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In the linear induction motor control system, the optical grating speed transducer is susceptible to strong magnetic field interference. What's more, it may reduce motor integration and raise device costs. Therefore a speed identification method to replace grating speed transducer is studied in this article. This speed identification method for linear induction motor mainly adopts Model Reference Adaptive Method (Abbreviated as MRAS) and Popov Hyperstability Theory. The research content of this paper can be divided into four parts. First, the mathematical model of the motor based on the model reference adaptive system structure is deduced. Second, the adaptive law of the estimated speed is solved by Popov hyper-stability theory, which ensures the stability of the system. Third, the simulation model of the linear induction motor speed identification control system based on model reference adaptation is built in the MATLAB environment. Finally, the simulation test and analysis are carried out. The simulation results show that the speed identification control system can track the actual speed of the linear induction motor well in the no-load operation and the load operation, and the stability of the system is guaranteed in the full speed range.

The microstructure and oxidation behaviour of the pure AlON ceramics and 8 wt.% SiC-AlON composite were investigated at 700-1500°C. With increasing oxidation temperature, the surface morphology of two ceramics showed a change from acicular to flaky-like and then to granular features. With the addition of nanosized SiC particles, the oxidation resistance of the ceramics was remarkably enhanced above 1100°C. This is attributed to the formation of a dense oxide layer composed of Al2O3, SiO2 and mullite, which could cover the whole matrix and suppress further penetration of oxygen. Due to the dense oxide layer, the oxidation kinetics of the 8 wt.% SiC-AlON composites conformed to a parabolic law, while that of the pure AlON conformed to a linear law. After oxidation at 1500 °C for 40 h, the weight gain of the 8 wt.% SiC-AlON composites was 3.07mg/cm2, which was only 22.5% of that of the pure AlON.

The synthesis and crystal structure of peptide 6,6′-dimethyl biphenyl hybrid are described. The title compound was synthesized by reaction between 6,6′-dimethyl-[1,1′-biphenyl]-2,2′-dicarbonyl dichloride in CH2Cl2, amine HN–proline–phenylalanine–alanine–COOMe and Et3N at 273 K under N2 atmosphere and characterized by single-crystal X-ray diffraction. The asymmetric unit contains one peptide molecule and a quarter of a water molecule. A disorder of a methyl and methoxycarbonyl group of one alanine residue is observed with occupancy ratio 0.502 (6):0.498 (6). The structure is consolidated by intra- and intermolecular hydrogen bonds.

A peptide biphenyl hybrid compound {systematic name: dimethyl 2,2′-[((2S,2′S)-2,2′-{[(2S,2′S)-1,1′-([1,1′-biphenyl]-2,2′-dicarbonyl)bis(pyrrolidine-1,2-diyl-2-carbonyl)]bis(azanediyl)}bis(3-phenylpropanoyl))bis(azanediyl)](2S,2′S)-dipropionate hemihydrate}, C50H56N6O10·0.5H2O, was prepared by coupling of [1,1′-biphenyl]-2,2′-dicarbonyl dichloride, triethylamine and the tripeptide Pro–Phe–Ala in CH2Cl2 at 273 K under an N2 atmosphere. In the crystal, the asymmetric unit contains the peptide biphenyl hybrid accompanied by one-half of a water molecule. A C atom of one of the proline rings is disordered between two positions in a 0.746 (11):0.254 (11) ratio. An important structural aspect of peptide compounds is their capacity to self-associate mediated by intermolecular and intramolecular hydrogen bonding. This characteristic can be useful in understanding the interactions between peptides and biomacromolecular targets, as well as to explain peptide properties.

Seeking a strategy for triggering the cryptic natural product biosynthesis to yield novel compounds in the plant-associated fungus Xylaria sp., the effect of culture conditions on metabolite production was investigated. A shift in the production of five known cytochalasin-type analogues 1–5 to six new α-pyrone derivatives, xylapyrones A–F (compounds 6–11), from a solid to a liquid medium was observed. These compounds were identified by analysis of 1D and 2D NMR and HRMS data. Compounds 1–3 showed moderate cytotoxicity against HepG2 and Caski cancer cell lines with IC50 values ranging from 25 to 63 μM and compounds 4–11 were found to be inactive, with IC50 values >100 μM.

