Search

Tidal salt marsh soils can be a dynamic source of greenhouse gases such as carbon dioxide (CO 2), methane (CH 4), and nitrous oxide (N 2 O), as well as sulfur-based trace gases such as carbon disulfide (CS 2) and dimethylsulfide (DMS) which play roles in global climate and carbon–sulfur biogeochemistry. Due to the difficulty in measuring trace gases in coastal ecosystems (e.g., flooding, salinity), our current understanding is based on snapshot instantaneous measurements (e.g., performed during daytime low tide) which complicates our ability to assess the role of these ecosystems for natural climate solutions. We performed continuous, automated measurements of soil trace gas fluxes throughout the growing season to obtain high-temporal frequency data and to provide insights into magnitudes and temporal variability across rapidly changing conditions such as tidal cycles. We found that soil CO 2 fluxes did not show a consistent diel pattern, CH 4 , N 2 O, and CS 2 fluxes were highly variable with frequent pulse emissions (> 2500 %, > 10 000 %, and > 4500 % change, respectively), and DMS fluxes only occurred midday with changes > 185 000 %. When we compared continuous measurements with discrete temporal measurements (during daytime, at low tide), discrete measurements of soil CO 2 fluxes were comparable with those from continuous measurements but misrepresent the temporal variability and magnitudes of CH 4 , N 2 O, DMS, and CS 2. Discrepancies between the continuous and discrete measurement data result in differences for calculating the sustained global warming potential (SGWP), mainly by an overestimation of CH 4 fluxes when using discrete measurements. The high temporal variability of trace gas fluxes complicates the accurate calculation of budgets for use in blue carbon accounting and earth system models. [ABSTRACT FROM AUTHOR]

Molybdenum disulfide (MoS 2) is considered a low-cost material that may replace platinum-based electrocatalysts towards hydrogen evolution reaction (HER). However, the catalytic activity of MoS 2 is limited by the low conductivity and lack of active sites. Here, a biomass carbon dots-molybdenum disulfide (BCDs-MoS 2) composite was synthesized as a HER catalyst by a simple hydrothermal method. The BCDs-MoS 2 catalyst displayed excellent electrocatalytic performance for HER with lower onset overpotential (115 mV), smaller Tafel slope (56.57 mV dec−1) as well as high cycling stability, which superior to those of homemade MoS 2 , commercial MoS 2 , and most of the reported MoS 2 -based catalysts. According to the characterization results of morphology, surface properties, and valence states of elements, the outstanding catalytic activity of BCDs-MoS 2 is ascribed to its loose structure with a large specific surface area along with abundant edges and defects, and the increase in the amount of S 2 2− and S2− which possess higher activity due to the addition of the BCDs. This study can afford a new strategy to design high performance HER catalysts. • A BCDs-MoS 2 composite catalyst was prepared via a hydrothermal method. • BCDs-MoS 2 exhibits superior electrocatalytic activity for HER in acid solution. • The high catalytic activity is ascribed to its loose structure caused by the BCDs. • Electron interactions between BCD and MoS 2 also contribute to the catalytic activity. • BCDs-MoS 2 possesses favorable long-term stability besides high catalytic activity. [ABSTRACT FROM AUTHOR]

The (thio)urea and benzothiazole (BT) derivatives have been shown to have a broad spectrum of biological activities. These groups, when bonded, result in the 2-(thio)ureabenzothizoles (TBT and UBT), which could favor the physicochemical and biological properties. UBTs and TBTs are compounds of great importance in medicinal chemistry. For instance, Frentizole is a UBT derivative used for the treatment of rheumatoid arthritis and systemic lupus erythematosus. The UBTs Bentaluron and Bethabenthiazuron are commercial fungicides used as wood preservatives and herbicides in winter corn crops. On these bases, we prepared this bibliography review, which covers chemical aspects of UBTs and TBTs as potential therapeutic agents as well as their studies on the mechanisms of a variety of pharmacological activities. This work covers synthetic methodologies from 1935 to nowadays, highlighting the most recent approaches to afford UBTs and TBTs with a variety of substituents as illustrated in 42 schemes and 13 figures and concluded with 187 references. In addition, this interesting review is designed on chemical reactions of 2-aminobenzothiazoles (2ABTs) with (thio)phosgenes, iso(thio)cyanates, 1,1′-(thio)carbonyldiimidazoles [(T)CDI]s, (thio)carbamoyl chlorides, and carbon disulfide. This topic will provide information of utility for medicinal chemists dedicated to the design and synthesis of this class of compounds to be tested with respect to their biological activities and be proposed as new pharmacophores. [ABSTRACT FROM AUTHOR]

A novel dimerization of 3-chlorooxindoles promoted by potassium ethylxanthate to access isoindigo derivatives is described. The reactions proceeded readily at room temperature in short reaction times. A mechanistic study revealed that the 3-chlorooxindole is initially converted into O -ethyl S -(2-oxo-2,3-dihydro-1 H -indol-3-yl) dithiocarbonate, which subsequently undergoes dimerization with elimination of carbon disulfide. In almost all cases, analytically pure isoindigos were isolated in moderate to good yields without a requirement for chromatographic purification. [ABSTRACT FROM AUTHOR]

Vine leaves, which are produced fresh, brined or fermented from the leaves of Vitis Vinifera in Türkiye are an important food. Sulfur is used as a pesticide and sulfur compounds can be used as additives during the growing and processing of the vine leaves. These sulfur sources cause positive results on carbon disulfide (CS2) measurements by GC-MS. Therefore, the main objective of the present study was to investigate the effects of residues of sulfur or sulfur compounds on dithiocarbamate analysis methods based on CS2 measurement. For this, vine leaves were produced by controlled agricultural production and processed as brine under controlled conditions. The sulfur dioxide (SO2) and dithiocarbamate analysis were carried out on the vine leave obtained by applying sulfur spraying in agricultural treatments and brined vine leaves produced by adding sodium metabisulfite (SM), and control samples of each stage. SO2 was not detected in any of the samples in this study. SO2 residues did not occur in the vine leaves as a result of the sulfur spraying application and therefore did not have a false positive effect on dithiocarbamate analysis. However, approximately 0.15 mg kg−1 false positive dithiocarbamate was detected, which is thought to originate from natural sulfur in the vine leaves. The effect of SM, which was used in low concentration in the production of brined vine leaves, on dithiocarbamate results was limited. Even if SM was not used, the total false positive dithiocarbamate result in the brined vine leaves production process was approximately determined as 0.20 mg kg−1. This study showed that the dithiocarbamates analysis method based on CS2 measurement may lead to false positive results in brined vine leaves since sulfur compounds are found naturally in vine leaves. [ABSTRACT FROM AUTHOR]

