7 results on '"Milone, Annarita"'
Search Results
2. A novel multidimensional questionnaire for the assessment of emotional dysregulation in adolescents: Reactivity, Intensity, Polarity and Stability questionnaire–youth version (RIPoSt–Y)
- Author
-
Elena Valente, Flavia Drago, Stefano Berloffa, Francesca Placini, Anna Rita Montesanto, Gianluca Sesso, Nina Loriaux, Agnese Molesti, Gabriele Masi, Simone Pisano, Annarita Milone, Valentina Viglione, Silvia Boldrini, Sesso, Gianluca, Milone, Annarita, Drago, Flavia, Viglione, Valentina, Berloffa, Stefano, Boldrini, Silvia, Loriaux, Nina, Valente, Elena, Molesti, Agnese, Placini, Francesca, Montesanto, Anna Rita, Pisano, Simone, and Masi, Gabriele
- Subjects
Psychometrics ,Adolescent ,Bipolar disorder ,Emotions ,Concurrent validity ,Reproducibility of Result ,Emotional dysregulation ,CBCL ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,medicine ,Humans ,ADHD ,Surveys and Questionnaire ,Reactivity (psychology) ,Emotion ,Schools ,Questionnaire ,Reproducibility of Results ,Construct validity ,medicine.disease ,030227 psychiatry ,Psychiatry and Mental health ,Clinical Psychology ,Convergent validity ,Self Report ,Psychology ,Construct (philosophy) ,Psychometric ,030217 neurology & neurosurgery ,Human ,Clinical psychology - Abstract
Background The failure to regulate emotions, namely emotional dysregulation (ED), is a relevant construct in adolescent psychiatry, in terms of prognostic and developmental implications. We developed and validated a novel self-report questionnaire for the assessment of ED, the RIPoSt-Y, both in clinical and non-clinical samples. Methods Items selection and subscales construction were conducted on healthy controls (n=374), while test-retest reliability was evaluated in a subsample (n=72); internal consistency was examined both in the control group and in two clinical samples, respectively including patients with Bipolar Spectrum Disorders (BSD; n=44) and ADHD (n=34). Construct, concurrent and convergent validity were also assessed. Results Thirty-one items were finally retained, and three subscales were identified (Affective Instability, Emotional Reactivity, Interpersonal Sensitivity). Test-retest was significant for each subscale with moderate-to-good correlations, and internal consistency showed good-to-excellent coefficients. Construct validity was supported by significant differences between patients and controls and gender-related differences. Concurrent validity was confirmed through significant associations with two subscales of the CHT-Q, while convergent validity proved to be significant with the CBCL/YSR dysregulation-profile. Cut-offs were also computed to discriminate clinically significant scores of ED. Limitations The use of a school-based survey to recruit controls could have biased our results; gender distributions between clinical and non-clinical samples were significantly different. Conclusions Our novel questionnaire proved to be a valid and reliable tool able to assess the presence of ED in youths and to characterize this fundamental construct in its multidimensional facets.
