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Researchers at Guangzhou University of Chinese Medicine conducted a study to explore the causal relationship between ischemic stroke and epilepsy, specifically generalized epilepsy. Using Mendelian randomization analysis, they found a causal link between ischemic stroke and the risk of generalized epilepsy, but not focal epilepsy. The study also identified diastolic blood pressure and BMI as factors with a causal relationship to epilepsy risk. This research provides genetic evidence that can help stratify the risk of post-stroke epilepsy. [Extracted from the article]

A recent study conducted at Mayo Clinic in Rochester, Minnesota has found that centromedian thalamic deep brain stimulation (CM-DBS) may be an effective treatment option for individuals with drug-resistant idiopathic generalized epilepsy (IGE). The study analyzed the targeting and efficacy of CM-DBS in five patients with drug-resistant IGE and found that the stimulation of the middle ventral CM nucleus resulted in the best outcomes. The researchers also discovered that the connectivity strength between the sweet-spot region and central peri-Rolandic cortex was significantly increased. These findings suggest that CM-DBS can be an effective treatment for patients with IGE and emphasize the importance of accurate targeting and analysis. [Extracted from the article]

A recent report from the University of Oslo in Norway explores the genetic overlap between common epilepsies and psychiatric disorders. The researchers aimed to identify shared genetic loci between these conditions to gain a better understanding of their comorbidity and shared clinical features. Through their analysis, they identified 40 distinct loci associated with both epilepsies and psychiatric disorders, with the majority of epilepsy risk loci being shared with schizophrenia. The findings suggest a complex genetic relationship between these disorders and indicate that overlapping genetic risk may contribute to shared pathophysiological and clinical features. [Extracted from the article]

A systematic review conducted by researchers at the University of Campinas in Brazil explores the occurrence of déjà vu (DV) in individuals with idiopathic generalized epilepsies (IGEs). DV, a sensation of familiarity in the present moment, has traditionally been associated with focal seizures originating from the medial temporal lobe. However, this study found that DV can also occur in IGEs, although at a lower frequency compared to temporal lobe epilepsy (TLE). The researchers emphasize the importance of recognizing these auras in order to avoid misdiagnosing IGE as focal epilepsy and making incorrect treatment decisions. [Extracted from the article]

A recent study from New York University (NYU) highlights the misunderstandings, challenges, and opportunities surrounding idiopathic generalized epilepsy (IGE). The research reveals that IGE is often misdiagnosed as focal epilepsy, leading to underdiagnosis. It also emphasizes the need for improved diagnostic sensitivity and specificity, as well as better scientific understanding and therapies for IGE. The study concludes that IGE is an understudied condition with inadequate diagnostic and treatment options. [Extracted from the article]

A study conducted by researchers at Guangzhou Medical University in China has identified a potential genetic cause for generalized epilepsy. The study focused on the USP25 gene, which encodes a protein involved in neural fate determination. Through whole exome sequencing, the researchers identified five variants in the USP25 gene in eight individuals affected by generalized seizures and/or febrile seizures. Functional tests in mice and in vitro experiments provided evidence that these variants can cause a form of generalized epilepsy with dominant inheritance. This research highlights the significance of USP25 heterozygous variants in epilepsy and emphasizes the critical role of USP25 in the brain. [Extracted from the article]

A study conducted at the University of Melbourne in Australia evaluated the effectiveness of huperzine A in treating genetic generalized epilepsy (GGE) with absence seizures. The study found that huperzine A significantly reduced seizures in the 30-minute and 60-minute intervals after treatment, as well as during the cumulative 24-hour post-treatment period. The duration of action of huperzine A was shorter compared to ethosuximide, a positive control drug. The study suggests that huperzine A shows promise for clinical efficacy in GGE. [Extracted from the article]

A recent study conducted by the University of Indonesia has developed and validated a questionnaire called the Indonesian Pediatric Epilepsy Questionnaire (INA-PEPSI) to diagnose epilepsy and distinguish between focal and generalized epilepsy in infants and children in Indonesia. The questionnaire was administered to 75 children aged 1 month to 18 years old who had experienced unprovoked seizures. The questionnaire demonstrated good diagnostic performance, with high sensitivity and specificity in diagnosing epilepsy and distinguishing between epilepsy types. The study highlights the potential of the INA-PEPSI questionnaire to aid in the diagnosis of epilepsy in resource-limited settings where advanced diagnostic tools and specialists are scarce. However, further validation studies are needed to confirm these findings. [Extracted from the article]