The synthesis of alicyclic 2-methylenethiazolo[2,3- b ]quinazo-l-inones is performed via base-promoted cascade reactions, starting from either alicyclic β-amino propargylamides using carbon disulfide, or from alicyclic ethyl 2-isothiocyanatocarboxylates by addition of propargylamine. In both cases the cascade reaction proceeds by way of a favoured 5 - exo -dig process during the second ring closure, as confirmed by full NMR spectroscopic assignments. Moreover, a high-yielding retro--Diels–Alder (RDA) reaction is performed on the norbornene derivatives leading to 2-methylene-2 H -thiazolo[3,2- a ]pyrimidin-5(3 H)-ones. The obtained compounds exert modest antiproliferative activities against a panel of human gynaecological cancer cell lines. [ABSTRACT FROM AUTHOR]

In this work, prereactive complexes, reaction products, and conformational preferences derived from the photochemical reaction between CS2 and ClF were analyzed following the codeposition of the reactants trapped in argon matrices at cryogenic temperatures. After codeposition of CS2 and ClF diluted in Ar, the formation of van der Waals complexes is observed. When the mixture is subsequently irradiated by means of broad-band UV-visible light (225 ≤ λ ≤ 800 nm), fluorothiocarbonylsulfenyl chloride (FC(S)SCl) and chlorothiocarbonylsulfenyl fluoride (ClC(S)SF) are produced. These species exist as two stable planar anti- and syn-conformers (anti- and syn- of the C=S double bond with respect to the S–Cl or S–F single bond, respectively). For both novel molecules, anti-FC(S)SCl and anti-ClC(S)SF are the lowest-energy computed rotamers. As expected due to the photochemical activity of these species, additional reaction products due to alternative or subsequent photochannels are formed during this process. [ABSTRACT FROM AUTHOR]

A novel type of mercaptobenzothiazole disulfide (MBTS) modified carbon paste electrode (CPE-MBTS) was developed in the present study. DFT calculations identified an enhanced electrophilic character, and conductance of the modified electrode's interface, through bismuth coadsorption with the studied metal cations. Also, the strong binding energy of Cu2+ on the MBTS adsorption sites facilitates its selective and quantitative detection. Experimentally, the electrode was able to detect Cd, Cu and Pb, showing greater affinity for Cu, so the electrochemical study was focused on optimizing the selectivity and sensitivity of CPE-MBTS towards this metal. The detection of copper was done by square wave anodic stripping voltammetry (SWASV), yielding a LOD and LOQ of 0.34 ppm and 1.02 ppm, respectively, with good repeatability. The analysis of real samples showed the reliability of this electrode for the detection of Cu2+ in different types of waters. [ABSTRACT FROM AUTHOR]

A novel method for the synthesis of substituted thioureas is being reported in this communication making use of easily available, less toxic and cost effective chemicals at normal conditions of temperature and pressure. The reaction of various aliphatic and aromatic amines with CS2, methyl iodide using Triton-B as phase transfer catalyst led to the formation of substituted thioureas. This new method involved one flask reaction at room temperature and pressure conditions with high yield and easier separation of compound from the reaction mixture. [ABSTRACT FROM AUTHOR]

Piperazine-based dithiocarbamates serve as important scaffolds for numerous pharmacologically active drugs. The current study investigates the design and synthesis of a series of dithiocarbamates with a piperazine unit as well as their biological activities. Under ultrasound conditions, the corresponding piperazine-1-carbodithioates 5a–5j were synthesized from monosubstituted piperazine 2 and N-phenylacetamides 4a–4j in the presence of sodium acetate and carbon disulfide in methanol. The structures of the newly synthesized piperazines were confirmed, and their anti-lung carcinoma effects were evaluated. A cytotoxic assay was performed to assess the hemolytic and thrombolytic potential of the synthesized piperazines 5a–5j. The types of substituents on the aryl ring were found to affect the anticancer activity of piperazines 5a–5j. Piperazines containing 2-chlorophenyl (5b; cell viability = 25.11 ± 2.49) and 2,4-dimethylphenyl (5i; cell viability = 25.31 ± 3.62) moieties demonstrated the most potent antiproliferative activity. On the other hand, piperazines containing 3,4-dichlorophenyl (5d; 0.1%) and 3,4-dimethylphenyl (5j; 0.1%) rings demonstrated the least cytotoxicity. The piperazine with the 2,5-dimethoxyphenyl moiety (5h; 60.2%) showed the best thrombolytic effect. To determine the mode of binding, in silico modeling of the most potent piperazine (i.e., 5b) was performed, and the results were in accordance with those of antiproliferation. It exhibits a similar binding affinity to PQ10 and an efficient conformational alignment with the lipophilic site of PDE10A conserved for PQ10A. [ABSTRACT FROM AUTHOR]

We constructed a coating with controllable microstructure on the substrate by static breath figure (BF) method. In the atmosphere of water, when the fluorine‐containing 1H,1H,2H,2H‐perfluorooctyl polyacrylate‐block‐polystyrene copolymer (PTFOA‐b‐PS (4 h)) synthesized via atom transfer radical polymerization for 4 h was dissolved in carbon disulfide (CS2) and then coated on the silicon wafer, the concentrated pore size and uniform micro‐pore structure was successfully constructed on the surface. However, the hydrophobicity of the resulting microporous coating was not so good. An interesting result is that when the copolymer solution of PTFOA‐b‐PS (2 h) in tetrahydrofuran (THF) was used under the MeOH/H2O atmosphere (the methanol content was 60% or 80%), the microsphere coating can be produced on the substrate surface to obtain the excellent hydrophobicity. The water contact angles (WCAs) were 148.8 ± 1.8° and 150.3 ± 1.8°, respectively. Energy dispersive X‐ray spectrometer (EDS) results showed that the fluorine element was enriched in the outerfield of the microsphere coating. The low surface energy of fluorine combined with the rough and complex structure of the microspheres can effectively improve the hydrophobicity of the coating. [ABSTRACT FROM AUTHOR]

An efficient one-pot, solvent-free synthesis of pyrazolone-1,3-dithiolan hybrid derivatives from the reaction of 2-pyrazoline-5-ones, carbon disulfide, and α-chloroacetaldehyde in the presence of triethylamine is reported. Two possible stereoisomers (E and Z) can be formed in this reaction. The structures of the produced 5-pyrazolone-1,3-dithiolan derivatives are determined based on their IR, 1H NMR, 13C NMR, and mass spectroscopic data. The 4-hydroxy-1,3-dithiolan moieties in hybrid products 2a and 2 g are readily converted to the related dehydrated products 3a and 3 g, respectively. [ABSTRACT FROM AUTHOR]

