensus Paper ,Pandemic ,Health care ,Sore throat ,Medicine ,lcsh:RC109-216 ,030212 general & internal medicine ,Intensive care medicine ,Coronavirus ,business.industry ,Public health ,pandemic ,COVID-19 ,Triage ,Infectious Diseases ,2019-nCoV ,medicine.symptom ,International Health Security ,business ,global impact ,severe acute respiratory syndrome coronavirus 2 - Abstract
What started as a cluster of patients with a mysterious respiratory illness in Wuhan, China, in December 2019, was later determined to be coronavirus disease 2019 (COVID-19). The pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel Betacoronavirus, was subsequently isolated as the causative agent. SARS-CoV-2 is transmitted by respiratory droplets and fomites and presents clinically with fever, fatigue, myalgias, conjunctivitis, anosmia, dysgeusia, sore throat, nasal congestion, cough, dyspnea, nausea, vomiting, and/or diarrhea. In most critical cases, symptoms can escalate into acute respiratory distress syndrome accompanied by a runaway inflammatory cytokine response and multiorgan failure. As of this article's publication date, COVID-19 has spread to approximately 200 countries and territories, with over 4.3 million infections and more than 290,000 deaths as it has escalated into a global pandemic. Public health concerns mount as the situation evolves with an increasing number of infection hotspots around the globe. New information about the virus is emerging just as rapidly. This has led to the prompt development of clinical patient risk stratification tools to aid in determining the need for testing, isolation, monitoring, ventilator support, and disposition. COVID-19 spread is rapid, including imported cases in travelers, cases among close contacts of known infected individuals, and community-acquired cases without a readily identifiable source of infection. Critical shortages of personal protective equipment and ventilators are compounding the stress on overburdened healthcare systems. The continued challenges of social distancing, containment, isolation, and surge capacity in already stressed hospitals, clinics, and emergency departments have led to a swell in technologically-assisted care delivery strategies, such as telemedicine and web-based triage. As the race to develop an effective vaccine intensifies, several clinical trials of antivirals and immune modulators are underway, though no reliable COVID-19-specific therapeutics (inclusive of some potentially effective single and multi-drug regimens) have been identified as of yet. With many nations and regions declaring a state of emergency, unprecedented quarantine, social distancing, and border closing efforts are underway. Implementation of social and physical isolation measures has caused sudden and profound economic hardship, with marked decreases in global trade and local small business activity alike, and full ramifications likely yet to be felt. Current state-of-science, mitigation strategies, possible therapies, ethical considerations for healthcare workers and policymakers, as well as lessons learned for this evolving global threat and the eventual return to a 'new normal' are discussed in this article.
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- 2020
23. IN THIS ISSUE: Open Call Papers and Early Responses to COVID-19
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Duncan Hilchey
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Editorial ,COVID-19 ,Pandemic ,Contents ,Agriculture ,Human settlements. Communities ,HT51-65 - Abstract
First paragraphs: On behalf of the JAFSCD staff and community, I would like to extend condolences to anyone in the JAFSCD community—our shareholders—who have lost family members or colleagues during the COVID-19 pandemic. We are with you. We also wish anyone who has contracted the virus our best wishes for a speedy and full recovery, and hope for a better future for those whose lives have been turned topsy-turvey by the pandemic. On May 26, 2020, the United States officially reported losing 100,000 individuals, many of whom were vulnerable to this plague—especially the poor, people of color, the elderly, and essential workers. This represents a moral and systemic failure for the world’s richest country. As Americans are cobbling together an assortment of food provisioning strategies, what we are witnessing is a demonstration of just how fragile American food security is in a time of crisis. However, as you’ll see in this open call issue, COVID-19 is also highlighting our strengths and creativity, and what we can build on in a future food system that contributes to our overall health, well-being, and social resiliency. . . .
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- 2020
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24. Pharmacists roles and responsibilities during epidemics and pandemics in Saudi Arabia: An opinion paper from the Saudi Society of clinical pharmacy.
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Badreldin, Hisham A., Raslan, Shahad, Almudaiheem, Hajar, Alomari, Bedor, Almowaina, Sahar, Joharji, Hala, Alawagi, Mohammad, and Al-jedai, Ahmed
- Abstract
On the 2nd of March 2020, Kingdom of Saudi Arabia confirmed its first case of the coronavirus's newly emerging strain, causing coronavirus disease 2019 (COVID-19). Soon after, the number of confirmed cases started to increase nationally. In light of the emerging outbreak, all healthcare professionals, including pharmacists, began to function with maximum capacity and efforts. The Saudi Society of Clinical Pharmacy (SSCP) acknowledges the substantial impact pharmacists can play during outbreaks. Based on the existing scientific knowledge during this outbreak, the SSCP established an expert writing task force to conceptualize and draft the proposed recommendations that highlights the roles and responsibilities of pharmacists during epidemics and pandemics. The SSCP writing task force issued 28 recommendations. In addition to the national and institutional guidelines, these recommendations could serve as guidance for the impacted entities. [ABSTRACT FROM AUTHOR]
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- 2020
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25. Late phase of COVID‐19 pandemic in General Cardiology. A position paper of the ESC Council for Cardiology Practice
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Marc Ferrini, Alessandro Squizzato, Stefano Nistri, Giovanni Gaudio, Friedrich Koehler, Luigina Guasti, Francois Dievart, Dimitrios J. Richter, Ruxandra Christodorescu, and Riccardo Asteggiano
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medicine.medical_specialty ,‘Long COVID-19’ illness ,Myocarditis ,Cardiology ,Disease ,030204 cardiovascular system & hematology ,Chest pain ,ESC and HFA Paper ,ESC and HFA Papers ,SARS‐CoV‐2 ,03 medical and health sciences ,0302 clinical medicine ,Post-Acute COVID-19 Syndrome ,COVID‐19 ,Internal medicine ,Pandemic ,medicine ,Diseases of the circulatory (Cardiovascular) system ,Outpatient clinic ,Humans ,030212 general & internal medicine ,Myocardial infarction ,Pandemics ,Late phase ,business.industry ,Wearables ,SARS-CoV-2 ,General cardiology ,COVID-19 ,Pneumonia ,medicine.disease ,Telemedicine ,‘Long COVID‐19’ illness ,RC666-701 ,Post-COVID ,Heart failure ,Post‐COVID ,Myocardial injury ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Digital health - Abstract
Cardiovascular (CV) engagement in coronavirus disease 2019 (COVID‐19) is a huge determinant of prognosis during the acute phase of the disease. However, little is known about the potential chronic implications of the late phase of COVID‐19 and about the appropriate approach to these patients. Heart failure, type 1 and type 2 myocardial infarction, arrhythmias, myocarditis, pulmonary fibrosis, and thrombosis have been shown to be related to severe acute respiratory syndrome coronavirus 2 infection, and a ‘long COVID‐19’ illness has been recognized with fatigue, chest pain, and dyspnoea among the most frequent symptoms reported after discharge from hospital. This paper focuses on some open questions that cardiologists are going to face during the next months in a general cardiology outpatient clinic, in particular how to evaluate a ‘post‐COVID’ patient during follow‐up of CV complications of the acute phase and how to manage new CV symptoms that could be the consequence, at least in part, of heart/vessels and/or lung involvement of the previous virus infection. Present symptoms and signs, history of previous CV disease (both preceding COVID‐19 and occurring during viral infection), and specific laboratory and imaging measurements during the acute phase may be of interest in focusing on how to approach the clinical evaluation of a post‐COVID patient and how to integrate in our standard of care the new information on COVID‐19, possibly in a multidisciplinary view. Dealing with the increased COVID‐associated CV risk burden and becoming acquainted with potential new e‐cardiology approaches aimed at integrating the cardiology practice are relevant new challenges brought by severe acute respiratory syndrome coronavirus 2 infection and its sequelae.