A research report from Gheorghe Asachi Technical University in Iasi, Romania discusses the development of a novel approach for classifying patients with focal and generalized epilepsy based on the analysis of EEG signals. The researchers used the Ensemble Empirical Mode Decomposition (EEMD) and Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) techniques to extract features from the EEG signals. They then employed the K-nearest neighbors (KNN) and Naïve Bayes (NB) classifiers to accurately classify the signals into focal and generalized categories. The combination of the CEEMDAN-based approach and KNN classifier achieved a classification rate of 94.54%. The researchers aim to contribute to the development of effective and efficient diagnostic systems for epilepsy. [Extracted from the article]

A recent report from the University of Catania in Italy discusses new findings on generalized epilepsy. The research focuses on the SRY-box transcription factor (SOX) gene family, which plays a role in the development and neurogenesis of the nervous system. Through whole exome sequencing, a de novo variation was discovered in the SOX12 gene in a patient with generalized epilepsy, intellectual disability, and childhood emotional behavioral disorders. This variant is located in a critical functional site of the SOX12 protein and is predicted to have deleterious effects on protein structure. The study aims to establish a correlation between the SOX12 gene and the patient's symptoms. [Extracted from the article]

A recent study conducted by researchers at Jilin University in China explored the relationship between ischemic stroke (IS) and epilepsy. Using genetic data from the Genome-Wide Association Study (GWAS) database, the researchers found that IS was associated with an increased risk of developing epilepsy, particularly generalized epilepsy. However, no clear causal association was found between epilepsy and the onset of stroke. The study suggests that further investigation is needed to understand the mechanisms behind the effect of epilepsy on the pathogenesis of IS. [Extracted from the article]

A recent study conducted by Guangzhou Medical University in China aimed to explore the genetic causes of idiopathic generalized epilepsies (IGEs). The researchers performed trio-based whole-exome sequencing on 60 cases of IGEs and identified seven candidate genetic variants. One variant in the SLC2A1 gene was determined to be pathogenic, while six other variants were considered causative after evaluation of clinical concordance. The study suggests that GABRB1 may be a novel causative gene for IGE and calls for further research on the topic. [Extracted from the article]

This document provides information about a clinical trial conducted by Biohaven Pharmaceuticals, Inc. The trial, NCT06425159, aims to determine the effectiveness and safety of BHV-7000 in treating adults with idiopathic generalized epilepsy with generalized tonic-clonic seizures. The trial is currently in the interventional phase and is expected to be completed by July 31, 2026. The eligibility criteria include a diagnosis of Idiopathic Generalized Epilepsy, failure of previous treatments, and a history of generalized tonic-clonic seizures. The trial is being conducted in the United States and is regulated by the U.S. FDA. [Extracted from the article]

A preprint abstract discusses the effects of hyperventilation on individuals with idiopathic generalized epilepsy (IGE) compared to healthy controls. The study found that during hyperventilation, both groups experienced similar decreases in cerebral blood flow (CBF) in cortical gray matter and basal ganglia. However, in the thalamus, CBF decreased less in IGE patients compared to controls. Additionally, delta band power in the electroencephalography (EEG) increased more in IGE patients than in controls. The study suggests that there may be differences in the relationship between hyperventilation, EEG band power, and regional CBF in individuals with IGE. [Extracted from the article]

This article discusses an observational study on the structural-functional connectome in patients with epilepsy. The study explores the concept of the brain as a complex network and its impact on the understanding of epilepsy. It highlights the shift from the traditional view of focal epilepsy to the concept of the epileptogenic network, which involves alterations in both the structural and functional networks of the brain. The study aims to identify and remove the epileptogenic network as a potential therapy for drug-resistant focal epilepsies. The article also mentions the development of noninvasive approaches that integrate structural neuroimaging and cortical electrical activity to diagnose and define the epileptogenic network. This document provides information about a research study on the relationship between the structural-functional connectome and cognitive function in patients with epilepsy. The study aims to understand how the brain's connectivity relates to cognitive impairment in epilepsy patients. The study is observational and will involve the reconstruction of EEG and MRI data. The study is currently recruiting participants and is expected to be completed by December 2026. The eligibility criteria include a diagnosis of epilepsy, MRI scans of the brain, and the ability to participate in a neuropsychological assessment. The study is being conducted in Italy. The contact information for the study is provided for those interested in participating. [Extracted from the article]

