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A recent study conducted in Orebro, Sweden, explored the effectiveness of Botulinum toxin Type A (BTX-A) injections in managing jaw myalgia. The research, funded by various organizations, found that a single session of BTX-A injections did not significantly reduce functional jaw pain compared to a placebo. The study suggests that further research with a larger sample size may be needed to determine the efficacy of BTX-A in treating jaw myalgia. [Extracted from the article]

A recent report from the University of Orebro in Sweden discusses the use of serum proteomics to characterize the heterogeneity of Inflammatory Bowel Disease (IBD). The study aimed to identify discriminative patterns of biological subtypes across multiple European cohorts by measuring inflammation-related serum proteins in IBD patients and healthy controls. The findings suggest a continuous IBD spectrum rather than a clear separation between Crohn's disease and ulcerative colitis, with disease location potentially reflecting more similarity than the traditional CD versus UC classification. [Extracted from the article]

A recent study conducted by Orebro University in Sweden focused on the effectiveness of tailored internet-delivered cognitive behavior therapy (ICBT) for depression in older adults aged 65 years and older. The research found that ICBT was superior to an active control group in reducing depression levels, as measured by the Geriatric Depression Scale (GDS-15) and Beck Depression Inventory (BDI-II). The study concluded that ICBT can be a valuable tool in increasing access to psychotherapy for older adults with depression. [Extracted from the article]

A study conducted at the University of Orebro in Sweden focused on the importance of physical activity for older adults, who are often one of the least active groups in society. The research aimed to understand what health resources older adults find meaningful for participation in organized sports, with a focus on health-promoting perspectives within sports clubs. The study involved over 4,800 older adults participating in Swedish sports clubs, revealing differences in what men and women of different ages found meaningful in physical activities. The research has been peer-reviewed and provides valuable insights into promoting physical activity among older adults. [Extracted from the article]

A study conducted in Sweden examined healthcare resource use, treatment patterns, and costs for children with controlled and uncontrolled atopic dermatitis (AD). The research included 8,922 children aged 0-17 diagnosed with AD between 2015 and 2018. Findings showed that uncontrolled AD was associated with higher healthcare utilization and costs compared to controlled disease, with a mean annual healthcare cost of (EURO)4,479.5 per child. The study suggested that a significant number of children with AD may be undertreated, particularly adolescents with uncontrolled AD, emphasizing the need for more effective treatment strategies. [Extracted from the article]

A study conducted at the University of Orebro in Sweden focused on Swedish prison officers' perceptions of management and support at work. The research identified 10 key predictors for overall prison regime evaluation and found three distinct subgroups within the sample. The study highlighted the importance of intra-organizational social support, communication, and loyalty in enhancing prison officers' job satisfaction. The findings suggest that improving collegial, management, and supervision support may lead to increased job satisfaction among prison officers in Sweden. [Extracted from the article]

A recent study from the University of Orebro in Sweden explores the early twentieth-century marketing strategies of Postum, a roasted wheat bran drink, as a substitute for coffee in response to concerns about 'coffee abuse.' The research analyzes 200 advertisements from 1926 to 1940 in Svenska Dagbladet, highlighting how Postum capitalized on public fears about coffee by positioning itself as a healthier alternative. By manipulating scientific and medical knowledge on caffeine, Postum marketed itself as a solution to health issues like neurasthenia, insomnia, and digestive disorders, tapping into broader discourses of wellbeing and productivity in food marketing. This peer-reviewed research sheds light on historical advertising practices and their impact on consumer perceptions of health and wellness. [Extracted from the article]

A recent study conducted at Orebro University in Sweden examined the experiences of different professionals in occupational health services regarding workplace psychological and social factors. The study included 472 respondents from various professions in the field, revealing that while experiences varied, overall satisfaction with the work environment was reported. Approximately 7% of respondents reported witnessing harassment or bullying in the workplace within the last six months. The research suggests a need for further investigation and development of occupational health services in Sweden. [Extracted from the article]

