467 results on '"Sica, Filomena"'
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2. Ordered hierarchical superlattice amplifies coated-CeO2 nanoparticles luminescence
3. Tailoring the stress response of human skin cells by substantially limiting the nuclear localization of angiogenin
4. Aptamers: Functional-Structural Studies and Biomedical Applications 2.0
5. Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12
6. Structural Insights into Protein–Aptamer Recognitions Emerged from Experimental and Computational Studies
7. On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer.
8. New insight into the traditional model of the coagulation cascade and its regulation: illustrated review of a three-dimensional view
9. Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide
10. Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study
11. Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry
12. A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers
13. Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases
14. Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability
15. High yield purification and first structural characterization of the full‐length bacterial toxin CNF1
16. Aptamers: Functional-Structural Studies and Biomedical Applications
17. Effect of NaCl on the conformational stability of the thermophilic γ-glutamyltranspeptidase from Geobacillus thermodenitrificans: Implication for globular protein halotolerance
18. Exploring the unfolding mechanism of γ-glutamyltranspeptidases: The case of the thermophilic enzyme from Geobacillus thermodenitrificans
19. Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands
20. The structural features of an ancient ribonuclease from Salmo salar reveal an intriguing case of auto-inhibition
21. The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins
22. Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin
23. Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly) 10
24. Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer
25. Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy
26. Monitoring Preparation of Derivative Protein Crystals via Raman Microscopy
27. High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity
28. Thrombin–aptamer recognition: a revealed ambiguity
29. A novel ErbB2 epitope targeted by human antitumor immunoagents
30. Structure–Activity Relationship Study of a Potent α‐Thrombin Binding Aptamer Incorporating Hexitol Nucleotides
31. Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites
32. Structural motifs determining the high anti-thrombin activity of NU172, an aptamer currently in Phase II clinical trials
33. Structural features of a duplex-quadruplex anti-thrombin aptamer: the highly effective NU172
34. Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant
35. Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent
36. Understanding the binding properties of an unusual metal-binding protein – a study of bacterial frataxin
37. Structural basis for the recognition of human alpha-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials
38. Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites.
39. Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer
40. Structural Evidences of the Long Range Cross-talk between the two Exosites of Human α-Thrombin
41. A RAMAN/SANS/XRD STUDY ON THE STRUCTURE-PROPERTY RELATIONSHIP OF OUTDOOR AND INDOOR ROMAN WALL PAINTINGS
42. BINDING PROPERTIES OF APTAMERS WITH MIXED STRUCTURE: ROLE OF THE DUPLEX/QUADRUPLEX JUNCTION
43. Peculiar structural features of NU172: the only thrombin binding aptamer currently in phase II clinical trials
44. Structural Elucidation of Binary and Ternary Complexes of Thrombin with DNA-Aptamers
45. Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers
46. High yield purification and first structural characterization of the full-length bacterial toxin CNF1
47. Free-energy profile for CO binding to separated chains of human and Trematomus newnesi hemoglobin: insights from molecular dynamics simulations and perturbed matrix method
48. Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures
49. Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers
50. 3D domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase
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