- Published
- 2021
3. Lithium treatment in bipolar adolescents: a follow-up naturalistic study
- Author
-
Stefano Berloffa, Simone Pisano, Annarita Milone, Valentina Viglione, Gabriele Masi, Gabriella Bruni, Maria Mucci, Giulia Scrinzi, Masi, Gabriele, Milone, Annarita, Scrinzi, Giulia, Mucci, Maria, Viglione, Valentina, Bruni, Gabriella, Berloffa, Stefano, and Pisano, Simone
- Subjects
safety ,medicine.medical_specialty ,Neuropsychiatric Disease and Treatment ,Lithium (medication) ,Sedation ,QT interval ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,White blood cell ,Internal medicine ,medicine ,0501 psychology and cognitive sciences ,adolescents ,Bipolar disorder ,Original Research ,bipolar disorder ,business.industry ,05 social sciences ,Thyroid ,medicine.disease ,3. Good health ,030227 psychiatry ,medicine.anatomical_structure ,lithium ,adolescent ,Long term data ,medicine.symptom ,business ,050104 developmental & child psychology ,Hormone ,medicine.drug - Abstract
Gabriele Masi,1 Annarita Milone,1 Giulia Scrinzi,2 Maria Mucci,1 Valentina Viglione,1 Gabriella Bruni,1 Stefano Berloffa,1 Simone Pisano3 1IRCCS Stella Maris Foundation, Developmental Psychiatry and Psychopharmacology Unit, Pisa, Italy; 2Child Neuropsychiatry Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy; 3Clinic of Child and Adolescent Neuropsychiatry, Department of Medicine and Surgery, University of Salerno, Salerno, Italy Background: Although lithium is currently approved for the treatment of bipolar disorders in youth, long term data, are still scant. The aim of this study was to describe the safety and efficacy of lithium in referred bipolar adolescents, who were followed up at the 4th (T1) and 8th (T2) month of treatment.Methods: The design was naturalistic and retrospective, based on a clinical database, including 30 patients (18 males, mean age 14.2±2.1 years).Results: Mean blood level of lithium was 0.69±0.20 mEq/L at T1 and 0.70±0.18 mEq/L at T2. Both Clinical Global Impression-Severity (CGI-S) and Children Global Assessment Scale (C-GAS) scores improved from baseline (CGI-S 5.7±0.5, C-GAS 35.1±3.7) to T1 (CGI-S 4.2±0.70, C-GAS 46.4±6.5; P
- Published
- 2018
4. The Role of Executive Functions in the Development of Empathy and Its Association with Externalizing Behaviors in Children with Neurodevelopmental Disorders and Other Psychiatric Comorbidities
- Author
-
Antonio Narzisi, Pietro Muratori, Chiara Pfanner, Laura Ruglioni, Emanuela Inguaggiato, Gianluca Sesso, Gabriele Masi, Annarita Milone, Simone Pisano, Paola Cristofani, Pamela Fantozzi, Elena Valente, Lisa Polidori, Chiara Cristofani, Cristofani, Chiara, Sesso, Gianluca, Cristofani, Paola, Fantozzi, Pamela, Inguaggiato, Emanuela, Muratori, Pietro, Narzisi, Antonio, Pfanner, Chiara, Pisano, Simone, Polidori, Lisa, Ruglioni, Laura, Valente, Elena, Masi, Gabriele, and Milone, Annarita
- Subjects
medicine.medical_treatment ,media_common.quotation_subject ,autism spectrum disorder ,Empathy ,Article ,lcsh:RC321-571 ,03 medical and health sciences ,0302 clinical medicine ,Social cognition ,medicine ,0501 psychology and cognitive sciences ,empathy ,attention deficit and hyperactivity disorder ,lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry ,media_common ,General Neuroscience ,05 social sciences ,executive functions ,medicine.disease ,Executive functions ,Cognitive behavioral therapy ,Behavior Rating Inventory of Executive Function ,Prosocial behavior ,disruptive behavior disorders ,Autism spectrum disorder ,Autism ,Psychology ,disruptive behavior disorder ,030217 neurology & neurosurgery ,050104 developmental & child psychology ,Clinical psychology - Abstract
Executive functions have been previously shown to correlate with empathic attitudes and prosocial behaviors. People with higher levels of executive functions, as a whole, may better regulate their emotions and reduce perceived distress during the empathetic processes. Our goal was to explore the relationship between empathy and executive functioning in a sample of children and adolescents diagnosed with Attention Deficit and Hyperactivity Disorder alone or associated with comorbid Disruptive Behavior Disorders and/or Autism Spectrum Disorder. We also aimed to examine the role of empathic dimensions and executive skills in regulating externalizing behaviors. The 151 participants with ADHD were assigned to four groups according to their psychiatric comorbidity (either &ldquo, pure&rdquo, or with ASD and/or ODD/CD) and assessed by means of either parent- or self-reported questionnaires, namely the BRIEF&minus, 2, the BES, and the IRI. No questionnaire was found to discriminate between the four groups. Affective Empathy was found to positively correlate with Emotional and Behavioral Regulation competences. Furthermore, Aggressiveness and Oppositional Defiant Problems were positively associated with Executive Emotional and Behavioral Regulation competences. On the other hand, Rule-Breaking Behaviors and Conduct Problems were negatively associated with Affective Empathy and with Behavioral skills. Our study provides an additional contribution for a better understanding of the complex relationship between empathic competence and executive functions, showing that executive functioning and empathic attitudes interact with each other to regulate aggressive behaviors. This study further corroborates developmental models of empathy and their clinical implications, for which externalizing behaviors could be attenuated by enhancing executive functioning skills.