A study conducted at the University of Orebro in Sweden compared the performance of a targeted absolute quantification isotope dilution liquid chromatography tandem mass spectrometry assay with a commercial nontargeted relative quantification assay for detecting major perfluoroalkyl substances (PFAS) in human blood. The research found that the two assays showed strong correlations for three major PFAS, with high agreement in results. The study concluded that the nontargeted approach could be valid for correlating PFAS levels with various health phenotypes, providing additional confidence in its use. The research was supported by the Swedish Research Council Formas and has been peer-reviewed. [Extracted from the article]

A study conducted at University Hospital Orebro in Sweden found that implementing prepacked take-home analgesia bags for postoperative pain treatment in outpatient hand surgery significantly reduced the quantity of opioids prescribed. Patients who received these bags consumed 50% less oxycodone in the small bag group and 67% less in the large bag group compared to standard prescriptions. The research concluded that patient satisfaction was high, and postoperative pain levels were acceptable. This study has been peer-reviewed and published in Acta Chirurgiae Orthopaedicae Et Traumatologiae Cechoslovaca. [Extracted from the article]

Researchers from the University of Orebro conducted a study on children's and parents' attitudes and knowledge about HPV vaccination in Sweden following the introduction of gender-neutral HPV vaccination in the national immunization program. The study found that a majority of parents and children received additional information about HPV vaccination and were satisfied with it. Both parents and children considered HPV vaccination important for health and believed in vaccinating all genders. The study highlighted the role of school nurses as a reliable source of information on HPV vaccination, with teachers also playing a significant role in educating children about HPV and vaccination. [Extracted from the article]

Researchers at the University of Orebro in Sweden conducted a study on young adults' participation in a circular deposit-refund scheme for beverage containers. The scheme aimed to influence individuals' decision-making through a deposit-refund incentive, but the study found that many young adults engaged in 'counter earmarking', personal accounting practices that conflicted with the official scheme. The research highlights the challenges of imposing accounting ideologies on individuals within circular waste recovery schemes. This peer-reviewed study provides valuable insights into the role of personal accounting in circular consumer behavior. [Extracted from the article]

A recent study conducted at the University of Orebro in Sweden examined racial disparities in the administration of venous thromboembolism (VTE) prophylaxis in trauma patients. The research found that black patients had the highest rates of VTE prophylaxis exposure, shortest time to administration, and highest use of low molecular weight heparin. While black patients had the highest incidence of deep vein thrombosis and pulmonary embolism, they also had higher administration rates and earlier initiation of VTE prophylaxis compared to other racial groups. Further investigation is needed to understand the underlying causes of these differences. [Extracted from the article]

Researchers at the University of Orebro conducted a study on small-intestinal neuroendocrine tumors (SI-NETs) to evaluate longitudinal changes in Ki-67 indices and their impact on overall survival. The study included 45 patients with well-differentiated tumors, analyzing the progression of Ki-67 indices over time and its correlation with survival outcomes. The research found that an increase in Ki-67 indices and grade progression were associated with worse survival outcomes in approximately one-third of SI-NETs subjected to re-biopsy. The study highlights the importance of monitoring Ki-67 indices in SI-NET patients for better prognostic assessment. [Extracted from the article]

A study conducted at the University of Orebro in Sweden examined the management and outcomes of pancreatic injuries in children. The researchers analyzed data from the Trauma Quality Improvement Program (TQIP) database and found that nonoperative management (NOM) is a viable option for intermediate/high-grade pancreatic injuries in pediatric patients. The study included 580 patients with grade III and IV pancreatic injuries, and the majority of children were managed nonoperatively. The research concluded that NOM is a reasonable strategy for these injuries, resulting in equivalent outcomes and a shorter hospital stay compared to pancreatic drainage or resection. [Extracted from the article]

A recent study conducted in Mozambique evaluated the accuracy of the 4th-generation Alere HIV Combo rapid diagnostic test (RDT) in detecting acute and seroconverted HIV infections among sexually-active women. The study found that the antibody component of the Alere HIV Combo RDT demonstrated a sensitivity and specificity of 100% in examining clinical samples, but it did not detect HIV p24 antigen in any clinical samples. The test also had a low sensitivity in detecting HIV p24 antigen in seroconversion panels. The researchers concluded that there is a need for simple and affordable point-of-care tests with high sensitivity and specificity for diagnosing individuals with acute HIV infection in resource-limited settings with high HIV prevalence. [Extracted from the article]

