Search

Introduction. Recent studies carried out in the permanent dentition revealed a wide range of terminal relationships between enamel and cement described by Choquet, characterized by not having a unique pattern around the tooth neck. This is little studied in the primary dentition. Objective. To know the frequency distribution of the cemento-enamel junction in the temporary dental organs. Methodology. In a study approved by the Research and Ethics Commission of the Faculty of Stomatology of the BUAP (registration 2019104) a probabilistic, non-random sample, stratified by sex, of 73 healthy dental organs was analyzed, with more than one third of root and any dental formula of children between three and five years of age. They were observed under an optical microscope at magnifications of 5, 10 and 20x, slices obtained with the wear technique. Microphotographs obtained with a camera integrated to the microscope were analyzed by an observer (k = .9102). Results. 180 sections were obtained from the calculated sample. The percentage distribution of the cases corresponds case 1, 41%; case 2 present in 13%; case 3, 38%; and case 4, eight percent. According to the anatomic faces, case 1 was more frequent in the mesio-vestibular face (37%), case 2 in the mesio-lingual/palatal (44%), case 3 in 35% of the mesio-vestibular faces, and case 4 in 72% of the mesio-vestibular faces. Discussion. The tissue relations between the enamel and cement of the temporary dentition present the four combinations reported by Choquet in a different frequency distribution with respect to the authors consulted. Interdigitations between cementum and enamel of the primary dentition were observed, as well as serendipiti; some sui generis characteristics in the underlying dentin. [ABSTRACT FROM AUTHOR]

Introduction. Little literature has been reported about the forms that characterize caries lesions according to their destructive advancement of dental tissues, so it is necessary to describe the characteristics of the lesions in each of the stages of advancement and match them with the observations clinics, in such a way that the radiographic image is complemented, because the latter has serious limitations in incipient lesions. Objective. Describe the characteristics of caries lesions according to the progress of the destructive process of dental hard tissues. Methodology. In a descriptive, observational, cross-sectional, prospective, heterodemic and single-center study, a sample of 30 specimens of donated temporary dental organs, preserved in formalin and cut at 1 mm thickness was analyzed to be observed under different types of microscope to describe the variables: caries lesion shape, penetration, color and characteristics of the lesions surface at each stage of advancement; according to the independent variable ICDAS caries diagnostic code. Results. The ICDAS 0 code does not present tissue alterations. ICDAS 1 presents superficial erosion; ICDAS 2 all enamel affected with loss of dentin tufts, has a cylindrical shape, dull white color; ICDAS 3 all demineralized enamel, cylindrical shape, greyish white; ICDAS 4 undermined enamel without dentin support with affected dentin tubules; ICDAS 5 total enamel loss; 40% affects deep dentin, brown conical shape; ICDAS 6 total destruction of enamel, totally affected dentin, 40% black color. Conclusions. Histological images complement the clinical appearance of caries lesions according to their progress. [ABSTRACT FROM AUTHOR]

Introduction. It is considered that in the temporomandibular joint of children, the glenoid cavity is almost flat with a low prominence of the anterior or temporal condyle that allows the anterior displacement of the jaw, so that the incisors cross over is smaller and it is considered that there is no Spee curve, and its analysis is lacking. Objective. To analyze the frequency and risk association of the presence of the Spee curve in each of the terminal planes and the overbite. Material and method. In a cross-sectional, prospective and analytical clinical epidemiological study, a heterodemic and multicentric probabilistic sample stratified by sex was analyzed, from 140 sets of temporary dentition models of the child population aged 3 to 5 years, without loss of proximal walls or cavitations for caries, as well as with fractured dental organs. Were analyzed the dependent variables Spee curve, terminal plane and overbite. Results. Were tested the hypothesis of dependence of the Spee curve with respect to the type of terminal plane (c2 = 7.104, p = 0.01, Gl = 1). The prevalence rate of the presence of the Spee curve was 43.47%. Its association with the straight terminal plane is RM = 3.96 and with the deep bite it is RM = 2.89. Conclusions. The curve of Spee is present in the deciduous dentition and responds to the need to compensate the condylar trajectory that promotes the maximum intercuspidization that allows protrusive de-occlusion thanks to the anterior and condylar guides that avoid excessive pressure in the posterior area, optimizes the incisive function during the cutting action and promotes the wear of cusps and incisal edges, which is why deep bites were not found. [ABSTRACT FROM AUTHOR]

