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Primary pleural lymphoma is a rare entity that has been described in association with human immunodeficiency virus (HIV) infection or pyothorax. This paper reports on a 27 year old man with no history of HIV infection or pyothorax who presented with progressive dyspnea and heaviness of chest. Chest radiography revealed complete opacification of the left hemithorax, and contrast enhanced computed tomography showed large left pleural effusion and homogeneous, extensive thickening of the parietal pleura. CT guided biopsy of thickened pleura is suggestive of non-Hodgkin’s lymphoma-T cell lymphoblastic variety. Physicians should be aware of this rare location of primary pleural lymphoma manifested by thickening of the pleura.

A 20-year-old boy presenting daily febrile episodes was suspected to have developed acute hepatic failure. Serologic tests ruled out infectious and autoimmune causes apart from drug toxicity. During clinical examinations, he was found to have generalized enlarged lymph nodes that were then taken biopsy. It was diagnosed as classical Hodgkin’s lymphoma based on histological examination of the lymph node. A bone marrow biopsy showed marrow infi ltration by Hodgkin’s lymphoma with hemophagocytosis and secondary myelofibrosis. A percutaneous liver biopsy demonstrated hepatic involvement of the same disease. After an extensive work-up, the cause of liver failure was figure out to be only attributed to the involvement of the lymphoma. Hodgkin’s lymphoma as a cause of hepatic failure is rare and young patients diagnosed as Hodgkin’s lymphoma causing hepatic failure has been reported very rarely so far.

The association between pulmonary interstitial fibrosis and the developmentof bronchogenic carcinoma in a patient with sclerodermahas been reported rarely[1]. It is hypothesized that intense epithelialproliferation that is accompanied by the fi brotic process increases theoccurrence of carcinomatous changes[2]. We report the case of a patientwho presented with 3-year history of Raynaud’s phenomenon,gradual tightening of the skin which was ignored by the patient andher family members, and a 2-week history of severe respiratory distresswith left shoulder and upper back pain followed by the developmentof paraparesis. After a series of examinations, the patient wasdiagnosed with scleroderma and simultaneously with bronchogeniccarcinoma and multiple distant metastases.