A recent study conducted at a psychiatric ward in Orebro, Sweden, explored the implementation of the Safewards model, which aims to reduce conflict and containment on psychiatric wards. The study focused on assessing the level of implementation fidelity by examining patient responsiveness to the interventions. The findings indicated high implementation fidelity, with patients reporting improvements in their experiences of care and feeling respected, hopeful, and safe. The study highlights the importance of patient responsiveness in achieving fidelity in prevention programs and suggests that patient input can be valuable in adapting Safewards in practice. [Extracted from the article]

A recent systematic integrative review conducted by researchers at the University of Orebro in Sweden examined existing research on children in domestic violence shelters. The review analyzed 28 scientific articles published between 1984 and 2021 and focused on how shelters contribute to children's life situations after leaving a violent home. The analysis identified five themes: safety and security, health, behavior, and support, schooling, spare time and shelter environment, and social relationships. The research emphasized the importance of prioritizing children's rights to protection from violence, as well as their rights to support, education, recreational time, and social relationships, in order to improve their life situations at shelters. [Extracted from the article]

A recent study conducted by researchers at the University of Orebro in Sweden focused on the Gram-Negative Bacteria Pseudomonas oleovorans and its resistance to biocides. The study examined the impact of biocide exposure on the metabolome of two strains of P. oleovorans. The researchers found that exposure to a specific biocide induced significant metabolic modifications in P. oleovorans, particularly in lipid and metabolite profiles, amino acid metabolism, and stress response pathways. The study suggests that understanding how different substances interact with bacteria is crucial for developing more effective antimicrobial chemicals and combating biocide resistance. [Extracted from the article]

New research conducted at the University of Orebro in Sweden explores the impact of interrupted corneal collagen crosslinking (CXL) treatment on the progression of keratoconus, a condition that causes the cornea to become thin and cone-shaped. The study found that in some cases, debridement of the corneal epithelium and riboflavin administration without intense UVA radiation may slow or arrest the progression of keratoconus. The research suggests that this effect may be due to photosensitization from ambient light. The study included 11 eyes of nine patients, with five eyes showing no signs of progression after interrupted CXL treatment. [Extracted from the article]

A recent study conducted by researchers at the University of Orebro in Sweden explored consumers' attachment to meat and its association with their preferences for plant-based meat alternatives (PBMAs). The study found that consumers with a higher level of meat attachment (HMA) had lower overall liking, aroma liking, and taste liking for PBMAs compared to consumers with a lower level of meat attachment (LMA). However, both LMA and HMA consumers were able to discriminate among the sensory properties of PBMAs and the ideal profile. These findings can be used to inform future research and the development of PBMAs that cater to consumers' meat attachment levels. [Extracted from the article]

A study conducted at the University of Orebro in Sweden explored the relationship between incretin hormones and endogenous 5-hydroxytryptamine in the small and large intestine response. The researchers found that anesthetic agents, specifically dexmedetomidine, can affect esophageal function testing by impacting primary and secondary peristalsis. This effect is likely due to a transient direct alpha 2-mediated effect on esophageal smooth muscle. The research has been peer-reviewed and published in the journal Neurogastroenterology & Motility. For more information, readers can contact the University of Orebro. [Extracted from the article]

A recent study conducted by Orebro University in Sweden found that adolescent girls experience more musculoskeletal pain due to insomnia compared to boys. The study analyzed longitudinal survey data from over 2,700 participants and found that insomnia predicted pain in adolescents, with the effect being 3.5 times larger in girls than boys. The study also revealed that rumination and negative mood mediated the relationship between insomnia and pain, with rumination being a significant mediator for girls and depressed mood being the main mediator for boys. These findings highlight the importance of considering gender differences when studying the relationship between insomnia and pain in adolescents. [Extracted from the article]

