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The article references the paper published by the journal in 2015 on the association between day of admission and mortality, which health secretary Jeremy Hunt apparently used in his House of Commons speech on July 16, 2015, claiming that 6,000 people die yearly because of lack of a proper seven day service in hospitals. Topics discussed include where the 6,000 figure came from, whether the Department of Health (DH) commissioned the new analysis, and whether data were shared with the DH.

The author presents the 20 outstanding medicine-related articles that were published in the magazine since the mid-1990s. Topics covered include a research on euthanasia in a 2003 issue, the effect of corruption on the doctor-patient relationship in India in a 2014 issue, and the case against the measles, mumps and rubella vaccine in a 2011 issue.

A personal narrative is presented which explores the author's experience of being nearly duped into authoring an alleged fake research paper focused on procedures for increasing bone mass, structure and strength through intraosseous interventions.

The article announces the finalists for the 2015 UK Research Paper of the Year award which include the "Discrepancies in Autologous Bone Marrow Stem Cell Trials" by A. Nowbar and colleagues published in the "British Medical Journal," "Individualised Pelvic Floor Muscle Training in Women with Pelvic Organ Prolapse" by S. Hagen and colleagues published in the "Lancet," and "The Emerging Risk Factors Collaboration. Glycated Haemoglobin Measurement and Prediction of Cardiovascular Disease" published in the "Journal of the American Medical Association."

The article reports that two research papers that focused on the beneficial effects of the blood pressure drug ramipril in patients with intermittent claudication resulting from peripheral artery disease were retracted after it was discovered that data were fabricated.

The authors discusses a study which explored the link between discrepancies and retractions in clinical trial reports. They explain that the researchers make the conclusion that discrepancies or errors could be an indication of unreliability in clinical trials. They further assert that the researchers perform a case-control study and make generalizations based on sensitivity and specificity. The authors argue that while the link may be real, its practical application is unlikely.

The article reports on the decision by publisher BioMed Central to retract papers in 2015 due to inappropriately influenced peer-review process.

The article discusses the results of an observational study aimed at determining how the representation of women among first authors of original research published in high impact general medical journals changed from 1994 to 2014 and whether it differs between journals. A commentary emphasizing the need to prioritize parity of authorship for journals, universities, and funding agencies is also presented.

A letter to the editor is presented in response to an article in the October 24, 2015 issue on British Secretary of State for Health Jeremy Hunt and data misinterpretation in scientific papers.

The article announces the nominees to the UK Research Paper of the Year of the 2016 "British Medical Journal" Awards which include oxygen saturation targets in infants with bronchiolitis, spironolactone for drug resistant hypertension, and aromatase inhibitors use in early breast cancer.

The article examines the resistance of the American Academy of Child and Adolescent Psychiatry (AACAP) to call for retraction of a paper written by psychiatrist Martin Keller on the Study 329 placebo-controlled, randomized controlled trial of paroxetine and imipramine for adolescents with depression. It discusses the differences between Keller's paper and a restoring invisible and abandoned trials (RIAT) republication, the ethical problems within the profession, and fairness in journalism.

The article discusses the media's position with regards to the new National Health Service (NHS) contract for junior doctors in England. Topics covered include the junior doctors' strike that started on May 3, 2016, periodicals that showed support for the junior doctors including "Mirror," "New Day," and "Guardian," and the differing views of the broadcast media and the print media. It also discusses how the conflicting media coverage affect the public's understanding of the new NHS contract.