Researchers from Mugla Sitki Kocman University Faculty of Medicine in Turkey conducted a study to examine medication adherence and prospective memory functions in individuals diagnosed with focal and generalized epilepsy. The study included 51 patients with focal epilepsy and 51 with generalized epilepsy. The researchers found no difference in prospective memory functions and medication adherence between the two groups. However, they did find near-significant correlations between medication adherence and memory function. The researchers concluded that more comprehensive studies are needed to further understand the relationship between memory and medication adherence in epilepsy. [Extracted from the article]

A recent study examined the use of centromedian thalamic deep brain stimulation (CM-DBS) as a potential treatment for drug-resistant idiopathic generalized epilepsy (IGE). The study included five patients with IGE who were treated with CM-DBS. The results showed that CM-DBS can be an effective treatment option for patients with IGE, with a median reduction in seizure frequency of 60%. The study also found that accurate targeting and volumetric analysis of the CM nucleus were important factors in achieving positive outcomes. However, it is important to note that this study has not yet undergone peer review. [Extracted from the article]

A recent study conducted at Sapienza University of Rome investigated the effectiveness of topiramate (TPM) and levetiracetam (LEV) as first-line antiseizure medication in women of childbearing potential with idiopathic generalized epilepsy (IGE). The study found that women treated with TPM had higher risks of treatment failure and withdrawal, and were less likely to achieve seizure freedom at 12 months compared to women treated with LEV. The study suggests that there is a low tendency among clinicians to use TPM in this population, and the available data on effectiveness do not support its use. [Extracted from the article]

A recent study conducted at the Affiliated Hospital of Zunyi Medical University in China explored the changes in the white matter functional network in children with idiopathic generalized epilepsy (IGE). The researchers used resting-state functional magnetic resonance imaging (MRI) and T-weighted images to analyze the topological characteristics of the network. They found that the WM functional network exhibited increased assortativity at the network level and nodal disturbances at the nodal level. These changes were associated with cognitive function and may serve as potential biomarkers for IGE. The study provides valuable insights into the pathogenesis of IGE and suggests the potential clinical utility of the WM functional network in classifying the disease. [Extracted from the article]

A recent study conducted at Jilin Cancer Hospital in Changchun, People's Republic of China, explored the genetic correlations and causality between epilepsy and psychiatric comorbidities, specifically attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). The study identified single-nucleotide polymorphisms associated with epilepsy and seven psychiatric comorbidities from genome-wide association studies. The findings revealed a significant genetic causality between ADHD and generalized epilepsy, as well as between focal epilepsy and OCD. However, the study emphasized the need for further research to definitively clarify these genetic causal associations. [Extracted from the article]

A recent study conducted by researchers from the University of Virginia explores the relationship between Alzheimer's disease (AD) and epilepsy. The study used a method called Mendelian randomization to analyze genetic predisposition to AD, cerebrospinal fluid biomarkers of AD, and various types of epilepsy. The findings suggest a causal link between AD, amyloid pathology, and generalized epilepsy, as well as a close association between AD and focal hippocampal sclerosis. The researchers recommend further investigation into the screening and clinical implications of seizures in AD. [Extracted from the article]

A recent study conducted by researchers at the University of Electronic Science and Technology of China explores the role of the primary sensorimotor system in generalized epilepsy. The study examines the functional interaction between the cerebellum and cerebrum and reveals altered mapping of cerebral motor components to the cerebellum in patients with idiopathic generalized epilepsy. The findings suggest that the cerebral primary motor system influences the hierarchical architecture of the cerebellum and contributes to motor functional abnormalities in epilepsy patients. This research provides valuable insights into the collaborative processing of sensorimotor information in epilepsy patients. [Extracted from the article]

A recent study conducted by researchers from Fourth Military Medical University in China focused on status epilepticus (SE) in patients with genetic generalized epilepsy (GGE). The study included nine patients with GGE, with the majority being female. The researchers analyzed the demographic and clinical characteristics of the patients, as well as the SE patterns and termination methods. The study found that the seizure type of SE in patients with GGE is often consistent with their major symptoms, and oral midazolam may be an option to terminate SE in these patients. The findings provide valuable insights into the understanding and management of SE in individuals with GGE. [Extracted from the article]