Introduction. The cervical vestibule ridge is an anatomical feature of primary molars that lack a socket in the cervical region. It has the function of a structural element in the shape of a flying buttress located on the external part corresponding to the dental crown whose function is the distribution of occlusion loads. Objective. To describe the frequency distribution of the enamel-cement tissue relations of the vestibulocervical crest of primary molars and their behavior in the mechanics of occlusion forces in the area. Methodology. In an observational, descriptive, cross-sectional, prospective study, a probabilistic, non-random sample, stratified by sex (n = 73), of healthy temporary dental organs with roots, of the child population of the state of Puebla was analyzed, aged between 3 and 5 years old. They were preserved in formalin and 36 sections of 0.5 mm thickness were obtained from the vestibulocervical crest area that were analyzed at magnifications of 5, 10 and 20x by an only one observer (k = .9102). Results. Forty-two percent of the sample was Choquet type 3 cases, 28% type 2 and 22% type 1 and 4, respectively. Little dentin damage was observed in the vestibulocervical area. Conclusions. The vestibulocervical crest is a transmitter of protective loads from thin, curved roots. The difference between modulus of elasticity and hardness is large, but the bulge of the enamel acts as a buttress for load distribution. [ABSTRACT FROM AUTHOR]

The demand of orthodontic treatments in the last years has increased as a result of an improvement in the dental health, a greater offer of professionals and the evolution of the cultural norms on the concept of acceptable occlusion. For that reason the experts in health have concentrated all efforts in the design and validation of objectives methods to registry and measurement of the malocclusion with the purpose of know the real necessity of treatment of the population and the benefits obtained with these treatments. Therefore this investigation will contribute to the objective evaluation of the criteria of early necessity of patients of the region of Puebla, specifically of those who assist to the clinic of orthodontics at the University of Puebla to offer them a suitable and opportune orthodontic treatment. [ABSTRACT FROM AUTHOR]

It aims to determine the level of impact of the journal ORAL in the database IMBIOMED. Retrospective and longitudinal study. Consultations and visits done to the serial publications of stomatologists in the Indice Mexicano de Revistas Biomédicas Latinoamericanas (IMBIOMED) were evaluated of a group of cibermetric indicators selected with that purpose. The magazines that most people read were determined, the magazines with most articles downloaded, the total of articles, the most famous author, among others. In order to determine the most popular magazines for stomatologist, it was developed a general index from the highest position of each one of the studied publications in the classification according individual indicators. [ABSTRACT FROM AUTHOR]

Introduction. One of the main objectives of prosthodontics is the rehabilitation and maintenance of oral function and health of edentulous patients, including people with disabilities such as patients with Down's syndrome. These patients usually present both systemic compromises and dental anomalies, resulting in difficult oral care and a commitment to your oral health, so in the most severe cases, the placement of a total prosthesis is essential and of utmost importance to reestablish the functions of the stomatognathic apparatus, optimize chewing capacity, comfort, preservation of the alveolar bone and improve the psychosocial condition of the patient. Objective. Restoring function and aesthetics in a Down's syndrome patient by placing an analogically produced total denture in combination with digital workflow. Clinical case. The clinical case of a female patient with Down's syndrome is presented, 46 years old, with bimaxillary loss of dental organs. A total prosthesis is made by using the analogical method for taking physiological impressions, making the registration bases, threading and characterizing the prosthesis, in combination with the digital workflow for scanning the impressions, making the working models and milling the characterized prosthesis. Conclusion. Due to the complexity that a prosthetic treatment represents in a patient with some type of disability, the combination of CAD-CAM technology and the analogous method in the elaboration of a total denture improves the prognosis and increases the success, there is a better adjustment and retention of these, they are more durable and tend to a lower accumulation of dentobacterial plaque. [ABSTRACT FROM AUTHOR]