Five new 2(5H)-furanone-type derivatives, pestalafuranones F–J (compounds 3–7), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The structures of these metabolites were elucidated by EIMS, HREIMS and NMR spectroscopic data. Compounds 1–7 exhibited no cytotoxic activities against the MDA-MB-231 and Caski cancer cell lines.

IoT devices and embedded systems are deployed in critical environments, emphasizing attributes like power efficiency and computational capabilities. However, these constraints stress the paramount importance of device security, stimulating the exploration of lightweight cryptographic mechanisms. This study introduces a lightweight architecture for authenticated encryption tailored to these requirements. The architecture combines the lightweight encryption of the LED block cipher with the authentication of the PHOTON hash function. Leveraging shared internal operations, the integration of these bases optimizes area–performance tradeoffs, resulting in reduced power consumption and a reduced logic footprint. The architecture is synthesized and simulated using Verilog HDL, Quartus II, and ModelSim, and implemented on Cyclone FPGA devices. The results demonstrate a substantial 14% reduction in the logic area and up to a 46.04% decrease in power consumption in contrast to the individual designs of LED and PHOTON. This work highlights the potential for using efficient cryptographic solutions in resource-constrained environments. [ABSTRACT FROM AUTHOR]

This paper introduces a novel approach to deal with the multi-objective optimization of a two-stage bevel helical gearbox by applying the Taguchi method and Grey Relation Analysis (GRA). The goal of the study is to find optimal main design factors that minimize the gearbox volume and maximize the gearbox efficiency. To accomplish this, five main design parameters were selected: the coefficients of wheel face width (CWFW) of the bevel and the helical gear sets, the allowable contact stresses (ACS) of the first and the second stages, and the gear ratio of the first stage. Furthermore, two single targets were investigated: minimum gearbox volumes, and maximum gearbox efficiency. Also, the multi-objective optimization problem is solved through two steps: Step 1 for closing the gap between variable levels and Step 2 for determining the optimal main design factors. The study's findings were used to introduce the optimum values of five major design parameters for designing a two-stage helical gearbox. [ABSTRACT FROM AUTHOR]

Objectives Vibrio parahaemolyticus is a major foodborne pathogen in aquatic animals and a threat to human health worldwide. This study investigated the prevalence, antimicrobial resistance, antimicrobial resistance genes (ARGs), and biofilm formation of V. parahaemolyticus strains isolated from fish mariculture environments in Cat Ba Island, Vietnam. Methods In total, 150 rearing water samples were collected from 10 fish mariculture farms in winter and summer. A polymerase chain reaction assay was used to identify V. parahaemolyticus, its virulence factors, and ARGs. The antimicrobial resistance patterns and biofilm formation ability of V. parahaemolyticus strains were investigated using the disk diffusion test and a microtiter plate-based crystal violet method, respectively. Results Thirty-seven V. parahaemolyticus isolates were recovered from 150 samples. The frequencies of the tdh and trh genes among V. parahaemolyticus isolates were 8.1% and 21.6%, respectively. More than 90% of isolates were susceptible to ceftazidime, cefotaxime, and chloramphenicol, but over 72% were resistant to ampicillin, tetracycline, and erythromycin. Furthermore, 67.57% of isolates exhibited multidrug resistance. The presence of ARGs related to gentamicin (aac(3)-IV), tetracycline (tetA) and ciprofloxacin (qnrA) in V. parahaemolyticus isolates was identified. Conversely, no ARGs related to ampicillin or erythromycin resistance were detected. Biofilm formation capacity was detected in significantly more multidrug-resistant isolates (64.9%) than non-multidrug-resistant isolates (18.9%). Conclusion Mariculture environments are a potential source of antibiotic-resistant V. parahaemolyticus and a hotspot for virulence genes and ARGs diffusing to aquatic environments. Thus, the prevention of antibiotic-resistant foodborne vibriosis in aquatic animals and humans requires continuous monitoring.

