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A recent study conducted by researchers at Northwest University in China explores the impact of geopolitical risks on firms' internationalization performance. The study focuses on Chinese manufacturing listed firms from 2008 to 2019 and finds that geopolitical risks have a significantly negative effect on firms' internationalization performance. These risks primarily reduce legitimacy and investment freedom, and their impact varies depending on factors such as product diversification, technological diversification, and regional diversification. The study suggests that geopolitical risks have a more significant inhibitory effect on firms' internationalization in developing countries along the Belt and Road and joint ventures investing. This research contributes to a better understanding of the relationship between geopolitical risks and firms' internationalization. [Extracted from the article]

A recent study conducted by researchers at Jimei University in China examined the impact of COVID-19 on cruise ship emissions in China. The study found that cruise activities in China's Emission Control Area (ECA) significantly reduced emissions, with sulfur oxide (SOx) emissions decreasing by 59.11% compared to 2019. The researchers suggest that cruise operators can further mitigate the negative effects on the marine environment by improving fuel efficiency, decreasing vessel speed, improving routing and scheduling, and enhancing fleet management. The study provides valuable insights for the global shipping industry and the cruise tourism sector. [Extracted from the article]

A systematic review conducted by researchers at the Acupuncture Department of Ningbo Hospital of Traditional Chinese Medicine in China evaluated the effectiveness of transcutaneous electrical acupoint stimulation (TEAS) in preventing postoperative urinary retention (POUR). The review included 14 studies with 2865 participants and found that TEAS reduced the incidence of POUR and decreased post-void residual urine volume. The preventive effect of TEAS was observed in patients undergoing anorectal, gynecologic, orthopedic, and biliary surgery, but not urinary surgery. However, the researchers noted the need for further high-quality studies to confirm these findings. [Extracted from the article]

A study conducted by researchers at Guizhou Medical University in China explored the relationship between peripheral immune cell counts and mouth ulcers (MUs) using a two-sample Mendelian randomization approach. The study found that higher counts of leukocytes, lymphocytes, and CD4+ cells were associated with a decreased risk of MUs, while higher counts of CD8+ cells were associated with an increased risk. These findings suggest that immune factors play a significant role in the development of MUs. The study was published in the journal Heliyon and more information can be obtained from the affiliated hospital or the publisher, Elsevier. [Extracted from the article]

A recent study conducted by researchers at the Shengli Clinical Medical College of Fujian Medical University in China has identified a novel variant in the ATAD3A gene that is associated with Harel-Yoon syndrome (HAYOS). HAYOS is a rare genetic disorder characterized by various clinical features, including seizures, laryngeal stridor, hypotonia, feeding difficulties, corneal opacity, and respiratory failure. The study expands the understanding of the mutation spectrum associated with ATAD3A and provides a comprehensive description of the clinical characteristics observed during the neonatal phase of HAYOS. This research may contribute to improved clinical recognition and management of ATAD3A-associated HAYOS. [Extracted from the article]

A new study conducted in China examined the angiographic anatomy of the superior sagittal sinus (SSS) and its adjacent structures using computed tomography angiography (CTA) in Han Chinese participants. The study found that the inferior sagittal sinus (ISS) may become occluded and the Rolandic bridging vein may become thinner with age. However, other parameters of the SSS and its adjacent structures were not affected by aging. The study also provided normal CTA parameters for the SSS and its adjacent structures in Han Chinese individuals. [Extracted from the article]

A patent application by inventors from Qingdao University of Science and Technology in China describes a process and device for continuous flow side-chain alkylation to produce ibuprofen. The current production process for ibuprofen involves complex batch reactions that result in unstable product quality and high energy consumption. The new method proposed in the patent application aims to address these issues by using continuous chemical synthesis, which allows for precise control of reaction times and reduces impurities. The process involves various steps, including preheating, mixing, reaction, cooling, and extraction, resulting in a high yield and purity of the ibuprofen raw material. The inventors claim that this continuous synthesis method is cost-effective and efficient. [Extracted from the article]