A liquid-gated super-slippery copper mesh was prepared by the following steps: (a) anodic oxidation to fabricate a rough structure by in-situ growth of Cu(OH)2 nano-needles on the surface of copper mesh; (b) modification with fluoroalkylsilane to form a superhydrophobic surface; and (c) dropping ethylene glycol onto the surface of the superhydrophobic copper mesh. The contact angle to oil and water, morphology, and composition of the superhydrophobic copper mesh surface were analyzed with contact angle goniometer, scanning electron microscope, and X-ray diffractometer, respectively. The oil contact angle of the super-slippery copper mesh filled with ethylene glycol was also measured. The results showed that the superhydrophobic copper mesh featured a contact angle of 150° to water and 0° to carbon disulfide. The separation efficiency of carbon disulfide, petroleum ether, or n-hexane from water was higher than 90% when using the superhydrophobic copper mesh initially and still maintained 85% after reusing it for 50 cycles. The contact angle of the superslippery copper mesh filled with ethylene glycol to the said three kinds of organic liquids was larger than 140°, and the separation efficiency of them from carbon disulfide was 95% above when using the super-slippery copper mesh. [ABSTRACT FROM AUTHOR]

Aryl halides containing electron‐withdrawing substituent(s) at ortho and para position undergoes aromatic nucleophilic substitution reaction with sulfur nucleophile present in dithiocarbamate anions at room temperature. In the present study, several cyclic and acyclic secondary amines reacted in situ with carbon disulfide to form dithiocarbamate anions, which then react with different haloarenes resulting in the formation of aryldithiocarbamates. A series of aryldithiocarbamates are obtained in high yields by this procedure. [ABSTRACT FROM AUTHOR]

Soluble sulfur (S8) and insoluble sulfur (IS) have different application fields, and molecular dynamics simulation can reveal their differences in solubility in solvents. It is found that in the simulated carbon disulfide (CS2) solvent, soluble sulfur in the form of clusters mainly promotes the dissolution of clusters through van der Waals interaction between solvent molecules (CS2) and S8, and the solubility gradually increases with the increase in temperature. However, the strong interaction between polymer chains of insoluble sulfur in the form of polymer hinders the diffusion of IS into CS2 solvent, which is not conducive to high-temperature dissolution. The simulated solubility parameter shows that the solubility parameter of soluble sulfur is closer to that of the solvent, which is consistent with the above explanation that soluble sulfur is easy to dissolve. [ABSTRACT FROM AUTHOR]

Copyright of Clean Coal Technology is the property of Clean Coal Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Nowadays heterocyclic compounds containing pyrimidine scaffold attract the interest of many organic chemists due to their strong biological activity, so herein we present the synthesis of new polycyclic compounds starting from 4-chloro-9-phenyl-N-(p-tolyl)pyrimido[5',4':4,5]thieno[3,2-d][1,2,3]triazin-7-amine (1) which allowed to react with hydrazine hydrate to give hydrazinyl triazine compound (2) which subjected to some ring closure reactions using various reagents represented in triethyl orthoformate, acetyl acetone, and carbon disulfide to give compounds (3–5), respectively. Also, when the hydrazinyl compound was allowed to react with acetophenone, ethoxymethylene ethylcyano acetate, and diethyl malonate gave the derivatives (9–11), respectively. The structures of all newly synthesized compounds were confirmed using spectral analysis techniques as well as elemental analysis. Besides, four new compounds were screened for their antimicrobial activity using different strains of bacteria and fungi, and compound 5 displayed the best antimicrobial activity among all the tested compounds. [ABSTRACT FROM AUTHOR]

A polyethylene glycol (PEG)-promoted methodology has been utilized for synthesis of piperazine-based dithiocarbamates. One-pot reaction of N-methylpiperazine and N-Boc-piperazine with various substituted arylmethyl bromides or 2-bromo-1-phenylethanone and carbon disulfide using PEG as solvent afforded the target S-alkyl piperazine-1-carbodithioates in high yields (80–90%). The synthesized compounds were charac-terized by 1H and 13C NMR and FT-IR spectroscopy. Furthermore, cytotoxic potential of these piperazine derivatives was evaluated via hemolysis and thrombolysis. The synthesized compounds displayed hemolytic potential in the range from 0.1±0.004 to 9.63±0.249% and thrombolytic activity in the range from 48.17±0.016 to 63.56±0.124%. [ABSTRACT FROM AUTHOR]

Odor released from the sewage sludge composting process often has a negative impact on the sewage sludge treatment facility and becomes a hindrance to promoting compost technology. This study investigated the effect of adding KNO3 on the emissions of volatile sulfur compounds, such as hydrogen sulfide (H2S), dimethyl sulfide (DMS), and carbon disulfide (CS2), during sewage sludge composting and on the physicochemical properties of compost products, such as arylsulfatase activity, available sulfur, total sulfur, moisture content, and germination index. The results showed that the addition of KNO3 could inhibit the emissions of volatile sulfur compounds during composting. KNO3 can also increase the heating rate and peak temperature of the compost pile and reduce the available sulfur loss. The addition of 4% and 8% KNO3 had the best effect on H2S emissions, and it reduced the emissions of H2S during composting by 19.5% and 20.0%, respectively. The addition of 4% KNO3 had the best effect on DMS and CS2 emissions, and it reduced the emissions of DMS and CS2 by 75.8% and 63.0%, respectively. Furthermore, adding 4% KNO3 had the best effect from the perspective of improving the germination index of the compost. [ABSTRACT FROM AUTHOR]

[Display omitted] Constructing hybrid photocatalysts with advanced structures and controllable compositions is a promising way to improve CO 2 photoreduction performance. In this work, SnS 2 nanosheets are grown on ZnS polyhedron cages to fabricate hierarchical ZnS@SnS 2 double-shelled heterostructured cages. This design integrates ZnS cages and SnS 2 nanosheets into a stable heterostructured hybrid catalyst with a hierarchical double-shelled cage-like architecture, possessing abundant active sites, quick charge separation/migration, and high CO 2 adsorption capacity. Benefiting from these advantages, the optimized hierarchical ZnS@SnS 2 heterostructured cages exhibit significant gas-phase CO 2 photoreduction activity with a CO generation rate of 95.38 μmol g−1h−1 and 72.4% CO selectivity, which are greatly improved in comparison with those of pure ZnS cages and nanosheet-assembled SnS 2 particles. Furthermore, charge carrier separation efficiency and visible light harvesting ability are further improved by constructing a ZnS@SnS 2 /CdS type-I/type-II complex heterostructured system through surface decoration of CdS quantum dots. The optimized ZnS@SnS 2 /CdS hybrid exhibits a CO generation rate of 155.57 μmol g−1h−1 and an excellent selectivity of 80.4%. This work is conducive to the design and manufacture of advanced hybrids for solar energy utilization and photocatalytic reactions. [ABSTRACT FROM AUTHOR]