Introducción: La situación de la lectura en México arroja números alarmantes y preocupantes, ya que se calcula que el 70% de los mexicanos en primaria y hasta la universidad no lee, en un estudio realizado por la CONACULTA en el año 2006 México se encuentra en el lugar número 35 en cuanto a la comprensión de lectura. Los jóvenes con el hábito de la lectura tienen mejores resultados durante su formación académica; sin embargo, actualmente, los egresados de nivel medio superior registran serias deficiencias en este ámbito. Objetivo: Determinar los hábitos de lectura de los estudiantes del área de la salud de la BUAP. Material y método: Estudio observacional descriptivo transversal donde se encuestaron 457 alumnos del área de la salud con un instrumento diseñado adhoc para el estudio. Se calculó estadística, descriptiva, media, de IC95% así como proporciones en el paquete estadístico SPSS v. 12. Resultados: Se incluyeron 273 (59.7%) mujeres y 184 (40.3%) hombres con promedio de 20.6 ± 2.0 años de edad de las cuatro facultades del área de la salud el 52.1% refirió leer por aprender, aunque el 47.5% en el tipo de lectura fueron novelas, casi el 39% refirió leer entre una y tres horas a la semana en contraste con el 46.4% que refirió ver la televisión entre una y dos horas diariamente. Conclusión: Los hábitos referidos de lectura de los estudiantes del área de la salud, denotan poco tiempo invertido en la lectura con preferencia de temas no científicos. [ABSTRACT FROM AUTHOR]

Introduction. Henoch-Schönlein purpura (PHS) described in 1875, it's multifactorial, involves previous infectious processes in the upper respiratory tract. Multiple clinical manifestations such as skin lesions, joint damage, abdominal, pulmonary, genitourinary, nephropathy, neurological and hematological. The diagnosis is made through physical examination, general examination of urine. In children, the prognosis is favorable. The stomatological exploration has to be individualized, focused on the elimination of infectious foci that can affect immunosuppressive treatment and predispose the patient to secondary infections. The use of drugs that are excreted via the kidney should be avoided and those that are excreted via the liver should be used. It is important to know that if immunosuppressants and non-steroidal anti-inflammatory drugs are used, they will produce hematological and immune changes, such as leukopenia, neutropenia, and thrombocytopenia, and will identify through laboratory studies that can help us decide if the prescription of antibiotic prophylaxis is necessary to perform oral rehabilitation. Clinical case. A 9-year-old male with PHS under observation by hematology, nephrology and rheumatology, laboratory studies showed normal parameters, so he was orally rehabilitated in two phases (hygienic-preventive and restorative-control). Stomatological management was specific according to the state of health in which he was at the time of oral rehabilitation. Conclusions. It is important to establish an interconsultation with the treating medical specialists in order to assess at all times the general systemic condition of the patient, taking into account specific stomatological considerations. [ABSTRACT FROM AUTHOR]

