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15 results on '"Rui Zhang"'

1. Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents

Author

Shanna Yang, Kimberly Herman, Sophie K. Elvig, Peter Manza, Helene Benveniste, Nora D. Volkow, Danielle S. Kroll, Jan Willem van der Veen, Nancy Diazgranados, Janaina C. M. Vendruscolo, Melanie L. Schwandt, Anders Fink-Jensen, Dana E. Feldman, Mackenzie C. Cervenka, Dardo Tomasi, Katherine L. McPherson, Ehsan Shokri-Kojori, Leandro F. Vendruscolo, George F. Koob, Catherine L. Biesecker, Gene-Jack Wang, Corinde E. Wiers, Rui Zhang, and Sara A. Turner

Subjects
medicine.medical_specialty, medicine.medical_treatment, Alcohol, Alcohol use disorder, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Detoxification, mental disorders, medicine, Anterior cingulate cortex, Research Articles, 030304 developmental biology, 0303 health sciences, Multidisciplinary, business.industry, Alcohol dependence, Glutamate receptor, Neurotoxicity, SciAdv r-articles, medicine.disease, medicine.anatomical_structure, Endocrinology, chemistry, business, 030217 neurology & neurosurgery, Ketogenic diet, Research Article, Neuroscience
Abstract

A ketogenic diet lowered benzodiazepine use during withdrawal in patients with AUD and blunted alcohol administration in rats., Individuals with alcohol use disorder (AUD) show elevated brain metabolism of acetate at the expense of glucose. We hypothesized that a shift in energy substrates during withdrawal may contribute to withdrawal severity and neurotoxicity in AUD and that a ketogenic diet (KD) may mitigate these effects. We found that inpatients with AUD randomized to receive KD (n = 19) required fewer benzodiazepines during the first week of detoxification, in comparison to those receiving a standard American (SA) diet (n = 14). Over a 3-week treatment, KD compared to SA showed lower “wanting” and increased dorsal anterior cingulate cortex (dACC) reactivity to alcohol cues and altered dACC bioenergetics (i.e., elevated ketones and glutamate and lower neuroinflammatory markers). In a rat model of alcohol dependence, a history of KD reduced alcohol consumption. We provide clinical and preclinical evidence for beneficial effects of KD on managing alcohol withdrawal and on reducing alcohol drinking.

Published
2021

2. Logic operations with active topological defects.

Author

Rui Zhang, Mozaffari, Ali, and de Pablo, Juan J.

Subjects
*LYOTROPIC liquid crystals, *NEMATIC liquid crystals, *LATTICE Boltzmann methods, *LOGIC, *CHEMICAL templates
Abstract

The article offers information about the logic operations performed by semiconductor-based transistors are the basis of modern computing. It mentions about the concept of using topological defects in active matter to perform logic operations. It discusses the potential to perform computations and transmit information in active soft materials.

Published
2022
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3. An ion redistributor for dendrite-free lithium metal anodes

Author

Rui Zhang, Xue-Qiang Zhang, Xin-Bing Cheng, Xiang Chen, Qiang Zhang, Chen-Zi Zhao, Peng-Yu Chen, and Bo-Quan Li

Subjects
Materials science, Separator (oil production), chemistry.chemical_element, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Ion, Metal, Dendrite (crystal), Electrochemistry, Research Articles, Multidisciplinary, SciAdv r-articles, 021001 nanoscience & nanotechnology, Alkali metal, 0104 chemical sciences, Anode, Chemical engineering, chemistry, visual_art, Physical Sciences, visual_art.visual_art_medium, Lithium, 0210 nano-technology, Faraday efficiency, Research Article
Abstract