A recent study conducted at the Affiliated Drum Tower Hospital of Nanjing University Medical School in China explored the role of a molecule called DDX3X in the progression of nonalcoholic steatohepatitis (NASH), a liver disease characterized by metabolic stress and inflammation. The researchers found that DDX3X has different effects in different cell types. In macrophages, it inhibits inflammation and promotes anti-inflammatory responses, while in hepatocytes, it contributes to the development of steatohepatitis. The study suggests that understanding these cell-specific differences could help in the development of targeted treatments for NASH. [Extracted from the article]

This document provides information about a Phase II clinical trial in China for patients with advanced Stage IV colorectal cancer. The trial aims to evaluate the effectiveness and safety of combining Cadonilimab, Fruquintinib, and stereotactic body radiation therapy (SBRT) as a third-line and posterior line treatment for patients with oligometastatic colorectal cancer. The trial is currently recruiting participants and will assess various outcomes such as progression-free survival, objective response rate, disease control rate, overall survival, and quality of life. The trial has specific eligibility criteria and is being conducted by the Huazhong University of Science and Technology. The document does not provide information about data sharing or the involvement of a data monitoring committee. [Extracted from the article]

A study conducted at the Second Affiliated Hospital of Harbin Medical University in China explored the relationship between coronary artery calcification (CAC) and plaque stability. The researchers analyzed data from 419 patients with acute coronary syndrome who underwent optical coherence tomography (OCT). They found that vulnerable features were more frequently observed in culprit plaques with spotty calcification, while the presence of macrocalcification did not significantly increase plaque vulnerability. The study also revealed that calcification tended to be larger in culprit plaques compared to non-culprit plaques. This research provides valuable insights into the morphological significance of CAC and its impact on plaque stability. [Extracted from the article]

A research study conducted by Hangzhou Normal University in China examined the perceptions of Chinese undergraduate students regarding the use of videoconferencing for learning English as a foreign language (EFL) during the COVID-19 pandemic. The study found that students' satisfaction and participation intention were significantly influenced by their perceived ease of use and perceived usefulness of videoconferencing. Additionally, students' computer self-efficacy positively affected their perceived ease of use, perceived usefulness, and participation intention. The research contributes to the existing literature on the acceptance of videoconferencing in EFL learning and provides insights for developing effective videoconferencing teaching strategies. [Extracted from the article]

A recent study conducted by researchers at Anhui Medical University in China explored the effects of plasma-activated solution (PAS) on rats. PAS is an indirect method of cold atmospheric plasma (CAP) treatment that has shown promise in treating various skin diseases. The study found that multiple subcutaneous injections of PAS did not have significant toxic side effects on local skin tissues or vital organs in rats. The results suggest that PAS could be a potential treatment for skin diseases in the future. [Extracted from the article]

A recent study conducted at the Shanghai Public Health Clinical Center in China focused on adult-onset Mendelian Susceptibility to Mycobacterial Disease (MSMD). The study examined the case of a 27-year-old man who developed the disease at 18 years old and found that he had a TYK2 mutation. The researchers also reviewed previous cases of adult-onset MSMD and identified 12 cases in total. The study found that the average age of disease onset was 29.4 years and the average delay in diagnosis was 2.5 years. Common symptoms included lymphadenopathy, weight loss, bone/joint pain, fever, and gastrointestinal symptoms. The study concluded that adult-onset MSMD can be difficult to recognize, leading to delayed diagnosis, but antibiotics and IFN-g can be effective treatments. The researchers recommend considering MSMD in adult patients with recurrent and refractory mycobacterial infections, particularly in lymph nodes, bone/joints, and skin. [Extracted from the article]

