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This article is devoted to the study of collagen-containing raw materials and obtained collagen substances. Histomorphological analysis was carried out, which resulted in data on the presence of collagen in animal and fish raw materials, but characterized by a loose structure and a smaller thickness of fibers in the case of fish skins. Studies of the fractional composition showed that the predominant fraction is alkali-soluble, which include collagen proteins. The obtained dispersion of collagen fibers of the hides of inland water bodies and split leather from cattle hides. Dispersions are similar in properties, but have some differences associated with structural features. The materials obtained for the food, cosmetic and medical industries meet the principles of rational nature management and are economically viable.New ideas about the role of collagen in nutrition, the creation of original products, the need to develop unconventional and improve existing technologies of collagen substances of various functionalities, require the implementation of approaches to ensure maximum transformation of collagen-containing resources into human products, materials and tools.New ideas about the role of collagen in nutrition, the creation of original products, the need to develop unconventional and improve existing technologies of collagen substances of various functionalities, require the implementation of approaches to ensure maximum transformation of collagen-containing resources into human products, materials and tools.In terms of sanctions of the European Union, the United States and supporters, reducing the import of natural polymer-film coatings, finding new sources of film coatings for the food surface is most appropriate.

China is one of the leading suppliers of fish and seafood to Russia. A strong example is tilapia fish. This relatively inexpensive fish, due to the small amount of its cultivation in the Russian Federation, is completely imported from China. However, at present, the lack of an adequate level of control over the movement of raw materials through production chains and their processing at Chinese enterprises, the import of tilapia is temporarily stopped. In this regard, a comparative assessment of the quality of tilapia grown under aquaculture conditions in Russia and China at all stages of industrial processing is relevant. In order to assess the quality of fish raw materials, a multisensory system “electronic nose” was used, which is based on a multilevel neural semiotic model that describes the mechanism of the human olfactory bulb. The use of chemical sensors allowed recording early signs of changes in the organoleptic parameters of tilapia meat. The studies showed that the meat of tilapia grown in Russia is subject to less destruction during storage at a temperature of 4 ° C than meat of tilapia grown under the agricultural conditions in China.

In the process of life of the body continuously consumed nutrients that perform plastic and energy functions. The source of nutrients is a variety of foods, consisting of a complex of proteins, fats and carbohydrates, which in the process of digestion are converted into digestible substances. Collagen is the basis of connective tissue and binds the cells in the tissues, creates the frame of the whole body. The gastrointestinal tract, as a system of organs, is no exception and is designed process and extract nutrients from food. Most organs consist of connective tissue, accounting for 60–90% of their mass, which confirms its importance and the role of collagen in this regard can not be estimated. Collagen functions in the body are diverse, one of the main - part in digestion, the violation of which is the cause of diseases such as gastritis and ulcers. For the prevention and treatment of such diseases are very useful liquid collagen-containing food in the form of functional drinks. Developed and obtained in the experimental laboratory a variety of drinks on a collagen basis, with the use of additional broth with sea buckthorn pulp, tincture of dried chicory root powder and broth with the flesh of Jerusalem artichoke. An invaluable contribution to the therapeutic and preventive actions of all these components is proved not only scientifically, but also time-tested.

Purposeful use of proteins of connecting fabrics is based first of all on structural and mechanical and physical and chemical properties of collagen, his physiology to a human body. Traditional source of collagen is the split of skins of the cattle, but in view of the objective reasons (spongy encephalopathy, reduction of a livestock of cattle), there was a need for search of alternative sources. The particular interest and popularity represent collagenic proteins in biomedical technologies, when receiving surgical sutural materials, wound healing means, prolongator of medicines, artificial organs and fabrics, implatant. New data on use the collagen containing of sources are directly connected with expansion of a source of raw materials of processing industries of agrarian and industrial complex on the basis of deep processing of biological resources and their maximum involvement in the main and special production with significant growth in an exit of useful products from raw materials unit. In this regard, researches of a microstructure of skins and fractional composition of proteins of objects of research are conducted; data on the general chemical composition and the content of collagen in them are received. Experimental data showed that the most perspective source of collagen from the studied fishes of internal reservoirs is the skin of a silver carp that is caused by the high content of target substance collagen, the low content of fat. The technology of receiving collagenic substances with the high technical characteristics allowing to apply them in production of medical materials is proved and realized in vitro. The comparative analysis showed that substances from a split of skins of cattle and a silver carp have an identical set of amino acids, but are characterized by the different content of separate amino acid s.