Dendrite-free lithium metal anodes are achieved by solid lithium ionic conductors as ion redistributors to homogenize Li ions., Lithium (Li) metal anodes have attracted considerable interest due to their ultrahigh theoretical gravimetric capacity and very low redox potential. However, the issues of nonuniform lithium deposits (dendritic Li) during cycling are hindering the practical applications of Li metal batteries. Herein, we propose a concept of ion redistributors to eliminate dendrites by redistributing Li ions with Al-doped Li6.75La3Zr1.75Ta0.25O12 (LLZTO) coated polypropylene (PP) separators. The LLZTO with three-dimensional ion channels can act as a redistributor to regulate the movement of Li ions, delivering a uniform Li ion distribution for dendrite-free Li deposition. The standard deviation of ion concentration beneath the LLZTO composite separator is 13 times less than that beneath the routine PP separator. A Coulombic efficiency larger than 98% over 450 cycles is achieved in a Li | Cu cell with the LLZTO-coated separator. This approach enables a high specific capacity of 140 mAh g−1 for LiFePO4 | Li pouch cells and prolonged cycle life span of 800 hours for Li | Li pouch cells, respectively. This strategy is facile and efficient in regulating Li-ion deposition by separator modifications and is a universal method to protect alkali metal anodes in rechargeable batteries.

Published
2018

4. Isolation of the simplest hydrated acid

Author

Michihisa Murata, Takeshi Hasegawa, Takafumi Shimoaka, Atsushi Wakamiya, Yasujiro Murata, and Rui Zhang

Subjects
Diffraction, Materials science, Fullerene, water, 010402 general chemistry, 01 natural sciences, Dissociation (chemistry), chemistry.chemical_compound, Molecule, single crystal x-ray analysis, Research Articles, hydrogen fluoride, Multidisciplinary, 010405 organic chemistry, Hydrogen bond, fullerene, Solvation, SciAdv r-articles, Hydrogen fluoride, NMR, 0104 chemical sciences, Chemistry, chemistry, Chemical physics, open-cage fullerene, molecular surgery, encapsulation, Single crystal, hydration, Research Article
Abstract

The simplest hydrated HF was realized, whose properties were revealed by x-ray analysis, spectroscopy, and theoretical studies., Dissociation of an acid molecule in aqueous media is one of the most fundamental solvation processes but its details remain poorly understood at the distinct molecular level. Conducting high-pressure treatments of an open-cage fullerene C70 derivative with hydrogen fluoride (HF) in the presence of H2O, we achieved an unprecedented encapsulation of H2O·HF and H2O. Restoration of the opening yielded the endohedral C70s, that is, (H2O·HF)@C70, H2O@C70, and HF@C70 in macroscopic scales. Putting an H2O·HF complex into the fullerene cage was a crucial step, and it would proceed by the synergistic effects of “pushing from outside” and “pulling from inside.” The structure of the H2O·HF was unambiguously determined by single crystal x-ray diffraction analysis. The nuclear magnetic resonance measurements revealed the formation of a hydrogen bond between the H2O and HF molecules without proton transfer even at 140°C.

Published
2017

5. Recording brain activities in unshielded Earth's field with optically pumped atomic magnetometers.

Author

Rui Zhang, Wei Xiao, Yudong Ding, Yulong Feng, Xiang Peng, Liang Shen, Chenxi Sun, Teng Wu, Yulong Wu, Yucheng Yang, Zhaoyu Zheng, Xiangzhi Zhang, Jingbiao Chen, and Hong Guo

Subjects
*DRUG infusion pumps, *ALPHA rhythm, *MAGNETOMETERS, *MAGNETIC field measurements, *SUPERCONDUCTING quantum interference devices, *BIOMAGNETISM, *BRAIN
Abstract

The article explores the understanding the relationship between brain activity and specific mental function as important for medical diagnosis of brain symptoms, such as epilepsy. It discusses about the Magnetoencephalography, which uses an array of highsensitivity magnetometers to record magnetic field signals generated from neural currents occurring naturally in the brain, as a noninvasive method for locating the brain activities.

Published
2020
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6. The carrier transition from Li atoms to Li vacancies in solid-state lithium alloy anodes.

Author

Yang Lu, Chen-Zi Zhao, Rui Zhang, Hong Yuan, Li-Peng Hou, Zhong-Heng Fu, Xiang Chen, Jia-Qi Huang, and Qiang Zhang

Abstract

The article discusses the crucial aspect of lithium (Li) kinetics in solid-state batteries. It explores the kinetic transition from alloying reactions to metal deposition in Li alloy anodes and identifies the carrier transition from Li atoms to Li vacancies during the lithiation process. The rate-determining step in the lithiation processes is determined to be charge transfer or Li atom diffusion, shedding light on the fundamental processes governing stable cycling in solid-state batteries.