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- 2021
26. ‘We went from understanding, to disappointment, resentment and often grief all in the space of 6 months’ A qualitative study of the stories of family carers of care home residents during COVID-19 pandemic in 2020. East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series
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Hinsliff-Smith, K., de Vries, Kay, Padley, Wendy, Brown, Jayne, and Griffiths, Sarah Ellen
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relatives ,sense of loss ,covid-19 ,communication ,pandemic ,death ,qualitative ,residents ,care homes ,restricted visiting ,UK - Abstract
When the WHO announced a global pandemic in response to COVID-19, individual countries reacted in a similar way with care homes closing their doors to visits, including visits from family members. The UK was no different, initially they closed to protect care home residents during a period of uncertainty, particularly as many were frail, with complex health needs and classed as vulnerable to the virus. This did however, create a sustained period of uncertainty for family members as well as the wider UK care home community. During 2020, 13 family carers in the UK shared their experiences through this period of COVID related enforced lockdowns, in total 27 interviews were conducted. Our findings and three themes narrate to time points when we were conducting interviews and were often linked to key changes in policy, often in the wider society but not conveyed into care home practices or visiting policies. Three overarching themes are described: Understanding and Acceptance, Disappointment and Resentment, Grief and Sense of Loss
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- 2023
27. Opinion Paper : Importance of global communication to combat global pandemics: Lessons from the HIV Online Provider Education programme: Special Collection: UNAIDS Targets for 2030
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Airewele, Efeose A., Sunpath, Henry, Moosa, Mahomed-Yunus S., and Gandhi, Rajesh T.
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HIV ,AIDS ,COVID-19 ,COVID ,pandemic ,communication ,collaboration ,global health ,public health - Abstract
In many ways, the coronavirus disease 2019 (COVID-19) pandemic mirrors the challenges, lessons and opportunities of the HIV pandemic. In this article, we argue that global pandemics such as COVID-19 and HIV require a global response. We highlight the HIV Online Provider Education (HOPE) programme as an example of the importance of global communication when combating a pandemic. From both the COVID-19 and HIV pandemics, we have learned that to optimise health worldwide, it is necessary to have effective and efficient means of swiftly sharing experiences, expertise, best practices and guidelines. To prepare for the next public health emergency, clinicians and researchers must put in place and promote effective programmes for global communication.
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- 2023
28. The COVID-19 Pandemic and the Need for an Integrated and Equitable Approach: An International Expert Consensus Paper
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Sergio Pillon, Mariella Catalano, Benjamin Brenner, Zsolt Pecsvarady, Ismail Elalamy, Joseph Lewis, Jean-Claude Wautrecht, D. Olinic, Vincent Maréchal, Mouna Sassi, Isabelle Mahé, Anna Falanga, Nusrat Jabeen, Charles A. Carter, Mary-Paula Colgan, Alexander Makatsariya, Alfonso Tafur, Kasse Aa, Tazi Mezalek Zoubida, Meletios-Athanasios Dimopoulos, Michèle Sabbah, Darko Antic, Yiannis Theodorou, Alex C. Spyropoulos, Vladimir Chekhonin, Meganathan Kannan, Katalin Farkas, Peter Klein-Wegel, Job Harenberg, P Massamba Mbaye, Joseph Gligorov, Manuel Monreal Bosch, Grigoris T. Gerotziafas, Pier Luigi Antignani, Hikmat Abdel-Razeq, James D. Douketis, Gerit Schernthaner, Petros Agathaggelou, Ali T. Taher, Jawed Fareed, Essam Abo Elnazar, Irina Panovska-Stavridis, Patrick Van Dreden, Fabio Leivano, Gerry Fowkes, Fakiha Siddiqui, Mark A. Ligocki, Tishya Indran, Kostantinos Konstantinidis, Bulent Kantarcioglu, Jin Shiomura, Bahare Fazeli, Chryssa Papageorgiou, Yongquan Gu, Anny Slama-Schwok, Eduardo Ramacciotti, Zenguo Zhai, Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Università degli Studi di Milano = University of Milan (UNIMI), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Sechenov First Moscow State Medical University, Campbell University [Buies Creek, NC, USA] (CU), University of Karachi, Heidelberg University, Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Loyola University [Chicago], Cyprus Institute (CyI), University of Belgrade [Belgrade], Nuova Villa Claudia [Rome, Italy] (NVC), Universidad Católica San Antonio de Murcia (UCAM), Rambam Health Care Campus [Haifa, Israel], Technion - Israel Institute of Technology [Haifa], Ministry of Health of the Russian Federation (MHRF), St James's University Hospital, Leeds Teaching Hospitals NHS Trust, Trinity College Dublin, National and Kapodistrian University of Athens (NKUA), McMaster University [Hamilton, Ontario], Firestone Institute for Respiratory Health [Hamilton, ON, Canada] (FIRH), Ministry of Health [Saudi Arabia], Szent Imre Hospital [Budapest, Hungary] (SIH), Mashhad University of Medical Sciences, University of Edinburgh, Capital University of Medical Sciences [Beijing] (CUMS), Hôpitaux Universitaires de l'Est Parisien [Paris] (HUEP), Monash Medical Centre [Clayton, Australia], Central University of Tamil Nadu [Thiruvarur, India] (CUTN), Central University of Tamil Nadu (CUTN), Okmeydani Training and Research Hospital [Istanbul, Turkey] (OTRH), Centre International de Cancérologie de Dakar [Dakar, Senegal] (CICD), Aristotle University of Thessaloniki, University Hospital Southampton NHS Foundation Trust, Université Virtuelle du Sénégal [Dakar, Senegal] (UVS), Innovations thérapeutiques en hémostase (IThEM - U1140), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), University Clinic of Hematology [Skopje, Republic of North Macedonia] (UCH), University of Medicine and Pharmacy [Cluj-Napoca, Romania] (UMP), Service d'Anesthésie réanimation [CHU Tenon], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Flor Ferenc Teaching Hospital [Kistarcsa, Hungary] (2FTH), San Camillo Forlanini Hospital [Rome], Loyola University Medical Center (LUMC), Science Valley Research Institute [São Paulo, Brazil] (SVRI), King Hussein Cancer Center [Amman, Jordan] (KH2C), CHU Fattouma Bourguiba [Monastir] (HFB), Medizinische Universität Wien = Medical University of Vienna, Nobelpharma Co. Ltd. [Tokyo, Japan], Hôpital Erasme [Bruxelles] (ULB), Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), North Shore University Cardiologists [Skokie, Illinois, USA] (NSUC), American University of Beirut Faculty of Medicine and Medical Center (AUB), Klinikum Ernst von Bergmann [Potsdam, Germany] (KEVB), Peking University [Beijing], Chinese Academy of Medical Sciences [Beijing, China] (CAMS), Peking Union Medical College [Beijing, China], Université Mohammed V de Rabat [Agdal] (UM5), Scientific Reviewer Committee: Gregory Y H Lip, Michael Makris, Sam Schulman, Wolfgang Siess, Christian Weber, Sabbah, Michèle, Centre de Recherche Saint-Antoine (CR Saint-Antoine), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Saint-Antoine [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), University of Milan, Centre d'Immunologie et de Maladies Infectieuses (CIMI), Università degli Studi di Milano-Bicocca [Milano] (UNIMIB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and University of Mohammed V
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medicine.medical_specialty ,Telemedicine ,Economic growth ,COVID-19 Vaccines ,Population ,Psychological intervention ,Disease ,030204 cardiovascular system & hematology ,Risk Assessment ,Herd immunity ,03 medical and health sciences ,COVID-19 Testing ,0302 clinical medicine ,Consensus Paper ,Pandemic ,medicine ,[SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology ,Humans ,[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology ,030212 general & internal medicine ,Disease management (health) ,education ,Pandemics ,thrombosis ,education.field_of_study ,SARS-CoV-2 ,Immunization Programs ,pandemic ,Public health ,COVID-19 ,Disease Management ,health care systems ,Hematology ,3. Good health ,Public Health ,Business - Abstract
Background One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the implementation of mandatory physical barriers and social distancing, humanity remains challenged by a long-lasting and devastating public health crisis. Management Non-pharmacological interventions (NPIs) are efficient mitigation strategies. The success of these NPIs is dependent on the approval and commitment of the population. The launch of a mass vaccination program in many countries in late December 2020 with mRNA vaccines, adenovirus-based vaccines, and inactivated virus vaccines has generated hope for the end of the pandemic. Current Issues The continuous appearance of new pathogenic viral strains and the ability of vaccines to prevent infection and transmission raise important concerns as we try to achieve community immunity against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and its variants. The need of a second and even third generation of vaccines has already been acknowledged by the WHO and governments. Perspectives There is a critical and urgent need for a balanced and integrated strategy for the management of the COVID-19 outbreaks organized on three axes: (1) Prevention of the SARS-CoV-2 infection, (2) Detection and early diagnosis of patients at risk of disease worsening, and (3) Anticipation of medical care (PDA). Conclusion The “PDA strategy” integrated into state policy for the support and expansion of health systems and introduction of digital organizations (i.e., telemedicine, e-Health, artificial intelligence, and machine-learning technology) is of major importance for the preservation of citizens' health and life world-wide.