A study conducted at the First Affiliated Hospital of Xi'an Jiaotong University examined the time it took for different epileptic patients to experience their first interictal epileptiform discharges (IEDs) during electroencephalography (EEG) monitoring. The researchers retrospectively analyzed 241 patients with epilepsy who underwent a 24-hour long-term video EEG monitoring procedure. They found that patients with generalized epilepsy had a shorter latency to IEDs compared to those with focal-onset epilepsy. The study also concluded that patients with late-onset epilepsy or without recent episodes may require longer EEG monitoring periods. [Extracted from the article]

A recent study investigated the use of polygenic risk scores (PRSs) as biomarkers for epilepsy risk. The study analyzed the electronic health records of over 360,000 individuals in Finland over a span of up to 50 years. The results showed that individuals with a high genetic generalized epilepsy PRS had an increased risk for genetic generalized epilepsy (GGE) across their lifetime and after unspecified seizure events. The study also found that the effects of PRSs were larger in females and younger age groups. These findings suggest that PRSs could potentially serve as biomarkers for epilepsy diagnosis. However, it is important to note that this study has not yet undergone peer review. [Extracted from the article]

A case report from Liaoning, People's Republic of China, discusses a rare condition called idiopathic generalized epilepsy with phantom absences, absence status, and generalized tonic-clonic seizures. The report describes the case of a 31-year-old woman who presented with a 16-year history of seizures. The patient was diagnosed with idiopathic generalized epilepsy based on electroencephalogram (EEG) findings and was successfully treated with oral sodium valproate. The report concludes that EEG is the key diagnostic method for this condition and that antiepileptic drugs are effective in controlling seizures. [Extracted from the article]

In the overall population, retention rates at 3, 6, and 12 months were 88.0%, 77.6%, and 61.4%, respectively; responder rates at 12 months were 58.5% for total seizures, 54.6% for focal seizures, and 77.7% for generalized seizures, and corresponding seizure freedom rates were 23.6%, 19.0%, and 51.3%, respectively. Keywords: Memphis; State:Tennessee; United States; North and Central America; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Generalized Epilepsy; Health and Medicine; Nervous System Diseases and Conditions; Neurologic Manifestations; Seizures EN Memphis State:Tennessee United States North and Central America Brain Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Generalized Epilepsy Health and Medicine Nervous System Diseases and Conditions Neurologic Manifestations Seizures 665 665 1 11/06/23 20231106 NES 231106 2023 NOV 6 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators discuss new findings in Central Nervous System Diseases and Conditions - Generalized Epilepsy. [Extracted from the article]

Brain Diseases and Conditions, Central Nervous System Agents, Central Nervous System Diseases and Conditions, Drugs and Therapies, Epilepsy, Health and Medicine, Lamotrigine Therapy, Levetiracetam Therapy, Pharmaceuticals, Pyrrolidine Anticonvulsants, Triazine Anticonvulsants, Generalized Epilepsy Keywords: Brain Diseases and Conditions; Central Nervous System Agents; Central Nervous System Diseases and Conditions; Drugs and Therapies; Epilepsy; Generalized Epilepsy; Health and Medicine; Lamotrigine Therapy; Levetiracetam Therapy; Pharmaceuticals; Pyrrolidine Anticonvulsants; Triazine Anticonvulsants EN Brain Diseases and Conditions Central Nervous System Agents Central Nervous System Diseases and Conditions Drugs and Therapies Epilepsy Generalized Epilepsy Health and Medicine Lamotrigine Therapy Levetiracetam Therapy Pharmaceuticals Pyrrolidine Anticonvulsants Triazine Anticonvulsants 1811 1811 1 10/16/23 20231020 NES 231020 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on generalized epilepsy have been published. [Extracted from the article]

Odense, Denmark, Europe, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Drugs and Therapies, Epilepsy, Generalized Epilepsy, Health and Medicine Keywords: Odense; Denmark; Europe; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drugs and Therapies; Epilepsy; Generalized Epilepsy; Health and Medicine EN Odense Denmark Europe Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drugs and Therapies Epilepsy Generalized Epilepsy Health and Medicine 224 224 1 09/19/23 20230923 NES 230923 2023 SEP 18 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on Central Nervous System Diseases and Conditions - Generalized Epilepsy. [Extracted from the article]

