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Objective The aim of this study was to compare the interventional effects of polydatin given by different administration modes on experimental silicosis rats. Methods Fifty SPF SD rats were randomly divided into five groups, namely the control group, silica model group, polydatin inhalation group, polydatin gavage group, and polydatin intraperitoneal injection group. There were 10 rats in each group. Among them, the control group did not have any treatment, the model group was only treated with silica molding, and the other 3 groups were treated with polydatin via different administration methods after silica molding. The general condition of rats in each group and the lung coefficient of each group were observed at 28 days and 56 days after dust treatment. Paraffin sections of rat lung tissue were stained with hematoxylin-eosin (HE) and Masson staining. The kit was used to detect the content of hydroxyproline (HYP) and malondialdehyde (MDA) in the lung tissue of rats in each group, and the degree of lung inflammation and pulmonary fibrosis in each group of rats was evaluated. Results At day 56 after dust exposure, the lung coefficient of rats in the model group was significantly increased (P < 0.001) compared with the control group; compared with the model group, the lung coefficient of rats in the intraperitoneal injection group was decreased (P < 0.05). The results of HE staining of lung tissue of rats in each group showed that the alveolar wall was thin and the alveolar structure was normal in the control group on the 28th and 56th days, and no collapse was seen; compared with the control group on the 28th day, the alveolar wall of the rats in the 28th day model group was significantly thickened, the alveolar septum was widened, and a large number of inflammatory cells infiltrated the alveolar cavity; compared with the 28th day model group, the alveolar structure of each intervention group of polydatin was relatively normal. At day 56, compared with the control group, the alveolar wall of fibroblasts and fibroblast hyperplasia were further thickened in the model group; compared with the model group, the alveolar spacing in the intraperitoneal injection group, gavage group, and nebulized inhalation group was reduced. The Masson staining examination of rat lung tissue showed that, compared with the control group, the lung tissue of the model groups on the 28th and 56th days had blue cord -like collagen fiber hyperplasia. The results of collagen volume analysis showed that on the 28th and 56th days, the collagen volume integration number of the model group increased significantly compared with the control group; compared with the model group, the collagen volume fraction of all three groups of polydatin -treated rats decreased (P < 0.01). Such effects were observed to be more pronounced in rats with the intraperitoneal injection compared to those of the other two groups. On the 56th day after treatment, the content of HYP in the lung tissues in all treated groups increased compared with the control group (P < 0.05); compared with the model group, the content of hydroxyproline decreased in the intraperitoneal injection group, gavage group, and nebulized inhalation group (P < 0.05). On the 28th day after treatment, there was no significant difference in the concentration of malondialdehyde in the serum of each group (P = 0.140). On the 56th day after treatment, compared with the control group, the levels of MDA in the serum of the model group, the gavage group, and the aerosol inhalation group increased (P < 0.05); the content of MDA in the intraperitoneal injection group, gavage group, and nebulized inhalation group decreased (P < 0.05) compared with the model group, among which the MDA content in the intraperitoneal injection group had the best amelioration effect. Conclusions Polydatin, optimally administered by intraperitoneal injection, could effectively decelerate silicosis progression in SD rats, possibly via its anti-inflammatory and anti-fibrotic effects. [ABSTRACT FROM AUTHOR]

Copyright of Occupational Health & Emergency Rescue is the property of Occupational Health & Emergency Rescue Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Engineering Geology / Gongcheng Dizhi Xuebao is the property of Journal of Engineering Geology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Contemporary Pediatrics is the property of Xiangya Medical Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Mine Automation is the property of Industry & Mine Automation Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Geology & Exploration is the property of Xian Research Institute of China Coal Research Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Practical Medicine / Shiyong Yixue Zazhi is the property of Journal of Practical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Takayasu arteritis (TAK) is a kind of chronic non-specific vasculitis. It is commonly treated with glucocorticoids, immunosuppressants and biologic and targeted agents. However, there are still problems of low disease remission rate and continuous progression of vascular lesions. In traditional Chinese medicine, TAK belongs to the category of “pulse bi”. Traditional Chinese medicine played an irreplaceable role in relieving clinical symptoms, improving life quality and disease prognosis, and preventing recurrence. In this review, the authors summarized the pathogenesis, famous traditional Chinese medicine experts' theories and clinical experiences of TAK. The theory of reducing side effects and enhancing anti-inflammation effects was put forward. Based on the combination of different disease stages and syndromes, we integrated treatments of Chinese and western medicine of TAK，so as to form a new treatment model and strategy for improving long-term prognosis of TAK patients. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Data Acquisition & Processing / Shu Ju Cai Ji Yu Chu Li is the property of Editorial Department of Journal of Nanjing University of Aeronautics & Astronautics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Contemporary Pediatrics is the property of Xiangya Medical Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Contemporary Pediatrics is the property of Xiangya Medical Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Research results and literature reports show that the composition and acid hydrolysis process of lignocellulose are systematically reviewed・ The step-by-step operation process of lignocellulose acid hydrolysis is analyzed, and the products of lignocellulose acid hydrolysis under different process conditions are compared・ According to the different types of acids used in acidolysis of lignocellulose, this paper focuses on the use of organic acid, inorganic acid and solid acid to hydrolyze lignocellulose, the optimal process conditions and the yield of the target product. The current problems and future research directions of lignocellulosic acid hydrolysis are put forward to provide a reference for the in-depth study of lignocellulosic biomass. [ABSTRACT FROM AUTHOR]

Copyright of Fudan University Journal of Medical Sciences is the property of Fudan University Journal of Medical Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arid Zone Research / Ganhanqu Yanjiu is the property of Arid Zone Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Study on Optical Communications / Guangtongxin Yanjiu is the property of Study on Optical Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: At present, tendon-to-bone healing after anterior cruciate ligament (ACL) reconstruction is still the key factor affecting tendon and bone healing. There have been relevant basic research and clinical research reports; however, there is still a lack of relevant reviews. OBJECTIVE: To summarize the microanatomical structure, mechanical and distribution characteristics of related biological factors of tendon-bone enthesis of the ACL and to discuss the research progress in tendon-to-bone healing after ACL reconstruction. METHODS: We searched PubMed, Embase, and Medline databases for relevant literature published within 10 years using the keywords, including “ACL, tendon-to-bone healing, ligament reconstruction,” and matched Mesh terms. We therefore reviewed the structural characteristics of the tendon-bone enthesis of the ACL and summarized the current research progress in clinical tendon-to-bone healing. RESULTS AND CONCLUSION: Studies have shown that the femoral and humeral entheses of the ACL are direct entheses, transitioning from fibrocartilage to osseous tissue. The fibrocartilage layer is thicker on the femoral side than on the tibial side and larger on the anterior medial bundle, which is related to the mechanical stimulation during development. In addition, there is a certain law for the transition of molecules and proteins from tendonous structure to osseous tissue, which is mainly present with type I collagen in the tendon, type II collagen at the attachment point, and then type I collagen in bone tissue. Currently, tendon-to-bone healing is mainly enhanced by biological factors such as platelet-rich plasma. The surgical method and the graft fixation method have been developed to promote tendon-to-bone healing by modifying the mechanical environment or using tissue engineering. However, the results are still somewhat different. By studying the basic level of native ACL enthesis, the surgical reconstruction method can be improved accordingly in order to restore its original healing and mechanical function. In clinical research, studies on the use of biological factors, surgical improvements, and the introduction of new materials have gradually increased, but there is still a lack of relatively systematic verification. In the future, it should be further verified from molecular, protein, cell, and animal experiments to clinical randomized controlled trials. [ABSTRACT FROM AUTHOR]

