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2. Integrative taxonomy reveals first record of Loxosceles rufescens (Dufour, 1820) (Araneae, Sicariidae) in the Philippines

Author

Aimee Lynn Barrion-Dupo, Ireneo Lit, Jr., Camille Faith Duran, Ma. Francia Kyla Cammayo, Marnelli Alviola, Sheila Mae Mercado, Cecille Ann Osio, Orlando Eusebio, Cristian Lucañas, and Alberto Barrion

Subjects
caves, Loxosceles rufescens, loxoscelism, Biology (General), QH301-705.5
Abstract

The spider family Sicariidae Keyserling, 1880 represented by the synanthropic Mediterranean recluse spider, Loxosceles rufescens (Dufour, 1820), is reported in the Philippines for the first time, based on morphological and molecular data. The introduced spider was observed in a small cave (Kamantigue Cave) in Lobo, Batangas Province. Considering the medical importance of this spider, the proximity of its habitat to human habitation and tourist sites poses a potential public health concern.This study reports on the first record of the family Sicariidae in the Philippines and the fourth recorded occurrence of L. rufescens in Southeast Asia.

Published
2024
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3. Análisis del impacto de las controversias por factores ASG en la valuación de acciones en el mercado mexicano

Author

Martha Angélica León Alvarado, Eric Osio Cerón, and Anahi Montserrat Revilla Antonio

Subjects
inversiones, ASG, controversias, ambiental, social, gobierno corporativo, Finance, HG1-9999, Economics as a science, HB71-74
Abstract

Existe una amplia literatura sobre las motivaciones que llevan a diversos inversionistas a integrar factores ambientales, sociales y de gobierno corporativo (ASG) en sus estrategias; sin embargo, los estudios sobre esta temática se centran en los mercados desarrollados y no detallan con evidencia si estos factores, a través de las potenciales controversias que generan en su ausencia, tienen efectos significativos en la valoración de instrumentos financieros, por ej., acciones o bonos emitidos por empresas. Por esta razón, el presente estudio analiza y demuestra con evidencia estadística que las controversias asociadas a factores ASG y relacionadas con las acciones en el mercado mexicano aún no se encuentran integradas en las valuaciones correspondientes.

Published
2024
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5. SOX10-Internal Tandem Duplications and PLAG1 or HMGA2 Fusions Segregate Eccrine-Type and Apocrine-Type Cutaneous Mixed Tumors

Author

Macagno, Nicolas, Kervarrec, Thibault, Thanguturi, Soumanth, Sohier, Pierre, Pissaloux, Daniel, Mescam, Lenaïg, Jullie, Marie-Laure, Frouin, Eric, Osio, Amelie, Faisant, Monique, Le Loarer, François, Cribier, Bernard, Calonje, Eduardo, Luna, Evelyn Vanesa Erazo, Massi, Daniela, Goto, Keisuke, Nishida, Haruto, Paindavoine, Sandrine, Houlier, Aurelie, Tantot, Juliet, Benzerdjeb, Nazim, Tirode, Franck, De la Fouchardière, Arnaud, and Battistella, Maxime

Published
2024
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6. Biallelic CRELD1 variants cause a multisystem syndrome, including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections

Author

Borras, Silvia, Clark, Caroline, Dean, John, Miedzybrodzka, Zosia, Ross, Alison, Tennant, Stephen, Dabir, Tabib, Donnelly, Deirdre, Humphreys, Mervyn, Magee, Alex, McConnell, Vivienne, McKee, Shane, McNerlan, Susan, Morrison, Patrick J., Rea, Gillian, Stewart, Fiona, Cole, Trevor, Cooper, Nicola, Cooper-Charles, Lisa, Cox, Helen, Islam, Lily, Jarvis, Joanna, Keelagher, Rebecca, Lim, Derek, McMullan, Dominic, Morton, Jenny, Naik, Swati, O’Driscoll, Mary, Ong, Kai-Ren, Osio, Deborah, Ragge, Nicola, Turton, Sarah, Vogt, Julie, Williams, Denise, Bodek, Simon, Donaldson, Alan, Hills, Alison, Low, Karen, Newbury-Ecob, Ruth, Norman, Andrew M., Roberts, Eileen, Scurr, Ingrid, Smithson, Sarah, Tooley, Madeleine, Abbs, Steve, Armstrong, Ruth, Dunn, Carolyn, Holden, Simon, Park, Soo-Mi, Paterson, Joan, Raymond, Lucy, Reid, Evan, Sandford, Richard, Simonic, Ingrid, Tischkowitz, Marc, Woods, Geoff, Bradley, Lisa, Comerford, Joanne, Green, Andrew, Lynch, Sally, McQuaid, Shirley, Mullaney, Brendan, Berg, Jonathan, Goudie, David, Mavrak, Eleni, McLean, Joanne, McWilliam, Catherine, Reavey, Eleanor, Azam, Tara, Cleary, Elaine, Jackson, Andrew, Lam, Wayne, Lampe, Anne, Moore, David, Porteous, Mary, Baple, Emma, Baptista, Júlia, Brewer, Carole, Castle, Bruce, Kivuva, Emma, Owens, Martina, Rankin, Julia, Shaw-Smith, Charles, Turner, Claire, Turnpenny, Peter, Tysoe, Carolyn, Bradley, Therese, Davidson, Rosemarie, Gardiner, Carol, Joss, Shelagh, Kinning, Esther, Longman, Cheryl, McGowan, Ruth, Murday, Victoria, Pilz, Daniela, Tobias, Edward, Whiteford, Margo, Williams, Nicola, Barnicoat, Angela, Clement, Emma, Faravelli, Francesca, Hurst, Jane, Jenkins, Lucy, Jones, Wendy, Ajith Kumar, V.K., Lees, Melissa, Loughlin, Sam, Male, Alison, Morrogh, Deborah, Rosser, Elisabeth, Scott, Richard, Wilson, Louise, Beleza, Ana, Deshpande, Charu, Flinter, Frances, Holder, Muriel, Irving, Melita, Izatt, Louise, Josifova, Dragana, Mohammed, Shehla, Molenda, Aneta, Robert, Leema, Roworth, Wendy, Ruddy, Deborah, Ryten, Mina, Yau, Shu, Bennett, Christopher, Blyth, Moira, Campbell, Jennifer, Coates, Andrea, Dobbie, Angus, Hewitt, Sarah, Hobson, Emma, Jackson, Eilidh, Jewell, Rosalyn, Kraus, Alison, Prescott, Katrina, Sheridan, Eamonn, Thomson, Jenny, Bradshaw, Kirsty, Dixit, Abhijit, Eason, Jacqueline, Haines, Rebecca, Harrison, Rachel, Mutch, Stacey, Sarkar, Ajoy, Searle, Claire, Shannon, Nora, Sharif, Abid, Suri, Mohnish, Vasudevan, Pradeep, Canham, Natalie, Ellis, Ian, Greenhalgh, Lynn, Howard, Emma, Stinton, Victoria, Swale, Andrew, Weber, Astrid, Banka, Siddharth, Breen, Catherine, Briggs, Tracy, Burkitt-Wright, Emma, Chandler, Kate, Clayton-Smith, Jill, Donnai, Dian, Douzgou, Sofia, Gaunt, Lorraine, Jones, Elizabeth, Kerr, Bronwyn, Langley, Claire, Metcalfe, Kay, Smith, Audrey, Wright, Ronnie, Bourn, David, Burn, John, Fisher, Richard, Hellens, Steve, Henderson, Alex, Montgomery, Tara, Splitt, Miranda, Straub, Volker, Wright, Michael, Zwolinski, Simon, Allen, Zoe, Bernhard, Birgitta, Brady, Angela, Brooks, Claire, Busby, Louise, Clowes, Virginia, Ghali, Neeti, Holder, Susan, Ibitoye, Rita, Wakeling, Emma, Blair, Edward, Carmichael, Jenny, Cilliers, Deirdre, Clasper, Susan, Gibbons, Richard, Kini, Usha, Lester, Tracy, Nemeth, Andrea, Poulton, Joanna, Price, Sue, Shears, Debbie, Stewart, Helen, Wilkie, Andrew, Albaba, Shadi, Baker, Duncan, Balasubramanian, Meena, Johnson, Diana, Parker, Michael, Quarrell, Oliver, Stewart, Alison, Willoughby, Josh, Crosby, Charlene, Elmslie, Frances, Homfray, Tessa, Jin, Huilin, Lahiri, Nayana, Mansour, Sahar, Marks, Karen, McEntagart, Meriel, Saggar, Anand, Tatton-Brown, Kate, Butler, Rachel, Clarke, Angus, Corrin, Sian, Fry, Andrew, Kamath, Arveen, McCann, Emma, Mugalaasi, Hood, Pottinger, Caroline, Procter, Annie, Sampson, Julian, Sansbury, Francis, Varghese, Vinod, Baralle, Diana, Callaway, Alison, Cassidy, Emma J., Daniels, Stacey, Douglas, Andrew, Foulds, Nicola, Hunt, David, Kharbanda, Mira, Lachlan, Katherine, Mercer, Catherine, Side, Lucy, Temple, I. Karen, Wellesley, Diana, Ambrose, J.C., Arumugam, P., Baple, E.L., Bleda, M., Boardman-Pretty, F., Boissiere, J.M., Boustred, C.R., Caulfield, M.J., Chan, G.C., Craig, C.E.H., Daugherty, L.C., de Burca, A., Devereau, A., Elgar, G., Foulger, R.E., Fowler, T., FurióTarí, P., Hackett, J.M., Halai, D., Hamblin, A., Henderson, S., Holman, J.E., Hubbard, T.J.P., Ibáñez, K., Jackson, R., Jones, L.J., Kasperaviciute, D., Kayikci, M., Lahnstein, L., Lawson, K., Leigh, S.E.A., Leong, I.U.S., Lopez, F.J., MaleadyCrowe, F., Mason, J., McDonagh, E.M., Moutsianas, L., Mueller, M., Murugaesu, N., Need, A.C., Odhams, C.A., Patch, C., Perez-Gil, D., Polychronopoulos, D., Pullinger, J., Rahim, T., Rendon, A., Riesgo-Ferreiro, P., Rogers, T., Ryten, M., Savage, K., Sawant, K., Scott, R.H., Siddiq, A., Sieghart, A., Smedley, D., Smith, K.R., Sosinsky, A., Spooner, W., Stevens, H.E., Stuckey, A., Sultana, R., Thomas, E.R.A., Thompson, S.R., Tucci, A., Walsh, E., Watters, S.A., Welland, M.J., Williams, E., Witkowska, K., Acosta, Maria T., Adam, Margaret, Adams, David R., Agrawal, Pankaj B., Alejandro, Mercedes E., Alvey, Justin, Amendola, Laura, Andrews, Ashley, Ashley, Euan A., Azamian, Mahshid S., Bacino, Carlos