1. Proceedings of the Sleep and Epilepsy Workshop: Section 1 Decreasing Seizures: Improving Sleep and Seizures, Themes for Future Research
- Author
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Rama Maganti, Frank Kalume, Bruce J. Gluckman, Erik K. St. Louis, Judy S. Liu, Milena Pavlova, Gordon F. Buchanan, Jay Pathmanathan, Mark Quigg, Louis J. Ptáček, Mélanie Boly, and Carl W. Bazil
- Subjects
circadian rhythm ,medicine.medical_specialty ,Seizure frequency ,SUDEP ,business.industry ,Seizure reduction ,Proceedings of the Sleep and Epilepsy Workshop ,medicine.disease ,Sleep in non-human animals ,Clinical trial ,03 medical and health sciences ,Epilepsy ,0302 clinical medicine ,Physical medicine and rehabilitation ,Multidisciplinary approach ,Basic research ,epilepsy ,Medicine ,030212 general & internal medicine ,Neurology (clinical) ,Circadian rhythm ,sleep ,business ,030217 neurology & neurosurgery ,seizures - Abstract
Epileptic seizures, sleep, and circadian timing share bilateral interactions, but concerted work to characterize these interactions and to leverage them to the advantage of patients with epilepsy remains in beginning stages. To further the field, a multidisciplinary group of sleep physicians, epileptologists, circadian timing experts, and others met to outline the state of the art, gaps of knowledge, and suggest ways forward in clinical, translational, and basic research. A multidisciplinary panel of experts discussed these interactions, centered on whether improvements in sleep or circadian rhythms improve decrease seizure frequency. In addition, education about sleep was lacking in among patients, their families, and physicians, and that focus on education was an extremely important “low hanging fruit” to harvest. Improvements in monitoring technology, experimental designs sensitive to the rigor required to dissect sleep versus circadian influences, and clinical trials in seizure reduction with sleep improvements were appropriate.
- Published
- 2021