Introduction. Masticatory efficiency (ME) is the individual ability to achieve crushing and grinding, with the help of saliva, through an undetermined number of masticatory cycles. The maximum bite force in kilograms force (MBF/kgf) is the maximum force generated between the teeth of both arches. Objective. To relate MBF/kgf and ME in patients with and without posterior teeth (PT). Methodology. Cross-sectional, observational, and descriptive study. Forty patients who attended in the Masticatory Physiology Laboratory of the Universidad Autónoma Metropolitana-Xochimilco, Ciudad de México, who previously voluntarily they accepted informed consent, were registered; divided into two groups: group A, 20 subjects with complete PT; and group B, 20 with incomplete PT. The ME recording technique consisted of measuring the degree of crushing of silicone tablets by condensation, with a diameter of 20 mm by 5 of thick and 2.03 g, the fragments were collected to perform the sieve (Mesh). The MBF/kgf recordings were made with the T-Scan® EH-2 system, positioning the sensor between the arches, exerting the MBF for 28 sec. Results. Of the 40 subjects, 18 (45%) were female and 22 (55%) males, with a mean age of 23.88 ± 9.6 years. In group A, the MBF/kgf was 35.65 ± 10.30, and the MP was 62.51 ± 21.99. In group B, the MBF/kgf was 20.61 ± 13.45 and the MP was 47.20 ± 25.73. Conclusions. The importance of the relationship between PT in relation to MBM/kgf, and ME was observed, which showed that patients with incomplete dentures present less trituration and grinding, which can directly affect the digestive system, therefore, the need to keep the highest number of PT in the mouth was demonstrated. [ABSTRACT FROM AUTHOR]

Mutations or chromosome aberrations are considered alterations in the chromosome number or structure. They are mainly considered due to gametogenesis inborn error (meiosis) or during the zygote first cellular divisions. All these alterations might be observed during metaphase from the cellular cycle, where DNA loses are seen (clastogenic processes) due to DNA repair processes deficiency o total absence, among others. 4617 chromosomal studies were performed at Hospital Para El Niño Poblano (Pediatric Hospital) in Mexico. During 19 years period of time (from 1992 to 2011) were 34.6% (1596 patients) showed different chromosomal alterations. Among the studies population, male and female pediatric patients with different genetic diseases were chosen. These chromosome changes are classified as numeric or structural alterations, respectively. Another group of genetic alterations are known as mutations and can be inherited among generations. A wide variety of pediatric patients with genetic diseases due to chromosome aberrations are described in this study analyzing their clinical characteristics, medical or surgical treatments and their medical evolution according to the genetic disease. [ABSTRACT FROM AUTHOR]

Hemifacial atrphy or Romberg disease, Parry Romberg syndrome and facial trophoneurosis are a rare clinical entity. It is characterized duby to facial lipid tissue, skin, bones and cartilaginosous tissue atrophy. The early diagnosis in pediatrics is sometime difficult due to being a rare event. Actual orthodontics is a medical discipline that must be treated by a multidisciplinary medical team in estomatology and pediatrics. Some of the dentofacial malocclusions and deformities have a familiar distribution that makes it necessary for ortodonthics and genetics to work together including lift and palate deformities. Pediatric cases are analyzed in this study, where hemifacial hemiatrophy are observed more frequently in female than males, and on the left facial side according to the literature. six pediatrics cases are studied where four (males) and two (females) were observed. Three males and a one female patient had a left facial side affected and two male and one female patient on the right side. All of the patients had a multidisciplinary attention both at the departments of orthodontics and genetics. [ABSTRACT FROM AUTHOR]

Introduction. The Maximum Bite Force (MBF) is a functional indicator of the masticatory system that indicates the force in kilograms force (Kf), which the dental teeth apply during chewing by means of the mandibular lifting muscles that reach high forces over short distances. There is bibliographic evidence that MBF is related to facial morphology. Objective. To identify the relationship between the Mesofacial-Brachifacial-Dolichofacial Biotypes and the MBF. Methodology. Cross-sectional, descriptive, prospective, observational study 60 young adults, both sexes, who attended the Masticatory Physiology Laboratory of the Universidad Autonoma Metropolitana Unidad Xochimilco (Mexico City) and voluntarily agreed to participate in the study. They were divided into three groups of 20 subjects each: A) mesofacial, B) brachifacial and C) dolichofacial. The facial type was measured and recorded with the Truper® digital calibrator, as well as the MBF of each young person using the T-Scan® EH-2 (Research) system, since it is an instrument that allows to evaluate the entire occlusal arch, without interfering in the interoclusal distance. Results. Mean age 22 ± 3 years and percentages of women 55% and men 45%. The Kf of the three groups: A) 46.07 Kf, for group B) 36.85 Kf, and group C) 30.98 Kf. With the ANOVA test, in the statistical program SPSS version 22. Statistically significant differences were found between A and C with a p = 0.003, between group A and B the p = 0.05 and no statistically significant difference between group B and C with a p = 0.275. Conclusion. It was determined that subjects with mesofacial and brachifacial biotype have the same statistical significance of MBF, therefore the null hypothesis was accepted, in which the brachifacial biotype is not the one with the greatest force in bite Kf. [ABSTRACT FROM AUTHOR]

