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A recent study conducted at Nigde Omer Halisdemir University focused on predicting the prognosis of early-stage Mycosis Fungoides using machine learning algorithms. The research aimed to compare the predictive capabilities of various algorithms in assessing progression, treatment response, and relapse in patients with early-stage MF. Results indicated that machine learning algorithms, such as Support Vector Machine and Ensemble models, showed promise in predicting prognosis, potentially offering valuable insights for patient care. The study highlights the potential of artificial intelligence in enhancing prognostic assessments for individuals with Mycosis Fungoides. [Extracted from the article]

A recent study conducted by researchers at Kyowa Kirin Inc. focused on Sezary syndrome, a rare leukemic cutaneous T cell lymphoma. The study examined real-world treatment patterns among patients with Sezary syndrome in the United States from 2018 to 2020. The research found that while some systemic therapies for Sezary syndrome decreased in usage over time, the utilization of mogamulizumab increased significantly, becoming the most commonly used systemic treatment in 2020. Treatment patterns varied by region, highlighting the need for further research to understand the factors influencing treatment selection for patients with Sezary syndrome. [Extracted from the article]

Researchers at ATTIKON University Hospital in Chaidari, Greece, have reported findings on Sezary Syndrome, a type of cutaneous T-cell lymphoma. The study focused on a 66-year-old woman with Sezary Syndrome who presented with progressive peripheral neuropathy, emphasizing the importance of thorough evaluation and consideration of clinical signs in patients with neuropathy and a history of hematologic malignancy. Early recognition and management were highlighted as crucial in shaping the clinical course of the disease. The research has been peer-reviewed and published in Neurology. [Extracted from the article]

A recent study conducted at Memorial Sloan-Kettering Cancer Center in New York City focused on a 70-year-old African American woman with mycosis fungoides, vitiligo, and a new hand nodule. The research revealed that the nodule was diagnosed as an eccrine porocarcinoma (EPC) and highlighted the importance of considering EPCs in patients with extensive skin treatments and immunosuppression history. The study was supported by the National Institutes of Health and the National Cancer Institute Cancer Center Support, and the findings were published in the International Journal of Dermatology. [Extracted from the article]

A recent report from Army Hospital Research and Referral in Delhi, India, discusses a rare case of mycosis fungoides with leukaemic involvement in middle childhood. The patient presented with non-specific folliculotropic manifestations, leading to a delayed diagnosis of MF. Treatment included a matched sibling allogeneic transplant after topical steroids and skin electron beam therapy. This research highlights the challenges of diagnosing and treating rare forms of cutaneous lymphoma in pediatric patients. [Extracted from the article]

A recent report from Sichuan University in Chengdu, People's Republic of China, discusses advancements in the diagnosis and treatment of mycosis fungoides with large cell transformation, a type of non-Hodgkin lymphoma. The research highlights the challenges in diagnosing and treating this condition, as well as the controversies surrounding aggressive treatment. The article provides insights into the etiology, pathogenesis, clinical manifestations, diagnosis, treatment, and prognosis of mycosis fungoides with large cell transformation, offering valuable information for its management. [Extracted from the article]

The article discusses a pilot study focusing on the microbiome in cutaneous T cell lymphoma (CTCL) skin lesions before and after using CLn Skin Care Body Wash. The study aims to evaluate the impact of daily use of the body wash on the microbiota of CTCL lesions, specifically looking at reducing the abundance of S. aureus. This observational study involves patients with mycosis fungoides and is being conducted at Northwestern Memorial Hospital Dermatology. The study is not yet recruiting participants, with a planned completion date in November 2025. [Extracted from the article]

Recent studies conducted at Beaumont Hospital in Dublin, Ireland, focus on Mycosis Fungoides, a type of cutaneous T-cell lymphoma. The research highlights the impact of the disease on patients' quality of life, emphasizing the psychological challenges associated with the diagnosis. The study underscores the importance of considering the emotional well-being of patients alongside medical treatment in managing Mycosis Fungoides. This peer-reviewed research sheds light on the complexities of living with and treating this condition, offering valuable insights for healthcare professionals and patients alike. [Extracted from the article]