A recent study conducted by researchers at Jiangsu University in China explores the implementation of occupational health and safety management in the supply chain by core enterprises. The study utilizes the grounded theory method and semi-structured interviews to analyze different management modes within the supply chain. The research identifies three modes of occupational health and safety management employed by core enterprises: defensive mode, passive mode, and strategic mode. The study concludes that understanding the characteristics of these modes can guide core enterprises in transitioning from defensive to strategic management modes. This research provides valuable insights for improving working conditions in the supply chain. [Extracted from the article]

Researchers from the Affiliated Hospital of Qingdao University in China have conducted a review on the role of CD47 in non-neoplastic diseases. CD47 is a membrane receptor that plays a crucial role in various cellular processes. The review focuses on the involvement of CD47 in neurological disorders, atherosclerosis, and autoimmune diseases, and discusses the potential of targeting CD47 as part of immune modulatory strategies. The research also addresses the challenges and potential remedies associated with CD47-SIRPa-based immunotherapies. This information is available in the journal article "The role of CD47 in non-neoplastic diseases" published in Heliyon. [Extracted from the article]

The US Patent and Trademark Office has published a patent application from inventors at Qingdao University of Science and Technology in China. The application describes a method and device for purifying ibuprofen intermediate raw materials through a multi-stage distillation process. The method achieves high product recovery rates and purity levels, with the purity of isobutyl benzene reaching 99.99 wt % and the recovery rate reaching 99.9 wt %. The inventors have also developed a device specifically designed for the separation and purification of isobutyl benzene, suitable for industrial and continuous production. [Extracted from the article]

A recent study conducted by researchers at Weifang Medical University in China examined the efficacy and safety of ciprofol (HSK3486) for procedural sedation and anesthesia induction in surgical patients. The study analyzed 15 randomized controlled trials involving 2,441 patients and found that ciprofol showed similar advantages to propofol in terms of induction success rate and induction time, but did not increase the incidence of adverse events. Ciprofol was also found to significantly reduce injection pain and may have reduced the incidence of hypotension and respiratory depression. The researchers concluded that ciprofol is an effective alternative to intravenous anesthetic agents. [Extracted from the article]

A recent study conducted by researchers at Xiamen University in China explored the effects of low-intensity exercise training on cardiovascular health. The study focused on cardiac resident macrophages (cMacs), which play a crucial role in maintaining heart function. The researchers found that low-intensity exercise training resulted in an increase in the ejection fraction, a measure of systolic function, and a redistribution of cMac subsets. These findings suggest that exercise may have benefits for cardiovascular fitness by enhancing heart function and altering the distribution of cMacs. Further research is needed to fully understand the mechanisms behind these effects. [Extracted from the article]

A recent meta-analysis conducted by researchers at the Second Affiliated Hospital of Fujian Medical University in China explored the effects of treatment with stem cell-derived extracellular vesicles (sEVs) in preclinical rodent models of intrauterine adhesion (IUA). IUA is a condition that often arises from complications of intrauterine surgery or infection and is difficult to treat. The meta-analysis included seven studies and found that treatment with sEVs led to a reduction in fibrosis area, an increase in endometrial gland number, and an improvement in endometrial thickness. These findings provide valuable insights for future preclinical research on IUA treatment. [Extracted from the article]

A research study conducted by Shandong Technology and Business University in China has proposed a new method for accurately segmenting skin lesions in medical images. The study addresses the limitations of existing Convolutional Neural Networks (CNNs) by introducing an attention mechanism called EA-Net, which improves the preservation of relevant features and local details. The researchers conducted extensive experiments on skin lesion images and found that EA-Net outperformed the U-Net model, achieving higher scores in terms of Dice score, Intersection over Union (IoU), and Average Symmetric Surface Distance (ASSD). This research contributes to the field of skin lesion image segmentation and demonstrates the potential of attention mechanisms in improving neural network performance. [Extracted from the article]

