1. [Becker's nevus associated with epidermal nevus: another example of twin spotting?].
- Author
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Rodríguez-Díaz E, Alvarez-Cuesta CC, Blanco S, Galache C, and Hidalgo Y
- Subjects
- Adolescent, Female, Hamartoma embryology, Head and Neck Neoplasms embryology, Humans, Loss of Heterozygosity, Nevus, Pigmented embryology, Shoulder, Skin Diseases embryology, Skin Neoplasms embryology, Hamartoma genetics, Head and Neck Neoplasms genetics, Mosaicism, Nevus, Pigmented genetics, Skin Diseases genetics, Skin Neoplasms genetics
- Abstract
Linear epidermal nevi are believed to be caused by an autosomal dominant lethal mutation that can only be expressed by mosaicism. Becker's nevus can be explained by paradominant inheritance which is only manifested clinically by an acquired loss of heterozygosity. We present the case of a 16-year-old female with an epidermal nevus located on the left side of the neck, and also a Becker's nevus located on the ipsilateral shoulder. It is interesting to speculate that this supposed double mosaicism could be another example of "twin spotting" or non-allelic didymosis, although the possibility that this is a chance association cannot be ruled out, as the lesions are not closely associated.
- Published
- 2006
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