Multi-criteria decision making (MCDM) is a research area that entails analyzing various available options in a situation involving social sciences, medicine, engineering, and many other fields. This is due to the fact that it is used to select the best solution from a set of alternatives. The MCDM methods have been applied not only in economics, medicine, transportation, and the military, but also in mechanical processing processes to determine the best machining option. In this study, determining the best dressing mode for external grinding SKD11 tool steel using an MCDM method—the MABAC (multi-attributive border approximation area comparison) method—was introduced. The goal of this research is to find the best dressing mode for achieving the minimal surface roughness (RS), the maximum wheel life (T), and the minimal roundness (R) all at the same time. To perform this work, an experiment was carried out with six input parameters: the fine dressing depth, the fine dressing passes, the coarse dressing depth, the coarse dressing passes, the non-feeding dressing, and the dressing feed rate. In addition, the Taguchi method and an L16 orthogonal array were used to design the experiment. Furthermore, the MEREC (method based on the removal effects of criteria) and entropy methods were used to determine the weight of the criteria. The best dressing mode for external cylindrical grinding has been proposed based on the results. These findings were also confirmed by comparing them to the TOPSIS (technique for order of preference by similarity to ideal solution) and MARCOS (measurement of alternatives and ranking according to compromise solution) methods. [ABSTRACT FROM AUTHOR]

Summary: Background: No study has compared the virological and immunological status of young people with perinatally-acquired HIV infection (P-HIV) with that of people with HIV adulthood (A-HIV) having a similar duration of infection. Methods: 5 French cohorts of P-HIV and A-HIV patients with a known date of HIV-infection and receiving antiretroviral treatment (ART), were used to compare the following proportions of: virological failure (VF) defined as plasma HIV RNA ≥ 50 copies/mL, CD4 cell percentages and CD4:CD8 ratios, at the time of the most recent visit since 2012. The analysis was stratified on time since infection, and multivariate models were adjusted for demographics and treatment history. Findings: 310 P-HIV were compared to 1515 A-HIV (median current ages 20.9 [IQR:14.4–25.5] and 45.9 [IQR:37.9–53.5] respectively). VF at the time of the most recent evaluation was significantly higher among P-HIV (22.6%, 69/306) than A-HIV (3.3%, 50/1514); p ≤ 0.0001. The risk of VF was particularly high among the youngest children (2–5 years), adolescents (13–17 years) and young adults (18–24 years), compared to A-HIV with a similar duration of infection: adjusted Odds-Ratio (aOR) 7.0 [95% CI: 1.7; 30.0], 11.4 [4.2; 31.2] and 3.3 [1.0; 10.8] respectively. The level of CD4 cell percentages did not differ between P-HIV and A-HIV. P-HIV aged 6–12 and 13–17 were more likely than A-HIV to have a CD4:CD8 ratio ≥ 1: 84.1% vs. 58.8% (aOR = 3.5 [1.5; 8.3]), and 60.9% vs. 54.7% (aOR = 1.9 [0.9; 4.2]) respectively. Interpretation: P-HIV were at a higher risk of VF than A-HIV with a similar duration of infection, even after adjusting for treatment history, whereas they were not at a higher risk of immunological impairment. Exposure to viral replication among young patients living with HIV since birth or a very early age, probably because of lower adherence, could have an impact on health, raising major concerns about the selection of resistance mutations and the risk of HIV transmission. Funding: Inserm - ANRS MIE.

For most Internet-of-Things (IoT) applications, embedded processors typically execute lightweight tasks such as sensing and communication. The typical IoT program senses some information and sends them via a channel, usually a wireless channel with an RF circuit. These IoT nodes often require a system with networking capabilities and a low-power harvester implementation. This brief presents a sub-μW 8-bit processor which is suitable for such IoT applications. The processor implements the Open8 Instruction Set Architecture (ISA) with an 8-bit datapath and 16-bit bus addressing. The chip contains the processor and a 4-KB of Static Random-Access-Memory (SRAM), and is fabricated by the 65-nm Silicon-On-Thin-Box (SOTB) process. The SOTB process is one of the Fully-Depleted Silicon-On-Insulator (FD-SOI) technology. Hence, the ability to control biasing voltages is one of its key advantages to achieve low-power. The experimental results show that the power consumption at the reverse-body bias can reach down to 50-nW with 0.5-V supply voltage and 32-KHz operating clock frequency. The completed microcontroller consists of the Open8 processor, 32-KB of Read-Only-Memory (ROM), 4-KB of SRAM, Serial Peripheral Interface (SPI), SPI programmer, debug module, General-Purpose In-Outs (GPIOs), and UART. The system was tested using an XC7A100T Xilinx Field-Programmable Gate Array (FPGA); it yielded 1.8% of the total FPGA utilization. [ABSTRACT FROM AUTHOR]

