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2 results on '"Koutarou Hattori"'

1. A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor.

Author

Hiroaki Shibahara, Michiyo Higashi, Seiya Yokoyama, Karine Rousseau, Iwao Kitazono, Masahiko Osako, Hiroshi Shirahama, Yukie Tashiro, Yasuhiro Kurumiya, Michihiko Narita, Shingo Kuze, Hiroshi Hasagawa, Takehito Kato, Hitoshi Kubota, Hideaki Suzuki, Toshiyuki Arai, Yu Sakai, Norihiro Yuasa, Masahiko Fujino, Shinji Kondo, Yoshichika Okamoto, Tatsuyoshi Yamamoto, Takashi Hiromatsu, Eiji Sasaki, Kazuhisa Shirai, Satoru Kawai, Koutarou Hattori, Hideki Tsuji, Osamu Okochi, Masaki Sakamoto, Akinobu Kondo, Naomi Konishi, Surinder K Batra, and Suguru Yonezawa

Subjects
Medicine, Science
Abstract

Mucins are implicated in survival in various cancers, but there have been no report addressed on survival in appendiceal carcinoma, an uncommon disease with different clinical and pathological features from those of other colon cancers. We aimed to investigate the clinical implications of expression of mucins in appendiceal carcinoma.Expression profiles of MUC1, MUC2, MUC3, MUC4, MUC5AC, MUC6, MUC16 and MUC17 in cancer tissue were examined by immunohistochemistry in 108 cases of surgically resected appendiceal carcinoma.The following relationships of mucins with clinicopathologic factors were identified: MUC1 with positive lymphatic invasion (p = 0.036); MUC2 with histological type (mucinous carcinoma, p

Published
2014
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2. A Comprehensive Expression Analysis of Mucins in Appendiceal Carcinoma in a Multicenter Study: MUC3 Is a Novel Prognostic Factor

Author

Hideki Tsuji, Satoru Kawai, Toshiyuki Arai, Koutarou Hattori, Yukie Tashiro, Takashi Hiromatsu, Michihiko Narita, Shingo Kuze, Yasuhiro Kurumiya, Iwao Kitazono, Karine Rousseau, Hitoshi Kubota, Masahiko Osako, Eiji Sasaki, Norihiro Yuasa, Osamu Okochi, Masaki Sakamoto, Masahiko Fujino, Naomi Konishi, Hiroshi Hasagawa, Hiroaki Shibahara, Hiroshi Shirahama, Akinobu Kondo, Shinji Kondo, Michiyo Higashi, Yoshichika Okamoto, Suguru Yonezawa, Tatsuyoshi Yamamoto, Hideaki Suzuki, Surinder K. Batra, Seiya Yokoyama, Yu Sakai, Kazuhisa Shirai, and Takehito Kato

Subjects
Adult, Male, Pathology, medicine.medical_specialty, Clinical Pathology, Colorectal cancer, Lymphovascular invasion, lcsh:Medicine, Pathology and Laboratory Medicine, Metastasis, Young Adult, Diagnostic Medicine, Pancreatic cancer, Gastrointestinal Tumors, Carcinoma, medicine, Medicine and Health Sciences, Mucinous carcinoma, Humans, lcsh:Science, Survival analysis, Aged, Aged, 80 and over, Multidisciplinary, business.industry, Cancer Risk Factors, Gene Expression Profiling, lcsh:R, Mucins, Cancer, Cancers and Neoplasms, Middle Aged, medicine.disease, Prognosis, Survival Analysis, 3. Good health, Oncology, Appendiceal Neoplasms, Multivariate Analysis, lcsh:Q, Female, business, Research Article
Abstract

Background Mucins are implicated in survival in various cancers, but there have been no report addressed on survival in appendiceal carcinoma, an uncommon disease with different clinical and pathological features from those of other colon cancers. We aimed to investigate the clinical implications of expression of mucins in appendiceal carcinoma. Methods Expression profiles of MUC1, MUC2, MUC3, MUC4, MUC5AC, MUC6, MUC16 and MUC17 in cancer tissue were examined by immunohistochemistry in 108 cases of surgically resected appendiceal carcinoma. Results The following relationships of mucins with clinicopathologic factors were identified: MUC1 with positive lymphatic invasion (p = 0.036); MUC2 with histological type (mucinous carcinoma, p

Published
2014

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