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Your search keyword '"Fang-Xin Zhang"' showing total 6 results
Start Over Author "Fang-Xin Zhang" Topic internal medicine
6 results on '"Fang-Xin Zhang"'

1. Type I enteropathy-associated T-cell lymphoma in the colon of a 29-year-old patient and a brief literature review

Author

Jiu-Cong Zhang, Xiu-Feng Wang, Yong Wang, and Fang-Xin Zhang

Subjects
medicine.medical_specialty, Pathology, Abdominal pain, Malabsorption, Case Report, Disease, Gastroenterology, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Pharmacology (medical), ulcer, colon, business.industry, medicine.disease, enteropathy-associated T-cell lymphoma, Lymphoma, Diarrhea, liver metastasis, Oncology, 030220 oncology & carcinogenesis, Enteropathy-associated T-cell lymphoma, 030211 gastroenterology & hepatology, Differential diagnosis, medicine.symptom, business
Abstract

Enteropathy-associated T-cell lymphoma (EATL) is a rare gastrointestinal non-Hodgkin's lymphoma, originating from intraepithelial T-lymphocyte, which is specifically associated with celiac disease. EATL most commonly presents in the sixth and seventh decades of life. We report a unique case of type I EATL in the colon with liver metastasis, which was presented with nonspecific radiological findings and at a very young age (29 years old) compared with previously published data. We suggest that EATL should be regarded as part of differential diagnosis in any patient presenting with abdominal pain, diarrhea, weight loss, and malabsorption because delay in treatment can result in an irreversible clinical outcome.

Published
2016

2. Expression of breast cancer resistance protein in peripheral T cell subsets from HIV‑1‑infected patients with antiretroviral therapy

Author

Jiu‑Cong Zhang, Fang Xie, Zhi‑Yun Deng, Li Sun, Fang‑Xin Zhang, and Yong Wang

Subjects
Oncology, Adult, CD4-Positive T-Lymphocytes, Male, Cancer Research, medicine.medical_specialty, T cell, HIV Infections, Drug resistance, Biology, CD8-Positive T-Lymphocytes, medicine.disease_cause, Biochemistry, Peripheral blood mononuclear cell, Internal medicine, Antiretroviral Therapy, Highly Active, Genetics, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Humans, RNA, Messenger, Molecular Biology, Oncogene, Cancer, Middle Aged, Viral Load, medicine.disease, Molecular medicine, Neoplasm Proteins, medicine.anatomical_structure, Immunology, HIV-1, Leukocytes, Mononuclear, Molecular Medicine, Reverse Transcriptase Inhibitors, ATP-Binding Cassette Transporters, Female, Carcinogenesis, CD8
Abstract

The aim of the present study was to investigate the expression of breast cancer resistance protein (BCRP) in peripheral T cell subsets of human immunodeficiency virus 1 (HIV‑1)‑infected patients, and to analyze the association between the levels of BCRP expression and disease progression in HIV‑1 infection. Peripheral blood mononuclear cells (PBMCs) were obtained from HIV‑1‑infected patients (n=118), including 92 patients with antiretroviral therapy (ART) and 26 patients without a history of ART. Control samples from 30 healthy donors were also analyzed. The expression levels of BCRP in T cells were evaluated by flow cytometry. A high inter‑individual variability was observed in CD4+ and CD8+ T cells in the HIV‑1‑infected patients and healthy donors; however, the analyzed expression levels of BCRP were significantly higher in the HIV‑1‑infected group with ART than those in the group with no history of ART (P

Published
2013

3. Use of serum circulating CCNB2 in cancer surveillance

Author

Min Liu, Min-Li Mo, Run-Gui Niu, Junpu Xu, Da-Qiang Sun, Mei-Lin Xu, Fang-Xin Zhang, Ya-Wei Hua, Zhao Chen, Hui-Yan Ma, Qing Sheng, Hai-Meng Zhou, Li Hailong, Xun Zhang, Jie Li, and Hui-Jing Zuo

Subjects
Male, Transcriptional Activation, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Genital Neoplasms, Female, Clinical Biochemistry, Digestive System Neoplasms, Gastroenterology, Pathology and Forensic Medicine, law.invention, Metastasis, 03 medical and health sciences, 0302 clinical medicine, law, Neoplasms, Internal medicine, Biomarkers, Tumor, medicine, Humans, Cyclin B2, RNA, Messenger, Polymerase chain reaction, Aged, Cyclin, Messenger RNA, Lung, Receiver operating characteristic, business.industry, Area under the curve, Cancer, Middle Aged, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Urinary Bladder Neoplasms, Oncology, Case-Control Studies, 030220 oncology & carcinogenesis, Female, business
Abstract

Cyclin B2 (CCNB2), a member of the cyclin protein family, has been found to be up-regulated in human cancers. To evaluate the potential use of circulating CCNB2 in serum in cancer surveillance, we examined relative expression levels of serum circulating CCNB2 mRNA in 103 cancer patients, 19 normal controls, and 40 benign disease patients using real-time quantitative reverse transcriptase polymerase chain reaction. We found that the relative expression level of circulating CCNB2 mRNA in cancer patients was significantly higher (p

Published
2010

5. Severe hepatitis and intestinal mucosal barrier

Author

Fang-Xin Zhang, Zhi-Yun Deng, and Ti-Dong Shan

Subjects
medicine.medical_specialty, business.industry, Internal medicine, medicine, Intestinal mucosal barrier, business, Gastroenterology, Hepatitis a virus
Published
2010

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