The article discusses a clinical trial, NCT06651203, focusing on the evaluation of the KIR3DL2 marker in flow cytometry for Sezary Syndrome diagnosis, therapeutic response, and residual disease. Cutaneous T-cell lymphomas, including Mycosis Fungoides and Sezary syndrome, are characterized by erythroderma and high numbers of circulating atypical lymphocytes. The study aims to validate KIR3DL2 as a specific marker for Sezary Syndrome and assess its reliability for blood staging and response to treatment in a multicenter study involving 11 centers. The trial includes various outcome measures related to diagnosis, therapeutic response, overall survival, and progression-free survival. [Extracted from the article]

A recent study conducted by the Ministry of Health of Russia focused on mycosis fungoides, a rare type of cancer. The study analyzed 210 cases and found that treatment options for early stages included local therapy, interferon therapy, and systemic chemotherapy, while advanced stages often required combination therapy with interferon. The research highlighted the importance of non-chemotherapeutic approaches in improving relapse-free survival rates and emphasized the need for targeted therapies in later stages of treatment. The study provides valuable insights into the clinical profile and therapeutic aspects of mycosis fungoides in Russia. [Extracted from the article]

Researchers from the David Geffen School of Medicine at UCLA have highlighted the challenges in diagnosing and treating poikilodermatous mycosis fungoides, a rare variant of cutaneous T-cell lymphoma. They presented a case of a young man with limited improvement after years of treatment with topical antifungals, steroids, and phototherapy, who showed improvement following a single session of radiation therapy. The study suggests that radiation therapy may be effective for cases of poikilodermatous mycosis fungoides that are resistant to traditional treatments, emphasizing the need for further research in this area. [Extracted from the article]

Researchers at Complutense University in Madrid, Spain, conducted a study on the health-related quality of life in patients with cutaneous T-cell lymphoma, specifically mycosis fungoides and Sezary syndrome. The study found that these conditions can significantly impact patients' quality of life, with symptoms affecting various domains such as emotions, functioning, and wellbeing. The research suggests that treatment decisions should consider individual patients' disease burden to improve their quality of life. [Extracted from the article]

A recent report from the University of Florida discusses the challenges in diagnosing mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL). The researchers used next-generation sequencing (NGS) to identify pathogenic variants in 10 MF cases, revealing eight novel mutations in genes associated with MF. The study suggests that NGS can enhance the diagnosis of MF by detecting pathogenic variants that favor a neoplastic diagnosis over an inflammatory diagnosis. Further research in this area may lead to the discovery of therapeutic targets. [Extracted from the article]

A recent study conducted at Henri Mondor University Hospital in Creteil, France, has found that pustular mycosis fungoides (MF) has a poor prognosis and is associated with shorter overall survival. The study compared the clinicopathological characteristics and outcomes of patients with pustular MF (pMF) to those with nonpustular MF (NpMF). The results showed that patients with pMF had more advanced-stage disease and a higher risk of large cell transformation (LCT) at diagnosis. The presence of histological pustules at diagnosis was associated with shorter overall survival and a higher cumulative incidence of LCT. The researchers recommend that pustules found on histology should be mentioned in MF pathology reports to prompt closer follow-up. [Extracted from the article]

A new report from Ohio State University discusses the rarity of CD20 expression in mycosis fungoides (MF), a type of cutaneous lymphoma. While CD20 expression is typically scarce in MF, isolated instances of CD20-positive MF have been documented infrequently. The report presents a unique case of CD20-positive MF in a 30-year-old man and emphasizes the need for further investigation and documentation of similar cases to understand the clinical features, prognosis, and optimal therapeutic strategies. The long-term prognosis and outcomes in patients with hypopigmented MF and CD20 positivity remain unclear, highlighting the necessity for continued research. [Extracted from the article]

A report from Heidelberg University in Germany discusses research findings on Sezary Syndrome, a type of lymphoproliferative disorder. The study focuses on the diagnosis and treatment of the syndrome, which is characterized by cell death resistance. The researchers propose an integrated approach that considers the expression of specific markers on Sezary cells and their sensitivity to cell death. They found that different treatments in vitro were able to induce cell death in the malignant T cell populations, and after three months of treatment, the cell death sensitivity was restored. This novel approach could potentially lead to better therapy stratification for Sezary Syndrome. [Extracted from the article]

A recent study conducted by researchers at the National Autonomous University of Mexico (UNAM) focuses on lymphomatoid papulosis (LyP), a type of cutaneous T-cell lymphoma. The study presents the case of a 22-year-old man with subacute dermatosis who was diagnosed with type D LyP. The researchers highlight the rarity of type D LyP in Latin-American patients and emphasize the importance of sharing these findings. The prognosis for LyP is generally good, with a 10-year survival rate of 100%. [Extracted from the article]