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- 2021
29. Ensuring continuity of care by small family practices and clinics in the primary care setting during COVID 19 pandemic 2020 - A position paper by the Academy of Family Physicians of India
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Resmi S Kaimal, Vandana Boobna, Raman Kumar, Sreenivas Venkapalli, Mohan Kubendra, and Jachin Velavan
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medicine.medical_specialty ,Isolation (health care) ,Coronavirus disease 2019 (COVID-19) ,lcsh:Medicine ,030209 endocrinology & metabolism ,Primary care ,law.invention ,03 medical and health sciences ,primary care ,0302 clinical medicine ,law ,Pandemic ,Medicine ,academy of family physicians of india ,030212 general & internal medicine ,Obligation ,business.industry ,lcsh:R ,family physicians ,Family medicine ,CLARITY ,Position paper ,Continuity of care ,Position Paper ,covid 19 in india ,business - Abstract
The world is passing through a global pandemic of COVID 19. The number of positive cases has crossed over twenty thousand as of April 2020. Like everyone else, it is indeed a very challenging situation for family physicians and primary care providers as most of the guidelines presently have focused on screening, quarantine, isolation, and hospital-based management. Limited information or clarity is available on running small private clinics during pandemic times. The key concern is professional obligation versus risks of community transmission. Family physicians see routine flu-like illnesses throughout the year with seasonal variation within their practices. This document is intended to develop consensus and standard practices for the family physicians and other primary care providers during the pandemic, ensuring optimal continuity of care. This document was reviewed by the national executive of the Academy of Family Physicians of India and approved for dissemination among members. However, due to the dynamic status of the pandemic, all practitioners are advised to closely follow the instructions, guidelines, and advisories of national, state and local health authorities as well.
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- 2020
30. Short Research Paper: Personal protective equipment for the care of suspected and confirmed COVID-19 patients - modelling requirements and burn rate
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Andrew W. Kam, Nicole King, Nicole Phillips, Ashima Sharma, Vineet Nayyar, and Ramon Z. Shaban
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medicine.medical_specialty ,Infectious Disease Transmission, Patient-to-Professional ,Coronavirus disease 2019 (COVID-19) ,Referral ,simulation modelling ,Audit ,030501 epidemiology ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,law ,Intensive care ,Patient-Centered Care ,Pandemic ,Medicine ,Humans ,030212 general & internal medicine ,Personal protective equipment ,General Nursing ,business.industry ,Simulation modelling ,Public Health, Environmental and Occupational Health ,COVID-19 ,Intensive care unit ,ICU, intensive care unit ,Hospitals ,Coronavirus ,Infectious Diseases ,Emergency medicine ,personal protective equipment ,New South Wales ,0305 other medical science ,business ,95%CI, 95% confidence interval ,PPE, personal protective equipment ,Research Paper - Abstract
Background The COVID-19 pandemic has caused unprecedented global demand for personal protective equipment (PPE). A paucity of data on PPE burn rate (PPE consumption over time) in pandemic situations exacerbated these issues as there was little historic research to indicate volumes of PPE required to care for surges in infective patients and thus plan procurement requirements. Methods To better understand PPE requirements for care of suspected or confirmed COVID-19 patients in our Australian quaternary referral hospital, the number of staff-to-patient interactions in a 24-h period for three patient groups (ward-based COVID suspect, ward-based COVID confirmed, intensive care COVID confirmed) was audited prospectively from 1st to 30th April 2020. Results The average number of staff-to-patient interactions in a 24-h period was: 13.1 ± 5.0 (mean ± SD) for stable ward-managed COVID-19 suspect patients; 11.9 ± 3.8 for stable ward-managed confirmed COVID-19 patients; and 30.0 ± 5.3 for stable, mechanically ventilated, ICU-managed COVID-19 patients. This data can be used in PPE demand simulation modelling for COVID-19 and potentially other respiratory illnesses. Conclusion Data on the average number of staff-to-patient interactions needed for the care of COVID-19 patients is presented. This data can be used for PPE demand simulation modelling.
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- 2021
31. Preparing for a future crisis: using DEA-based performance analysis to assess initial pandemic responses in the Taiwanese hotel industry
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Huang, Yu-Hsiang (John), Meyer, Bradley, Connolly, Daniel, and Strader, Troy
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- 2024
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32. EASL position paper on the use of COVID-19 vaccines in patients with chronic liver diseases, hepatobiliary cancer and liver transplant recipients
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Markus Cornberg, Maria Buti, Daniel Shouval, Paolo Grossi, Christiane S. Eberhardt, and CiiM, Zentrum für individualisierte Infektionsmedizin, Feodor-Lynen-Str.7, 30625 Hannover.
