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A recent study conducted at the University of Miami explored the use of platelet-rich plasma (PRP) as an adjuvant therapy to fractional ablative carbon dioxide lasers for treating atrophic acne scarring. The research suggests that combining PRP with laser therapy may offer superior clinical results compared to monotherapy, providing a more effective approach to managing acne scarring. This study, which analyzed randomized control trials from the past decade, highlights the potential benefits of this complementary treatment for individuals with acne vulgaris. [Extracted from the article]

Researchers at Jabir Ibn Hayyan Medical University conducted a study on the treatment of Inflammatory Acne Vulgaris (IAV) using a new pulsed wave mode of fractional microneedling radiofrequency device. The study involved 80 patients with moderate to severe acne, with one group receiving the new treatment and the other a placebo. Results showed significant improvement in the treated group's skin appearance compared to the control group, with minimal adverse effects reported. The research suggests that this advanced technique may offer an effective and safe treatment option for IAV. [Extracted from the article]

A patent application titled "Apparatus And Method For Treating Superficial Up To Deep Dermal Hyper Pigmentation Melasma, Acne And Anti-Aging Facial Skin Segments" was published online by inventors from Israel. The application focuses on providing effective and less painful treatments for conditions such as Melasma, Post Inflammatory Hyperpigmentation, Acne, and Anti-Aging. The proposed method involves a device that cools the treated area and utilizes ultra-thin needles for injections, aiming to improve treatment efficiency and reduce pain. The invention includes a detection unit, a cosmeceutical capsule, a microneedles array, and a cooling system to enhance the treatment process. [Extracted from the article]

A patent application by ProCell Therapies LLC for a "Micro-Channeling System" has been filed, focusing on the use of micro-needling for various skin conditions. The system aims to improve upon existing motorized micro-needling pens by addressing issues such as operator-dependent depth of penetration and backflow contamination. The system includes a pushrod, rotary motor, crank, and needle tip connector for a micro-needle array assembly. This innovation seeks to enhance the effectiveness and safety of micro-needling procedures for skin and hair improvement. [Extracted from the article]

A recent study conducted at the University of Brawijaya focused on the anti-acne potency of water-soluble chitosan peel-off gel masks against Propionibacterium acnes bacteria. The research aimed to find a natural antibacterial alternative to chemical antibiotics for treating acne. The study concluded that the peel-off mask with water-soluble chitosan was effective in inhibiting Propionibacterium acnes without causing skin irritation, making it a safe option for acne treatment. [Extracted from the article]

A recent study conducted at IRCCS Humanitas Research Hospital in Italy highlights the growing concern of antibiotic resistance in the treatment of acne vulgaris. The research emphasizes the need for alternative topical treatments, such as polyhexanide, to combat infections while reducing the risk of resistance development. Recommendations include the use of innovative and highly-tolerated treatments for various dermatological conditions, including acne. For more information, readers can access the full article in Dermatology Practical & Conceptual. [Extracted from the article]

Research from Uniwersytet Medyczny w Lublinie provides insights into acne vulgaris, a common skin disorder affecting adolescents globally. The condition is characterized by factors such as increased sebum production, bacterial colonization, and inflammation, leading to various skin lesions. Treatment options include topical and oral medications, with ongoing research exploring new therapies for long-lasting results. The study emphasizes the importance of addressing both physical and psychological consequences of acne. [Extracted from the article]

A patent application has been submitted by Karimi, Kian, and assigned to HealMD LLC for a method of treating acne and other inflammatory skin conditions using microneedling with a medical grade oil, specifically CBD oil. The method involves perforating the skin with microneedles and applying the oil to reduce inflammation and kill bacteria associated with acne. The invention challenges prior beliefs about microneedling over active acne and offers a comprehensive approach to acne treatment. The patent application details the steps involved in the treatment process and emphasizes the use of medical grade CBD oil for its anti-inflammatory, antimicrobial, and antioxidant properties. [Extracted from the article]

A recent study conducted at Geneva University Hospitals explored the impact of acne vulgaris on the quality of life and mental health of adolescents. The research found that factors such as physical activity and social support were associated with better acne-related quality of life and improved mental health outcomes. Conversely, excessive screen time and social media use were linked to lower quality of life and increased psychological distress among adolescents with acne. Dermatologists are encouraged to consider these findings in clinical practice to provide effective care for patients. [Extracted from the article]