The reaction of ethyl 3-oxobutanoate, carbon disulfide, and chloroacetone in the presence of K2CO3 afforded a novel bis(2-thienyl)disulfide derivative (4). The structure of the synthesized compound was confirmed by spectral and X-ray analyses. Hirshfeld quantitative analysis of molecular packing showed that the H···H (40.8–42.1%), O···H (19.7–23.9%), S···H (11.1–13.8%), and C···H (11.9–12.1%) contacts were the most common intermolecular interactions in the crystal. Density functional theory (DFT) calculations were used to perform the charge population analysis and simulate the experimental NMR chemical shifts. Compound 4 was also evaluated in silico against dihydrofolate reductase to elucidate the binding mechanism and orientation around the active sites. [ABSTRACT FROM AUTHOR]

This study reports, 35 novel rhodanine, its bioisosteres thiazolidinediones and is tested for EGFR inhibition. These molecules are designed by using a pharmacophore-based superimpose approach taking Gefitinib as a core structure or reference. All the designed molecules were synthesized from 3-chloro and 4-fluoro substituted aniline as the precursors and converted to corresponding dithiocarbamate (3a, b) by reacting with carbon disulfide in presence of ammonia. Further, it was cyclized to rhodanine (4a, b) and subjected to Knoevenagel condensation to find compounds 5(a-j) and 6(a-i). All the compounds are analyzed and from the NMR results, we found that Knoevenagel condensed products are of "Z" geometrical isomers. Further, rhodanine was converted to its bioisosteric form thiazolidinedione by reacting it with a catalytic amount of diacetoxy-iodobenzene in presence of alcohol. All the synthesized compounds are characterized by IR, 1H NMR, 13C NMR, and Mass analysis, and screened for their EGFR inhibition, among all the synthesized compounds, compound 5i, 6 h, 7c, and 8f showed promising results by inhibiting EGFR at <10 nM. Further, structure-activity relationships were established via CoMSIA studies. A series of 35 novel rhodanine, its bioisosteres thiazolidinediones were synthesized by taking 4-fluoro and 3-chloro aniline as a precursors and different aldehydes via Knoevenagel condensation. The synthesized compounds were subjected to In vitro EGFR assay. All the compounds showed a comparable biological activity compared to the standard drug. Additionally, molecular docking and CoMSIA study were performed to support the hypothesis. [ABSTRACT FROM AUTHOR]

Polyethyleneimine and carbon disulfide were employed to modify alkaline lignin (AL) in order to introduce -NH, -NH2 and -CSS- groups. Its adsorption performance towards Cu(II) was evaluated based on the residual concentration (Cr) against the discharge permissible concentration for Cu(II) (2.0 mg/L) established by the World Health Organization. The evaluation was operated under different conditions such as adjusting the solution pH, Cu(II) coexisting with K(I), Na(I), Ca(II) or Mg(II), changing the contact time (t) and initial concentration of Cu(II) (C0), as well as regeneration. When t and C0 equaled to 180 min and 50 mg/L, Cr was less than 2.0 mg/L at pH of 5.03 to 5.65. Under the situation of Cu (II) coexisting with 50 mg/L of K(I), Na(I), Ca(II) or Mg(II), Cr was as low as 1.96, 1.53, 1.97 or 1.55 mg/L (t = 180 min, C0 = 50 mg/L), respectively. Even the modified AL was regenerated and reused four times, Cr was closed to 2 mg/L for each time (t = 180 min, C0 = 51 mg/L). By comparing with other lignin-based materials according to the adsorption equilibrium time, the maximum adsorption capacity, and Cr, the modified AL exhibited higher application potential in copper-loaded water treatment. [ABSTRACT FROM AUTHOR]

Using a reaction between secondary amines, sodium hydroxide, and carbon disulfide followed by introducing methyl iodide into the reaction mixture, we synthesized and characterized a number of dialkyldithiocarbamic acid methyl esters that contained n-alkyl and iso-alkyl groups (C2–C5). Tribological performance data were obtained for the compounds synthesized as they were added to synthetic lubricants. The additives were demonstrated to markedly improve the antiwear, antiseizure, and antifriction properties of the resultant lubricating compositions. The effects of the concentration and structure of the esters on the friction and wear parameters of the lubricants were investigated. [ABSTRACT FROM AUTHOR]

Copyright of Energy Chemical Industry is the property of Energy Chemical Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The objective of this study was to characterize and compare the dry-aging flavor precursors and their liberation mechanisms in beef aged with different methods. Thirteen paired loins were collected at 5 days postmortem, divided into four sections, and randomly assigned into four aging methods (wet-aging (WA), conventional dry-aging (DA), dry-aging in a water-permeable bag (DWA), and UV-light dry-aging (UDA)). All sections were aged for 28 days at 2 °C, 65% RH, and a 0.8 m/s airflow before trimming and sample collection for chemical, metabolomics, and microbiome analyses. Higher concentrations of free amino acids and reducing sugars were observed in all dry-aging samples (p < 0.05). Similarly, metabolomics revealed greater short-chain peptides in the dry-aged beef (p < 0.05). The DWA samples had an increase in polyunsaturated free fatty acids (C18:2trans, C18:3n3, C20:2, and C20:5; p < 0.05) along with higher volatile compound concentrations compared to other aging methods (aldehyde, nonanal, octanal, octanol, and carbon disulfide; p < 0.05). Microbiome profiling identified a clear separation in beta diversity between dry and wet aging methods. The Pseudomonas spp. are the most prominent bacterial species in dry-aged meat, potentially contributing to the greater accumulation of flavor precursor concentrations in addition to the dehydration process during the dry-aging. Minor microbial species involvement, such as Bacillus spp., could potentially liberate unique and potent flavor precursors. [ABSTRACT FROM AUTHOR]