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medicine.medical_specialty ,COVID-19 Vaccines ,Cirrhosis ,Coronavirus disease 2019 (COVID-19) ,medicine.medical_treatment ,Liver transplantation ,Immunocompromised Host ,Pandemic ,Humans ,Medicine ,Intensive care medicine ,Letter to the Editor ,Hepatology ,business.industry ,SARS-CoV-2 ,Liver Diseases ,Immunogenicity ,Vaccination ,COVID-19 ,medicine.disease ,Influenza ,Clinical trial ,Biliary Tract Neoplasms ,Position paper ,Risk Adjustment ,business ,Vaccine ,Liver Transplantation - Abstract
According to a recent World Health Organization estimate, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, which originated in China in 2019, has spread globally, infecting nearly 100 million people worldwide by January 2021. Patients with chronic liver diseases (CLD), particularly cirrhosis, hepatobiliary malignancies, candidates for liver transplantation, and immunosuppressed individuals after liver transplantation appear to be at increased risk of infections in general, which in turn translates into increased mortality. This is also the case for SARS-CoV-2 infection, where patients with cirrhosis, in particular, are at high risk of a severe COVID-19 course. Therefore, vaccination against various pathogens including SARS-CoV-2, administered as early as possible in patients with CLD, is an important protective measure. However, due to impaired immune responses in these patients, the immediate and long-term protective response through immunisation may be incomplete. The current SARS-CoV-2 pandemic has led to the exceptionally fast development of several vaccine candidates. A small number of these SARS-CoV-2 vaccine candidates have already undergone phase III, placebo-controlled, clinical trials in healthy individuals with proof of short-term safety, immunogenicity and efficacy. However, although regulatory agencies in the US and Europe have already approved some of these vaccines for clinical use, information on immunogenicity, duration of protection and long-term safety in patients with CLD, cirrhosis, hepatobiliary cancer and liver transplant recipients has yet to be generated. This review summarises the data on vaccine safety, immunogenicity, and efficacy in this patient population in general and discusses the implications of this knowledge on the introduction of the new SARS-CoV-2 vaccines.
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- 2021
33. COVID-19 FAQs in paediatric and congenital cardiology: AEPC position paper
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Ornella Milanesi, Skaiste Sendzikaite, Ruth Heying, Katarina Hanséus, and Ina Michel-Behnke
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medicine.medical_specialty ,2019-20 coronavirus outbreak ,Battle ,Coronavirus disease 2019 (COVID-19) ,media_common.quotation_subject ,Review ,030204 cardiovascular system & hematology ,General Cardiology ,AEPC ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Health care ,Pandemic ,medicine ,Humans ,Prostaglandins I ,030212 general & internal medicine ,Pediatrics, Perinatology, and Child Health ,Child ,media_common ,multisystem inflammatory syndrome ,SARS-CoV-2 ,business.industry ,Frequently asked questions ,COVID-19 ,General Medicine ,congenital heart disease ,Epoprostenol ,Kawasaki ,SARS-Cov-2 ,Paediatric cardiology ,Pediatrics, Perinatology and Child Health ,Cardiology ,Position paper ,Endothelium, Vascular ,business ,Cardiology and Cardiovascular Medicine - Abstract
The COVID-19 pandemic has had a huge influence in almost all areas of life, affecting societies, economics, and health care systems worldwide. The paediatric cardiology community is no exception. As the challenging battle with COVID-19 continues, professionals from the Association for the European Paediatric and Congenital Cardiology receive many questions regarding COVID-19 in a Paediatric and Congenital Cardiology setting. The aim of this paper is to present the AEPC position on frequently asked questions based on the most recent scientific data, as well as to frame a discussion on how to take care of our patients during this unprecedented crisis. As the times are changing quickly and information regarding COVID-19 is very dynamic, continuous collection of evidence will help guide constructive decision-making.
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- 2021
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34. Impact of COVID-19 on the care of patients with liver disease: EASL-ESCMID position paper after 6 months of the pandemic
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Mario U. Mondelli, Elisa Cordero, Philip N. Newsome, Mojca Maticic, Richard Moreau, Thomas Berg, Rajiv Jalan, Markus Cornberg, Tobias Boettler, Thomas Marjot, National Institutes of Health (US), National Health Service (UK), Boettler, Tobias [0000-0002-1195-055X], Maticic, Mojca [0000-0003-4261-0424], Cordero, Elisa [0000-0001-7766-7266], Moreau, Richard [0000-0003-0862-403X], Boettler, Tobias, Maticic, Mojca, Cordero, Elisa, and Moreau, Richard
- Subjects
upper limit of normal ,Cirrhosis ,Upper limit of normal ,Hepatocellular carcinoma ,ALT ,Metabolic-dysfunction associated fatty liver disease ,ACE2 ,ULN ,Chronic liver disease ,Esophagogastroduodenoscopy ,Liver disease ,Model for End-Stage Liver Disease ,aspartate aminotransferase ,ACLF ,Pandemic ,ACE-I ,Severe acute respiratory syndrome coronavirus 2 ,Immunology and Allergy ,model for end-stage liver disease ,HCC ,Non-alcoholic steatohepatitis ,nucleoside analogue ,Cancer ,Model for end-stage liver disease ,Coronavirus disease 2019 ,NASH ,Gastroenterology ,ERC ,hepatocellular carcinoma ,Angiotensin-converting enzyme 2 ,Nucleoside analogue ,Telemedicine ,Acute-on-chronic liver failure ,angiotensin-converting enzyme inhibitor ,Liver ,non-alcoholic steatohepatitis ,acute-on-chronic liver failure ,severe acute respiratory syndrome coronavirus 2 ,medicine.medical_specialty ,Endoscopic retrograde cholangiography ,alanine aminotransferase ,esophagogastroduodenoscopy ,MAFLD ,Aspartate aminotransferase ,Article ,coronavirus disease 2019 ,angiotensin-converting enzyme 2 ,NAFLD ,NUC ,Internal Medicine ,medicine ,lcsh:RC799-869 ,Intensive care medicine ,AST ,EGD ,Hepatology ,SARS-CoV-2 ,business.industry ,COVID-19 ,endoscopic retrograde cholangiography ,medicine.disease ,MELD ,Transplantation ,Angiotensin-converting enzyme inhibitor ,Alanine aminotransferase ,Position paper ,lcsh:Diseases of the digestive system. Gastroenterology ,business - Abstract
During the early stages of the COVID-19 pandemic, EASL and ESCMID published a position paper to provide guidance for physicians involved in the care of patients with chronic liver disease. In the meantime, many countries and healthcare systems have been, or are still overwhelmed by the pandemic, significantly impacting on the care of this group of patients, whilst others have started to return towards their usual routine. In addition, many studies have been published focusing on how COVID-19 may affect the liver and how pre-existing liver diseases might influence the clinical course of COVID-19. While many aspects remain poorly understood, it has become increasingly evident that pre-existing liver diseases and liver injury during the course of the disease have to be kept in mind when caring for patients with COVID-19. Thus, this review should serve as an update on the previous position paper summarizing the evidence for liver disease involvement during COVID-19 and also provid, PNN was supported by the National Institute of Health Research (NIHR) Birmingham Biomedical Research Centre (BRC). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.
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- 2020
35. Strategies for Managing the Impacts of Disruptions During COVID-19: an Example of Toilet Paper
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Priyabrata Chowdhury and Sanjoy Kumar Paul
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2019-20 coronavirus outbreak ,High-demand items ,021103 operations research ,Pandemic ,Coronavirus disease 2019 (COVID-19) ,Supply chain disruptions ,Strategy and Management ,Supply chain ,05 social sciences ,0211 other engineering and technologies ,COVID-19 ,02 engineering and technology ,Profit (economics) ,Management Information Systems ,Risk analysis (engineering) ,Service level ,0502 economics and business ,Toilet paper ,Business ,Strategies ,Business and International Management ,Social responsibility ,050203 business & management ,Original Research - Abstract
Due to the recent pandemic of coronavirus, known as the COVID-19 outbreak, the supply chains have been impacted most significantly. Manufacturers of certain items have experienced a substantial increase in demand, and on the other hand, raw materials supply, to produce those items, has reduced because of supply failure. To overcome these challenges, this paper proposes some strategies to improve service level during an extraordinary pandemic outbreak, such as COVID-19, for the most wanted products such as toilet paper. This study considers meeting the increased demand of the customers for an essential product of daily life like toilet paper during a pandemic is beyond the traditional economic objective, i.e., increase profit, of the manufacturers. Instead, this should be more about the social responsibility of all the manufactures to ensure that they can serve more customers. Motivated by this and taking toilet paper as an example of the product, we first analyzed the current scenario of the manufacturing and the demand for the product and then proposed some strategies to deal with this unprecedented risk and analyzed the results. We have compared the results, using hypothetical data, between the current scenario and proposed strategies. The result shows that sharing information and resources from all manufacturers to produce under a single brand, emergency sourcing, producing basic quality items, and packing in the smallest sizes have a significant positive impact on the service level. This paper first investigates the strategies for a high-demand and essential item during a pandemic situation and proposes strategies to deal with this unique, extraordinary disruption.