A systematic review conducted by researchers at Orebro University in Sweden explored the relationship between placental changes and childhood atopic disorders. The review included 19 studies with a total of 12,997 participants. The findings suggested that histological chorioamnionitis in preterm-born children was associated with asthma-related problems, while a large placenta in term-born children increased the risk of being prescribed anti-asthma medications during the first year of life. Placental histone acetylation, DNA methylation, and gene expression differences were also found to be associated with different atopic disorders in term-born children. However, further studies are needed to validate these findings, control for confounders, and explore potential mechanisms. [Extracted from the article]

A recent study conducted at the University of Orebro in Sweden explores the introduction of bananas to Sweden in the early 20th century and how marketing played a crucial role in shaping the perception and consumption of this new and exotic fruit. The study focuses on advertisements from Fyffes, the dominant banana brand at the time, and analyzes the verbal and visual strategies used to educate Swedish consumers about the health benefits of bananas. The research concludes that marketing played a significant role in transforming knowledge about food and influencing positive attitudes towards bananas in Sweden. This study provides insights into the power of marketing in introducing new foods to a country. [Extracted from the article]

A new report from the University of Orebro in Sweden presents fresh data on obesity, fitness, and wellness. The report discusses Bayesian inference procedures for a multivariate random effects model and its application to real data on the effectiveness of hypertension treatment for reducing blood pressure. The research concludes that the posterior is proper as long as the sample size is larger than the dimension of the data-generating model. The study was supported by various organizations, including the National Institute of Standards and Technology and the Swedish Research Council. [Extracted from the article]

A systematic review conducted by researchers at the University of Orebro in Sweden examined the relationship between recreational noise exposure and hearing function in adolescents and young adults. The review found that while some recreational noise activities can potentially harm hearing, there is an unclear relationship between exposure and outcome. The study highlighted inconsistencies in the methods used to measure exposure and outcome, suggesting that this may contribute to the differing results in studies on the impact of recreational noise exposure on hearing function. The researchers concluded that more longitudinal research is needed to draw more certain conclusions about the long-term effects of recreational noise exposure on hearing function. [Extracted from the article]

A recent study conducted by Orebro University in Sweden investigated the association between electroconvulsive therapy (ECT) and readmission rates after a manic episode in patients with bipolar disorder. The study included all patients diagnosed with bipolar disorder and admitted to any hospital in Sweden between 2012 and 2021. The results showed that ECT was not significantly associated with longer time to readmission, but there was a trend towards a protective effect of ECT when comparing admissions with and without ECT within the same patients. The study highlights the high readmission rates after inpatient treatment of mania. [Extracted from the article]

A report from Orebro University in Sweden discusses the need to promote the mental well-being of forced migrant children and youth, as there are over 40 million displaced children and youth worldwide. The study aimed to synthesize evidence on interventions that increase well-being, resilience, and quality of life, as well as reduce internalizing and externalizing symptoms in this population. The review found that while there is a lack of rigorous intervention studies, the few eligible studies indicate promise. The research concludes that more research is needed in this area. [Extracted from the article]

A recent study conducted by Orebro University in Sweden has found potential factors associated with neurodevelopmental disorders (ND) in children. The study followed a birth cohort for over 20 years and collected data on infection and antibiotic events, stress, prenatal factors, family history, and more. The researchers assessed biomarkers such as cord serum metabolome and lipidome, human leukocyte antigen (HLA) genotype, infant microbiota, and stool metabolome. The study found significant associations between these biomarkers and future ND diagnosis, including intellectual disability, speech disorder, attention-deficit/hyperactivity disorder, and autism. The findings suggest links to immunodysregulation and metabolism, as well as stress, early-life infection, and antibiotics. This research provides a foundation for early-life prediction and intervention in neurodevelopment. [Extracted from the article]

A report from the University of Orebro in Sweden discusses the need for global environmental assessment organizations to include more social scientific knowledge in order to address climate change. The researchers analyzed the IPCC special report on limiting global warming to 1.5 degrees and found that social processes and structures are underdeveloped in these assessments. They argue that significant changes to the current epistemic infrastructure are necessary to integrate this knowledge and promote transformative change. The research suggests that complementary institutional science-policy relations could assist in this process. [Extracted from the article]