Keywords: Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drugs and Therapies; Epilepsy; Generalized Epilepsy; Health and Medicine EN Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drugs and Therapies Epilepsy Generalized Epilepsy Health and Medicine 1064 1064 1 08/14/23 20230818 NES 230818 2023 AUG 18 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on generalized epilepsy are discussed in a new report. Keywords for this news article include: Marmara University, Istanbul, Turkey, Eurasia, Drugs and Therapies, Health and Medicine, Generalized Epilepsy, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions. Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Drugs and Therapies, Epilepsy, Health and Medicine, Generalized Epilepsy. [Extracted from the article]

Keywords for this news article include: Odense, Denmark, Europe, Anxiety, Anxiety Disorders, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Epilepsy, Generalized Epilepsy, Health and Medicine, Mental Health, Mental Health Diseases and Conditions, Psychiatric, Psychiatry, Odense University Hospital. Keywords: Odense; Denmark; Europe; Anxiety; Anxiety Disorders; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Generalized Epilepsy; Health and Medicine; Mental Health; Mental Health Diseases and Conditions; Psychiatric; Psychiatry EN Odense Denmark Europe Anxiety Anxiety Disorders Brain Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Generalized Epilepsy Health and Medicine Mental Health Mental Health Diseases and Conditions Psychiatric Psychiatry 969 969 1 08/14/23 20230818 NES 230818 2023 AUG 18 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators publish new report on Central Nervous System Diseases and Conditions - Generalized Epilepsy. [Extracted from the article]

Keywords: Istanbul; Turkey; Eurasia; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Consciousness Disorders; Diagnostics and Screening; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine; Nervous System Diseases and Conditions; Neurobehavioral Manifestations; Neurologic Diseases and Conditions; Neurologic Manifestations; Pediatrics; Syncope; Unconsciousness EN Istanbul Turkey Eurasia Brain Diseases and Conditions Central Nervous System Diseases and Conditions Consciousness Disorders Diagnostics and Screening Epilepsy Generalized Epilepsy Genetics Health and Medicine Nervous System Diseases and Conditions Neurobehavioral Manifestations Neurologic Diseases and Conditions Neurologic Manifestations Pediatrics Syncope Unconsciousness 532 532 1 08/14/23 20230818 NES 230818 2023 AUG 19 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Central Nervous System Diseases and Conditions - Generalized Epilepsy is the subject of a report. Istanbul, Turkey, Eurasia, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Consciousness Disorders, Diagnostics and Screening, Epilepsy, Genetics, Health and Medicine, Nervous System Diseases and Conditions, Neurobehavioral Manifestations, Neurologic Diseases and Conditions, Neurologic Manifestations, Pediatrics, Syncope, Unconsciousness, Generalized Epilepsy. [Extracted from the article]

Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Epilepsy, Generalized Epilepsy, Genetics, Health and Medicine Keywords: Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine EN Brain Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Generalized Epilepsy Genetics Health and Medicine 1056 1056 1 07/24/23 20230728 NES 230728 2023 JUL 28 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Researchers detail new data in generalized epilepsy. [Extracted from the article]

Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Epilepsy, Genetics, Health and Medicine, Risk and Prevention, Generalized Epilepsy Keywords: Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine; Risk and Prevention EN Brain Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Generalized Epilepsy Genetics Health and Medicine Risk and Prevention 1197 1197 1 07/10/23 20230714 NES 230714 2023 JUL 14 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Research findings on generalized epilepsy are discussed in a new report. [Extracted from the article]