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- 2020
36. Leadership learning during a pandemic: reflections in a time of crisis
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Vaughn, Laura, Beatty, Cameron C., and Ostermeyer, Emily
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- 2024
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37. Impact of private and public initiatives on individuals' employment and income during the COVID-19 pandemic: evidence from Peru
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Mongrut, Samuel Arturo, Cruz, Vivian, and Pacussich, Daniela
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- 2024
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38. COVID-19 and the decline of active social media engagement
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Poole, Maxwell, Pancer, Ethan, Philp, Matthew, and Noseworthy, Theodore J.
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- 2024
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39. Exercise Mataika: White Paper on response to a smallpox bioterrorism release in the Pacific
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William D. Rawlinson, Michael G Baker, John Michael Lane, Jesper Elsgaard, Devina Nand, Lauasa Fotualii, Kevin Yeo, Michael Butel, Tomasz Kiedrzynski, Cassidy Nelson, David J Heslop, Alexander Rosewell, Chandini Raina MacIntyre, Louise Fonua, and Craig Schramm
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Smallpox, orthopoxviruses, pandemic, epidemic, military, police, public health, disaster, first responder, health security, bioterrorism, terrorism, warfare, biological select agents, synthetic biology ,medicine.medical_specialty ,business.industry ,Public health ,lcsh:Public aspects of medicine ,Law enforcement ,Legislation ,lcsh:RA1-1270 ,Public relations ,medicine.disease ,lcsh:Infectious and parasitic diseases ,First responder ,public health, disaster response, infectious diseases, terrorism, warfare, biowarfare, bioterrorism ,White paper ,Political science ,Preparedness ,Pandemic ,medicine ,Smallpox ,lcsh:RC109-216 ,business - Abstract
Smallpox was declared eradicated in 1980, with known seed stock retained in two high security Biosafety Level 4 laboratories in the United States and Russia. Experts agree the likelihood of theft from these laboratories is low, and that synthetic creation of smallpox is a theoretical possibility. Until 2017 it was believed that synthetic smallpox was technically too complex a task to be a serious threat. However, in 2017, Canadian scientists synthesised a closely related orthopoxvirus, horsepox, using mail order DNA and $100,000. Simultaneously, terrorist groups have declared intent to conduct biological attacks. In this context an exercise was held on August 16th 2018, with international and cross-sectoral stakeholders to review preparedness for a bioterrorism attack in the Asia-Pacific region and globally. The exercise was conducted by The National Health and Medical Research Council (NHMRC) Centre for Research Excellence, Integrated Systems for Epidemic Response, with contextual input from the Ministry of Health and Medical Services Fiji. The scenario involved a deliberate release in Fiji, followed by a larger release in a more populous Asian country. Mathematical modelling was used to underpin epidemic projections under different conditions. The exercise alternated between clinical, public health, emergency and societal responses, with participants making real-time decisions on cross-sectoral response across the region and the world. Key weak points which are influential in determining the final size and impact of the epidemic were identified (based on mathematical modelling of transmission in Fiji and globally). We identified potential gaps in preparedness for smallpox and factors which influence the severity of a smallpox epidemic. This included identifying which determinants of epidemic size are potentially within our control, and which are not. Influential factors within our control include: preventing an attack through intelligence, law enforcement and legislation; speed of diagnosis; speed and completeness of case finding and case isolation; speed and security of vaccination response, including stockpiling; speed and completeness of contact tracing; protecting critical infrastructure and business continuity; non-pharmaceutical interventions (social distancing, PPE, border control); protecting first responders; operational support and logistics; social mobilisation and risk communication. Based on discussion at the workshop between diverse stakeholders, recommendations were made to guide improved prevention, mitigation and rapid response, thus providing a holistic, cross-sectoral framework for prevention of a worst-case scenario smallpox pandemic.
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- 2019
40. Cardiovascular RNA markers and artificial intelligence may improve COVID-19 outcome: a position paper from the EU-CardioRNA COST Action CA17129
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Kanita Karaduzovic-Hadziabdic, Reinhard Schneider, Péter Ferdinandy, Venkata P. Satagopam, Yvan Devaux, Eric Nham, Irina Carpusca, Ines Potočnjak, Mitja Luštrek, Costanza Emanueli, Wei Gu, Thomas Thum, Leon J deWindt, Amela Jusic, Matthias Hackl, Fabio Martelli, Emma L. Robinson, Lina Badimon, Mariann Gyöngyösi, Luxembourg Centre for Systems Biomedicine (LCSB): Bioinformatics Core (R. Schneider Group) [research center], and Publica
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0301 basic medicine ,Artificial intelligence ,Physiology ,Disease ,Review ,030204 cardiovascular system & hematology ,Biochemistry, biophysics & molecular biology [F05] [Life sciences] ,CARDIOLOGY WORKING GROUP ,Cardiovascular System ,CARDIOPROTECTION ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Physiology (medical) ,CELLULAR BIOLOGY ,INFECTION ,Health care ,Pandemic ,genomics ,IMMUNE-RESPONSE ,Medicine ,Humans ,AcademicSubjects/MED00200 ,Biochimie, biophysique & biologie moléculaire [F05] [Sciences du vivant] ,business.industry ,SARS-CoV-2 ,RNA ,COVID-19 ,biomarkers ,ASSOCIATION ,Genomics ,medicine.disease ,artificial intelligence ,EUROPEAN-SOCIETY ,RNAs ,SEVERITY ,030104 developmental biology ,Cardiovascular Diseases ,Heart failure ,Quality of Life ,HEART-FAILURE ,Biomarker (medicine) ,Position paper ,Cardiology and Cardiovascular Medicine ,business ,Biomarkers - Abstract
The coronavirus disease 2019 (COVID-19) pandemic has been as unprecedented as unexpected, affecting more than 105 million people worldwide as of 8 February 2020 and causing more than 2.3 million deaths according to the World Health Organization (WHO). Not only affecting the lungs but also provoking acute respiratory distress, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is able to infect multiple cell types including cardiac and vascular cells. Hence a significant proportion of infected patients develop cardiac events, such as arrhythmias and heart failure. Patients with cardiovascular comorbidities are at highest risk of cardiac death. To face the pandemic and limit its burden, health authorities have launched several fast-track calls for research projects aiming to develop rapid strategies to combat the disease, as well as longer-term projects to prepare for the future. Biomarkers have the possibility to aid in clinical decision-making and tailoring healthcare in order to improve patient quality of life. The biomarker potential of circulating RNAs has been recognized in several disease conditions, including cardiovascular disease. RNA biomarkers may be useful in the current COVID-19 situation. The discovery, validation, and marketing of novel biomarkers, including RNA biomarkers, require multi-centre studies by large and interdisciplinary collaborative networks, involving both the academia and the industry. Here, members of the EU-CardioRNA COST Action CA17129 summarize the current knowledge about the strain that COVID-19 places on the cardiovascular system and discuss how RNA biomarkers can aid to limit this burden. They present the benefits and challenges of the discovery of novel RNA biomarkers, the need for networking efforts, and the added value of artificial intelligence to achieve reliable advances.