- Published
- 2020
5. Six-year outcome for children with ODD or CD treated with the coping power program
- Author
-
Pietro Muratori, Annarita Milone, Valentina Levantini, Laura Ruglioni, Gabriele Masi, Simone Pisano, Furio Lambruschi, John E. Lochman, Muratori, Pietro, Milone, Annarita, Levantini, Valentina, Ruglioni, Laura, Lambruschi, Furio, Pisano, Simone, Masi, Gabriele, and Lochman, John E
- Subjects
Conduct Disorder ,Male ,Coping (psychology) ,Child Behavior Disorder ,Adolescent ,Coping power program ,Child Behavior Disorders ,Oppositional defiant disorder ,Follow-Up Studie ,03 medical and health sciences ,0302 clinical medicine ,Callous Unemotional ,Adaptation, Psychological ,Outcome Assessment, Health Care ,medicine ,Humans ,Child ,Biological Psychiatry ,Callous unemotional ,business.industry ,medicine.disease ,Mental health ,Aggressive Behavior ,030227 psychiatry ,Psychiatry and Mental health ,Conduct disorder ,Attention Deficit and Disruptive Behavior Disorders ,Oppositional defiant ,Attention Deficit and Disruptive Behavior Disorder ,Psychotherapy, Group ,Female ,Substance use ,business ,Check List ,030217 neurology & neurosurgery ,Clinical psychology ,Human ,Follow-Up Studies - Abstract
Children with severe aggressive behavioral problems are one of the groups most frequently referred to mental health clinics, and they engage in behaviors that put them at risk for substance use problems and a host of other negative outcomes. The present study aimed to assess the long-term outcome (six-year follow up) of the Coping Power Program delivered in a mental health hospital for children with behavioral disorders. We recruited one hundred and twenty children (mean age = 9.9, SD = 0.85), twenty-three patients were lost during the follow-ups. The sample of the current study included sixty-seven youths with Oppositional Defiant Disorder, and thirty with Conduct Disorder. We used Child Behavior Check List, Inventory of Callous Unemotional traits and a youth survey to evaluate substance use. After the baseline evaluation they were allocated to Coping Power or to a generic multi-component treatment. Coping Power produced significant reduction in Callous Unemotional traits, relative to the control condition; Coping Power seems to be effective also in reducing the rate of substance use. However, no differences have been found in externalizing behavior reduction in the two groups. This study contributes to the successful dissemination of best-practice treatments in public mental health services for children.
- Published
- 2018
6. Putative Mechanisms of Action and Clinical Use of Lithium in Children and Adolescents: A Critical Review
- Author
-
Gennaro Catone, Giulia Scrinzi, Giangennaro Coppola, Gabriele Masi, Paramala Santosh, Emilio Clementi, Simone Pisano, Annarita Milone, Marco Pozzi, Carmela Bravaccio, Pisano, Simone, Pozzi, Marco, Catone, Gennaro, Scrinzi, Giulia, Clementi, Emilio, Coppola, Giangennaro, Milone, Annarita, Bravaccio, Carmela, Santosh, Paramala, and Masi, Gabriele
- Subjects
adolescents ,children ,efficacy ,lithium ,mechanism of action ,pharmacokinetics ,safety ,Pediatrics ,Bipolar Disorder ,Lithium (medication) ,Poison control ,Efficacy ,0302 clinical medicine ,Antimanic Agents ,Medicine ,Pharmacology (medical) ,pharmacokinetic ,Child ,Children ,Randomized Controlled Trials as Topic ,Clinical Trials as Topic ,Age Factors ,General Medicine ,Adolescents ,Lithium ,Mechanism of action ,Pharmacokinetics ,Safety ,Adolescent ,Antidepressive Agents ,Depressive Disorder, Major ,Humans ,Lithium Compounds ,Psychiatry and Mental health ,Neurology ,Conduct disorder ,Schizophrenia ,medicine.drug ,medicine.medical_specialty ,Young Mania Rating Scale ,Article ,03 medical and health sciences ,Bipolar disorder ,Pharmacology ,Depressive Disorder ,business.industry ,Major ,medicine.disease ,030227 psychiatry ,Clinical trial ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Background:Lithium is a first-line treatment for bipolar disorder in adults, but its mechanism of action is still far from clear. Furthermore, evidences of its use in pediatric