A new study conducted by the Chinese Academy of Sciences focuses on the early stage of the Early Cretaceous Jehol Biota in China, specifically the Huajiying Formation. The study reports the discovery of a more complete pterosaur specimen, assigned to the Ctenochasmatidae group, and establishes a new taxon based on unique characteristics. The study also investigates the relative thickness of bone walls among pterosaurs, finding that most non-pterodactyloids, archaeopterodactyloids, and dsungaripterids have smaller R/t ratios than other groups. The research concludes that the thin-walled humerus and radius of dsungaripterids evolved to meet the needs of flight, rather than for frequent take-off and landing as previously believed. [Extracted from the article]

A case report from researchers at the Second Hospital of Jilin University in China highlights the relationship between arsenic exposure and the development of keratosis and cutaneous carcinoma. The report focuses on a 60-year-old patient with psoriasis who had been taking arsenic-containing traditional Chinese medicine for 15 years. The patient presented with multiple cutaneous carcinomas, including basal cell carcinoma, Bowen disease, and squamous cell carcinomas. This case is rare and underscores the potential risks associated with long-term use of arsenic-containing traditional Chinese medicine. [Extracted from the article]

A patent has been issued for a purification method and device for the continuous distillation and separation of ibuprofen intermediate raw material. The inventors aim to improve the production process for ibuprofen intermediates in China, as the current process is outdated and results in low-quality products. The method described in the patent achieves a high recovery rate and product purity, with simple steps and high purification efficiency. The patent was filed by Qingdao University Science and Technology in China. [Extracted from the article]

A study conducted in southern China aimed to investigate the association between body mass index (BMI) and the PXDNL gene with acute primary angle closure (APAC) and primary angle-closure glaucoma (PACG). The study included 4,700 participants and found that BMI and body weight were significantly associated with both APAC and PACG. Additionally, the study identified a genetic variant in the PXDNL gene that was associated with a higher risk of APAC. The researchers concluded that lower BMI may be linked to a higher risk of APAC and that PXDNL could be a new associated gene for this condition. [Extracted from the article]

A recent report from researchers at the First Affiliated Hospital of Xi'an Jiaotong University in China discusses the applications of cold atmospheric plasma (CAP) in immune-mediated inflammatory diseases. CAP has shown positive outcomes in surface disinfection, wound repair, tissue regeneration, and solid tumor therapy. The research highlights that CAP can impact immune response and inflammatory conditions by down-regulating the expression of certain cytokines and managing immune-mediated inflammatory disorders through oxidative stress. The study concludes by suggesting directions for future investigation. For more information, the full research article can be accessed through the provided link. [Extracted from the article]

A study conducted at the First Affiliated Hospital of Guangzhou Medical University in China aimed to differentiate between lung allograft rejection and infection in lung transplant recipients (LTRs) using plasma donor-derived cell-free DNA (dd-cfDNA) and metagenomic next-generation sequencing (mNGS) for pathogen detection. The study found that elevated levels of plasma dd-cfDNA, in combination with negative mNGS results, strongly indicated lung allograft rejection. The research concluded that plasma dd-cfDNA, along with BALF pathogen detection by mNGS, showed satisfactory accuracy in distinguishing between lung allograft rejection and infectious complications in LTRs. [Extracted from the article]

This document provides administrative information about a clinical trial conducted in China for the treatment of relapsed or refractory large B-cell lymphoma. The trial is being conducted by Shanghai Ming Ju Biotechnology Co., Ltd. and involves adult patients who have already been treated with Relmacabtagene Autoleucel. The trial is expected to be completed by December 2024. The document also includes contact information for the primary investigator and collaborating hospitals. [Extracted from the article]

A study conducted at the Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine in China explored the role of the mTORC1 pathway in adipose fibrosis, a major factor in adipose dysfunction during obesity. The researchers used ob/ob mice and 3T3-L1 preadipocytes to investigate the effects of inhibiting the mTORC1 pathway on fibrosis-related gene expression and protein levels. The study found that inhibiting the mTORC1 pathway reduced fibrosis-related gene expression and ameliorated adipose fibrosis in both hypoxia- and TGF-b-induced fibrotic preadipocytes. This research provides insights into the molecular mechanisms underlying adipose fibrosis and its potential treatment. [Extracted from the article]