A clinical case report on mycosis fungoides, a form of T-cell lymphoma, was presented by researchers from the University of Miami. The report describes the case of a 64-year-old Hispanic male who presented with hardened, erythematous lesions on his trunk and upper extremities. Despite initial treatment with topical glucocorticoids and systemic retinoids, the disease progressed and involved lymph nodes, requiring aggressive chemotherapy. The report highlights the aggressive and resistant nature of mycosis fungoides in this particular case, leading to a poor prognosis. [Extracted from the article]

A study conducted at the University of Texas Southwestern Medical Center compared two different T-cell receptor-g clonality assays for diagnosing mycosis fungoides, a type of cutaneous lymphoma. The researchers found that the accuracy of the two-tube assay was slightly better than the one-tube assay, but the one-tube assay had better specificity. They also noted that changing assays on the same biopsy could result in a change of clonality interpretation, potentially affecting the diagnosis. This research provides new insights into the use of T-cell receptor assays for diagnosing mycosis fungoides. [Extracted from the article]

A case report from Airlangga University in Surabaya, Indonesia, discusses the successful treatment of a 64-year-old Indonesian woman with mycosis fungoides (MF), the most prevalent cutaneous T-cell lymphoma. The patient initially presented with itchy reddish skin and thick scales, and was misdiagnosed with psoriasis vulgaris (erythroderma) before a skin biopsy revealed MF. The patient was treated with a combination of CHOP chemotherapy, narrow band-UVB therapy, and symptomatic therapies, resulting in a favorable therapeutic response. The report emphasizes the importance of early diagnosis and treatment for better prognosis, as there is currently no cure for MF. [Extracted from the article]

A recent report from Tishreen University provides a comprehensive review of mycosis fungoides (MF), the most common type of primary cutaneous T-cell lymphoma. MF is known for its wide range of clinical manifestations that can mimic various skin disorders, making diagnosis challenging. The study focuses on the different clinical and histopathological variants of MF and their differential diagnoses. The research emphasizes the importance of recognizing these variants to improve prognosis and timely treatment. For more information, readers can contact Jacob Al-Dabbagh at Tishreen University. [Extracted from the article]

A recent report from researchers at Centro Hospitalar Universitario de Lisboa Central in Lisbon, Portugal, discusses the trichoscopic findings in folliculotropic mycosis fungoides (FMF), a type of cutaneous lymphoma. The report focuses on a case study of a 50-year-old man with FMF stage IB, describing the clinical findings and trichoscopic evaluation of his condition. The researchers suggest that trichoscopic evaluation could be useful in guiding differential diagnosis and identifying early disease. This information may be valuable for individuals conducting research on mycosis fungoides and related dermatological conditions. [Extracted from the article]

The article offers information on an atypical case of mycosis fungoides with a rare phenotype and SOCS1 mutation. Topics discussed include the diagnostic challenges due to similarities with benign skin disorders; the unique blastic morphology and cytotoxic phenotype of the T-cell lymphoma; and the identification of a likely pathogenic SOCS1 mutation and STAT3 variant through next-generation sequencing.

Researchers at Thomas Jefferson University in Philadelphia have reported on a case of coexistence between large cell transformed mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL) in one patient. The patient, an 81-year-old female, presented with a tumor on her leg and lymphadenopathy in her right axilla. Skin biopsy revealed large atypical CD3+, CD4+, and CD30+ cells consistent with LCT MF, while biopsy of the lymph node revealed diffuse sheets of CD20+, BCL-2+, c-MYC+, and CD10- cells suggestive of double expressor DLBCL. The case highlights the importance of a full pathological workup in cutaneous T-cell lymphoma patients with lymphadenopathy. [Extracted from the article]

A study conducted by researchers at New York University (NYU) examined front-line treatments and quality of life in patients with newly diagnosed mycosis fungoides (MF), a type of cutaneous lymphoma. The study found that the most common first-line therapy was skin-directed therapy (SDT), while a smaller percentage received systemic therapy. The use of systemic therapy was significantly associated with higher clinical stage, presence of plaques, higher severity assessment, and folliculotropic MF. The overall response rate to SDT was higher than that of systemic treatments, and health-related quality of life improved in patients with responsive or stable disease. The researchers concluded that future treatment guidelines for early-stage MF should address these issues. [Extracted from the article]