A., Bademci, Guney, Baker, Eva, Balasubramanyam, Ashok, Baldridge, Dustin, Bale, Jim, Bamshad, Michael, Barbouth, Deborah, Bayrak-Toydemir, Pinar, Beck, Anita, Beggs, Alan H., Behrens, Edward, Bejerano, Gill, Bennet, Jimmy, Berg-Rood, Beverly, Bernstein, Jonathan A., Berry, Gerard T., Bican, Anna, Bivona, Stephanie, Blue, Elizabeth, Bohnsack, John, Bonnenmann, Carsten, Bonner, Devon, Botto, Lorenzo, Boyd, Brenna, Briere, Lauren C., Brokamp, Elly, Brown, Gabrielle, Burke, Elizabeth A., Burrage, Lindsay C., Butte, Manish J., Byers, Peter, Byrd, William E., Carey, John, Carrasquillo, Olveen, Peter Chang, Ta Chen, Chanprasert, Sirisak, Chao, Hsiao-Tuan, Clark, Gary D., Coakley, Terra R., Cobban, Laurel A., Cogan, Joy D., Coggins, Matthew, Cole, F. Sessions, Colley, Heather A., Cooper, Cynthia M., Craigen, William J., Crouse, Andrew B., Cunningham, Michael, D'Souza, Precilla, Dai, Hongzheng, Dasari, Surendra, Davids, Mariska, Dayal, Jyoti G., Deardorff, Matthew, Dell'Angelica, Esteban C., Dhar, Shweta U., Dipple, Katrina, Doherty, Daniel, Dorrani, Naghmeh, Douine, Emilie D., Draper, David D., Duncan, Laura, Earl, Dawn, Eckstein, David J., Emrick, Lisa T., Eng, Christine M., Esteves, Cecilia, Estwick, Tyra, Falk, Marni, Fernandez, Liliana, Ferreira, Carlos, Fieg, Elizabeth L., Findley, Laurie C., Fisher, Paul G., Fogel, Brent L., Forghani, Irman, Fresard, Laure, Gahl, William A., Glass, Ian, Godfrey, Rena A., Golden-Grant, Katie, Goldman, Alica M., Goldstein, David B., Grajewski, Alana, Groden, Catherine A., Gropman, Andrea L., Gutierrez, Irma, Hahn, Sihoun, Hamid, Rizwan, Hanchard, Neil A., Hassey, Kelly, Hayes, Nichole, High, Frances, Hing, Anne, Hisama, Fuki M., Holm, Ingrid A., Hom, Jason, Horike-Pyne, Martha, Huang, Alden, Huang, Yong, Isasi, Rosario, Jamal, Fariha, Jarvik, Gail P., Jarvik, Jeffrey, Jayadev, Suman, Johnston, Jean M., Karaviti, Lefkothea, Kelley, Emily G., Kennedy, Jennifer, Kiley, Dana, Kohane, Isaac S., Kohler, Jennefer N., Krakow, Deborah, Krasnewich, Donna M., Kravets, Elijah, Korrick, Susan, Koziura, Mary, Krier, Joel B., Lalani, Seema R., Lam, Byron, Lam, Christina, Lanpher, Brendan C., Lanza, Ian R., Lau, C. Christopher, LeBlanc, Kimberly, Lee, Brendan H., Lee, Hane, Levitt, Roy, Lewis, Richard A., Lincoln, Sharyn A., Liu, Pengfei, Liu, Xue Zhong, Longo, Nicola, Loo, Sandra K., Loscalzo, Joseph, Maas, Richard L., Macnamara, Ellen F., MacRae, Calum A., Maduro, Valerie V., Majcherska, Marta M., Mak, Bryan, Malicdan, May Christine V., Mamounas, Laura A., Manolio, Teri A., Mao, Rong, Maravilla, Kenneth, Markello, Thomas C., Marom, Ronit, Marth, Gabor, Martin, Beth A., Martin, Martin G., Martínez-Agosto, Julian A., Marwaha, Shruti, McCauley, Jacob, McCormack, Colleen E., McCray, Alexa T., McGee, Elisabeth, Mefford, Heather, Merritt, J. Lawrence, Might, Matthew, Mirzaa, Ghayda, Morava, Eva, Moretti, Paolo M., Morimoto, Marie, Mulvihill, John J., Murdock, David R., Nakano-Okuno, Mariko, Nath, Avi, Nelson, Stan F., Newman, John H., Nicholas, Sarah K., Nickerson, Deborah, Nieves-Rodriguez, Shirley, Novacic, Donna, Oglesbee, Devin, Orengo, James P., Pace, Laura, Pak, Stephen, Pallais, J. Carl, Papp, Jeanette C., Parker, Neil H., Phillips, John A., Posey, Jennifer E., Potocki, Lorraine, Pusey, Barbara N., Quinlan, Aaron, Raskind, Wendy, Raja, Archana N., Rao, Deepak A., Renteria, Genecee, Reuter, Chloe M., Rives, Lynette, Robertson, Amy K., Rodan, Lance H., Rosenfeld, Jill A., Rosenwasser, Natalie, Ruzhnikov, Maura, Sacco, Ralph, Sampson, Jacinda B., Samson, Susan L., Saporta, Mario, Scott, C. Ron, Schaechter, Judy, Schedl, Timothy, Scott, Daryl A., Sharma, Prashant, Shin, Jimann, Signer, Rebecca, Sillari, Catherine H., Silverman, Edwin K., Sinsheimer, Janet S., Sisco, Kathy, Smith, Edward C., Smith, Kevin S., Solem, Emily, Solnica-Krezel, Lilianna, Stoler, Joan M., Stong, Nicholas, Sullivan, Jennifer A., Sun, Angela, Sutton, Shirley, Sweetser, David A., Sybert, Virginia, Tabor, Holly K., Tamburro, Cecelia P., Tekin, Mustafa, Telischi, Fred, Thorson, Willa, Tifft, Cynthia J., Toro, Camilo, Tran, Alyssa A., Tucker, Brianna M., Urv, Tiina K., Vanderver, Adeline, Velinder, Matt, Viskochil, Dave, Vogel, Tiphanie P., Wahl, Colleen E., Wallace, Stephanie, Walley, Nicole M., Walsh, Chris A., Walker, Melissa, Wambach, Jennifer, Wan, Jijun, Wang, Lee-Kai, Wangler, Michael F., Ward, Patricia A., Wegner, Daniel, Wener, Mark, Wenger, Tara, Perry, Katherine Wesseling, Westerfield, Monte, Wheeler, Matthew T., Whitlock, Jordan, Wolfe, Lynne A., Woods, Jeremy D., Yamamoto, Shinya, Yang, John, Yu, Guoyun, Zastrow, Diane B., Zhao, Chunli, Zuchner, Stephan, Jeffries, Lauren, Mis, Emily K., McWalter, Kirsty, Donkervoort, Sandra, Brodsky, Nina N., Carpier, Jean-Marie, Ji, Weizhen, Ionita, Cristian, Roy, Bhaskar, Morrow, Jon S., Darbinyan, Armine, Iyer, Krishna, Aul, Ritu B., Chao, Katherine R., Cobbold, Laura, Cohen, Stacey, Custodio, Helena M., Drummond-Borg, Margaret, Finanger, Erika, Hainline, Bryan E., Helbig, Ingo, Hewson, Stacy, Hu, Ying, Jackson, Adam, Konstantino, Monica, Leach, Meganne E., McCormick, David, Nelson, Stanley, Nguyen, Joanne, Nugent, Kimberly, Ortega, Lucy, Goodkin, Howard P., Roeder, Elizabeth, Roy, Sani, Sapp, Katie, Saade, Dimah, Sisodiya, Sanjay M., Stals, Karen, Towner, Shelley, Wilson, William, Khokha, Mustafa K., Bönnemann, Carsten G., Lucas, Carrie L., and Lakhani, Saquib A.