populations are sparse, not only for bipolar disorders, but also for other possible indications.Objectives:To provide a synthesis of published data on the possible mechanisms of action of lithium, as well as on its use in pediatric samples, including pharmacokinetics, efficacy, and safety data.Methods:Clinical trials in pediatric samples with at least one standardized measure of efficacy/ effectiveness were included in this review. We considered: i) randomized and open label trials, ii) combination studies iii) augmentation studies iv) case series including at least 5 patients.Results:Different and non-alternative mechanisms of action can explain the clinical efficacy of lithium. Clinical studies in pediatric samples suggest that lithium is effective in managing manic symptoms/episodes of bipolar disorder, both in the acute phase and as maintenance strategy. Efficacy on depressive symptoms/phases of bipolar disorder is much less clear, while studies do not support its use in unipolar depression and severe mood dysregulation. Conversely, it may be effective on aggression in the context of conduct disorder. Other possible indications, with limited published evidence, are the acute attacks in Kleine-Levin syndrome, behavioral symptoms of X-fragile syndrome, and the management of clozapine- or chemotherapy- induced neutropenia. Generally, lithium resulted relatively safe.Conclusions:Lithium seems an effective and well-tolerated medication in pediatric bipolar disorder and aggression, while further evidences are needed for other clinical indications.
- Published
- 2017
7. Update on the safety of second generation antipsychotics in youths: a call for collaboration among paediatricians and child psychiatrists
- Author
-
Maria Pia Riccio, Annarita Milone, Massimo Molteni, Giangennaro Coppola, Stefania Veltri, Gennaro Catone, Valentina Lanzara, Gabriele Masi, Carmela Bravaccio, Emilio Clementi, Raffaella Iuliano, Sonia Radice, Antonella Gritti, Annalisa Capuano, Marco Pozzi, Simone Pisano, Pisano, Simone, Catone, Gennaro, Veltri, Stefania, Lanzara, Valentina, Pozzi, Marco, Clementi, Emilio, Iuliano, Raffaella, Riccio, Maria Pia, Radice, Sonia, Molteni, Massimo, Capuano, Annalisa, Gritti, Antonella, Coppola, Giangennaro, Milone, Annarita, Bravaccio, Carmela, and Masi, Gabriele
- Subjects
Adverse event ,medicine.medical_specialty ,Adolescent ,Early detection ,Review ,Adolescents ,Weight Gain ,Lower risk ,Off-label use ,Antipsychotic ,03 medical and health sciences ,0302 clinical medicine ,Basal Ganglia Diseases ,Risk Factors ,SAFER ,medicine ,Antipsychotics ,Humans ,Medical prescription ,Child ,Psychiatry ,Adverse effect ,Children ,Dyslipidemias ,Child psychiatrists ,business.industry ,Active monitoring ,Off-Label Use ,030227 psychiatry ,Long QT Syndrome ,Diabetes Mellitus, Type 2 ,Adverse events ,Pediatrics, Perinatology and Child Health ,Practice Guidelines as Topic ,Drug Monitoring ,business ,030217 neurology & neurosurgery ,Antipsychotic Agents - Abstract
During the past decade, a substantial increase in the use of second generation antipsychotics (SGAs) has occurred for a number of juvenile psychiatric disorders, often as off-label prescriptions. Although they were thought to be safer than older, first generation antipsychotics, mainly due to a lower risk of neurological adverse reactions, recent studies have raised significant concerns regarding their safety regarding metabolic, endocrinological and cardiovascular side effects. Aim of this paper is to update with a narrative review, the latest findings on safety of SGAs in youths. Results suggest that different SGAs may present different safety profiles. Metabolic adverse events are the most frequent and troublesome, with increasing evidences of heightened risk for type II diabetes mellitus. Results are discussed with specific emphasis on possible strategies of an active monitoring, which could enable both paediatricians and child psychiatrists to a possible prevention, early detection, and a timely management of such effects.
- Published
- 2016
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.