Introducción. La rugoscopia durante la dentición temporal es poco estudiada. Se aplican diversas clasificaciones creadas con fines forenses. Se desconocen los patrones de su distribución y características durante la etapa de dentición temporal. Objetivo. Describir la distribución de frecuencias de las características de formas, posición, tamaño e intensidad de expresión, de las rugas palatinas de la población infantil para cada sexo. Metodología. En un estudio clínico, descriptivo, se analizó una muestra probabilística, heterodémica estratificada por sexo, de 161 arcos palatinos de la población infantil del Valle de Puebla, México, con dentición temporal completa para evaluar formas, intensidad de expresión y tamaño de las rugas palatinas, formas de arco y papila incisiva. Se aplicó en el análisis de las variables las clasificaciones de Da Silva y la de Briñón complementada por Blanco y Bollini, medidas por un solo observador (k = 0.8200 para método Da Silva y k = 0.9523 para método de Brinón complementado por Blanco y Bollini). Resultados. La forma de arco más frecuente fue la redonda, la forma y ubicación de la papila incisiva fue alargada y unida a los incisivos. El número de rugas fue mayor en el sector incisal, seguido del canino, luego por el sector molar y el posterior en los dos sexos. El tamaño largo se presentó en 46.3%, las medianas en 11% y las pequeñas en 22%. La intensidad de expresión fue de 41% en mujeres y 56% en hombres para las bien definidas, 38% (mujeres) y 22% (hombres) para las poco definidas. La distribución de las formas de la clasificación de Briñón y cols. fue diferente en cada sexo. Conclusiones. La clasificación de Da Silva es simple y genérica, utiliza formas geométricas básicas. La más completa para su descripción es la de Briñón complementada por Blanco y Bollini, que puede enriquecerse con mayores datos. [ABSTRACT FROM AUTHOR]

It has been considered important the genetic and congenital alteration studies due to consanguinity. It has been observed a high impact in specific mexican population, mainly at small towns or specific racial groups as italian, lebanese, popoloca and menonita groups, where consanguinity incidence is considered to increase. Two genetic diseases due to consanguinity are reported in this study, Albinism and Cockayne Syndrome among many other known alterations. A clinical trial is proposed in these specific diseases due to consanguinity due to recessive alterations as inborn error of metabolism, reported in México. Especially in small population towns where epidemiologic and genetic factors are found due to evolution of some specific mexican ethnic groups. [ABSTRACT FROM AUTHOR]

Dental amalgam has been usually used as the selective material in dentals restorations, alloy consisting mainly of silver, tin, copper and zinc materials which are found mixed with the Mercury. Mercury is a chemical element (metal) naturally in the environment and the people could be exposed to mercury in their diet, water, pollution and dental amalgams. People with amalgam fillings are chronically exposed to low doses of mercury. In this paper an interesting material to research is presented looking potentially effect that mercury could do on the neutrophil polymorphonuclear leukocytes. Objective. The aim of this study was to evaluate the In-Vitro Cytotoxicity from HgCI2 (mercury chloride) on LPMN. Materials and methods. 10ml of blood sample was taken from clinical healthy volunteer donors and their neutrophil polymorphonuclear leukocytes were separated and the population was adjusted and challenged with HgCI2 solution l0mM for one hour and 2 hours keeping the following concentrations: 2µg/ml, 4µg/ml, 6µg/ml, 12 ug/ml. Results. The results were obtained using the SPSS version 18.0 Statistic were that at concentrations of 12ug /ml the mercury chloride affected the viability of neutrophil polymorphonuclear leukocytes following a dose-response pattern where concentration (12µg/ml HgCI2) affected the viability of neutrophil polymorphonuclear leukocyte. Conclusions. The results showed a response the higher concentration (12µg/ml HgCI2) lower viability. [ABSTRACT FROM AUTHOR]