Coptosapelta flavescens Korth. is one of the medicinal plants used as a traditional medicine in Vietnam for a long time. However, few documents proved its safety for a long time. Therefore, the study aimed to determine the toxicity effects of the aqueous extract of C. flavescens by determining its effects after subchronic oral administration in Swiss albino mice. The toxicity of C. flavescens extract was tested at doses of 400 and 1200 mg/kg, respectively, over 30 and 60 days on an in vivo model. Animal weight, behavior, and condition changes were monitored throughout the process. At the end of the observation periods, hematological indices and histopathological features of the animal specimens were analyzed. The administration of C. flavescens extract at doses of 400 and 1200 mg/kg caused a weight difference in male mice after 30 days and in both sexes after 60 days of administration compared to the control group. There were no significant changes in hematological parameters and biochemical indexes of the liver and kidney compared with the control group. The histological structure of the liver showed changes when treated with C. flavescens at both doses after 60 days, whereas the histological structure of the kidneys exhibited differences only at the dose of 400 mg/kg. Overall, the findings of this study indicate that Coptosapelta flavescens Korth. is unlikely to have subacute and subchronic oral toxicity. However, there are some minor effects on the liver and kidneys.

With the large-scale grid connection of new energy power, the random fluctuation existing in the power system is intensified, which leads to frequent fluctuation of load instructions of thermal power units. It is of great significance to improve the variable load performance of the coal-fired units. It is more difficult to control the superheated steam temperature (SST). In order to improve the control performance of SST, a state variable fuzzy predictive control method is proposed in this paper. Firstly, Takagi-Sugeno fuzzy state observer is used to approximate the non-linear plant of the SST. At the same time, based on the state observer, a fuzzy state feedback controller is designed to improve its dynamic characteristics. Thirdly, based on the extended predictive model of the state feedback controller, a model predictive controller is designed to realize the SST tracking control. Dynamic simulation shows the effectiveness of the strategy. [ABSTRACT FROM AUTHOR]

The authors present a novel wideband two‐dimensional voltage‐controlled attenuator (VCA). The proposed design employs both stacked‐FET configuration and distributed structure to achieve wideband performance, high power, and high dynamic range simultaneously. A systematic design methodology is also illustrated along with a fabricated prototype to verify the concept. The chip fabricated in a 0.15‐μm Gallium Arsenide (GaAs) process exhibiting a measured power at 1‐dB compression (P1dB) of 25.5 dBm with a corresponding dynamic range of 32 dB. The insertion loss ranges from 2 to 5 dB over the bandwidth from 2 to 40 GHz. Furthermore, the chip is not only very compact (0.84 mm2), but it also requires only a single positive supply voltage, which makes it more appealing to highly integrated wireless applications. [ABSTRACT FROM AUTHOR]

Abstract When optimizing the process parameters of the acidic ethanolic organosolv process, the aim is usually to maximize the delignification and/or lignin purity. However, process parameters such as temperature, time, ethanol and catalyst concentration, respectively, can also be used to vary the structural properties of the obtained organosolv lignin, including the molecular weight and the ratio of aliphatic versus phenolic hydroxyl groups, among others. This review particularly focuses on these influencing factors and establishes a trend analysis between the variation of the process parameters and the effect on lignin structure. Especially when larger data sets are available, as for process temperature and time, correlations between the distribution of depolymerization and condensation reactions are found, which allow direct conclusions on the proportion of lignin's structural features, independent of the diversity of the biomass used. The newfound insights gained from this review can be used to tailor organosolv lignins isolated for a specific application.

This paper uses first-order shear deformation theory and the finite element method to analyze the vibrations of rectangular plates with one or more cracks. The study investigated the influence of cracks (length, angle of inclination), the number of cracks, and the ratio of plate thickness to the natural vibration frequency of the plate, using phase field simulation. Plate thickness varies nonlinearly with the parabolic function. The results of the proposed method were compared with reputable studies to verify its reliability. In addition, some pictures of the characteristic vibration patterns of the plate with varying thickness are presented when cracks appear.