Published
2024
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8. Diagnostic and therapeutic recommendations in adult dystonia: a joint document by the Italian Society of Neurology, the Italian Academy for the Study of Parkinson’s Disease and Movement Disorders, and the Italian Network on Botulinum Toxin

Author

Romano, Marcello, Bagnato, Sergio, Altavista, Maria Concetta, Avanzino, Laura, Belvisi, Daniele, Bologna, Matteo, Bono, Francesco, Carecchio, Miryam, Castagna, Anna, Ceravolo, Roberto, Conte, Antonella, Cosentino, Giuseppe, Eleopra, Roberto, Ercoli, Tommaso, Esposito, Marcello, Fabbrini, Giovanni, Ferrazzano, Gina, Lalli, Stefania, Mascia, Marcello Maria, Osio, Maurizio, Pellicciari, Roberta, Petrucci, Simona, Valente, Enza Maria, Valentino, Francesca, Zappia, Mario, Zibetti, Maurizio, Girlanda, Paolo, Tinazzi, Michele, Defazio, Giovanni, and Berardelli, Alfredo

Published
2022
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9. Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey

Author

Kervarrec, Thibault, Tallet, Anne, Macagno, Nicolas, de la Fouchardière, Arnaud, Pissaloux, Daniel, Tirode, Franck, Bravo, Ignacio G., Nicolas, Alain, Baulande, Sylvain, Sohier, Pierre, Balme, Brigitte, Osio, Amélie, Jullie, Marie-Laure, Moulonguet, Isabelle, Bonsang, Benjamin, Tournier, Emilie, Herfs, Michael, Frouin, Eric, Zidan, Anoud, Calonje, Eduardo, Berthon, Patricia, Touzé, Antoine, Seris, Alice, Mortier, Laurent, Jouary, Thomas, Cribier, Bernard, and Battistella, Maxime

Published
2023
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12. Addiction to tobacco smoking and vaping

Author

Andrea Hernández-Pérez, Leonor García-Gómez, Robinson Robles-Hernández, Ireri Thirión-Romero, Jennifer Osio-Echánove, Sebastián Rodríguez-Llamazares, Ruben Baler, and Rogelio Pérez-Padilla

Subjects
Nicotine addiction. Smoking. Vaping. E-Cigarette. Genetic susceptibility., Internal medicine, RC31-1245
Abstract

The tobacco epidemic has been one of the biggest public health threats, and smoking is one of the world’s largest preventable causes of premature death. An estimated 15.4% of all deaths in the world are attributable to tobacco smoking. The present review aims to describe addiction to tobacco smoking and vaping. Tobacco and vaping devices contain nicotine, a highly addictive drug, which explains why smoking is so prevalent and persistent. Electronic cigarettes are a group of novel nicotine or tobacco products that have rapidly gained popularity in recent years. Electronic cigarette devices allow for the use of other drugs, including THC, while the lax regulation may allow for the introduction of toxic compounds that can lead to acute or subacute toxicity, such as the e-cigarette- or vaping-associated lung injury that has been linked to vitamin E acetate. In addition, regular vapers and heated tobacco devices emit toxins, although at lower concentrations than burned tobacco. However, more and more side effects have been identified. No new effective treatment for nicotine addiction has been developed recently, despite its huge adverse impact on overall health and other outcomes. As for the primary line of medications, the last one started in 2006, the varenicline, demonstrating a low interest in developing new medications against smoking, an unacceptable state of affairs, given the huge impact of smoking on morbidity and mortality.

Published
2023
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15. percepção de docentes a respeito de Atividades não Presenciais realizadas durante o isolamento social causado pela pandemia da COVID-19

Author

Iury de Almeida Accordi and Andréia Ambr´´osio-Accordi

Subjects
Special aspects of education, LC8-6691, Technology
Abstract

Objetivou-se analisar a percepção de docentes sobre as atividades não presenciais (ANP), realizadas durante o distanciamento social causado pela pandemia da COVID-19, no Instituto Federal de Santa Catarina (IFSC), que optou por ANP e o Instituto Federal do Rio Grande do Sul (IFRS), que suspendeu suas atividades formais durante o período inicial da pandemia. Aplicou-se um formulário on-line e foram analisadas as respostas de 283 docentes. Apesar das decisões institucionais distintas, não se notou respostas muito diferentes dos docentes de ambas as instituições em relação à maioria das questões. A maioria dos docentes manifestou ser favorável às ANPs e buscou se capacitar para melhor enfrentar a nova situação. Os docentes buscaram formas sólidas de se capacitarem didática e pedagogicamente para a aplicação de um ensino não presencial, bem como de se comunicarem de forma efetiva com seus discentes. Conclui-se que o aprendizado com as ANPs fornecerá uma base sólida para um novo tipo de interação docente/discente, potencializando o uso de tecnologias emergentes na aplicação de atividades e estendendo a comunicação por meio das mídias a aplicativos sociais disponíveis. Palavras-chave: Tecnologias emergentes; ensino remoto; Institutos Federais.

Published
2022
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16. DETECTION OF DEGRADED ACACIA TREE SPECIES USING DEEP NEURAL NETWORKS ON UAV DRONE IMAGERY

Author

A. A. Osio, H.-Â. Lê, S. Ayugi, F. Onyango, P. Odwe, and S. Lefèvre

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract

Deep-learning-based image classification and object detection has been applied successfully to tree monitoring. However, studies of tree crowns and fallen trees, especially on flood inundated areas, remain largely unexplored. Detection of degraded tree trunks on natural environments such as water, mudflats, and natural vegetated areas is challenging due to the mixed colour image backgrounds. In this paper, Unmanned Aerial Vehicles (UAVs), or drones, with embedded RGB cameras were used to capture the fallen Acacia Xanthophloea trees from six designated plots around Lake Nakuru, Kenya. Motivated by the need to detect fallen trees around the lake, two well-established deep neural networks, i.e. Faster Region-based Convolution Neural Network (Faster R-CNN) and Retina-Net were used for fallen tree detection. A total of 7,590 annotations of three classes on 256×256 image patches were used for this study. Experimental results show the relevance of deep learning in this context, with Retina-Net model achieving 38.9% precision and 57.9% recall.