[Display omitted] • Lignin valorization with a novel "waste treatment with waste" concept. • Bifunctional nanocomposites were fabricated with lignin-derived carbon and MoS 2. • Excellent removal capacity of Pb(II) and MB by activating peroxymonosulfate. • The adsorption capacity of Pb(II) by Fe 3 O 4 /PLC-MoS 2 achieved 236.1 mg/g. • Fe 3 O 4 /PLC-MoS 2 degraded MB within 20 min with a degradation rate up to 90.0 %. The development of inexpensive and robust bifunctional nanocomposites toward efficient pollutant removal is crucial for wastewater remediation. Herein, we report a novel strategy for fabrication of magnetic nanocomposites loaded with molybdenum disulfide (Fe 3 O 4 /PLC-MoS 2) using lignin biomacromolecules for efficient pollutant removal. The Fe 3 O 4 /PLC-MoS 2 exhibit excellent pollutant removal capacity: The adsorption capacity of Pb(II) achieve 236.1 mg/g and the methylene blue (MB) degradation rate is up to 90.0 % within 20 min. The adsorption mechanism reveal that the enhanced removal properties is due to that the S atoms on the loaded MoS 2 could convert into soluble sulfide and react with Pb(II) to form white precipitate β-Pb 3 O 2 SO 4. Moreover, the experiments results demonstrate that the Fe 3 O 4 /PLC-MoS 2 has a low bandgap, which can activate PMS to produce reactive oxygen species and degrade MB molecules efficiently. Notably, the Fe 3 O 4 /PLC-MoS 2 demonstrate continued outstanding wastewater remediation capabilities even in scenarios where Pb(II) and MB coexisted. Overall, this study offers a viable and eco-friendly design of dual function removal material by using lignin waste toward promising implications for wastewater treatment. [ABSTRACT FROM AUTHOR]

The overview presented here has the goal of examining whether carbon disulfide (CS2) may play a role as an endogenously generated bioregulator and/or has therapeutic value. The neuro- and reproductive system toxicity of CS2 has been documented from its long-term use in the viscose rayon industry. CS2 is also used in the production of dithiocarbamates (DTCs), which are potent fungicides and pesticides, thus raising concern that CS2 may be an environmental toxin. However, DTCs also have recognized medicinal use in the treatment of heavy metal poisonings as well as having potency for reducing inflammation. Three known small molecule bioregulators (SMBs) nitric oxide, carbon monoxide, and hydrogen sulfide were initially viewed as environmental toxins. Yet each is now recognized as having intricate, though not fully elucidated, biological functions at concentration regimes far lower than the toxic doses. The literature also implies that the mammalian chemical biology of CS2 has broader implications from inflammatory states to the gut microbiome. On these bases, we suggest that the very nature of CS2 poisoning may be related to interrupting or overwhelming relevant regulatory or signaling process(es), much like other SMBs.

Carbon disulfide (CS2) is a highly volatile neurotoxic species. It is known to cause atherosclerosis and coronary artery disease and contributes significantly to sulfur-based pollutants. Therefore, effective detection and capture of carbon disulfide represents an important aspect of research efforts for the protection of human and environmental health. In this study, we report the synthesis and characterization of two strongly luminescent and robust isoreticular metal organic frameworks (MOFs) Zr6(µ3-O)4(OH)8(tcbpe)2(H2O)4 (here termed 1) and Zr6(µ3-O)4(OH)8(tcbpe-f)2(H2O)4 (here termed 2) and their use as fluorescent sensors for the detection of carbon disulfide. Both MOFs demonstrate a calorimetric bathochromic shift in the optical bandgap and strong luminescence quenching upon exposure to carbon disulfide. The interactions between carbon disulfide and the frameworks are analyzed by in-situ infrared spectroscopy and computational modelling by density functional theory. These results reveal that both the Zr metal node and organic ligand act as the preferential binding sites and interact strongly with carbon disulfide.

The release of carbon disulfide can have adverse effects on our environment and human health. The stability of carbon disulfide and the slow kinetics of hydrolysis can make it challenging to achieve efficient and practical cleavage of the C S bonds. Herein, a calix[4]arene-based porous organic polymer (CPOP-1) is innovatively synthesized through an optimized polycondensation reaction using C-Methylcalix[4]resorcinarene and hexafluoro-hexaazatriphenylene as monomers. Subsequently, palladium-induced calix[4]arene-based porous organic polymer was also synthesized via strong Pd−N coordination bonds to construct the metal-induced porous catalyst (CPOP-2). The polymeric catalyst active center [Pd2+(N^N)(NO 3 -) 2 ] demonstrated outstanding catalytic hydrolysis performance (11.14 μmol g-1 h-1) in 10.5 h which is significantly enhanced by ca.13.2 times as compared to reported mononuclear Bpy-Pd(NO 3) 2 , and 7.07 times than model trinuclear complex catalyst HATN-Pd-1, respectively. The control experiments revealed that POP catalysts showcased robust stability, prolonged effectiveness, and feasible recyclability during the hydrolytic cleavage of carbon disulfide at room temperature in aqueous solutions. Furthermore, the coordination environment of [Pd2+(N^N)] was validated through XPS, EXAFS, and isotope labeling measurements, and the hydrolysis cleavage products were confirmed e. g. CO 2 , sulfide, and protons. More importantly, a reaction mechanism was formulated coupled with theoretical calculations, and simulations. The proposed mechanism involves sequential OH- nucleophilic attacks on the carbon atoms of insert-coordinated CS 2 and COS, leading to the cleavage of double C S bonds and the formation of C O bonds. The concurrent dissociation of the C−S bond and liberation of CO 2 result in an intermediate structure characterized by [(N^N)Pd2+](SH-) 2. This intermediate motif serves as the source of the thermodynamic driving force for the reaction. [Display omitted] • Successfully catalytic hydrolysis of CS 2 and COS at room temperature and pressure. • Developed a novel metal-organic catalyst for heterogeneous catalytic reactions. • Enhanced catalytic hydrolysis efficiency (13.2 times) by adjusting the structure. • Realized the rapid separation of catalytic products and recycling of catalysts. • A feasible catalytic mechanism in heterogeneous reaction systems has been proposed. [ABSTRACT FROM AUTHOR]

Experimental studies on the pyrolysis of sulfur mustard (HD) were conducted from 673 to 1473 K using Py-GC/MS combined with two separate columns. The HD pyrolysis rate exceeded 99 % at a pyrolysis time of approximately 2 seconds above 1073 K. The pyrolysis products of HD mainly include ethylene, vinyl chloride, carbon disulfide, thiophene, hydrogen chloride and hydrogen sulfide. The main reaction mechanism of HD pyrolysis was investigated using quantum chemistry methods combined with the TST/VTST theory. At 673 K, the initial reaction pathway of HD primarily involves an intramolecular HCl elimination and the cleavage of the C-S bond. The radical reactions will dominate the pyrolysis of HD once radical pool is formed. The reaction pathways of the important radical intermediates were analyzed, and the formation mechanisms of the main pyrolysis products were investigated. Theoretically, the high-pressure limit rate constants for the major reactions were calculated. This study contributes to a deeper understanding of the HD pyrolysis mechanism and provides a theoretical and data foundation for the destruction of HD. • The pyrolysis products of sulfur mustard were qualitatively and semi-quantitatively analyzed by Py-GC/MS. • The initial reaction pathways and primary radical reactions were investigated through theoretical calculations. • The formation and degradation pathways of key intermediates, and the formation mechanisms of the major products were studied. • This study provides a theoretical and data foundation for the destruction of sulfur mustard. [ABSTRACT FROM AUTHOR]