Attention should be paid to tunnels' seismic behaviour since many of them have been damaged by earthquakes. The paper presented a seismic study of a shallow circular tunnel by physical modelling on shaking table test. A small scale tunnel model of the Hanoi pilot metro line's underground segment was placed in the middle of a rigid soil container and buried in Red River sand (Vietnam). The table was vibrated along the soil container's long wall, with a simulated seismic wave created from the 1788 Tolmezzo (Italia) accelerogram. Five testing campaigns were executed, and the model's acceleration data were studied. The uni-directional vibration created by the shaking table caused the three-directional vibration of the physical model. The Fast Fourier Transform (FFT) frequency spectrum analyses were performed. The vibration characteristics of the model (i.e., frequency graph's structure, maximal acceleration, dominant frequency, strong-motion duration) in three orthogonal directions under the artificial earthquake action were compared. The obtained results proved the complicated seismic impacts on a shallow tunnel.

The synthesis and crystal structure of peptide 6,60-dimethyl biphenyl hybrid are described. The title compound was synthesized by reaction between 6,60- dimethyl-[1,1'-biphenyl]-2,2'-dicarbonyl dichloride in CH2Cl2, amine HN-- proline--phenylalanine--alanine--COOMe and Et3N at 273 K under N2 atmosphere and characterized by single-crystal X-ray diffraction. The asymmetric unit contains one peptide molecule and a quarter of a water molecule. A disorder of a methyl and methoxycarbonyl group of one alanine residue is observed with occupancy ratio 0.502 (6):0.498 (6). The structure is consolidated by intra- and intermolecular hydrogen bonds. [ABSTRACT FROM AUTHOR]

A peptide biphenyl hybrid compound {systematic name: dimethyl 2,2'-[((2S,2'S)-2,2'-{[(2S,2'S)-1,1'-([1,1'-biphen­yl]-2,2'-dicarbon­yl)bis­(pyrrolidine-1,2-diyl-2-carbon­yl)]bis­(aza­nedi­yl)}bis­(3-phenyl­propano­yl))bis­(aza­nedi­yl)](2S,2'S)-dipropionate hemihydrate}, C50H56N6O10·0.5H2O, was prepared by coupling of [1,1'-biphen­yl]-2,2'-dicarbonyl dichloride, tri­ethyl­amine and the tripeptide Pro-Phe-Ala in CH2Cl2 at 273K under an N2 atmosphere. In the crystal, the asymmetric unit contains the peptide biphenyl hybrid accompanied by one-half of a water mol­ecule. A C atom of one of the proline rings is disordered between two positions in a 0.746(11):0.254(11) ratio. An important structural aspect of peptide compounds is their capacity to self-associate mediated by inter­molecular and intra­molecular hydrogen bonding. This characteristic can be useful in understanding the inter­actions between peptides and biomacromolecular targets, as well as to explain peptide properties. [ABSTRACT FROM AUTHOR]

Overhead hoist transportation systems (OHTS) have been the subject of worldwide research and development in recent years. The majority of these systems are utilized in semi-automated or fully automated factories. This article proposes a new solution for OTHS based on the concept of the modulation of mobile units that can move on a railway structure from one point to another. The OHTS mentioned in this article is a group of shuttles that can operate independently but which also have the ability to cooperate together to complete the desired tasks. By using the space below the ceiling, this system can operate without affecting the original design of the factories. There are many potential fields of application for picking-up and delivering, such as the medical field, the food and beverage fields, automotive and electrical appliances, etc. Moreover, by applying Dijkstra’s algorithm in the controller design, the transportation speed among the stations in the whole system can be improved. The real prototype of the whole system, including three shuttles, is also manufactured to explore and assess the design and operation of the proposed system and its controller.