A study conducted at Ryhov County Hospital in Jonkoping, Sweden, examined the prognostic value of histopathological features in early-stage mycosis fungoides (MF), a type of cutaneous lymphoma. The study analyzed histopathological parameters such as lymphocyte infiltrate, Pautrier microabscesses, and lymphocyte atypia in 83 MF patients. The findings suggested that patients with certain histopathological features, such as a high count of lymphocytes and atypical lymphocytes, had worse overall and progression-free survival. The study identified potential prognostic factors that could guide tailored therapeutic approaches for MF patients, but further research is needed to confirm these findings. [Extracted from the article]

A recent study conducted by researchers at the University of Copenhagen in Denmark has found that patients with Sezary Syndrome (SS), a type of cutaneous T-cell lymphoma, are susceptible to Staphylococcus aureus infections and have poor treatment outcomes due to drug resistance. The study discovered that Staphylococcus aureus and its toxins induce drug resistance in malignant T cells, making them less responsive to commonly used therapies. The findings suggest that antibacterial measures may improve the effectiveness of cancer-directed therapy in patients with SS who harbor Staphylococcus aureus. [Extracted from the article]

A recent study conducted by researchers from the University of Gothenburg in Sweden explored the epidemiology, clinical features, and treatment patterns of Sezary syndrome (SS), a rare primary cutaneous T-cell lymphoma variant. The study found that SS remains incurable with a poor prognosis, and there is a need for personalized diagnostic approaches due to the variability in symptoms at diagnosis. The median survival for patients with SS was only 2.1 years, highlighting the aggressive nature of the disease. Combination therapy, specifically triple therapy involving retinoids, interferon alpha, and extracorporeal photopheresis (ECP), showed the longest median time to next treatment (TTNT). Early initiation of ECP treatment did not result in improved outcomes. The study emphasizes the importance of combination therapy and the need for further research to identify optimal treatment approaches. [Extracted from the article]

A recent study conducted at University Hospital 12 Octubre in Madrid, Spain, explored the use of pegylated interferon A-2a (PEG-IFN-alpha-2a) as a treatment for mycosis fungoides (MF) and Sezary syndrome (SS), which are chronic malignant diseases. The study included 105 patients from 10 countries and found that combination treatment with PEG-IFN-alpha-2a resulted in a longer time to next treatment (TTNT) compared to monotherapy. The overall response rate (ORR) was 53.3%, with a complete response seen in 13% of patients and a partial response in 40%. Adverse events were reported in 68.6% of patients, with flu-like symptoms, lymphopenia, and elevated liver function being the most common. The study concluded that combination regimens and higher doses of PEG-IFN-alpha-2a were associated with a higher ORR. [Extracted from the article]

A new report discusses research findings on lymphomatoid papulosis (LyP), a rare cutaneous T-cell lymphoproliferative disorder. The study involved 87 children and adolescents with LyP and aimed to characterize the epidemiological, clinical, histopathological, and prognostic features of pediatric LyP. The study found that LyP in children presents similarly to adults and has a good prognosis with excellent survival rates. However, long-term follow-up is recommended due to an increased risk of associated hematological malignancy. Treatment options are available, and the disease requires monitoring by a dermatologist. [Extracted from the article]

A recent study conducted by researchers at Public Assistance - Paris Hospitals (AP-HP) focused on Sezary syndrome, a subtype of cutaneous T-cell lymphoma (CTCL). The study examined the case of a 62-year-old female patient who developed Sezary syndrome while undergoing atezolizumab treatment for tumor-stage transformed mycosis fungoides (MF). Despite various treatments, including oral drugs and radiation therapy, the patient's condition did not improve. The researchers concluded that the emergence of Sezary syndrome during atezolizumab treatment highlights the potential risks and complexities of using PD-L1 inhibitors for CTCL treatment. [Extracted from the article]

A recent study conducted at the University of Pittsburgh has shed light on the cellular origin and differentiation trajectories of cutaneous T-cell lymphomas, specifically mycosis fungoides (MF) and Sézary syndrome (SS). The researchers used TCR sequencing and targeted transcriptomics to analyze single-cell samples from MF and SS patients. The findings revealed distinct populations of CD4+ T cells in SS compared to MF, as well as different subsets of malignant cells within SS. These findings provide valuable insights into the relationship between MF and SS and may contribute to the development of more effective therapeutic strategies. [Extracted from the article]