A recent study conducted by researchers at the University of Orebro in Sweden evaluated the pharmacodynamics of ceftriaxone single-dose therapy for the treatment of Neisseria gonorrhoeae, a bacteria that causes gonorrhea. The study found that ceftriaxone treatments were effective in eradicating ceftriaxone-susceptible strains of the bacteria, as well as some ceftriaxone-resistant strains. However, higher doses of ceftriaxone were needed to eradicate high-level ceftriaxone-resistant strains. The researchers recommend a ceftriaxone dose of 1 g for first-line empiric gonorrhea treatment, which can help manage the spread of ceftriaxone-resistant strains until new antimicrobials are available. [Extracted from the article]

A recent study conducted at the University of Orebro in Sweden explored the metabolomes of children with new-onset inflammatory bowel disease (IBD) and compared them to symptomatic non-IBD controls. The researchers analyzed colonic and ileal biopsies as well as plasma samples using ultra-performance liquid chromatography-mass spectrometry. The study found that there were differences in the metabolomes of inflamed mucosal biopsies between IBD patients and controls. The findings suggest that there are specific metabolomic signatures associated with IBD, and by integrating these data with clinical and inflammatory markers, potential biomarkers for IBD can be identified. [Extracted from the article]

A recent study conducted at the University of Orebro in Sweden compared external and internal training load markers during an 8-week resistance training program in different oxygen environments. The study found that performing resistance training in hypoxic environments may improve cardiorespiratory response and speed up recovery. The research involved 33 volunteers who were assigned to either normoxia, intermittent hypobaric hypoxia, or intermittent normobaric hypoxia. The study concluded that intermittent resistance training in hypoxic environments could be more time-efficient for improving strength levels in the back squat without causing higher levels of physiological stress. [Extracted from the article]

A recent study from the University of Orebro in Sweden explores the survivorship experiences of women's artistic gymnasts who have experienced child sexual abuse (CSA). The research highlights the importance of survivorship narratives and the role of hearing and telling stories in the healing process. The study emphasizes the need for increased awareness and support for survivors of CSA in the sport of gymnastics. This research provides valuable insights into the experiences of survivors and contributes to the ongoing conversation surrounding child sexual abuse in sports. [Extracted from the article]

A study conducted by researchers at the University of Orebro in Sweden examined the impact of fine-needle aspiration cytology (FNAC) on the extent of surgery and associated surgical morbidity in patients with thyroid cancer. The study analyzed a nationwide cohort of 2,519 patients who underwent surgery for thyroid cancer between 2004 and 2013. The findings showed that FNAC results influenced surgical planning, with intermediate FNAC categories leading to less extensive surgery. The study also found that primary less than total thyroidectomy (LTT) was a safer approach compared to total thyroidectomy (TT) in terms of complications such as recurrent laryngeal nerve (RLN) palsy and permanent hypoparathyroidism. However, completion thyroidectomy in cases of inadequate initial surgery did not result in significant surgical morbidity. The researchers suggest that primary TT should be reserved for larger lesions with suspicion of malignancy. [Extracted from the article]

A study conducted at the University of Orebro in Sweden has explored the development of a probiotic-based vaccine candidate for HIV/AIDS. The researchers used CRISPR/Cas9 editing to introduce the HIV-1 envelope membrane-proximal external region (MPER) into the E. coli Nissle 1917 bacteria. The modified bacteria showed stable expression of the MPER epitope and were recognized by an anti-HIV-1 antibody. The study suggests that this approach could provide a cost-effective and rational method for vaccine antigen expression and administration. [Extracted from the article]

Researchers from the University of Orebro in Sweden have conducted a study comparing two methods for detecting polyfluoroalkyl and perfluoroalkyl substances (PFAS) in human blood. The study found that a commercial nontargeted relative quantification assay provided comparable results to the targeted absolute quantification isotope dilution LC-MS/MS assay. The two assays showed strong correlations and agreement in detecting three major PFAS. The researchers concluded that the nontargeted approach could be a valid method for studying the associations of PFAS with various health phenotypes. [Extracted from the article]