Recently, the development of Kubernetes (K8s) containerization platform has enabled cloud-based, lightweight, highly scalable, and agile services in both general and telco use-cases. Ensuring high availability, reliable and continuous containerized services is a major requirement of service providers to provide fault-tolerance, transparent service experiences to end-users. To satisfy this requirement, fault prediction and proactive stateful service recovery features must be applied in cloud systems. Prior proactive failure recovery approaches mostly focused on either improving fault prediction performance based on different machine learning time series forecasting techniques or optimizing recovery service placement after fault prediction. However, a mechanism that enables stateful containerized service migration from the predicted faulty node to the healthy destination node has not been studied. Service migration in previous proactive works is only simulated or performed by virtual machine (VM) migration techniques. In this paper, we propose a proactive stateful fault-tolerant system for K8s containerized services that pipelines a Bidirectional Long Short-Term Memory (Bi-LSTM) fault prediction framework and a novel K8s stateful service migration mechanism for service recovery. Experimental results show how the Bi-LSTM model improved prediction performance against other time-series forecasting models used prior proactive works. We then combined the Bi-LSTM fault prediction framework with both the default K8s and our stateful migration mechanisms. The comparison between these two proactive systems proves our system efficiency in terms of reducing Quality of Service (QoS) violation percentage and service recovery time.

This study developed an ankle rehabilitation device for post-stroke patients. First, the research models and dynamic equations of the device are addressed. Second, the Sliding Mode Controller for the ankle rehabilitation device is designed, and the device's response is simulated on the software MATLAB. Third, the ankle rehabilitation device is successfully manufactured from aluminum and uses linear actuators to emulate dorsiflexion and plantarflexion exercises for humans. The advantages of the device are a simple design, low cost, and mounts onto rehabilitative equipment. The device can operate fast through experiments, has a foot drive mechanism overshoot of 0°, and a maximum angle error of 1°. Moreover, the rehabilitation robot can operate consistently and is comfortable for stroke patients to use. Finally, we will fully develop the device and proceed to clinical implementation.

Peptic ulcer disease (PUD) is a common disease and frequently encountered in the clinic. Accumulating evidence suggests that PUD is associated with the gastrointestinal microbiota. Electroacupuncture (EA) is an improved version of acupuncture, which can improve the clinical effect by increasing the stimulation and delivering appropriate electrical pulses to needles. This method has been widely used in the treatment of peptic ulcer disease. However, its effect on gastrointestinal microbiota remains unclear. Therefore, in the present study, the ameliorative effect of EA was evaluated on the gastroduodenal mucosa, and the regulatory effect of the gastroduodenal microbiota was assessed in PUD mice. A total of 48 male Kun Ming mice were randomly divided into the following groups: normal control group (NC), PUD model group (PUD), Shousanli group (LI10), and Zusanli group (ST36) (n=12). The mice in groups LI10 and ST36 were treated with EA at LI10 and ST36, respectively. This intervention was continued for 7 days. Subsequently, we evaluated the morphological changes in the gastric and duodenal mucosa, and specific indices were measured, including the contents of serum dopamine (DA), the trefoil factor (TFF), and the vasoactive intestinal peptide (VIP). In addition, the gastric and duodenal microbiota were assessed via 16S ribosomal DNA sequencing. The results indicated that EA at LI10 or ST36 significantly reduced the injury of the gastroduodenal mucosa in PUD mice. The gastric microbial community structure of the groups LI10 and ST36 was similar to that of the NC group following comparison with the microbial community structure of the PUD model group. Moreover, the abundance of Firmicutes in the stomach was decreased, whereas that of Bacteroidetes was increased, and the abundance of Firmicutes in the duodenum was decreased. Furthermore, the microbial diversity and richness of the gastric microbiota in group LI10 were also significantly increased, and the serum dopamine and trefoil factor levels in group ST36 were significantly increased. Therefore, it is suggested that EA ameliorating PUD is in association with improving the levels of DA and TFF and regulating the relative abundances of Firmicutes and Bacteroidetes in the gastric microbiota.

