Search

Your search keyword '"Dominant negative"' showing total 111 results

Search Constraints

Start Over You searched for: Descriptor "Dominant negative" Remove constraint Descriptor: "Dominant negative" Topic humans Remove constraint Topic: humans
111 results on '"Dominant negative"'

Search Results

1. Heterozygous nonsense variants in the ferritin heavy-chain gene FTH1 cause a neuroferritinopathy

2. A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies, and failure to thrive

Catalog

Books, media, physical & digital resources

3. Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A

4. Targeting ATF5 in Cancer

5. Clinical and structural insights into potential dominant negative triggers of proximal urea cycle disorders

6. p53 tetramerization: at the center of the dominant-negative effect of mutant p53

7. Diverse Molecular Mechanisms Underlying Pathogenic Protein Mutations: Beyond the Loss-of-Function Paradigm

8. A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies, and failure to thrive

9. A natural variant in ANP32B impairs influenza virus replication in human cells

10. Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling

11. Allogeneic hematopoietic stem cell transplant outcomes for patients with dominant negative IKZF1/IKAROS mutations

12. Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance

13. Author Correction: Long-QT founder variant T309I-Kv7.1 with dominant negative pattern may predispose delayed afterdepolarizations under β-adrenergic stimulation

14. Evidence for a dominant-negative mechanism in HARS1-mediated peripheral neuropathy

15. Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

16. Identification and analysis of dominant negative mutants of RIP1 DD that disrupt RIPoptosome core formation

17. Contrasting Phenotypes in Resistance to Thyroid Hormone Alpha Correlate with Divergent Properties of Thyroid Hormone Receptor α1 Mutant Proteins

18. Voluntary exercise improves cognitive deficits in female dominant-negative DISC1 transgenic mouse model of neuropsychiatric disorders

19. Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

20. Toward normalising abortion: Findings from a qualitative secondary analysis study

21. Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53

22. Anti-FIRs (PUF60) auto-antibodies are detected in the sera of early-stage colon cancer patients

23. 7p22.1 microdeletions involving ACTB associated with developmental delay, short stature, and microcephaly

24. The dominant-negative interplay between p53, p63 and p73: A family affair

25. A novel hypoxia-induced miR-147a regulates cell proliferation through a positive feedback loop of stabilizing HIF-1α

26. Protein kinase C fusion proteins are paradoxically loss of function in cancer

27. A case of Coffin–Siris syndrome with severe congenital heart disease and a novel SMARCA4 variant

28. De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder

29. The V protein of human parainfluenza virus type 2 promotes RhoA-induced filamentous actin formation

30. A Novel Mutation in NKX2-1 Shows Dominant-Negative Effects Only in the Presence of PAX8

31. Mutations in the BAF-complex subunit DPF2 associated with Coffin-Siris syndrome

32. Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities

33. CD81 large extracellular loop-containing fusion proteins with a dominant negative effect on HCV cell spread and replication

34. Targeting ATF5 in Cancer

35. Analysis ofRUNX1rearrangements: insights into leukaemogenesis mechanisms

36. Augmentation of Antipsychotics with Electroconvulsive Therapy in Treatment-Resistant Schizophrenia Patients with Dominant Negative Symptoms: A Pilot Study of Effectiveness

37. Analysis of Mutation Effects on PIDDosome Core Complex

38. Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes

39. The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer

40. Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance

41. Truncated variants of pig somatostatin receptor subtype 5 (sst5) act as dominant-negative modulators for sst2-mediated signaling

42. Attenuated CagA Oncoprotein in Helicobacter pylori from Amerindians in Peruvian Amazon

43. AES/GRG5: More than just a dominant-negative TLE/GRG family member

44. Functional analysis of melanocortin-4-receptor mutants identified in severely obese subjects living in Southern Italy

45. Photocontrol of Coiled-Coil Proteins in Living Cells

46. Dominant negative factors in health and disease

47. Flatiron Mice and Ferroportin Disease

48. Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles

49. Whole-Exome Sequencing in Nine Monozygotic Discordant Twins

50. Insights into the molecular mechanisms of action of bioportides: a strategy to target protein-protein interactions