Objetives. Associating the amount of Strepcoccus mutans y Lactobacillus Sp before and during the use of removable orthopedic appliances in children who were about to begin orthodontic treatment. Methodology. Longitudinal, descriptive study was conducted in maxillofacial orthopedic clinic of the Facultad de Estomatología de la Benemérita Universidad Autónoma of Puebla in Mexico, during the period January to October 2011. Previous radiographic diagnosis and analysis of study models, children Maxillofacial Orthopedics initiated treatment with removable orthopedic appliances. Before placing it, every child had Strepcoccus count mutans and Lactobacillus sp. This maneuver was repeated the first, second and third month of continuous use for both orthopedic appliances Strepcoccus mutans and Lactobacillus sp. The study included 31 subjects, 19 (61.3%) women and 12 (38.7%) men, with a mean age of 8.6 ± 1.49. We compared the average of the means of S mutans with Anova test, in which it rejected the hypothesis of equality of S. mutans) to the first month of using removable orthopedic appliances (p <0.05, no finding significance in subsequent months. In relation to the Lactobacillus sp no significant results were found. We conclude that during the first month of using removable orthopedic appliances the number of colony forming units Strepcoccus mutans diminishes, and a reinforced brushed recommendations can maintain low levels of Strepcoccus mutans. [ABSTRACT FROM AUTHOR]

This article documents the findings in two male patients evaluated in the genetics department with Parry Romberg syndrome. [ABSTRACT FROM AUTHOR]

Objective. The congenital inborn errors of metabolism (IEM) were identificables diseases for Garrod in 1908. Consanguinity was an importan issue if inheritance background was observed. At the beginning, albinism, cistinuria and porfiria were estudied. Cases reported. 2 370 metabolic studies were performed, 102 clinical cases were associated to diferent inborn errors of metabolism. Some of the clinical symptoms were polymalformed muscle esqueletal and skull and dental dismorfies were presented. Those patientes Conclusions. Actually, the IEM are defined as monogenic inherited diseases or mendelians, due to a metabolic error for a protein or enzime absence. It might be incompatible with the patient life and some times if the patient lives it will modify its quality of life, with craniofacial and dental malformations, as it can be seen in patients with mucopolysaccharidosis. [ABSTRACT FROM AUTHOR]