For a long time, ethnic minorities in Ninh Thuan province have combined ''Day Khai'' (Coptosapelta flavescens Korth) with many other medicinal herbs, creating an esoteric remedy called ''Cao Khai''-an aqueous extract from Day Khai. This study tested an aqueous extract from ''Day Khai'' for total phenolics, total flavonoids, antioxidant, and anti-inflammatory activity in an in vivo mice model. The aqueous extracts of raw materials C. flavescens collected in different regions were found to have phenolics, flavonoids, and antioxidant capacity in vitro according to DPPH, ABTS, RP, TAC, and FRAP methods. This study evaluated the effect of C. flavescens on arthritis of Complete Freund's adjuvant (CFA) induced-mice by observing changes in the degree of edema in the leg joints blood index and histology. The findings indicated that the ''Cao Khai'' had anti-inflammatory benefits and lowered the inflammatory symptoms in mice equivalent to Mobic medications (p < 0.05) while also limiting cartilage tissue damage after 14 days of usage. As a result, it is clear that ''Cao Khai'' can be considered a medicinal herb with tremendous potential for usage as an addition to illness therapy that should be protected and cultivated.

Ebstein anomaly (EA) results from the failure of proper delamination of the tricuspid valve leaflets from the right ventricle (RV) myocardium. The severity of EA occurs on a spectrum that results in varying degrees of tricuspid regurgitation, atrial dilation, RV dilation, and dysfunction. These effects have the potential to create substrates that can give rise to atrial arrhythmia, ventricular arrhythmia, and a greater incidence of Wolff–Parkinson–White (WPW) syndrome Wackel et al. (2018) accounting for 0.5% of all congenital heart diseases (Oh et al. 1985). In the case of atrial fibrillation and WPW, it is very dangerous for the patient because of hemodynamic compromise, syncope, and sudden death. In this case report, we share our experience in using radiofrequency ablation to ablate right lateral accessory pathway, with modified Carpentier technique in operation to treat an adult patient diagnosed with Ebstein anomaly, atrial septal defect, atrial fibrillation, and WPW syndrome.

The center of gravity of a vehicle (CG) is a critical parameter in influencing the quality of driveability and safety, such as for preventing rollover accidents. Therefore, it is important to identify a vehicle’s CG in practical situations. In particular, it is strongly desired to make it possible to measure the height of the CG of trucks and trailers freighted with various voluminous and heavy loads on business operation. The technology of Weigh-In-Motion (WIM) is being developed to identify the gross weight of trucks and trailers and detect overload. In this paper, the authors propose a method for the estimation of a vehicle’s CG, especially the height of CG, based on the WIM system. The basic theory is described at first, and the validity is shown by means of basic experiments using a light truck and a motorbike.

This study presents a numerical investigation of the elastic critical lateral-torsional buckling of a steel beam subjected to simultaneous transverse loading at the top flange and negative end moments. Here, the elastic critical buckling of the steel beam was estimated by utilizing the finite element software ABAQUS. In addition, the influence of the length-to-height ratio was taken into account. Additionally, the predicted values for elastic critical buckling when applying existing design codes and a previous study were also analyzed and compared to the numerical results of the finite element analysis. The result of the comparison revealed that the projected values from the design codes and the study are conservative for the majority of cases and have a tendency to be too conservative when the length-to-height ratio increases. Furthermore, a new equation with a factor considering the influence of the length-to-height ratio and transverse loading on the top flange is proposed, and the proposed equation shows sufficient accuracy and less conservative values for most cases.

Thermotolerant yeasts are widely considered to be alternative strains to traditional yeasts for bioethanol production at high temperatures. In this study, thirty-two yeasts isolated from lychees were screened for thermotolerance, and seven selected isolates were identified as Candida tropicalis (isolates H8, H19, and H23), Meyerozyma guilliermondii (isolates H1 and H12) and Saccharomyces cerevisiae (isolates H10 and H18). They tolerated up to 45 °C, 12% (v/v) ethanol concentration, 10 g/L acetic acid, and 5 g/L furfural, respectively, and produced 47.96 to 70.18 g/L of ethanol from 160 g/L glucose at 40 °C during 48 h of fermentation. Among the evaluated yeasts, M. guilliermondii H1 showed great potential for second-generation bioethanol fermentation with its ability to ferment xylose and arabinose. Under the optimal conditions resulting from a Plackett Burman design and a Box Behnken design, the highest ethanol concentration of 11.12 g/L was produced from 40 g/L substrate-based sugarcane bagasse hydrolysate (non-detoxified hydrolysate) at 40 °C by M. guilliermondii H1. These findings suggested that the newly isolated thermotolerant yeast M. guilliermondii H1 is a good candidate for ethanol production from agricultural wastes.