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- 2021
41. Therapeutic strategies for severe COVID-19: a position paper from the Italian Society of Infectious and Tropical Diseases (SIMIT)
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Silvia Nozza, Cristina Mussini, Giampiero Carosi, Antonio Cascio, Francesco Mazzotta, Nicola Petrosillo, Marco Falcone, Roberto Parrella, Paolo Grossi, Antonio Chirianni, Carmelo Iacobello, Evangelista Sagnelli, Claudio Maria Mastroianni, Massimo Galli, Marco Tinelli, Marianna Meschiari, Marcello Tavio, Massimo Andreoni, Giovanni Di Perri, V. Portelli, Chiara Iaria, Orlando Armignacco, Caterina Sagnelli, Mussini, C., Falcone, M., Nozza, S., Sagnelli, C., Parrella, R., Meschiari, M., Petrosillo, N., Mastroianni, C., Cascio, A., Iaria, C., Galli, M., Chirianni, A., Sagnelli, E., Iacobello, C., Di Perri, G., Mazzotta, F., Carosi, G., Tinelli, M., Grossi, P., Armignacco, O., Portelli, V., Andreoni, M., Tavio, M., Mussini C., Falcone M., Nozza S., Sagnelli C., Parrella R., Meschiari M., Petrosillo N., Mastroianni C., Cascio A., Iaria C., Galli M., Chirianni A., Sagnelli E., Iacobello C., Di Perri G., Mazzotta F., Carosi G., Tinelli M., Grossi P., Armignacco O., Portelli V., Andreoni M., and Tavio M.
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0301 basic medicine ,Microbiology (medical) ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,030106 microbiology ,Coronaviru ,practice guidelines as topic ,coronavirus ,randomized controlled trials as topic ,Guidelines ,medicine.disease_cause ,medical ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,societies ,Randomized controlled trial ,law ,Pandemic ,italy ,medicine ,pneumonia ,030212 general & internal medicine ,Intensive care medicine ,humans ,Societies, Medical ,Coronavirus ,therapy ,SARS-CoV-2 ,business.industry ,COVID-19 ,Pneumonia ,Therapy ,Standard treatment ,General Medicine ,covid-19 ,sars-cov-2 ,societies, medical ,standard of care ,COVID-19 Drug Treatment ,Clinical trial ,Infectious Diseases ,Position paper ,Observational study ,business ,Human - Abstract
Scope Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become pandemic, reaching almost one million death worldwide. At present standard treatment for coronavirus disease 2019 (COVID-19) is not well defined because the evidence, either from randomized or observational studies, with conflicting results, has led to rapid changes in treatment guidelines. Our aim was to narratively summarize the available literature on the management of COVID-19 in order to combine current evidence and interpretation of the data by experts who are treating patients in the frontline setting. Methods The panel conducted a detailed review of the literature and eventual press releases from randomized clinical trials for each possible available treatment. Inductive PubMed search waws performed for publications relevant to the topic, including all clinical trials conducted. The result was a flowchart with treatment indications for patients with COVID-19. Implications After 6 months of a pandemic situation and before a possible second coronavirus wave descends on Europe, it is important to evaluate which drugs proved to be effective while also considering that results from many randomized clinical trials are still awaited. Indeed, among treatments for COVID-19, only glucocorticoids have resulted in an association with a significant decrease in mortality in published randomized controlled trials. New therapeutic strategies are urgently needed.
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- 2021
42. Israeli Position Paper
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Ephrat Levy-Lahad, Charles L. Sprung, Tami Karni, and Avraham Steinberg
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Pulmonary and Respiratory Medicine ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Bioethics ,medicine.disease ,Critical Care and Intensive Care Medicine ,Triage ,Pandemic ,Position paper ,Medicine ,Medical emergency ,business ,Cardiology and Cardiovascular Medicine ,Health policy - Published
- 2020
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43. Paper-based record file of patients could be a fomite for SARS- CoV-2 transmission in Hospital Setting of Low- and Middle-Income Countries (LMICs)
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Yadav, Dipak Kumar, Shah, Pushpa Kumari, and Enyoh, Christian Ebere
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Paper ,Pandemic ,COVID-19 ,Transmission - Abstract
In the wake of the present COVID-19 pandemic, there has been a much-needed increase in awareness among the general public of handwashing, social distancing, and observing cough and sneeze etiquette, and even disinfecting other fomites, we miss to focus on the paper documents, which has been the method and in some low and middle economy countries (LMICs), ‘the only method’ of patients documentation. Worthy of note is that the virus can survive on paper and on cardboard for up to 3 to 24 hours. Most of the hospitals in LMICs are using paper to keep patient records, owing to poor funding and lack of proper databases. Each record file is exchanged many times between health care workers, patient’s caretakers as well as various administrative people in the hospital; also it travels to different wards or rooms for various purposes along with patients during the course of medical check-up and treatment. The virus could be transmitted during this process. At present, very little is known regarding surface distribution of SARS-CoV-2 in hospitals of LMICs which rely on paper documentation of patients. This paper raises the question regarding the risk of using paper-based record keeping inside hospitals during the COVID-19 pandemic.
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- 2020
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44. Current perspectives on coronavirus disease 2019 and cardiovascular disease: a white paper by the JAHA editors
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Jose Gutierrez, Daniel Addison, Hossein Ardehali, Holli A. DeVon, Carmela Maniero, Reynaldo Sanchez, Hani Jneid, Ajay Gupta, Vikas Kapil, Pamela S. Miller, Nicolas Delarche, Carol Ann Remme, Jai D. Parekh, Amgad Mentias, Anneline S.J.M. te Riele, Romain Boulestreau, Sher May Ng, Konrad T Sawicki, Barry London, Sanket Borgaonkar, Amelia K. Boehme, Kevin J. Clerkin, Isabella M. Grumbach, and Daniel A. Jones
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cardiovascular risk factors ,Cardiac & Cardiovascular Systems ,Epidemiology ,White Paper ,Disease ,Comorbidity ,Cardiorespiratory Medicine and Haematology ,Global Health ,ACUTE CORONARY SYNDROME ,THERAPY ,SARS‐CoV‐2 ,White paper ,RESPIRATORY SYNDROME ,Risk Factors ,cardiovascular disease ,Health care ,Pandemic ,Global health ,Viral ,1102 Cardiorespiratory Medicine and Haematology ,treatment ,Incidence (epidemiology) ,Incidence ,INVASIVE STRATEGY ,C-REACTIVE PROTEIN ,Cardiovascular Diseases ,Cardiology and Cardiovascular Medicine ,Coronavirus Infections ,Life Sciences & Biomedicine ,management ,medicine.medical_specialty ,ACUTE MYOCARDIAL-INFARCTION ,Coronavirus disease 2019 (COVID-19) ,Pneumonia, Viral ,AMERICAN-COLLEGE ,EXTRACORPOREAL MEMBRANE-OXYGENATION ,coronavirus disease 2019 ,Betacoronavirus ,COVID‐19 ,medicine ,Humans ,ASSOCIATION TASK-FORCE ,Intensive care medicine ,Pandemics ,Science & Technology ,business.industry ,SARS-CoV-2 ,COVID-19 ,Pneumonia ,medicine.disease ,White Papers ,Cardiovascular System & Cardiology ,business - Abstract
Coronavirus Disease 2019 (COVID‐19) has infected more than 3.0 million people worldwide and killed more than 200,000 as of April 27, 2020. In this White Paper, we address the cardiovascular co‐morbidities of COVID‐19 infection; the diagnosis and treatment of standard cardiovascular conditions during the pandemic; and the diagnosis and treatment of the cardiovascular consequences of COVID‐19 infection. In addition, we will also address various issues related to the safety of healthcare workers and the ethical issues related to patient care in this pandemic.