To investigate the protective effect of cordycepin on vascular endothelial injury in rats with chronic kidney disease (CKD) and its mechanism. Chronic kidney disease rats (n=48) were randomly equally divided into four groups-model group, cordycepin high-dose group, cordycepin middle-dose group, cordycepin low-dose group. The cordycepin high-dose group, cordycepin middle-dose group, cordycepin low-dose group were given 160 mg/kg, 80 mg/kg, 40 mg/kg cordycepin, and the model group were given the same amount of normal saline, once a day for 2 weeks. The 24 h urine output, blood urea nitrogen (BUN) and serum creatinine (Scr) levels of cordycepin high-dose group, cordycepin middle-dose group and cordycepin low-dose group at 1 week and 2 weeks of treatment were all lower than the model group (P<0.05), and the body weight were higher than the model group (P<0.05). The difference compared among the different dose groups were also statistically significant(P<0.05). The relative expression levels of connective tissue growth factor (CTGF) and vascular endothelial growth factor (VEGF) proteins in the high-dose cordycepin group, the middle- dose cordycepin group, and the low-dose cordycepin group at 2 weeks of treatment were higher than the model group (P<0.05), the glomerular sclerosis index and renal tubular injury score were lower than the model group (P<0.05), and the difference compared among different dose groups were also statistically significant (P<0.05). The application of cordycepin in rats with chronic kidney disease can exert protective effect on vascular endothelial damage, promote the improvement of the renal function of rats, and increase the weight of rats, and it is dose-dependent. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nonferrous Metals (Mining Section) is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The titanium alloy samples with different designed hydrogen content were prepared by electrochemical method. The samples with different H contents were examined by X ray diffraction(XRD) and the changes including structure and distribution were analyzed. Including low speed tension，200 h loading and incremental step loading methods were applied for the sensitivity of hydrogen embrittlement of TC4 alloys. Beside of qualitative conclusion on hydrogen embrittlement can be correctly provide，the threshold of loading could be preciously offered using incremental step loading method for hydrogen embrittlement. [ABSTRACT FROM AUTHOR]

Copyright of West China Journal of Stomatology is the property of Sichuan University, West China College of Stomatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[ Objective] The present paper aimed to reasonably use local agricultural climate resources and scientifically carry out maize planting. [ Method] According to climate data (1961 -2017) of 124 meteorological stations and long-term records (1981 - 2017) of maize phenology from 15 agricultural stations of Sichuan, the temporal and spatial distribution of light resources, temperature resources and precipitation during key maize phenological stages were analyzed in Sichuan Province. [Result] The total radiation during the whole growing period and different growth stages of maize both showed decreased trends. The higher radiation resources distributed to the southwestern of the basin and the southern of the Panxi agricultural area. The heat resources during maize growth period showed an increasing trend. Diurnal temperature range of Panxi agricultural area is obviously higher than the basin area. The reference evapotranspiration during each maize growth stages decreased. Water resources shortage occurred in most Panxi agricultural area and the old arid areas in the basin. [ Conclusion ] All regions should make rational use of light, temperature and water resources to provide scientific basis for relevant departments to formulate agricultural production measures and ensure the development of high yield and high quality of corn. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Contemporary Pediatrics is the property of Xiangya Medical Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the correlation between the changes of major atmospheric pollutants, meteorological factors in Shihezi city and the number of hospitalized children with pneumonia. Methods The data of hospitalizations of children with pneumonia in two grade III A hospitals in Shihezi city were collected from January 1, 2015 to December 31, 2017. Pearson and Spearman were used to investigate the impact of major atmospheric pollutants and meteorological factors on the number of hospitalized children with pneumonia through analyzing the data of major atmospheric pollutants and meteorological factors in the same period. Results In the past 3 years, the particulate matter 2. 5 (PM2. 5) , sulfur dioxide(S02) and nitrogen dioxide(N02) showed cyclical and seasonal changes obviously in Shihezi city. The monthly average concentration of PM, 5 and NO2, in winter were signifi cantly higher than the National annual mean level II standard for ambient air quality, excepted SO2, . Besides the average tempera ture, there were positive correlations between the atmospheric pollutants and meteorological factors (P < 0. 05) . The atmospheric pollutants were positively correlated with the number of hospitalized children with pneumonia in the city (P < O. 05) , among which, the impact of NO2, ranked number one, followed by PM2.5, and SO2, ranked last. Effects of atmospheric pollutions on the number of boys with pneumonia were significantly higher than those on girls. The meteorological factors, especially the temperature, had the grea test influence on the number of hospitalized children, which had a significant negative correlation(P< O. 05) . Conclusions There are obvious correlations between atmospheric pollutions and meteorological factors in Shihezi city. They all affect the number of hospitalized children with pneumonia in varying degrees, and the impact on boys are greater than those on girls. Therefore, it is necessary to strengthen control atmospheric pollutions to reduce the number of hospitalized children with pneumonia. [ABSTRACT FROM AUTHOR]