According to the news reporters, the research concluded: "Elucidating the role of the thalamus in generalized epilepsy syndromes may lead to new opportunities to better treat pharmaco-resistant generalized epilepsy by thalamic modulation and dietary therapy." San Francisco, State:California, United States, North and Central America, Brain, Brain Diseases and Conditions, Central Nervous System, Central Nervous System Diseases and Conditions, Diencephalon, Drugs and Therapies, Epilepsy, Generalized Epilepsy, Health and Medicine, Thalamus Keywords: San Francisco; State:California; United States; North and Central America; Brain; Brain Diseases and Conditions; Central Nervous System; Central Nervous System Diseases and Conditions; Diencephalon; Drugs and Therapies; Epilepsy; Generalized Epilepsy; Health and Medicine; Thalamus EN San Francisco State:California United States North and Central America Brain Brain Diseases and Conditions Central Nervous System Central Nervous System Diseases and Conditions Diencephalon Drugs and Therapies Epilepsy Generalized Epilepsy Health and Medicine Thalamus 509 509 1 06/05/23 20230609 NES 230609 2023 JUN 9 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators discuss new findings in Central Nervous System Diseases and Conditions - Generalized Epilepsy. [Extracted from the article]

Keywords: Jacksonville; State:Florida; United States; North and Central America; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drug Resistance; Drugs and Therapies; Electric Stimulation Therapy; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine; Medical Devices; Vagus Nerve Stimulation EN Jacksonville State:Florida United States North and Central America Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drug Resistance Drugs and Therapies Electric Stimulation Therapy Epilepsy Generalized Epilepsy Genetics Health and Medicine Medical Devices Vagus Nerve Stimulation 821 821 1 05/29/23 20230602 NES 230602 2023 JUN 2 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Central Nervous System Diseases and Conditions - Generalized Epilepsy are presented in a new report. According to news originating from Jacksonville, Florida, by NewsRx correspondents, research stated, "Neuromodulation in epilepsy is a proven treatment for people with drug-resistant focal epilepsy. [Extracted from the article]

Tabriz, Iran, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Epilepsy, Generalized Epilepsy, Genetics, Health and Medicine, Risk and Prevention The news reporters obtained a quote from the research from the Tabriz University of Medical Sciences, "Single nucleotide polymorphism (SNP) rs324420 is a common genetic polymorphism of the FAAH gene and has been associated with susceptibility to neurological conditions. Keywords: Tabriz; Iran; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine; Risk and Prevention EN Tabriz Iran Brain Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Generalized Epilepsy Genetics Health and Medicine Risk and Prevention 745 745 1 05/15/23 20230519 NES 230519 2023 MAY 19 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Researchers detail new data in Central Nervous System Diseases and Conditions - Generalized Epilepsy. [Extracted from the article]

Keywords: Tuebingen; Germany; Europe; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drugs and Therapies; Epilepsy; Epileptic Encephalopathy; Generalized Epilepsy; Genetics; Health and Medicine; Nervous System Diseases and Conditions; Neurologic Manifestations; Seizures; Therapeutics; Therapy EN Tuebingen Germany Europe Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drugs and Therapies Epilepsy Epileptic Encephalopathy Generalized Epilepsy Genetics Health and Medicine Nervous System Diseases and Conditions Neurologic Manifestations Seizures Therapeutics Therapy 147 147 1 05/08/23 20230508 NES 230508 2023 MAY 8 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Vaccine Week -- New research on Central Nervous System Diseases and Conditions - Generalized Epilepsy is the subject of a report. Keywords for this news article include: Europe, Germany, Genetics, Seizures, Tuebingen, Therapeutics, Drugs and Therapies, Health and Medicine, Generalized Epilepsy, Epileptic Encephalopathy, Neurologic Manifestations, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions. [Extracted from the article]

Keywords: Tuebingen; Germany; Europe; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drugs and Therapies; Epilepsy; Epileptic Encephalopathy; Generalized Epilepsy; Genetics; Health and Medicine; Nervous System Diseases and Conditions; Neurologic Manifestations; Seizures; Therapeutics; Therapy EN Tuebingen Germany Europe Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drugs and Therapies Epilepsy Epileptic Encephalopathy Generalized Epilepsy Genetics Health and Medicine Nervous System Diseases and Conditions Neurologic Manifestations Seizures Therapeutics Therapy N.PAG N.PAG 1 05/08/23 20230508 NES 230508 2023 MAY 9 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Vaccine Week -- New research on Central Nervous System Diseases and Conditions - Generalized Epilepsy is the subject of a report. Two variants causing developmental and epileptic encephalopathy showed a strong gain-of-function (hyperpolarizing shift of steady-state activation, strongly increased neuronal firing rate) and one variant causing benign familial infantile epilepsy or intermediate epilepsy showed a mild gain-of-function (defective fast inactivation, less increased firing). [Extracted from the article]