Process of sorption of iodine on the collagenic carrier is studied. Duration of binding and optimum amount of iodide of potassium, sorption capacity of the preparation PROMIL C95 respect of Iis determined.

In the treatment of tissue wounds practically all the time there is necessary the establishment of aseptic conditions in the area of the damaged tissue. In modern medical practice quite a while the use of materials on the basis of collagen aroused widespread. The aim of the study was an assessment the bacteriostatic properties both of collagenic substance with the antibiotics immobilized on it, and ions of silver also. The presence on a surface of collagen of a large number of active functional groups allow to use it as a matrix for an immobilization of various biologically active and medicinal agents. Authors performed an assessment of possibility of an immobilization of antibiotics on the collagenic carrier. The purpose of an immobilization was in the prolongation of the impact of an active component--Polymyxin-M or Gentamycin. Besides aseptic effect, availability of specific amino acids of collagen will promote the acceleration of the reparative processes in a wound. There were performed investigations on determination of bacteriostatic effect of immobilized on the protein carrier (collagen of hydrobionts) antibiotics, and silver ions also. Bacteriostatic effect was estimated by the disco--a diffusive method with use of E. coli as test culture. Results of the studies showed that the delivered preparation had bacteriostatic effect on the test culture. At that the area of a zone of a growth inhibition in case of the of use--Polymyxin was 1.3 time more than, than in case of the use of a preparation of Gentamycin. The obtained collagenic substances of an origin with the immobilized bacteriostatic components and ions of silver have considerable prospects and real opportunity in the delivery of aseptic preparations of a domestic production. Taking into account the available data in further there is planned the development of aseptic preparations with the occluded biologically active agents and nanoparticles of metals for providing an aseptics and acceleration the reparative processes in the treatment of open wounds.

Development of theoretical and practical bases of technology of biocompatible materials of a domestic production on the basis of the natural polymeric systems allocated from raw materials of an animal, fish and a phytogenesis is actual in interests of development of science, health care, ecology. Now practically there are no domestic materials on the basis of products of modification of biopolymers for production of biocompatible materials with adjustable physical and chemical and biological properties. In this regard the special importance is gained by works on studying of functional properties of natural biopolymers, in particular collagen, elastin, hyaluronic acid. Interest of researchers to biopolymers of the proteinaceous nature is quite reasonable as they possess sufficient permeability, a big specific surface and sorption capacity, possibility of receiving convenient in technological forms, a low immunogenicity, possibility of regulation лизиса. Data on possible ways of use are presented in article secondary the collagenic wastes - skins of fishes of internal reservoirs of Russia. Innovative processing methods of processing of secondary raw materials with receiving functional biopolymers of a wide range of application are developed. With application of modern methods of researches their characteristics and property are defined. On a complex of organoleptic, physical and chemical indicators, indexes of biological activity the received preparations hyaluronic acid and collagen can find broad application in medicine, cosmetology. The resource-saving technology of receiving tanning semi-finished products easily giving in to further processing for the purpose of receiving leather haberdashery and textile production is developed. Thus, scientific new approaches in processing of skins of pond fishes on the basis of their deep processing are proved.

The chemical composition and functional and technological properties of meat of a silver carp and milts of a spoon-billed cat American were investigated. The compounding was developed and the technology of fish paste with their use was adapted.

The article presents data on the study of alimentary correcting properties of the functional iodine fortified meat products.