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- 2020
45. Telemedicine Across the Globe-Position Paper From the COVID-19 Pandemic Health System Resilience PROGRAM (REPROGRAM) International Consortium (Part 1)
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Sonu Bhaskar, Sian Bradley, Vijay Kumar Chattu, Anil Adisesh, Alma Nurtazina, Saltanat Kyrykbayeva, Sateesh Sakhamuri, Sanni Yaya, Thankam Sunil, Pravin Thomas, Viviana Mucci, Sebastian Moguilner, Simon Israel-Korn, Jason Alacapa, Abha Mishra, Shawna Pandya, Starr Schroeder, Ashish Atreja, Maciej Banach, and Daniel Ray
- Subjects
medicine.medical_specialty ,Telemedicine ,telehealth ,Interoperability ,Telehealth ,03 medical and health sciences ,0302 clinical medicine ,geographics ,framework ,Pandemic ,medicine ,Humans ,030212 general & internal medicine ,Pandemics ,Health policy ,digital technologies ,business.industry ,SARS-CoV-2 ,030503 health policy & services ,Public health ,lcsh:Public aspects of medicine ,Public Health, Environmental and Occupational Health ,COVID-19 ,health policy ,lcsh:RA1-1270 ,Public relations ,Resilience (organizational) ,Policy Brief ,Position paper ,Business ,Public Health ,telemedicine ,0305 other medical science ,recommendations (guidelines) - Abstract
Coronavirus disease 2019 (COVID-19) has accelerated the adoption of telemedicine globally. The current consortium critically examines the telemedicine frameworks, identifies gaps in its implementation and investigates the changes in telemedicine framework/s during COVID-19 across the globe. Streamlining of global public health preparedness framework that is interoperable and allow for collaboration and sharing of resources, in which telemedicine is an integral part of the public health response during outbreaks such as COVID-19, should be pursued. With adequate reinforcement, telemedicine has the potential to act as the "safety-net" of our public health response to an outbreak. Our focus on telemedicine must shift to the developing and under-developing nations, which carry a disproportionate burden of vulnerable communities who are at risk due to COVID-19.
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- 2020
46. Management of paediatric IBD after the peak of COVID-19 pandemic in Italy: A position paper on behalf of the SIGENP IBD working group
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Federica Mario, Federica Nuti, Chiara Moretti, Claudia Banzato, Lorenzo Norsa, Stefano Martelossi, Claudio Romano, Caterina Strisciuglio, Sara Renzo, Antonio Corsello, Maurizio Fuoti, Massimo Martinelli, Anna Dilillo, Zeno Giusti, Paolo Lionetti, Simona Gatti, Valeria Dipasquale, Fortunata Civitelli, Erminia Romeo, A. Marseglia, Enrico Felici, Matteo Bramuzzo, Roberto Panceri, Stefania Rampado, Serena Arrigo, Patrizia Alvisi, Daniela Knafelz, Giulia D'Arcangelo, Arrigo, Serena, Alvisi, Patrizia, Banzato, Claudia, Bramuzzo, Matteo, Civitelli, Fortunata, Corsello, Antonio, D'Arcangelo, Giulia, Dilillo, Anna, Dipasquale, Valeria, Felici, Enrico, Fuoti, Maurizio, Gatti, Simona, Giusti, Zeno, Knafelz, Daniela, Lionetti, Paolo, Mario, Federica, Marseglia, Antonio, Martelossi, Stefano, Moretti, Chiara, Norsa, Lorenzo, Nuti, Federica, Panceri, Roberto, Rampado, Stefania, Renzo, Sara, Romano, Claudio, Romeo, Erminia, Strisciuglio, Caterina, Martinelli, Massimo, Arrigo, S., Alvisi, P., Banzato, C., Bramuzzo, M., Civitelli, F., Corsello, A., D'Arcangelo, G., Dilillo, A., Dipasquale, V., Felici, E., Fuoti, M., Gatti, S., Giusti, Z., Knafelz, D., Lionetti, P., Mario, F., Marseglia, A., Martelossi, S., Moretti, C., Norsa, L., Nuti, F., Panceri, R., Rampado, S., Renzo, S., Romano, C., Romeo, E., Strisciuglio, C., and Martinelli, M.
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2019-20 coronavirus outbreak ,medicine.medical_specialty ,COVID-19, Inflammatory bowel disease, Paediatrics ,SARS-CoV2 ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Guidelines ,Inflammatory bowel disease ,Pediatrics ,Disease course ,03 medical and health sciences ,0302 clinical medicine ,Pandemic ,Medicine ,Humans ,Intensive care medicine ,Child ,Hepatology ,business.industry ,SARS-CoV-2 ,Gastroenterology ,Outbreak ,COVID-19 ,Paediatrics ,medicine.disease ,Inflammatory Bowel Diseases ,Organizational Innovation ,Italy ,Paediatric ,030220 oncology & carcinogenesis ,Communicable Disease Control ,Position paper ,030211 gastroenterology & hepatology ,Risk Adjustment ,business ,Human - Abstract
Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2, spreading in Italy during the first months of 2020, abruptly changed the way of practicing medicine in this country. As a consequence of the lockdown, the diagnostic and therapeutic management of paediatric chronic conditions, such as inflammatory bowel disease (IBD) has been affected. During the peak of COVID-19 pandemic, elective visits, endoscopies and infusions have been postponed, with potential clinical and psychological impact on disease course and a high likelihood of increasing waiting lists. While slowly moving back towards normality, clinicians need to recognize the best ways to care for patients with IBD, carefully avoiding risk factors for new potential epidemic outbreaks. In this uncertain scenario until the development and spread of COVID-19 vaccine, it is necessary to continue to operate with caution. Hereby we provide useful indications for a safer and gradual restarting of routine clinical activities after COVID-19 peak in Italy.
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- 2020
47. Treatment of children with COVID-19: position paper of the Italian Society of Pediatric Infectious Disease
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Elisabetta Venturini, Carlotta Montagnani, Silvia Garazzino, Daniele Donà, Luca Pierantoni, Andrea Lo Vecchio, Giangiacomo Nicolini, Sonia Bianchini, Andrzej Krzysztofiak, Luisa Galli, Alberto Villani, Guido Castelli-Gattinara, for the Italian SITIP-SIP SARS-Cov-2 pediatric infection study group, Venturini, E., Montagnani, C., Garazzino, S., Dona, D., Pierantoni, L., Lo Vecchio, A., Nicolini, G., Bianchini, S., Krzysztofiak, A., Galli, L., Villani, A., and Castelli-Gattinara, G.