Keywords: Houston; State:Texas; United States; North and Central America; Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Generalized Epilepsy; Health and Medicine EN Houston State:Texas United States North and Central America Brain Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Generalized Epilepsy Health and Medicine 913 913 1 04/10/23 20230414 NES 230414 2023 APR 10 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- New research on Central Nervous System Diseases and Conditions - Generalized Epilepsy is the subject of a report. Houston, State:Texas, United States, North and Central America, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Epilepsy, Generalized Epilepsy, Health and Medicine. [Extracted from the article]

Keywords for this news article include: Fayoum University, Thalamus, Biochemicals, Biochemistry, Diencephalon, Health and Medicine, Generalized Epilepsy, Brain Diseases and Conditions, Central Nervous System Diseases and Conditions. Keywords: Biochemicals; Biochemistry; Brain; Brain Diseases and Conditions; Central Nervous System; Central Nervous System Diseases and Conditions; Chemicals; Diencephalon; Epilepsy; Generalized Epilepsy; Health and Medicine; Thalamus EN Biochemicals Biochemistry Brain Brain Diseases and Conditions Central Nervous System Central Nervous System Diseases and Conditions Chemicals Diencephalon Epilepsy Generalized Epilepsy Health and Medicine Thalamus 201 201 1 04/03/23 20230403 NES 230403 2023 APR 3 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Researchers detail new data in generalized epilepsy. [Extracted from the article]

Anterior Thalamic Nuclei, Brain Diseases and Conditions, Brain Research, Central Nervous System, Central Nervous System Diseases and Conditions, Diencephalon, Drug Resistance, Drugs and Therapies, Epilepsy, Genetics, Health and Medicine, Prosencephalon, Generalized Epilepsy Keywords: Anterior Thalamic Nuclei; Brain Diseases and Conditions; Brain Research; Central Nervous System; Central Nervous System Diseases and Conditions; Diencephalon; Drug Resistance; Drugs and Therapies; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine; Prosencephalon EN Anterior Thalamic Nuclei Brain Diseases and Conditions Brain Research Central Nervous System Central Nervous System Diseases and Conditions Diencephalon Drug Resistance Drugs and Therapies Epilepsy Generalized Epilepsy Genetics Health and Medicine Prosencephalon 2023 MAR 10 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Current study results on generalized epilepsy have been published. [Extracted from the article]

Keywords: Oslo; Norway; Europe; Genetics; Psychiatric; Schizophrenia; Health and Medicine; Risk and Prevention; Generalized Epilepsy; Brain Diseases and Conditions; Mental Health Diseases and Conditions; Central Nervous System Diseases and Conditions; Epilepsy; Mental Health; Psychiatry EN Oslo Norway Europe Genetics Psychiatric Schizophrenia Health and Medicine Risk and Prevention Generalized Epilepsy Brain Diseases and Conditions Mental Health Diseases and Conditions Central Nervous System Diseases and Conditions Epilepsy Mental Health Psychiatry New research on Central Nervous System Diseases and Conditions - Generalized Epilepsy is the subject of a report. Using conjunctional false discovery rate analysis, we identified 40 distinct loci jointly associated with epilepsies and psychiatric disorders at conjunctional false discovery rate <0.05, four of which were associated with all epilepsies and 39 with genetic generalized epilepsy. [Extracted from the article]

Brain Diseases and Conditions, Central Nervous System Diseases and Conditions, Drug Resistance, Drugs and Therapies, Epilepsy, Generalized Epilepsy, Genetics, Health and Medicine, Nervous System Diseases and Conditions, Neurologic Manifestations, Seizures Keywords: Brain Diseases and Conditions; Central Nervous System Diseases and Conditions; Drug Resistance; Drugs and Therapies; Epilepsy; Generalized Epilepsy; Genetics; Health and Medicine; Nervous System Diseases and Conditions; Neurologic Manifestations; Seizures EN Brain Diseases and Conditions Central Nervous System Diseases and Conditions Drug Resistance Drugs and Therapies Epilepsy Generalized Epilepsy Genetics Health and Medicine Nervous System Diseases and Conditions Neurologic Manifestations Seizures 2023 FEB 3 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on generalized epilepsy have been presented. [Extracted from the article]