Published
2021
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7. Bio-coal: A renewable and massively producible fuel from lignocellulosic biomass.

Author

Bin-Hai Cheng, Bao-Cheng Huang, Rui Zhang, Ya-Li Chen, Shun-Feng Jiang, Yan Lu, Xue-Song Zhang, Hong Jiang, and Han-Qing Yu

Subjects
*THERMAL coal, *WHEAT straw, *BITUMINOUS coal, *BIOMASS, *FUEL, *INDUCTIVELY coupled plasma mass spectrometry
Abstract

The article offers information related to the Bio-coal fuel, a renewable and massively producible fuel from lignocellulosic biomass. It mentions that development of renewable energy is essential to mitigating the fossil fuel shortage and climate change issues. It also mentions that excessive exploitation and consumption of fossil fuel will not only gradually exhaust its storage in the earth but also cause severe climate change and environment pollution problems.

Published
2020
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8. Design of Ru-Ni diatomic sites for efficient alkaline hydrogen oxidation.

Author

Lili Han, Pengfei Ou, Wei Liu, Xiang Wang, Hsiao-Tsu Wang, Rui Zhang, Chih-Wen Pao, Xijun Liu, Way-Faung Pong, Jun Song, Zhongbin Zhuang, Mirkin, Michael V., Jun Luo, and Xin, Huolin L.

Subjects
*HYDROGEN evolution reactions, *OXYGEN reduction, *HYDROGEN oxidation, *MATERIALS science, *X-ray absorption near edge structure, *ION-permeable membranes, *INDUCTIVELY coupled plasma mass spectrometry
Abstract

The article offers information related to the Design of Ru-Ni diatomic sites for efficient alkaline hydrogen oxidation. It discusses the establishment of HOR catalytic activities of single-atom and diatomic sites as a function of H and OH binding energies to screen the optimal active sites for the HOR. As a result, the Ru-Ni diatomic is identified as the best active center.

Published
2022
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9. Cryo-EM structure and electrophysiological characterization of ALMT from Glycine max reveal a previously uncharacterized class of anion channels.

Author

Li Qin, Ling-hui Tang, Jia-shu Xu, Xian-hui Zhang, Yun Zhu, Chun-rui Zhang, Mei-hua Wang, Xue-lei Liu, Fei Li, Fei Sun, Min Su, Yujia Zhai, and Yu-hang Chen

Subjects
*SOYBEAN, *CHLORIDE channels, *ION channels, *ANIONS, *BRACHYPODIUM, *ELECTROPHYSIOLOGY, *GREEN fluorescent protein, *RYANODINE receptors
Abstract

The article offers information on the Aluminum-activated malate transporters (ALMTs) form an anion channel family that plays essential roles in diverse functions in plants. It discusses that the molecular basis of ALMT12/QUAC1 activity remains elusive. Here, we describe the cryo-EM structure of ALMT12/QUAC1 from Glycine max at 3.5-Å resolution; and mentions that The transmembrane and cytoplasmic domains are assembled into a twisted two-layer architecture.

Published
2022
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11. Correcting a major error in assessing organic carbon pollution in natural waters.

Author

Nianzhi Jiao, Jihua Liu, Edwards, Bethanie, Zongqing Lv, Ruanhong Cai, Yongqin Liu, Xilin Xiao, Jianning Wang, Fanglue Jiao, Rui Wang, Xingyu Huang, Bixi Guo, Jia Sun, Rui Zhang, Yao Zhang, Kai Tang, Qiang Zheng, Farooq Azam, John Batt, and Wei-Jun Cai

Subjects
*WATER pollution, *BP Deepwater Horizon Explosion & Oil Spill, 2010, *DISSOLVED oxygen in water, *LIFE sciences, *EARTH sciences, *ATMOSPHERIC sciences, *ENVIRONMENTAL sciences
Published
2021
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12. Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents.