Published
2022
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18. Differential Efficacy of Weight Loss Interventions in Patients with Versus Without Diabetes.

Author

Losada-Díaz, Federico, Lizarazo-Bocanegra, Santiago, Perdomo-Lugo, Juan J., Gutiérrez-Romero, Sebastián A., Correa-Osio, Isabella, and Mendivil, Carlos O.

Subjects
WEIGHT loss, GLUCAGON-like peptide-1 agonists, PEOPLE with diabetes, BARIATRIC surgery, OBESITY
Abstract

Obesity is both a major risk factor for diabetes and a serious comorbidity of the condition. The twin epidemics of obesity and diabetes have spread globally over the past few decades. Treatment of obesity in patients with diabetes provides a host of clinical benefits that encompass virtually all body systems. Despite this, multiple lines of evidence suggest that the efficacy of most therapies for weight loss is significantly reduced among patients with diabetes. With this background, we summarize the evidence of a differential effect of lifestyle, pharmacological, and surgical treatments for obesity in patients with existing diabetes, and explore the potential mechanisms involved in this phenomenon. This information is then used to formulate strategies to improve weight loss outcomes for patients with diabetes. [ABSTRACT FROM AUTHOR]

Published
2024
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19. An Inexpensive and Quick Method for Genotyping of HLA Variants Included in the Spanish Pharmacogenomic Portfolio of National Health System.

Author

Taladriz-Sender, Irene, Hernández-Osio, Gina, Zapata-Cobo, Paula, Salvador-Martín, Sara, García-González, Xandra, Balas, Antonio, Sanjurjo-Sáez, María, and López-Fernández, Luis A.

Subjects
*BIOMARKERS, *GENETIC testing, *PHARMACOGENOMICS, *ALLELES, *POSSIBILITY
Abstract

The possibility of using the same genotyping technology (TaqMan) for all the genetic tests included in the new Spanish pharmacogenomics portfolio should enable the application of a multigenotyping platform to obtain a whole pharmacogenomics profile. However, HLA-typing is usually performed with other technologies and needs to be adapted to TaqMan assays. Our aim was to establish a set of TaqMan assays for correct typing of HLA-A*31:01, HLA-B*15:02, HLA-B*57:01, and HLA-B*58:01. Therefore, we searched for and selected SNVs described in different populations as surrogate markers for these HLA alleles, designed TaqMan assays, and tested in a set of samples with known HLA-A and HLA-B. HLA-A*31:01 was correctly typed with a combination of rs1061235 and rs17179220 (PPV 100%, 95% CI 84.6–100-%; NPV 100%, 95% CI 96.5–100.0%), HLA-B*15:02 with rs10484555 (PPV 100%, 95% CI 69.2–100.0%; NPV 100%, 95% CI 96.8–100.0%) and rs144012689 (PPV 100%, 95% CI 69.2–100.0%; NPV 100%, 95% CI 96.8–100.0%), and HLA-B*57:01 with rs2395029 (PPV 99.5%, 95% CI 72.9–99.3%; NPV 99.5%, 95% CI 98.3–100.0%). HLA-B*58:01 was typed using two allele-specific TaqMan probes mixed with a ß-Globin reference and treated as a genotyping assay (PPV 100.0%, 95% CI 81.5–100.0%; NPV 100%, 95% CI 96.8–100.0%). In conclusion, we demonstrated a clinically useful way to type HLA-A and HLA-B alleles included in the Spanish pharmacogenomics portfolio using TaqMan assays. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Adjunctive treatment and BoNT-A for post-stroke spasticity: Are we really focusing on the patient-centered goals?

Author

Alessio Baricich, Michele Bertoni, Andrea Santamato, Maurizio Osio, Giulio Gasperini, Alessandro Picelli, Franco Molteni, The Collaborative Working Group, Roberto Antonacci, Fabrizio Balestrieri, Marco Battaglia, Luciano Bissolotti, Margherita Borg, Marcello Campagnoli, Anna Castagna, Carmelo Chisari, Nicoletta Cinone, Claudio Corradini, Michela Cosma, Davide Dalla Costa, Paolo De Blasiis, Alessandra Del Felice, Giovanni Morone, Antonio Robecchi Majnardi, Francesco Sciarrini, Alessandro Specchia, and Carlo Trompetto

Subjects
stroke, spasticity, rehabilitation, botulinum toxin type A, adjunctive treatment, Neurology. Diseases of the nervous system, RC346-429
Published
2023
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21. Effective fisheries management instrumental in improving fish stock status

Author

Hilborn, Ray, Amoroso, Ricardo Oscar, Anderson, Christopher M., Baum, Julia K., Branch, Trevor A., Costello, Christopher, de Moor, Carryn L., Faraj, Abdelmalek, Hively, Daniel, Jensen, Olaf P., Kurota, Hiroyuki, Little, L. Richard, Mace, Pamela, McClanahan, Tim, Melnychuk, Michael C., Minto, Cóilín, Osio, Giacomo Chato, Parma, Ana M., Pons, Maite, Segurado, Susana, Szuwalski, Cody S., Wilson, Jono R., and Ye, Yimin

Published
2020

22. Thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) hydrogel particles improve workability loss and autogenous shrinkage in cement paste

Author

Anastasia N. Aday, Mohammad G. Matar, Jorge Osio-Norgaard, and Wil V. Srubar, III

Subjects
Superabsorbent polymers, Poly(N-isopropyl acrylamide) (PNIPAM), Static yield stress, Autogenous shrinkage, Cement industries, TP875-888
Abstract

In this work, we show that non-superabsorbent, thermo-responsive poly(N-isopropyl acrylamide) (PNIPAM) hydrogel particles (< 250 μm) can reduce autogenous shrinkage in cement paste and improve early-age stiffening that can be caused by traditional superabsorbent polymers (SAPs). Swelling measurements in DI water and cement filtrate solution suggest that SAP-induced early-age stiffening is caused by its super-absorbency in low-ionic solutions – a behavior not exhibited by non-superabsorbent PNIPAM. Addition of PNIPAM resulted in a 29% and 60% reduction in autogenous shrinkage strain at 14 days when used alone (0.3 wt% PNIPAM) and in combination with SAP (0.15% PNIPAM, 0.15% SAP), respectively, compared to a Control with no polymer addition. Furthermore, an addition of 0.3 wt.% PNIPAM exhibited a ∼29% and ∼37% decrease in static yield stress compared to a Control and 0.3 wt% SAP-modified cement pastes, respectively. Taken together, the results provide initial evidence to suggest that the use of hydrogels as internal curing agents may not necessarily require super-absorbency to reduce autogenous shrinkage. Non-superabsorbent hydrogels, like PNIPAM, may help reduce autogenous shrinkage while alleviating the effects of SAP-induced early-age stiffening.