Exposure to carbon disulfide (CS 2) is a recognized risk factor in the pathogenesis of Parkinson's disease, yet the underlying mechanisms of deleterious effects on mitochondrial integrity have remained elusive. Here, through establishing CS 2 exposure models in rat and SH-SY5Y cells, we demonstrated that highly expressed α-synuclein (α-Syn) is transferred to mitochondria via membrane proteins such as Tom20 and leads to mitochondrial dysfunction and mitochondrial oxidative stress, which ultimately causes neuronal injury. We first found significant mitochondrial damage and oxidative stress in CS 2 -exposed rat midbrain and SH-SY5Y cells and showed that mitochondrial oxidative stress was the main factor of mitochondrial damage by Mitoquinone intervention. Further experiments revealed that CS 2 exposure led to the accumulation of α-Syn in mitochondria and that α-Syn co-immunoprecipitated with mitochondrial membrane proteins. Finally, the use of an α-Syn inhibitor (ELN484228) and small interfering RNA (siRNA) effectively mitigated the accumulation of α-Syn in neurons, as well as the inhibition of mitochondrial membrane potential, caused by CS 2 exposure. In conclusion, our study identifies the translocation of α-Syn to mitochondria and the impairment of mitochondrial function, which has important implications for the broader understanding and treatment of neurodegenerative diseases associated with environmental toxins. [Display omitted] • Mitochondrial oxidative stress mediates mitochondrial damage and neuronal injury resulting from CS 2 exposure. • CS 2 exposure induces mitochondrial translocation of α-Syn, which is associated with Tom20. • Inhibition of α-Syn effectively alleviates CS 2 -induced mitochondrial damage. [ABSTRACT FROM AUTHOR]

Smart sensing devices with high reliability and self-powering features are critical for future-generation wearable applications. In this study, a MoS 2 –carbon nanofiber (CNF) piezoelectric nanogenerator (PENG) was fabricated using MoS 2 nanocrystals. The fabricated MoS 2 –CNFs device was used as a sensor for harvesting diverse deformation energies, demonstrating its high potential as an actuating and sensing material. The microstructure and morphology of the MoS 2 –CNFs were examined via X-ray diffraction, Raman spectroscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). These investigations confirmed the successful synthesis of monolayer MoS 2 nanocrystalline structure with a size of 6 nm and uniform distribution. Further, the presence of monolayer MoS 2 nanocrystalline structure enhanced the conductivity of CNFs, thereby improving its self-powering functionality and piezoelectric properties. The MoS 2 –CNFs composite achieved a maximum output voltage amplitude of 850 mV under applied bending deformation. This research offers a new approach for developing piezoelectric nanofibrous devices and energy-harvesting systems. [Display omitted] [ABSTRACT FROM AUTHOR]

• A novel photocatalytic synthesis of (un)symmetrical ureas and benzimidazolones has been developed. • Carbon disulfide and oxygen serve as the carbonyl sources, eliminating the need for additional oxidants. • Control experiments with oxygen-18 labeling have been conducted to propose a reaction mechanism. • The study contributes to green chemistry by offering an environmentally friendly approach to urea synthesis. A novel photocatalytic urea synthesis strategy is proposed for the preparation of ureas from amines and carbon disulfide (CS 2), with Rhodamine B utilized as the photocatalyst. Conducted under mild reaction conditions, this method does not require the use of extra oxidants and efficiently yields a series of (un)symmetrical ureas and benzimidazolones under blue light irradiation. Furthermore, control experiments with oxygen-18 labeling have been conducted, which demonstrate that the carbonyl oxygen in the urea products is predominantly derived from the oxygen in the air through an oxidative desulfurization process. [Display omitted] [ABSTRACT FROM AUTHOR]

[Display omitted] • A novel adsorption model for the mixture of odor compounds and VOCs was proposed. • The adsorption capacity of CS 2 on activated carbon was only 10% of that of toluene. • Pores smaller than 0.71 nm were responsible for CS 2 adsorption on activated carbon. • Pores smaller than 2 nm determined the adsorption of toluene on activated carbon. • The replacement ratio of CS 2 capacity by high-concentration toluene was constant. The coexistence of volatile organic compounds (VOCs) and odor compounds is a prevalent feature in various industrial exhaust gases. However, a precise mathematical model for the co-adsorption of these pollutants on activated carbon is currently lacking. This study introduces a correction factor to enhance the Langmuir model and investigates its relationship with the pore size distribution of activated carbon through experimental methods. The adsorption behaviors of carbon disulfide (CS 2) and toluene on 14 activated carbon samples were thoroughly examined. The findings indicate that micropores smaller than 0.71 nm predominantly influence CS 2 adsorption, while micropores smaller than 2 nm significantly impact toluene adsorption. Accordingly, the Langmuir competitive adsorption model can be refined by introducing the ratio of competitive adsorption pore volume to individual adsorption pore volume. The resulting corrected predictive model demonstrates a significantly improved correlation with experimental results. The modified model's applicability was extended to universal multicomponent adsorption systems. Furthermore, the study reveals that the replacement ratio of CS 2 adsorption capacity by high-concentration toluene is approximately 24.8, and the roll-up proportion of CS 2 from activated carbon can be estimated by dividing the adsorption capacity of toluene by 521 mg/g. This investigation not only elucidates competitive adsorption patterns in gas and solid phases but also unveils mechanisms within micropores, providing valuable insights into the competitive adsorption process between CS 2 and toluene. These insights are crucial for optimizing fixed bed adsorbers used in odor compounds and VOCs emission control. [ABSTRACT FROM AUTHOR]

We present a numerical investigation of the generation of an ultra-broadband optical similariton spectrum in a photonic crystal fiber (PCF) with a carbon disulfide core through Raman amplification. The proposed PCF has an extremely high nonlinear coefficient of 4519 W−1km−1 at a telecommunication wavelength of 1550 nm and exhibits near-zero ultraflattened normal dispersion of −1.5(ps/nm/km) as well as low confinement loss of about 10−9 dB/m at 1550 nm. The numerical study was conducted using full vectorial finite-element method with a circular perfectly matched layer as a boundary condition. The similariton generated in the proposed PCF has an ultra-broadband and flat spectrum centered at 1550 nm, which spans from 1383 to 1719 nm via 14 mW input peak power and over a fiber length of only 83 cm. This continuum spectrum covers both C and L bands and can be divided into several narrow bands centered at the wavelengths of the wavelength division multiplexing channels. [ABSTRACT FROM AUTHOR]

