1. Outcomes of surgical intervention for anomalous aortic origin of a coronary artery: A large contemporary prospective cohort study.
- Author
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Mery CM, De León LE, Molossi S, Sexson-Tejtel SK, Agrawal H, Krishnamurthy R, Masand P, Qureshi AM, McKenzie ED, and Fraser CD Jr
- Subjects
- Adolescent, Child, Computed Tomography Angiography methods, Female, Humans, Magnetic Resonance Imaging, Cine methods, Male, Myocardial Perfusion Imaging methods, Outcome and Process Assessment, Health Care, Replantation methods, United States, Aorta abnormalities, Aorta diagnostic imaging, Aorta surgery, Chest Pain diagnosis, Chest Pain etiology, Chest Pain physiopathology, Coronary Vessel Anomalies diagnosis, Coronary Vessel Anomalies physiopathology, Coronary Vessel Anomalies surgery, Coronary Vessels diagnostic imaging, Coronary Vessels surgery, Postoperative Complications diagnosis, Postoperative Complications physiopathology, Vascular Surgical Procedures adverse effects, Vascular Surgical Procedures methods
- Abstract
Objective: The purpose of this study was to prospectively analyze the outcomes of patients with anomalous aortic origin of a coronary artery undergoing surgical intervention according to a standardized management algorithm., Methods: All patients aged 2 to 18 years undergoing surgical intervention for anomalous aortic origin of a coronary artery between December 2012 and April 2017 were prospectively included. Patients underwent stress nuclear perfusion imaging, stress cardiac magnetic resonance imaging, and retrospectively electrocardiogram-gated computed tomography angiography preoperatively. Patients were cleared for exercise at 3 months postoperatively if asymptomatic and repeat stress nuclear perfusion imaging, stress cardiac magnetic resonance imaging, and computed tomography angiography showed normal results., Results: A total of 44 patients, with a median age of 14 years (8-18 years), underwent surgical intervention: 9 (20%) for the anomalous left coronary artery and 35 (80%) for the anomalous right coronary artery. Surgical procedures included unroofing in 35 patients (80%), translocation in 7 patients (16%), ostioplasty in 1 patient (2%), and side-side-anastomosis in 1 patient (2%). One patient who presented with aborted sudden cardiac death from an anomalous left coronary and underwent unroofing presented 1 year later with a recurrent episode and was found to have an unrecognized myocardial bridge and persistent compression of the coronary requiring reintervention. At last follow-up, 40 patients (91%) are asymptomatic and 4 patients have nonspecific chest pain; 42 patients (95%) have returned to full activity, and 2 patients are awaiting clearance., Conclusions: Surgical treatment for anomalous aortic origin of a coronary artery is safe and should aim to associate the coronary ostium with the correct sinus, away from the intercoronary pillar. After surgery, the majority of patients are cleared for exercise and remain asymptomatic. Longer follow-up is needed to assess the true efficacy of surgery in the prevention of sudden cardiac death., (Copyright © 2017 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
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