Published
2022
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23. Modelación del crecimiento de aves Criollas Mexicanas, Rhode Island Red y Hy-Line Brown

Author

Leonardo Osio-Orihuela, Diego Zárate-Contreras, Francisco Antonio Cigarroa-Vázquez, Paulina Vazquez-Mendoza, and Fernando González-Cerón

Subjects
Curva de crecimiento, modelos no lineales, aves Criollas, Rhode Island Red, Hy-Line Brown., Agriculture
Abstract

El objetivo fue caracterizar el crecimiento de aves Criollas Mexicanas (CMX), Hy-Line Brown (HLB) y Rhode Island Red (RIR) mediante los modelos Gompertz-Laird (MNGL), Logístico (MNL), Richards (MNR) y Von Bertalanffy (MNVB). Se utilizaron 70 pollitas de cada genotipo. Cada ave fue identificada para registrar su peso de 7 a 210 d de edad. Los parámetros de los modelos se estimaron con el procedimiento NLIN (algoritmo de Marquardt) de SAS. Se calculó el coeficiente de determinación ajustado, criterio de información de Akaike y criterio de información Bayesiana, para cada caso. La tasa de crecimiento inicial (d−1) en aves CMX fue menor (0.047 15) que en aves RIR (0.071 69) y HLB (0.052 16). Con los cuatro modelos, la tasa de decaimiento en aves CMX fue menor, respecto a los otros genotipos. Asimismo, la edad al máximo crecimiento (d) en las aves CMX, RIR y HLB, varió de 49.4 a 87.9, de 60.7 a 81.6 y de 58.7 a 87.8, respectivamente. Por otro lado, el peso asintótico (g), estimado con los cuatro modelos varió de 2 068.5 a 2 644.3, de 1 902.4 a 2 250.9 y 2 096.3 a 2 464.5, en las aves CMX, RIR y HLB, respectivamente. Con el MNVB se obtuvo el mejor ajuste para los datos de las aves RIR y HLB, en contraste, el MNR fue mejor para las aves CMX, seguido del MNVB. El MNVB sería el más adecuado para el estudio simultáneo del crecimiento de aves CMX, RIR y HLB.

Published
2022
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27. OBJECT-BASED CHANGE DETECTION ON ACACIA XANTHOPHLOEA SPECIES DEGRADATION ALONG LAKE NAKURU RIPARIAN RESERVE

Author

A. Osio and S. Lefèvre

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract

Automated mapping of heterogeneous riparian landscape is of high interest to assess our planet. Still, it remains a challenging task due to the occurrence of flooded vegetation. While both optical and radar images can be exploited, the latter has the advantage of being independent acquisition conditions. However, and despite their popularity, the threshold-based approaches commonly used present some drawbacks such as not taking into account the spatial context and providing mixed pixels within class boundaries. In this study, we propose a novel methodology to avoid such issues by using an object-based image analysis approach on polarimetric radar data. We use our workflow to map the degrading Acacia x. species along lake Nakuru Riparian reserve, and obtain highly-accurate results.

Published
2021
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28. SPATIAL TEMPORAL MAPPING OF SPREAD OF WATER HYACINTH IN WINUM GULF, LAKE VICTORIA

Author

S. O. Nyawacha, V. Meta, and A. Osio

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract

Water hyacinth (Eichhornia crassipes) is an invasive hydro plant that invaded the waters of Lake Victoria and has since been spreading rapidly affecting the socio-economic livelihood of the community around the Lake. The weed's rapid spread is due to various anthropogenic activities in the surrounding environment among them being the eutrophication of the lake waters.This study aims at using remote sensing applications and presenting the results of the analysis of the water hyacinth Normalized Difference Vegetation Index (NDVI), water extent, and analysis of correlation with the water quality over time from Sentinel 2 satellite imagery in January 2017 to January of 2021. The analysis aims at understanding the vegetation growth coverage in the five years and sets the basis of monthly predictive modelling of the behavior of water hyacinth. Predictive modelling applies historical statistical data while trying to use trend analysis in predicting the future behavior of a phenomenon. This study also seeks to answer the research question of the role of suspended sediments and dissolved minerals in abating the spread of and growth of water hyacinth.

Published
2021
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29. Neutrophil gelatinase-associated lipocalin for urinary tract infection and pyelonephritis: a systematic review

Author

Shaikh, Kai, Rajakumar, Vinod, Osio, Victor A., and Shaikh, Nader

Subjects
Urinary tract infections -- Diagnosis, Pyelonephritis -- Diagnosis, Carrier proteins -- Health aspects, Pediatric research, Health
Abstract

Background The sensitivity and specificity of the leukocyte esterase test are relatively low for a screening test for urinary tract infection (UTI). More accurate tests could reduce both overtreatment and missed cases. This study aimed to determine whether neutrophil gelatinase-associated lipocalin (NGAL) can replace leukocyte esterase in the diagnosis of UTI and/or whether NGAL accurately identifies children with acute pyelonephritis. Methods Data sources-MEDLINE and EMBASE. We only considered published studies that evaluated the results of an index test (NGAL) against the results of urine culture (for UTI) or against the results of dimercaptosuccinic acid (for acute pyelonephritis) in children aged 0 to 18 years. Two authors independently applied the selection criteria to all citations and independently extracted the data. Results A total of 12 studies met our inclusion criteria. Four studies (920 children) included data on NGAL for UTI; eight studies (580 children) included data on NGAL for pyelonephritis. We did not pool accuracy values because the included studies used different cutoff values. For the diagnosis of UTI, urinary NGAL appeared to have better accuracy than the leukocyte esterase test in all included studies. For the diagnosis of pyelonephritis, neither plasma NGAL nor urinary NGAL had high sensitivity and/or specificity. The number of studies was the main limitation of this systematic review. Conclusions Urinary NGAL appears promising for the diagnosis of UTI; however, larger studies are needed to validate this marker as a replacement for leukocyte esterase. The use of NGAL for diagnosing acute pyelonephritis requires further study., Author(s): Kai Shaikh [sup.1] , Vinod Rajakumar [sup.1] , Victor A. Osio [sup.1] , Nader Shaikh [sup.1] Author Affiliations: (1) grid.21925.3d, 0000 0004 1936 9000, Children's Hospital of Pittsburgh, Division [...]

