1. Genetic variants associated with cardiac structure and function
- Author
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Vasan, Ramachandran S., Glazer, Nicole L., Felix, Janine F., Lieb, Wolfgang, Wild, Philipp S., Felix, Stephan B, Watzinger, Norbert, Larson, Martin G., Smith, Nicholas L., Dehghan, Abbas, Gro-henning, Anika, Schillert, Arne, Teumer, Alexander, Schmidt, Reinhold, Kathiresan, Sekar, Lumley, Thomas, Aulchenko, Yurii S., Konig, Inke R., Zeller, Tanja, Homuth, Georg, Struchalin, Maksim, Aragam, Jayashri, Bis, Joshua C., Rivadeneira, Fernando, Erdmann, Jeanette, Schnabel, Renate B., Dorr, Marcus, Zweiker, Robert, Lind Lars, Rodeheffer, Richard J., Greiser, Karin Halina, Levy, Daniel, Haritunians, Talin, Deckers, Jaap W., Stritzke, Jan, Lackner, Karl J., Volker, Uwe, Ingelsson, Erik, Kullo, Iftikhar, Haerting, Johannes, OEDonnell, Christopher J., Heckbert, Susan R., Stricker, Bruno H., Ziegler, Andreas, Reffelmann, Thorsten, Redfield, Margaret M., Werdan, Karl, Mitchell, Gary F., Rice, Kenneth, Arnett, Donna K., Hofman, Albert, Gottdiener, John S., Uitterlinden, Andre G., Meitinger, Thomas, Blettner, Maria, Friedrich, Nele, Wang, Thomas J., Psaty, Bruce M., van Duijn, Cornelia M., Wichmann, H.-Erich, Munzel, Thomas F., Kroemer, Heyo K., Benjamin, Emelia J., Rotter, Jerome I., Witteman, Jacqueline C., Schunkert, Heribert, Schmidt, Helena, Volzke, Henry, and Blankenberg, Stefan
- Subjects
Cardiovascular diseases -- Genetic aspects ,Echocardiography -- Usage ,Heart -- Physiological aspects ,Heart -- Genetic aspects ,Meta-analysis -- Usage - Abstract
A study was conducted to investigate and identify genetic variants that are associated with cardiac structure and function through a meta-analysis. Results indicated that there were 5 genetic loci, associated with variance in cardiac dimensions and aortic root size; however, the proportion of variance is quite small.
- Published
- 2009