1. Photoluminescent carbon dots synthesized by microwave treatment for selective image of cancer cells
- Author
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Hong Xu, Chunyan Su, Shouying Li, Zhenyu Li, Xudong Yang, Yexuan Han, Yang Chen, Xinyuan Bu, Quan Lin, Yingnan Jiang, and Yang Xue
- Subjects
Diagnostic Imaging ,Luminescence ,Materials science ,Photoluminescence ,Biocompatibility ,Photochemistry ,chemistry.chemical_element ,Quantum yield ,Biocompatible Materials ,Nanotechnology ,Microscopy, Atomic Force ,Cell Line ,Biomaterials ,Folic Acid ,Colloid and Surface Chemistry ,Microscopy, Electron, Transmission ,X-Ray Diffraction ,Neoplasms ,Quantum Dots ,Humans ,Urea ,Microwaves ,Fluorescent Dyes ,Water ,Fluorescence ,Carbon ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,chemistry ,Folate receptor ,Cancer cell ,Solvents ,Microwave ,HeLa Cells ,Nuclear chemistry - Abstract
In this work, a simple, low-cost and one-step microwave approach has been demonstrated for the synthesis of water-soluble carbon dots (C-dots). The average size of the resulting C-dots is about 4 nm. From the photoluminescence (PL) measurements, the C-dots exhibit excellent biocompatibility and intense PL with the high quantum yield (QY) at Ca. 25%. Significantly, the C-dots have excellent biocompatibility and the capacity to specifically target the cells overexpressing the folate receptor (FR). These exciting results indicate the as-prepared C-dots are promising biocompatible probe for cancer diagnosis and treatment.
- Published
- 2015