Author

Wiers, Corinde E., Vendruscolo, Leandro F., van der Veen, Jan-Willem, Manza, Peter, Shokri-Kojori, Ehsan, Kroll, Danielle S., Feldman, Dana E., McPherson, Katherine L., Biesecker, Catherine L., Rui Zhang, Herman, Kimberly, Elvig, Sophie K., Vendruscolo, Janaina C. M., Turner, Sara A., Shanna Yang, Schwandt, Melanie, Tomasi, Dardo, Cervenka, Mackenzie C., Fink-Jensen, Anders, and Benveniste, Helene

Subjects
*OPERANT behavior, *ALCOHOL, *ALCOHOL withdrawal syndrome, *REDUCING diets, *KETOGENIC diet
Abstract

The article presents a study of the beneficial effects of ketogenic diet (KD) on alcohol withdrawal symptoms in humans and alcohol intake in rodents. Topics discussed include the mortality rate and the physiological consequences of alcohol use disorder (AUD), the emphasis of the study on the dorsal anterior cingulate cortex (dACC) for functional magnetic resonance imaging (fMRI) and MRI, and ability of KD to reduce neuroinflammation.

Published
2021
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13. Ionizable lipid nanoparticles for in utero mRNA delivery.

Author

Riley, Rachel S., Kashyap, Meghana V., Billingsley, Margaret M., White, Brandon, Alameh, Mohamad-Gabriel, Bose, Sourav K., Zoltick, Philip W., Hiaying Li, Rui Zhang, Cheng, Andrew Y., Weissman, Drew, Peranteau, William H., and Mitchell, Michael J.

Subjects
*FETOFETAL transfusion, *CATIONIC lipids, *MESSENGER RNA, *PEPTIDE nucleic acids, *LIPIDS, *CORD blood transplantation
Abstract

The article offers information about the ionizable lipid nanoparticles for in utero mRNA delivery. It mentions about the clinical advances that enable the prenatal diagnosis of genetic diseases that are candidates for gene and enzyme therapies such as messenger RNA (mRNA)–mediated protein replacement.

Published
2021
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14. Prolate and oblate chiral liquid crystal spheroids.

Author

Sadati, Monirosadat, Martinez-Gonzalez, Jose A., Ye Zhou, Qazvini, Nader Taheri, Khia Kurtenbach, Xiao Li, Bukusoglu, Emre, Rui Zhang, Abbott, Nicholas L., Hernandez-Ortiz, Juan Pablo, and de Pablo, Juan J.

Subjects
*CHOLESTERIC liquid crystals, *LIQUID crystals, *SPHEROIDAL state, *MESOPHASES, *MATERIALS science, *LIQUID crystal states, *NEMATIC liquid crystals, *MOLECULAR shapes
Abstract

The article focuses on chiral materials and examines the palette of morphologies that arises when micro droplets are deformed into non-spherical shapes in a controllable manner. It discusses the use of geometrical confinement and mechanical strain to manipulate orientational order, phase transitions, and topological defects that arise in chiral liquid crystal droplets.

Published
2020
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15. Structured silicon for revealing transient and integrated signal transductions in microbial systems.

Author

Xiang Gao, Yuanwen Jiang, Yiliang Lin, Kyoung-Ho Kim, Yin Fang, Jaeseok Yi, Lingyuan Meng, Hoo-Cheol Lee, Zhiyue Lu, Owen Leddy, Rui Zhang, Qing Tu, Wei Feng, Nair, Vishnu, Griffin, Philip J., Fengyuan Shi, Shekhawat, Gajendra S., Dinner, Aaron R., Hong-Gyu Park, and Bozhi Tian

Subjects
*CELLULAR signal transduction, *QUORUM sensing, *MATERIALS science, *POISSON'S ratio, *MECHANICAL shock, *HIGH power lasers, *SEMICONDUCTOR nanowires, *NANOWIRES
Abstract

The article presents a research on use of structured silicon for revealing transient and integrated signal transductions in microbial systems. Topics discussed include bacterial response to transient physical stress is critical to their homeostasis and survival in the dynamic natural environment; and lack of biophysical tools capable of delivering precise and localized physical perturbations to a bacterial community.

Published
2020
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