Objetivos: General(es). Estimar la prevalencia en el país y en el estado donde existe un alto índice de desnutrición secundaria a problemas estomatológicos y nutrimentales secundarios a capacidad diferenciada. La triada de Currarino (TC) es un ejemplo de los síndromes que son causa de Capacidad Diferenciada (CD) en un ser humano, en este estudio un paciente pediátrico, se describe y aprecia la importancia de la estomatología como parte integral de la terapia pediátrica que con un manejo oportuno se obtiene un mejor pronóstico para la función y la vida del paciente. El síndrome de Currarino (SC) como se ha mencionado se transmite en forma hereditaria originalmente descrito por Currarino como una asociación malformativa de varios tejidos en un ser humano; malformación de tubo digestivo incluyendo cavidad bucal, sacro y neoplasia maligna por la formación de un teratoma presacral. En la mayoría de los casos ha sugerido un tipo de herencia autosómico dominante, pudiendo encontrar en algunas familias con este síndrome en forma incompleta con relación a sus manifestaciones clínicas reportado por Ashcraft y Holder en 1974. La alteración del hemisacro mencionado en 1998 por mutaciones en los genes HLXB9. Nagai en 1994 describió la asociación de problemas cromosómicos por una trisomía del cromosoma 13 y 20 así como aberraciones en el cromosoma 7 el cual está formado por 153 millones de pares de bases y 940 genes. Esta región curiosamente está relacionada con el desarrollo normal del sacro y presenta genes que se encargan de la formación anorectal, Lynch en 1995 reporta esta asociación con la banda 36 del brazo largo del cromosoma 7, por ello se realizó en este estudio un cariotipo en el paciente, no encontrando por este método ningún tipo de aberraciones cromosómicas, siendo el paciente normal, 46XY donde los cromosomas 7, 13 y 20 son reportados normales. Como se menciono anteriormente el paciente fue valorado por los departamentos de estomatología, medicina interna, gastroenterología y nutrición, para rehabilitación bucal por caries múltiples, constipación intestinal, incontinencia fecal, detectando posteriormente por medio de estudios una masa abdominal y un defecto en el sacro y fistula perianal. Radiografías y estudios de colon por enema demostraron defectos en la formación intestinal, megarectosigmoides con un colon descendente proximal normal. Debido a la malformación anorectal y hemisacro se inicio la búsqueda de la masa abdominal presacral, el departamento de oncología por medio de una biopsia confirma un teratoma, en comparación de un quiste dermoide o duplicación anorectal entre otros diagnósticos que se pensaron al inicio. Se observo por medio de resonancia magnética un meningocele anterior, realizando una colostomía y una cirugía sagital posterior correctiva del mismo defecto. Durante la cirugía megarectosigmoides fue observado en su región distal en comparación con la normalidad de la región proximal del colon con dilatación del sigmoides. Se realizo una sigmoidostomia reportando la biopsia del tejido, inervación normal, logrando en el posoperatorio que el paciente normalizara su transito intestinal e iniciando tratamiento nutrimental específico para el paciente. Concluyendo entonces, el paciente en este estudio se diagnostico como SC completo por la presencia de; 1.- Agenesia sacra confirmado con rayos-X de pelvis y RMI. 2.- Tumor presacral diagnosticado y confirmado como teratoma por biopsia, los estudios histológicos reportaron que la lesión estaba compuesta de una mezcla de epitelio escamoso maduro, tejido adiposo, fibras musculares lisas y elementos neurogliales donde no se encontró tejido neuroepitelial inmaduro. 3.- Malformación anorectal con la presencia de megarectosigmoides y una fistula recto-perineal que se confirmo con rayos-X y RMI se intervino quirúrgicamente con anorectoplastia posterior sagital. Cretolle en 2007 reportó que es posible el diagnóstico prenatal. Es muy importante mencionar que el estudio multidisciplinario entre los departamentos de genética, nutrición, patología, gastroenterología, cirugía pediátrica, neurocirugía, oncología y medicina interna es necesario para establecer los procedimientos necesarios y el paciente sea intervenido quirúrgicamente en forma temprana, en conjunto con el manejo oncológico oportuno para evitar el riesgo de una degeneración maligna de otros tejidos y/o metástasis. Es determinante tener en cuenta que el tratamiento estomatológico y nutrimental es básico e importante de acuerdo al daño tisular, neurológico, manejo pre/posquirúrgico y desarrollo celular maligno (cáncer), posterior a radioterapia y/o quimioterapia. Finalmente podemos concluir que el manejo integral a pacientes con CD utilizando una terapia de rehabilitación estomatológica personalizarla como parte de un equipo medico, podrán lograr un mejor pronóstico y brindar al paciente la mejor calidad de vida. [ABSTRACT FROM AUTHOR]

This article describes the characteristics of a patient with midface assymetry related to the 16 chromosome. [ABSTRACT FROM AUTHOR]