- Subjects
medicine.medical_specialty ,2019-20 coronavirus outbreak ,Consensus ,Coronavirus disease 2019 (COVID-19) ,Adolescent ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Pneumonia, Viral ,SARS CoV-2 ,Consensu ,Review ,030204 cardiovascular system & hematology ,03 medical and health sciences ,Betacoronavirus ,0302 clinical medicine ,Children ,COVID-19 ,Treatment ,Pandemic ,medicine ,Humans ,Age Factor ,030212 general & internal medicine ,Child ,book ,Pandemics ,Societies, Medical ,Coronavirus Infection ,business.industry ,Maternal and child health ,SARS-CoV-2 ,Age Factors ,lcsh:RJ1-570 ,Infant ,lcsh:Pediatrics ,Settore MED/38 ,Italy ,Family medicine ,Child, Preschool ,Pediatric Infectious Disease ,book.journal ,Position paper ,Treatment strategy ,business ,Coronavirus Infections ,Human - Abstract
A statement of consensus was formulated after reviewing available literature on pediatric treatment strategies for COVID-19 by the Steering and Scientific Committee of the Italian Society of Infectious Pediatric Diseases in connection with the Italian Society of Paediatrics.
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- 2020
48. Physiotherapist Adaptations to Cancer, HIV/AIDS, and Hospice and Palliative Care in the COVID-19 Era: A Global Perspective Paper
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Jacqueline S. Drouin, Nnenna Nina Chigbo, and Ann H. Newstead
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Palliative care ,telehealth ,media_common.quotation_subject ,Physical Therapy, Sports Therapy and Rehabilitation ,Disease ,Telehealth ,evidence needs ,Promotion (rank) ,Nursing ,Acquired immunodeficiency syndrome (AIDS) ,equity in health care ,Perspective Paper ,Telerehabilitation ,Pandemic ,medicine ,critical thinking ,media_common ,Oncology(nursing) ,Oncology (nursing) ,business.industry ,Rehabilitation ,medicine.disease ,infection control ,Health equity ,Oncology ,business ,telerehabilitation - Abstract
In the early stages of the COVID-19 pandemic, physiotherapists (PTs) across the globe were required to rapidly adapt clinical practice to provide safe and effective care for people with HIV/AIDS and cancer and those in hospice and palliative care. These rapid decisions included developing criteria for in-person versus remote care and developing equitable platforms for telehealth and telerehabilitation. Most decisions were made with limited guidelines or evidence for practice related to the pandemic. The purpose of this perspective was to provide a synopsis of the experiences of 25 PTs from 16 countries regarding their clinical decisions for (1) rapid adaptation of patient care delivery, (2) evaluation criteria to treat in-person or remotely, (3) utilization decisions for telerehabilitation, (4) determinations for future practice and research needs, and (5) promotion of health equity in an environment rapidly transformed by a highly infectious and deadly disease.
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- 2020
49. ANMCO POSITION PAPER: The role of cardiology in the management of the health needs in the post-Covid-19 era
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Marino Scherillo, Stefano Urbinati, Loris Roncon, Adriano Murrone, Massimo Imazio, Stefano Domenicucci, Domenico Gabrielli, Manlio Cipriani, Giuseppina Maura Francese, Nadia Aspromonte, Giuseppe Di Pasquale, Vincenzo Amodeo, Michele Massimo Gulizia, Andrea Di Lenarda, Pasquale Caldarola, Furio Colivicchi, Fortunato Scotto di Uccio, and Serafina Valente
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Telemedicine ,Isolation (health care) ,Restructuring ,SARS-Cov-2 pandemic ,030204 cardiovascular system & hematology ,Phase (combat) ,03 medical and health sciences ,prescriptive appropriateness ,0302 clinical medicine ,Resource (project management) ,Multidisciplinary approach ,Pandemic ,Medicine ,AcademicSubjects/MED00200 ,cardiological outpatient activities ,cardiological inpatient activities ,business.industry ,territorial medicine ,Articles ,medicine.disease ,health needs ,cardiology ,Position paper ,Medical emergency ,telemedicine ,business ,Cardiology and Cardiovascular Medicine ,030217 neurology & neurosurgery - Abstract
At the end of 2019 a new Coronavirus appeared in China and, from there, it spread to the rest of the world On 24th May, 2020, the confirmed cases in the world were more than 5 million and the deaths almost 350 000 At the end of May, Italy reported more than 27 000 cases among healthcare professionals and 163 deaths among physicians The National Health Systems from almost all over the world, including Italy's, were unprepared for this pandemic, and this generated important consequences of organizational nature All elective and urgent specialized activities were completely reorganized, and many hospital units were partially or completely converted to the care of the COVID-19 patients A significant reduction in hospital admissions for acute heart disease were recorded during the SARS-CoV-2 pandemic and, in order to gradually resume hospital activities, the Italian National Phase 2 Plan for the partial recovery of activities, must necessarily be associated with a Phase 2 Health Plan In regards to the cardiac outpatient activities we need to identify short term goals, i e reschedule the suspended outpatient activities, revise the waiting lists, review the 'timings' of the bookings This will reduce the number of available examinations compared to the pre-Covid-19 era The GP's collaboration could represent an important resource, a structured telephone follow-up plan is advisable with the nursing staff's involvement It is equally important to set medium-long term goals, the pandemic could be an appropriate moment for making a virtue of necessity It is time to reason on prescriptive appropriateness, telemedicine implementation intended as integration to the traditional management It is time to restructure the cardiological units related to the issue of structural adjustment to the needs for functional isolation Moreover, the creation of 'grey zones' with multidisciplinary management according to the intensity of care levels seems to be necessary as well as the identification of Covid dedicated cardiologies Finally, the pandemic could represent the opportunity for a permanent renovation of the cardiological and territorial medicine activities © 2020 Oxford University Press All rights reserved
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- 2020
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50. Considerations for the management of home parenteral nutrition during the SARS-CoV-2 pandemic: A position paper from the Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of ESPEN
- Author
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Simon Lal, Geert J. A. Wanten, Federico Bozzetti, Manpreet S. Mundi, Cristina Cuerda, Carolyn Wheatley, Kinga Szczepanek, Georg Lamprecht, Francisca Joly, Michael Staun, Loris Pironi, André Van Gossum, Lal S., Van Gossum A., Joly F., Bozzetti F., Cuerda C., Lamprecht G., Mundi M.S., Staun M., Szczepanek K., Wanten G., Wheatley C., and Pironi L.
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0301 basic medicine ,medicine.medical_specialty ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Coronaviru ,Pneumonia, Viral ,030209 endocrinology & metabolism ,Clinical nutrition ,Critical Care and Intensive Care Medicine ,Article ,03 medical and health sciences ,Betacoronavirus ,0302 clinical medicine ,All institutes and research themes of the Radboud University Medical Center ,Ambulatory care ,Pandemic ,medicine ,Humans ,Intensive care medicine ,Pandemics ,Home parenteral nutrition ,Intestinal Disease ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Betacoronaviru ,Coronavirus Infection ,business.industry ,SARS-CoV-2 ,COVID-19 ,Chronic intestinal failure ,Special Interest Group ,Coronavirus ,Hospitalization ,Intestinal Diseases ,Parenteral nutrition ,lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] ,Chronic Disease ,Practice Guidelines as Topic ,Position paper ,business ,Coronavirus Infections ,Parenteral Nutrition, Home ,Human - Abstract
Summary The management of patients with chronic intestinal failure requiring home parenteral nutrition has been and will continue to be impaired during the SARS-CoV-2 pandemic. Multidisciplinary intestinal failure teams may have to adapt their clinical approaches to home care, outpatient care as well as hospital admission and discharge in order to keep this vulnerable group of patients as safe and well as possible during the unprecedented challenges that countries are facing during the pandemic. Equally, it is important that expert advice from intestinal failure teams is available when home parenteral nutrition (HPN)-dependent patients require admission with SARS-CoV-2 infection. The Home Artificial Nutrition & Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN) has developed a position paper to outline areas for intestinal failure teams to consider when managing patients with chronic intestinal failure during the SARS-CoV-2 pandemic.
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- 2020
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