• The IC 50 value of CS 2 to nitrifying sludge is 3.57 mg/L. • Prolonged CS 2 stress enhances soluble extracellular polymeric substance secretion. • CS 2 reduces nitrifying Rhodanobacter and boosts sulfur-oxidizing Sinomonas. • Multi-omics analysis reveals the inhibitory mechanism of CS 2 on nitrifying sludge. • CS 2 alters pantothenate, CoA biosynthesis, purine, and glutathione metabolism. Carbon disulfide (CS 2) is a widely used enzyme inhibitor with cytotoxic properties, commonly employed in viscose fibers and cellophane production due to its non-polar characteristics. In industry, CS 2 is often removed by aeration, however, residual CS 2 may enter the wastewater treatment plants, impacting the performance of nitrifying sludge. Currently, there is a notable dearth of research on the response of nitrifying sludge to CS 2 -induced stress. This study delves into the alterations in the performance of nitrifying sludge under short-term and long-term CS 2 stress, scrutinizes the toxic effects of CS 2 on microbial cells, elucidates the succession of microbial community structure, and delineates changes in microbial metabolic products. The findings from short-term CS 2 stress revealed that low concentrations of CS 2 induced oxidative stress damage, which was subsequently repaired in cells. However, at concentrations of 100–200 mg/L, CS 2 inhibited reactive oxygen species, superoxide dismutase, and catalase, which are associated with metabolic and antioxidant activities. The inhibition of nitrite oxidoreductase activity by high concentrations of CS 2 was attributed to its impact on the enzyme's conformation. Prolonged CS 2 stress resulted in an increase in the secretion of soluble extracellular polymeric substances in sludge, while CS 2 was assimilated into sulfate. The analysis of sludge microbial community structure revealed a decline in the relative abundance of Rhodanobacter, which is associated with nitrification, and an increase in Sinomonas, involved in sulfur oxidation. Metabolite analysis results demonstrated that high concentrations of CS 2 affect pantothenate and CoA biosynthesis, purine metabolism, and glutathione metabolism. This study elucidated the microbial response mechanism of nitrifying sludge under short-term and long-term CS 2 stress. It also clarified the composition and function of microbial ecosystems, and identified key bacterial species and metabolites. It provides a basis for future research to reduce CS 2 inhibition through approaches such as the addition of metal ions, the selection of efficient CS 2 -degrading strains, and the modification of strain metabolic pathways. [Display omitted] [ABSTRACT FROM AUTHOR]

Reactivity of borate ligand derived from CS 2 with κ2- N,S -chelated ruthenium borate complexes, [Ph 3 P(κ2- N,S -L)Ru{κ3- H,S,S ′-H 2 B(L) 2 }], (L = C 7 H 4 NS 2 , C 5 H 4 NS) has been demonstrated that led to the formation of ruthenium dithioformate and trithia-borinane complexes. [Display omitted] The reactivity of κ2 - N,S -chelated ruthenium borate complexes, [Ph 3 P(κ2 - N,S -L)Ru{ κ3 - H,S,S ′-H 2 B(L) 2 }], (L = C 5 H 4 NS, C 7 H 4 NS 2) 1 and 3 with borate ligand derived from CS 2 has been investigated. The thermolysis of [Ph 3 P(κ2 - N,S -C 5 H 4 NS)Ru{ κ3 - H,S,S ′-H 2 B(C 5 H 4 NS) 2 }], 1 with Na[BH 3 (SCHS)] led to the formation of ruthenium dithioformate complexes, [PPh 3 (κ3 - H,S,S ′-H 2 B(C 5 H 4 NS)}Ru{(η 2-SCHS)}], trans- 2 and [PPh 3 (κ3 - H,S,S ′-H 2 B(C 5 H 4 NS)}Ru{(η 2-SCHS)}], cis- 2. Further, to study the reactivity of the same borate ligand derived from CS 2 , we have performed the reaction of [Ph 3 P(κ2 - N,S -C 7 H 4 NS 2)Ru{ κ3 - H,S,S ′-H 2 B(C 7 H 4 NS 2) 2 }], 3 with Na[BH 3 (SCHS)] that yielded ruthenium dithioformate, [Ph 3 P(κ2 - N,S -C 5 H 4 NS)Ru{(η 2-SCHS)}], cis- 4 and 1,3,5-trithia-2-borinane, [PPh 3 Ru{ κ3 - H,S,S′ -H 2 B(NC 7 H 4 S 2) 2 }]{(SCH 2) 2 SBH}], 5 complexes. All these studies show that cis- 4 is analogous to trans- 2 and cis- 2. The solid-state X-ray structure of 5 shows that the ruthenium center is stabilized by diborate, phosphine and six-membered ruthenacycle [RuSBNCS] ring that is fused with a {C 2 S 3 B} ring. The synthesized complexes have been thoroughly characterized by various spectroscopic techniques and single-crystal X-ray diffraction analysis of trans- 2 , cis- 2 and 5. Density functional theory (DFT) calculations further provided an insight into the electronic structures of the complexes. [ABSTRACT FROM AUTHOR]

[Display omitted] • The multicomponent polymerization of diamines, CS 2 , and diacrylates. • The synthesized polydithiourethanes could be efficiently degraded via aminolysis. • The prepared polydithiourethanes networks could be reprocessed. In the pursuit of advanced functional polymer materials, sulfur-containing polymers have received tremendous attention owing to their superior chemical stability, high refractive indices, various supramolecular interactions, and robust dynamic covalent chemistry. However, their synthesis usually involves either expensive monomers or toxic byproducts and requires catalysts, thus hindering their widespread application. In this work, we present a catalyst-free multicomponent polymerization in organic solvents for the synthesis of various polydithiourethanes with excellent yields (up to 98 %) and high molecular weights (up to 112 kg/mol). This reaction involves the direct polymerization of carbon disulfide, an abundant one-carbon feedstock, with commercially available diamines and diacrylates. This polyaddition process demonstrates high atom economy and no byproduct, occurring at room temperature without the need for a catalyst, thus exhibiting excellent green chemistry metrics. By utilizing the dynamic covalent chemistry of dithiourethane groups, these polymers can be efficiently degraded via aminolysis and used to fabricate reprocessable vitrimers. This multicomponent polymerization opens up a new avenue for the efficient utilization of carbon disulfide resources and accelerates the exploration of diversified sulfur-containing functional polymer materials. [ABSTRACT FROM AUTHOR]

