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The article discusses a research study on comparing the safety and relative efficacy of sirolimus-eluting stents (SES) and resolute zotarolimus-eluting stents (R-ZES) for patients who have de novo long coronary lesions. Subjects of the multicenter, prospective, randomized trials include 500 patients who have native coronary lesions as compared to those with long SES and R-ZES. Results showed noninferior angiographic outcomes in patients with R-ZES implantation than those with SES implantation.

The article presents a study which analyzed the optimal intravascular ultrasound (IVUS) stent area to predict angiographic in-stent restenosis (ISR) after sirolimus-eluting stent implantation for unprotected left main coronary artery (LM) disease. After intracoronary administration of 0.2 milligrams (mg) nitroglycerin, immediate poststenting IVUS imaging was performed. Bifurcation lesions with a single stent showed a lower restenosis rate similar to nonbifurcation lesions.