A study conducted by researchers at Xi'an Jiaotong University in China aimed to discuss the appropriate treatment of esophageal fistula following anterior surgery for cervical spine fracture. The study analyzed the clinical data of patients with cervical spine fracture treated at their research center from 2000 to 2019. Out of 3,578 patients, 10 cases (0.28%) of esophageal fistula were identified, with 60% being early-onset and all caused by intraoperative electric knife injury. The study concluded that esophageal fistula occurrence is associated with surgical procedures, esophageal injury, and implant compression, and recommended treatments include various approaches such as muscle flap packing, lavage and drainage, and removal of internal fixation if necessary. [Extracted from the article]

A recent study conducted by Gannan Medical College in China investigated the clinical effect of high-flow humidified oxygen therapy (HFNC) on patients after cardiac surgery. The study compared the outcomes of patients who received HFNC via nasal cavity with those who received oxygen inhalation by face mask. The results showed that HFNC was associated with higher arterial partial pressure of oxygen (PaO2), lower sputum viscosity, reduced incidence of second intubation, and shorter intensive care unit (ICU) stay time compared to conventional mask oxygen inhalation. The study suggests that HFNC is a beneficial respiratory support strategy for patients after cardiac surgery and can contribute to their recovery. [Extracted from the article]

The following topics are under this section: Shanghai neurologists test brain implant to tackle drug addiction Bio-imaging breakthrough developed by China-Australia collaboration Gene-editing researchers reduce cancer risk Beijing Genomics Institute to invest in construction of the National Genome Science Data Centre DNA data storage becomes a top emerging technology Researchers find new gene linked to deafness Scientists discover highest energy cosmic gamma rays in Tibet China tightens rules on genetic research after rogue scientist He Jiankui's designer baby scandal First remote 5G breast cancer surgery a success Vaccine shortage hits many parts of China First China-Belgium Science and Technology Exchange Symposium held in Brussels Latest news on biotechnology and research from China [ABSTRACT FROM AUTHOR]

This paper reviews ethics dumping incidents in China's biomedical research field and analyzes the underlying causes to answer why China is often susceptible to ethics dumping. Keywords: Asia; China; Drugs and Therapies; Pharmacology; Science And Technology; Technology EN Asia China Drugs and Therapies Pharmacology Science And Technology Technology 1118 1118 1 09/11/23 20230915 NES 230915 2023 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New study results on pharmacology have been published. [Extracted from the article]

Keywords: 3-Hydroxybutyric Acid; Agricultural; Agriculture; Animal Science; Asia; Bioengineering; Biomedical Engineering; Biomedicine; Biotechnology; Carboxylic Acids; China; Gram-Positive Asporogenous Rods; Gram-Positive Bacteria; Gram-Positive Rods; Health and Medicine; Hydroxybutyrates; Lactobacillaceae; Lactobacillales; Lactobacillus; Organic Chemicals; Science And Technology; Science China Press; Tissue Engineering EN 3-Hydroxybutyric Acid Agricultural Agriculture Animal Science Asia Bioengineering Biomedical Engineering Biomedicine Biotechnology Carboxylic Acids China Gram-Positive Asporogenous Rods Gram-Positive Bacteria Gram-Positive Rods Health and Medicine Hydroxybutyrates Lactobacillaceae Lactobacillales Lactobacillus Organic Chemicals Science And Technology Science China Press Tissue Engineering 2023 MAR 9 (NewsRx) -- By a News Reporter-Staff News Editor at Veterinary Week -- Maintainance of sulfomucin is a key end point in the treatment of diarrhea and inflammatory bowel disease (IBD). L. johnsonii-biofilm alleviate colitis by regulating fucose residues to promote goblet cell differentiation and subsequent sulfomucin maturation. [Extracted from the article]