Alex J. Plajer, a Juniorprofessor at the University of Bayreuth in Germany, recently published his first article as a submitting corresponding author in Angewandte Chemie. The article, titled "Ring‐Opening Terpolymerisation of Elemental Sulfur Waste with Propylene Oxide and Carbon Disulfide via Lithium Catalysis," explores polymer synthesis and polymerization catalysis. Plajer emphasizes the importance of scientific freedom during his PhD, which gave him the confidence to pursue an independent career. He also highlights the challenges of the volume of knowledge generated in modern science and the need for interdisciplinary research. Plajer's favorite saying is "Failure is success in progress," and he enjoys weightlifting, following sports, and traveling in his free time. [Extracted from the article]

Maternal solvent exposure has been suspected to increase offspring cancer risk. The study aimed to evaluate the associations between maternal residential exposure to solvents from industrial pollution during pregnancy and childhood cancer. The present study included 15,744 cancer cases (aged 0–19 years at diagnosis) identified from California Cancer Registry and 283,141 controls randomly selected from California Birth Registry (20:1 frequency-matched by birth year: 1998–2016). We examined industrial releases of tetrachloroethylene and 1,1,1-trichloroethane within 3 km of the birth address, while we used a 5 km buffer for carbon disulfide. We calculated the total exposure from all linked Toxic Release Inventory sites during each index pregnancy and assigned "ever/never" and "high/low exposed/unexposed" exposure, using median values. We performed quadratic decay models to estimate cancer risks associated with maternal solvent exposure in pregnancy. 1,1,1-Trichloroethane was associated with rhabdomyosarcoma (adjusted Odds Ratio (aOR): 1.96; 95% Confidence Interval (CI): 1.16, 3.32) in the "ever exposed" group. Ever exposure to carbon disulfide was associated with increased risks of medulloblastoma (OR = 1.85, 95% CI 1.01, 3.40) and ependymoma (OR = 1.63, 95% CI 0.97, 2.74). Overall, our findings suggested maternal residential exposure to solvents from industrial sources might be associated with elevated childhood cancer risks. [ABSTRACT FROM AUTHOR]

Organodisulfides (RSSR) are a class of promising active materials for redox flow batteries (RFBs). However, their sluggish kinetics and poor cyclic stability remain a formidable challenge. Here, we propose carbon disulfide (CS2) as a unique redox mediator involving reversible C-S bond formation/breakage to facilitate the reduction reaction of organodisulfides in RFBs. In the discharge of RSSR, CS2 interacts with the negatively charged RSSR-• to promote cleavage of the S-S bond by reducing about one-third of the energy barrier, forming RSCS2Li. In the recharge, CS2 is unbonded from RSCS2Li while RSSR is regenerated. Meanwhile, the redox mediator can also be inserted into the molecular structure of RSSR to form RSCS2SR/RSCS2CS2SR, and these new active materials with lower energy barriers can further accelerate the reaction kinetics of RSSR. With CS2, phenyl disulfide exhibits an exceptional rate capability and cyclability of 500 cycles. An average energy efficiency of >90% is achieved. This strategy provides a unique redox-mediating pathway involving C-S bond formation/breakage with the active species, which is different from those used in lithium-oxygen or other batteries. [ABSTRACT FROM AUTHOR]

The adsorption properties of carbon disulfide (CS2) and hydrogen sulfide (H2S) gas molecules on hex-star phosphorene nanosheet (hex-star PNS) are studied. Initially, the structural stability of hex-star PNS is ensured based on phonon band structure and formation energy. The hex-star PNS possesses an energy band gap of 1.393 eV. Besides, upon adsorption of CS2 and H2S on hex-star PNS, the changes in the electronic properties are noticed through electron density difference, band structure, and density of states spectrum. The CS2 and H2S are physisorbed on hex-star PNS, confirming the reversibility of base material. Hence, the results suggest the deployment of hex-star PNS as a sensing substrate toward CS2 and H2S molecules. [ABSTRACT FROM AUTHOR]

Rationale: Building on our report that collision-induced dissociation (CID) can be used to create the highly reactive U-alkylidyne species [O=U≡CH]+, our goal was to determine whether the species could be as an intermediate for synthesis of [OUS]+ by reaction with carbon disulfide (CS2). Methods: Cationic uranyl-propiolate precursor ions were generated by electrospray ionization, and multiple-stage CID in a linear trap instrument was used to prepare [O=U≡CH]+. Neutral CS2 was admitted into the trap through a modified He inlet and precision leak valves. Results: The [O=U≡CH]+ ion reacts with CS2 to generate [OUS]+. CID of [OUS]+ causes elimination of the axial sulfide ligand to generate [OU]+. Using isotopically labeled reagent, we found that [OUS]+ reacts with O2 to create [UO2]+. Conclusions: [O=U≡CH]+ proves to be a useful reagent ion for synthesis of [OUS]+, a species that to date has only been created by gas-phase reactions of U+ and U2+. Dissociation of [OUS]+ to create [OU]+, but not [US]+, and the efficient conversion of the species into [UO2]+, is consistent with the relative differences in U-O and U-S bond energies. [ABSTRACT FROM AUTHOR]

Rationale: Building on our report that collision-induced dissociation (CID) can be used to create the highly reactive U-alkylidyne species [O=U≡CH]+, our goal was to determine whether the species could be as an intermediate for synthesis of [OUS]+ by reaction with carbon disulfide (CS2). Methods: Cationic uranyl-propiolate precursor ions were generated by electrospray ionization, and multiple-stage CID in a linear trap instrument was used to prepare [O=U≡CH]+. Neutral CS2 was admitted into the trap through a modified He inlet and precision leak valves. Results: The [O=U≡CH]+ ion reacts with CS2 to generate [OUS]+. CID of [OUS]+ causes elimination of the axial sulfide ligand to generate [OU]+. Using isotopically labeled reagent, we found that [OUS]+ reacts with O2 to create [UO2]+. Conclusions: [O=U≡CH]+ proves to be a useful reagent ion for synthesis of [OUS]+, a species that to date has only been created by gas-phase reactions of U+ and U2+. Dissociation of [OUS]+ to create [OU]+, but not [US]+, and the efficient conversion of the species into [UO2]+, is consistent with the relative differences in U-O and U-S bond energies. [ABSTRACT FROM AUTHOR]

A metal and base‐free, operationally simple, and scalable multicomponent approach towards the synthesis of S‐diarylmethane dithiocarbamates is reported. A range of structurally and electronically diverse p‐quinone methides are shown to react with a variety of amines, and carbon disulfide to furnish corresponding dithiocarbamates in good to excellent yields under mild conditions. Furthermore, p‐QMs embedded with aliphatic substituents are well accommodated. Importantly, these readily accessible compounds demonstrated promising anti‐proliferative activity in the low micromolar ranges in lung adenocarcinoma cells, reiterating the importance of the developed methodology. [ABSTRACT FROM AUTHOR]