Published
2021
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30. Identifying management actions that promote sustainable fisheries

Author

Melnychuk, Michael C., Kurota, Hiroyuki, Mace, Pamela M., Pons, Maite, Minto, Cóilín, Osio, Giacomo Chato, Jensen, Olaf P., de Moor, Carryn L., Parma, Ana M., Richard Little, L., Hively, Daniel, Ashbrook, Charmane E., Baker, Nicole, Amoroso, Ricardo O., Branch, Trevor A., Anderson, Christopher M., Szuwalski, Cody S., Baum, Julia K., McClanahan, Tim R., Ye, Yimin, Ligas, Alessandro, Bensbai, Jilali, Thompson, Grant G., DeVore, John, Magnusson, Arni, Bogstad, Bjarte, Wort, Edward, Rice, Jake, and Hilborn, Ray

Published
2021
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32. Associated risks of smoking and possible benefits of cessation in Covid-19: a rapid narrative review

Author

Andrea Hernández-Pérez, Leonor García-Gómez, Sebastián Rodríguez-Llamazares, Ireri Thirión-Romero, Jennifer Osio-Echánove, and Rogelio Pérez-Padilla

Subjects
smoking, coronavirus, covid-19, sars-cov-2, review, Public aspects of medicine, RA1-1270
Abstract

Objective. To describe the possible risks associated to smoking in the spread and complications of Covid-19, em­phasizing in the benefits of quitting smoking. Materials and methods. The narrative review methodology and the established process for Cochrane rapid reviews were used. Results. The scientific evidence related to smoking and Covid-19 remains limited. However, there is an already documented trend in cross-sectional, clinical studies and meta-analyses on the increased risk of adverse outcomes with Covid-19 associated with tobacco use. Conclusions. It is necessary to issue a warning that persons who smoke would have greater risks in the Covid-19 pandemic, which add to the many already known risks of tobacco use. Thus, quitting smoking becomes a relevant preventive measure to better confront SARS-CoV-2.

Published
2021
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35. Plasma cell–directed therapies in monoclonal gammopathy–associated scleromyxedema

Author

Mahévas, Thibault, Arnulf, Bertrand, Bouaziz, Jean-David, Livideanu, Cristina Bulai, Osio, Amélie, Servy, Amandine, Cribier, Bernard, Sassolas, Bruno, Jachiet, Marie, Michel, Laurence, Aucouturier, Pierre, Lipsker, Dan, Frances, Camille, Sbidian, Emilie, Rybojad, Michel, Descamps, Vincent, D'Incan, Michel, Humbert, Philippe, Beylot-Barry, Marie, Passeron, Thierry, de Moreuil, Claire, Taha, Ruba Y., Hermine, Olivier, Dupuy, Alain, Barbarot, Sébastien, Debarbieux, Sébastien, Carpentier, Olivier, Brault, Fanny, Schmutz, Jean-Luc, Thomas-Beaulieu, Domitille, Modiano, Philippe, Zarnitsky, Charles, Lifermann, François, Baubion, Emilie, Limal, Nicolas, Le Bras, Fabien, Le Moigne, Marie, Tauber, Marie, Talbot, Alexis, Prud'homme, Romain, Peltier, Sandy, De Masson, Adèle, Battistella, Maxime, Bagot, Martine, Mékinian, Arsène, and Fain, Olivier

Published
2020
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38. Genomic profiling of a skin adnexal carcinomas cohort using a comprehensive high-throughput sequencing approach.

Author

Louveau, Baptiste, Nakouri, Ines, Jouenne, Fanélie, Baroudjian, Barouyr, Sadoux, Aurélie, Meda, Laetitia Da, Osio, Amélie, Reinhart, Fanny, Robert, Julien, Herms, Florian, Cribier, Bernard, Mortier, Laurent, Jouary, Thomas, Seguin, Nicole Basset, Lebbé, Céleste, Mourah, Samia, and Battistella, Maxime

Subjects
BASAL cell carcinoma, TUMOR suppressor genes, SWEAT glands, SQUAMOUS cell carcinoma, MITOGEN-activated protein kinases
Abstract

This article discusses the genomic profiling of a cohort of skin adnexal carcinomas (SACs), which are rare and challenging to diagnose due to their low incidence and morphological convergence. The study included 77 patients with SACs and used high-throughput sequencing to identify oncogenic molecular alterations. The results revealed the complexity of SACs, with various gene alterations identified in different types of SACs. The study also found that MAPK and Shh pathway alterations were common in sweat gland and hair follicle carcinomas, respectively. The findings provide insights into the oncogenic processes and potential therapeutic options for SACs. [Extracted from the article]

Published
2024
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39. SPATIAL PROCESSING OF SENTINEL IMAGERY FOR MONITORING OF ACACIA FOREST DEGRADATION IN LAKE NAKURU RIPARIAN RESERVE

Author

A. Osio, M. T. Pham, and S. Lefèvre

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract

Tree degradation in National Parks poses a serious risk to the birds and animals and to a larger extent the general ecosystem. The essence of Forest degradation mapping is to detect the extent of damage on the trees over time, hence providing stakeholders with a basis for forest rehabilitation and intervention. The study proposes a workflow for detection and classification of degrading acacia vegetation along Lake Nakuru riparian reserve. Inspired by previous research on the use of Dual Polarized Sentinel 1 Ground Range Detected (GRD) data for vegetation detection, a set of six Sentinel 1 GRD and Sentinel 2 MSI of corresponding dates (2018–2019) were used. Our study confirms the existing correlation between vegetation indices derived from optical sensors and the backscatter indices from S1 SAR image of the same land cover classes. Factors that were used in validating the results include some comparisons between pixelwise and object-based classification, with a focus on the underlying segmentation and classification algorithms, the polarimetric attributes (VV+VH intensity bands) and the reflectance bands (NIR, SWIR & GREEN), the Haralick features (GLCM) vs. some geometric attributes (area & moment of inertia). Classification carried out on the temporal datasets considering geometric attributes and the Random Forest classifier yielded the highest Overall Accuracy (OA) with 94.25 %, and a Kappa coefficient of 0.90.

