Search

Your search keyword '"Bhattacharya, Dhruva"' showing total 28 results
Start Over Author "Bhattacharya, Dhruva"
28 results on '"Bhattacharya, Dhruva"'

8. Degradation of polycyclic aromatic hydrocarbons by a newly discovered enteric bacterium, leclercia adecarboxylata

Author

Sarma, Priyangshu Manab, Bhattacharya, Dhruva, Krishnan, S., and Lal, Banwari

Subjects
Microbiology -- Research, Enterobacter -- Research, Enterobacter -- Risk factors, Enterobacteriaceae -- Research, Enterobacteriaceae -- Risk factors, Polycyclic aromatic hydrocarbons -- Research, Biological sciences
Abstract

A bacterial strain, PS4040, capable of degrading polycyclic aromatic hydrocarbons for use as the sole carbon source is separated from oily-sludge-contaminated soil. Comparative molecular typing with the clinical strain of L. adecarboxylata indicates that there are few comigrating and few distinct amplimers among them.

Published
2004

9. Evaluation of genetic diversity among Pseudomonas citronellolis strains isolated from oily sludge-contaminated sites

Author

Bhattacharya, Dhruva, Sarma, Priyangshu M., Krishnan, S., Mishra, Sanjeet, and Lal, Banwari

Subjects
Biological diversity -- Genetic aspects, Pseudomonas -- Genetic aspects, Genotype -- Analysis, Polymerase chain reaction -- Usage, Biological sciences
Abstract

The intraspecific diversity among Pseudomonas citronellolis strains is examined using repetitive extragenic palindromes-PCR fingerprinting and PCR-based ribotyping methods. Results indicate that 29 P. citronellolis strains can be put into 12 separate genotypic groups by the former and seven genomic patterns by the latter method. The genetic diversity among the strains is due to different geoclimatic isolation sites, oily sludge type, and chronology of contamination sites.

Published
2003

25. Assessment of intra-species diversity among strains of Acinetobacterbaumannii isolated from sites contaminated with petroleum hydrocarbons.

Author

Sarma, Priyangshu Manab, Bhattacharya, Dhruva, Krishnan, S., and Lal, Banwari

Subjects
*ACINETOBACTER, *HYDROCARBONS, *PETROLEUM, *GENES, *DNA, *GENETICS
Abstract

A total of 96 crude oil - degrading bacterial strains were isolated from 5 geographically diverse sites in India that were contaminated with different types of petroleum hydrocarbons. The strains were identified by sequencing the genes that encode for 16S rRNA. Out of the 96 isolates, 25 strains were identified as Acinetobacter baumannii and selected for the study. All of the selected strains could degrade the total petroleum hydrocarbon fractions of crude oil. These 25 strains were biochemically profiled and grouped into 8 phenovars on the basis of multivariate analysis of their substrate utilization profiles. PCR-based DNA fingerprinting was performed using intergenic repetitive DNA sequences, which divided the selected 25 strains into 7 specific genomic clusters. tRNA intergenic spacer length polymorphism was performed to determine the intra-species relatedness among these 25 strains. It delineated the strains into 8 genomic groups. The present study detected specific variants among the A. baumannii strains with differential degradation capacities for different fractions of crude oil. This could play a significant role in in situ bioremediation. The study also revealed the impact of environmental factors that cause intra-species diversity within the selected strains of A. baumannii. [ABSTRACT FROM AUTHOR]

Published
2004
Full Text
View/download PDF

26. Coding and Noncoding Genomic Regions of Entamoeba histolyticaHave Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies

Author

Bhattacharya, Dhruva, Haque, Rashidul, and Singh, Upinder

Abstract

ABSTRACTTo evaluate genetic variability among Entamoeba histolyticastrains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified.

Published
2005
Full Text
View/download PDF

27. Comparative Genomic Hybridizations of EntamoebaStrains Reveal Unique Genetic Fingerprints That Correlate with Virulence

Author

Shah, Preetam H., MacFarlane, Ryan C., Bhattacharya, Dhruva, Matese, John C., Demeter, Janos, Stroup, Suzanne E., and Singh, Upinder

Abstract

ABSTRACTVariable phenotypes have been identified for Entamoebaspecies. Entamoeba histolyticais invasive and causes colitis and liver abscesses but only in ~10% of infected individuals; 90% remain asymptomatically colonized. Entamoeba dispar, a closely related species, is avirulent. To determine the extent of genetic diversity among Entamoebaisolates and potential genotype-phenotype correlations, we have developed an E. histolyticagenomic DNA microarray and used it to genotype strains of E. histolyticaand E. dispar. On the basis of the identification of divergent genetic loci, all strains had unique genetic fingerprints. Comparison of divergent genetic regions allowed us to distinguish between E. histolyticaand E. dispar, identify novel genetic regions usable for strain and species typing, and identify a number of genes restricted to virulent strains. Among the four E. histolyticastrains, a strain with attenuated virulence was the most divergent and phylogenetically distinct strain, raising the intriguing possibility that genetic subtypes of E. histolyticamay be partially responsible for the observed variability in clinical outcomes. This microarray-based genotyping assay can readily be applied to the study of E. histolyticaclinical isolates to determine genetic diversity and potential genotypic-phenotypic associations.

Published
2005
Full Text
View/download PDF

28. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation.

Author

Eliseo F. Castillo, Dekonenko, Alexander, Arko-Mensah, John, Mandell, Michael A., Dupont, Nicolas, Jiang, Shanya, Delgado-Vargas, Monica, Timmins, Graham S., Bhattacharya, Dhruva, Hongliang Yang, Hutt, Julie, Lyons, C. Rick, Dobos, Karen M., and Deretic, Vojo

Subjects
AUTOPHAGY, MYCOBACTERIUM tuberculosis, INFLAMMATION, MACROPHAGES, CYTOKINES
Abstract

The article discusses the role of autophagy against active tuberculosis. Study shows that autophagy protects against Mycobacterium tuberculosis (M. tuberculosis) infection and excessive inflammation in vivo. It states that macrophages defective for autophagy secrete proinflammatory cytokines and in a cell-autonomous fashion.

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results