A recent study conducted at the University of Milan in Italy focused on mycosis fungoides (MF), a type of cutaneous lymphoma. The researchers examined two cases of epidermotropic T-cell lymphoma with an MF-like clinical pattern and ALK expression and molecular alteration. They found that ALK+ primary cutaneous T-cell lymphomas (pcTCL) are rare and can present with a broader range of disease patterns, including those that mimic MF and primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma. The study suggests that targeted therapy may be an option for advanced stages of ALK+ pcTCL, based on ALK expression. However, more research is needed to determine the optimal management approach. [Extracted from the article]

Researchers from Autonomous University in Madrid, Spain have published a report on a distinctive presentation of Mycosis Fungoides (MF), a type of cutaneous lymphoma. The report highlights two cases of MF with clinical urticarial lesions and blood involvement that responded to mogamulizumab treatment. The researchers emphasize the importance of histopathology in diagnosing atypical presentations of MF and note that a low suspicion threshold is necessary for accurate diagnosis. This research has been peer-reviewed and published in the Journal of Cutaneous Pathology. [Extracted from the article]

Researchers at the University of Virginia have discussed new data on mycosis fungoides, the most common type of primary cutaneous T-cell lymphoma. They emphasize the importance of recognizing variants of mycosis fungoides with different immunophenotypes to ensure accurate diagnosis and appropriate management. The researchers present a case of a 49-year-old male with an unusual NK/T-cell phenotype and describe the diagnostic challenges posed by null T-cell phenotype mycosis fungoides with aberrant expression of CD56 and CD20. They conclude that this variant is rare, diagnostically challenging, and can lead to misdiagnosis of aggressive lymphoma subtypes. [Extracted from the article]

A new report from researchers at Memorial Sloan-Kettering Cancer Center in New York City highlights racial disparities in mycosis fungoides/Sezary syndrome, a type of cutaneous lymphoma. The study found that black patients had worse survival outcomes compared to white patients, with different survival risks associated with hypopigmentation, erythroderma, and ulceration between the races. The researchers suggest that further investigation is needed to understand the underlying mechanisms and potential impact on treatment strategies. This study provides valuable insights into the differences in clinical presentation and outcomes based on race in patients with mycosis fungoides/Sezary syndrome. [Extracted from the article]

Researchers at the Department of Dermatology have described a rare case of mycosis fungoides, a type of cutaneous T-cell lymphoma, initially misdiagnosed as pigmented purpura. The patient, a 44-year-old woman, developed a skin condition on the base of her left thumb. The distinct characteristics of the rash, including discrete patches with colored dots and progressive thickening and pigmentation, prompted further investigation and led to the correct diagnosis. The patient's treatment involved a combination of steroids and narrowband UV therapy. This case highlights the importance of accurately diagnosing uncommon dermatological disorders to ensure appropriate medical intervention. [Extracted from the article]

Researchers at Harvard Medical School have conducted a retrospective cohort study to evaluate adherence to guidelines for mycosis fungoides and Sezary syndrome clinical trials. The study found that mean adherence to the guidelines was approximately 60% among the included trials. However, there was no significant difference in adherence between trials that began in the first 6 years after the publication of the guidelines and those that started after. Pivotal trials supporting new therapies were more likely to implement the recommendations. The findings suggest that the guidelines are not consistently implemented across all trials. [Extracted from the article]

A recent study from the University of Florence School of Medicine explores the treatment options for mycosis fungoides, the most common type of cutaneous T-cell lymphoma. The study highlights the multiphasic nature of the disease, with early stages being less aggressive and later stages progressing more rapidly. The researchers discuss the use of skin-directed therapies and biologic response modifiers in the early stages, and radiotherapy and systemic therapies in the later stages. The paper emphasizes the lack of a universally accepted approach to treatment and provides a comprehensive review of the available options. [Extracted from the article]

A recent report from researchers at Galliera Hospital discusses the use of radiation therapy in the treatment of mycosis fungoides, a type of cutaneous lymphoma. The researchers highlight the various techniques and indications for radiation therapy in these patients, emphasizing its effectiveness in improving quality of life and treatment outcomes. They suggest that a multidisciplinary approach and understanding of current methods and mechanisms of action can encourage the use of radiation therapy as a skin-directed therapy. For more information, readers can refer to the article "Radiation therapy in mycosis fungoides" published in Dermatology Reports. [Extracted from the article]