Published
2020
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40. Recomendaciones para la provisión de atención paliativa a personas con COVID-19

Author

Jorge A. Ramos-Guerrero, Ramiro López-Elizalde, Leticia Asencio-Huertas, Carlos Enríquez-López, Judith García de Alba-Verduzco, Oscar Flores-Munguía, Luis Hernández-Flores, Alberto León-Alatorre, Miguel Nakamura-López, Iris Narváez-Sarmiento, Juan Reyes-Torres, Patricia Ornelas-Tavares, Livier Ortiz-Coronado, Mónica Osio-Saldaña, Nayely Salazar-Trujillo, Alejandro Quiroz-Hernández, Dalia Vásquez-Vásquez, and Bernardo Villa-Cornejo

Subjects
Public aspects of medicine, RA1-1270, Internal medicine, RC31-1245
Published
2021
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41. Comorbidities and polypharmacy among HIV-positive patients aged 50 years and over: a case–control study

Author

José Antonio Mata-Marín, Moisés Hermilo Martínez-Osio, Carla I. Arroyo-Anduiza, María de los Ángeles Berrospe-Silva, Alberto Chaparro-Sánchez, Itzel Cruz-Grajales, Javier Enrique Cruz-Herrera, Luis Antonio Uribe-Noguez, Jesus E. Gaytán-Martínez, and Medardo Jerónimo-Morales

Subjects
Comorbidity, HIV, Polypharmacy, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Objective This study was to determine and compare the prevalences of polypharmacy and comorbidities in patients aged 50 years or older with those patients younger than 50 years in a Mexican population. Results One hundred and twenty-five patients were enrolled, 60 (48%) were aged 50 years or older. The median CD4+ cell counts were 509 cells/μL (interquartile range [IQR]: 324–730) for the older patients and 384 cells/μL (IQR: 262–562) (P = 0.021) for the younger patients. Viral suppression were significantly higher in the older group: 80% vs. 63% (P = 0.037). The number of comorbidities was significantly higher in the older group, with a median of 2 (IQR: 2–3) vs. 1 (IQR: 0–1) (P ≤ 0.001). After adjustment of the logistic regression model in the older group, the following comorbidities differed between the age groups: systemic arterial hypertension (odds ratio [OR]: 15.75; 95% confidence interval [CI] 3.49–71.05; P =

Published
2019
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42. The discovery BPD (D-BPD) program: study protocol of a prospective translational multicenter collaborative study to investigate determinants of chronic lung disease in very low birth weight infants

Author

Gaston Ofman, Mauricio T. Caballero, Damian Alvarez Paggi, Jacqui Marzec, Florencia Nowogrodzki, Hye-Youn Cho, Mariana Sorgetti, Guillermo Colantonio, Alejandra Bianchi, Luis M. Prudent, Nestor Vain, Gonzalo Mariani, Jorge Digregorio, Elba Lopez Turconi, Cristina Osio, Fernanda Galletti, Mariangeles Quiros, Andrea Brum, Santiago Lopez Garcia, Silvia Garcia, Douglas Bell, Marcus H. Jones, Trent E. Tipple, Steven R. Kleeberger, and Fernando P. Polack

Subjects
Pediatrics, RJ1-570
Abstract

Abstract Background Premature birth is a growing and serious public health problem affecting more than one of every ten infants worldwide. Bronchopulmonary dysplasia (BPD) is the most common neonatal morbidity associated with prematurity and infants with BPD suffer from increased incidence of respiratory infections, asthma, other forms of chronic lung illness, and death (Day and Ryan, Pediatr Res 81: 210–213, 2017; Isayama et la., JAMA Pediatr 171:271–279, 2017). BPD is now understood as a longitudinal disease process influenced by the intrauterine environment during gestation and modulated by gene-environment interactions throughout the neonatal and early childhood periods. Despite of this concept, there remains a paucity of multidisciplinary team-based approaches dedicated to the comprehensive study of this complex disease. Methods The Discovery BPD (D-BPD) Program involves a cohort of infants

Published
2019
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50. Pensamiento computacional. Alfabetización digital sin computadoras

Author

Umberto Roncoroni Osio and Jaime Bailón Maxi

Subjects
Computación, creatividad, educación, identidad cultural, software, tecnocentrismo, Communication. Mass media, P87-96
Abstract

El pensamiento computacional es un conjunto de conocimientos en las áreas STEM introducido en los programas educativos para preparar a los estudiantes en la comprensión y el uso de los medios y las herramientas digitales. Sin embargo, no se ha tomado en cuenta que los medios digitales influyen no solo en el desarrollo del conocimiento, sino también en la economía, la cultura, la comunicación y las relaciones sociales. El objetivo de este artículo es revisar y corregir algunas limitaciones del paradigma del pensamiento computacional. Queremos demostrar, con la ayuda de la literatura científica y del trabajo de campo, que el pensamiento computacional debería incluir las humanidades, y rescatar las prácticas educativas analógicas y las tradiciones culturales locales. Para esto se estudiarán tres aspectos: a) la crítica a los fundamentos neopositivistas del tecnocentrismo; b) la naturaleza del medio digital, con la puesta en relieve del software y de la creatividad digital, y c) las metodologías y prácticas educativas, entre las que se proponen la máquina de Touring y las shape grammars. Se concluye con todo esto que, para fortalecer el pensamiento computacional, las maquinarias informáticas no son imprescindibles y hasta podrían ser contraproducentes para el aprendizaje y la creatividad.

Published
2020
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