A recent study conducted by researchers at the San Gallicano Dermatological Institute IRCCS focused on mycosis fungoides, the most common primary cutaneous T-cell lymphoma. The disease is characterized by the development of plaques and nodules after an initial non-specific phase. The researchers emphasized the challenges in diagnosing mycosis fungoides early due to its ability to mimic other skin disorders. They recommended multiple biopsies and careful correlation of clinical and pathological findings for a conclusive diagnosis. The study also discussed the various variations of mycosis fungoides and its benign mimics. [Extracted from the article]

A recent study conducted in Ankara, Turkey, investigated the potential role of the C-reactive protein to albumin ratio (CAR) as a diagnostic and prognostic indicator in mycosis fungoides (MF), a type of cutaneous lymphoma. The study analyzed the electronic medical records of 97 MF patients and found that the CAR was significantly higher in MF patients compared to the control group. However, the CAR did not have prognostic significance in terms of disease progression. The researchers suggest that the CAR could be a useful tool in diagnosing MF when faced with difficulties. [Extracted from the article]

A clinical trial, NCT06382844, has been initiated to enhance the detection and measurement of tumor cells in patients with cutaneous T-cell lymphoma (CTCL). The current flow cytometry techniques used in clinical laboratories do not allow for accurate comparison of results in a clinical setting. The project aims to apply standardized strategies of next-generation flow cytometry to detect and quantify tumor cells in CTCL patients. The study will involve developing optimal marker combinations, evaluating the specificity and sensitivity of the new procedure, creating reference databases for automated analysis of cytometry data, and validating the method in multiple centers. Additionally, the project will explore the relationship between the tumor microenvironment and the clinical-biological heterogeneity of the tumor. A new standardized flow cytometry strategy has been developed to detect and measure circulating tumor cells in CTCL patients, with the goal of supporting dermo-hematological diagnosis and improving the accuracy of early diagnosis and treatment response assessment. The study is currently enrolling CTCL patients and is expected to be completed by December 2026. The research is being conducted in Spain through a collaboration between the Instituto de Investigacion Biomedica de Salamanca and the Carlos III Health Institute. [Extracted from the article]

A recent research report from King Saud University and King Saud University Medical City provides new insights into mycosis fungoides, the predominant form of primary cutaneous T-cell lymphoma. The report highlights the rare occurrence of the CD4-/CD8- double-negative variant of mycosis fungoides, which is observed in approximately 12% of early-stage cases and more prevalent in tumor-stage instances. The researchers aim to enhance clarity and comprehension of this variant through a detailed exploration of its spectrum. This information is valuable for individuals conducting research on cancer, dermatology, and lymphoproliferative disorders. [Extracted from the article]

This article presents the interim findings of a study sponsored by Kyowa Kirin, Inc. The study, called "Real-World Observational Study of Mogamulizumab in Adult Patients with Mycosis Fungoides and Sezary Syndrome (PROSPER)," aims to evaluate the impact of mogamulizumab on disease symptoms and quality of life in patients with cutaneous T-cell lymphoma (CTCL). CTCL is a rare form of non-Hodgkin lymphoma that primarily affects the skin and can cause severe itching. The study found that within four weeks of treatment initiation, patients reported improvement in all symptoms, including skin itch, redness, flaking, and pain. The study suggests that mogamulizumab may have a positive impact on patients' symptoms and quality of life. [Extracted from the article]

A recent study conducted by researchers at Oxford University Hospitals NHS Foundation Trust in the United Kingdom focused on mycosis fungoides, a type of cutaneous lymphoma, in pediatric patients. The study found that diagnosing these diseases in children can be challenging due to their clinical and pathological heterogeneity. The researchers emphasized the importance of providing age-appropriate patient information and psychological support, as well as the need for further long-term data and guidance on management. The study presented clinical outcomes for a cohort of five pediatric patients with mycosis fungoides and discussed the combined approach of clinical expertise and psychological support in a dermatology pediatric service. [Extracted from the article]

A recent report from University Hospital in Yvoir, Belgium describes a case of mycosis fungoides, a type of cutaneous T-cell lymphoma, presenting as perichondritis of the pinna in a 78-year-old patient. The patient experienced progressive necrosis of the pinna, requiring surgical management. The final anatomopathological analysis confirmed mycosis fungoides, which had transformed into a large T-cell lymphoma. This case highlights the rarity and potential aggressiveness of mycosis fungoides in the pinna, its ability to mimic perichondritis, and provides visual documentation of the condition. For more information, refer to the article "Perichondritis As a Presentation of Mycosis Fungoides Infiltrating the Pinna" in the journal B-ENT. [Extracted from the article]