Researchers from Shanghai Jiao Tong University School of Medicine conducted a study on the hair follicle microbiota in non-lesional areas of patients with moderate-to-severe acne vulgaris. The research found that the microbial community structure of hair follicles in acne patients differed from healthy individuals, with reduced microbial diversity in the acne group. Additionally, the study revealed an increased relative abundance of Staphylococcus species in the hair follicles of acne patients, suggesting a potential link between the microbiota and acne severity. [Extracted from the article]

ZitSticka, a skincare brand specializing in acne solutions, has unveiled a new vibrant look to enhance the consumer experience and make the journey to clear skin enjoyable. The rebrand includes color-blocking, neon accents, and clear labeling to help consumers choose the right product for their needs. ZitSticka's products use innovative technologies to address different stages of acne, and the brand is also engaging in guerrilla marketing strategies to reach a wider audience. [Extracted from the article]

The University of Nancy Hospital conducted research on drug-induced acne in patients with inflammatory bowel disease (IBD). The study highlighted the impact of corticosteroids and Janus kinase inhibitors (JAKi) on acne development in IBD patients, emphasizing the need for early management to prevent adverse effects on patient quality of life and treatment adherence. The research provides a practical guide for gastroenterologists to address drug-induced acne in IBD treatments, aiming to optimize patient care and treatment outcomes. [Extracted from the article]

Researchers at the Main Line Center for Laser Surgery in Ardmore, Pennsylvania, have found that a new 2910 nm fiber laser is safe and effective for improving acne scarring. The study involved 14 subjects with rolling and/or boxcar acne scars who received three treatments with the laser at 6-8 week intervals. Results showed a mean improvement of 47.3% in acne scars three months after the final treatment, with minimal side effects reported. The research has been peer-reviewed and published in Lasers in Surgery and Medicine. [Extracted from the article]

A patent application titled "Methods And Devices For Treating Skin Conditions" by inventor James M. Rynerson discusses the challenges in treating chronic eye conditions like blepharitis and dry eye, emphasizing the role of biofilms in bacterial survival and resistance to traditional treatments. The patent application describes a device for providing electrical therapy to the skin, aiming to vaporize biofilms and treat conditions such as acne, snoring, dry eye, and premature aging. The device includes electrodes, a power supply, and a controller to regulate the electrical signal, with the method involving applying different voltages to generate an electric current through the skin. [Extracted from the article]

A recent study published in the Journal of Investigative Dermatology found that many benzoyl peroxide (BPO) acne treatments contain high levels of benzene, a known carcinogen, due to degradation of the products when exposed to room temperature, heat, and UV light. The research suggests that refrigeration of BPO products may help reduce benzene formation and limit exposure. This discovery raises concerns about the safety of widely used acne treatments and highlights the importance of rigorous testing to protect consumers from harmful contaminants. [Extracted from the article]

A patent application by Yogesh Dandiker for "Sprayable Liquid Spironolactone Compositions" aims to provide a topical solution for treating acne and other conditions without the systemic side effects of oral spironolactone. The composition includes spironolactone, aliphatic solvents, water, film-forming excipients, and penetration enhancers to form a washable film on the skin. This innovative approach may offer a safe and effective treatment option for acne in both men and women, addressing a significant need in dermatology. [Extracted from the article]

A recent study conducted by the University of Miami explores the use of emerging laser and light-based therapies in the management of acne vulgaris. Acne vulgaris is a common skin disorder that primarily affects adolescents and young adults, with sebaceous gland overactivity being a key factor. The study highlights the potential benefits of laser and light-based therapies as alternative treatments for acne, aiming to address the limitations and side effects associated with traditional pharmacologic treatments. The research emphasizes the importance of exploring new modalities to improve acne management and patient outcomes. [Extracted from the article]

A recent study conducted at Wasit University in Iraq investigated the prevalence of acne vulgaris and the susceptibility of pathogenic bacteria to antibiotics. The study found that Staphylococcus epidermidis and Staphylococcus aureus were the most common bacteria causing acne, with S. epidermidis being more prevalent. The bacteria were found to form biofilms, making them resistant to antibiotics. The study also identified the antibiotics that were most effective against the bacteria, with doxycycline and clindamycin showing the highest sensitivity. The research provides valuable insights into the causes of acne vulgaris and the potential treatment options. [Extracted from the article]

A recent study conducted by researchers at Zhejiang Chinese Medicine University in China focused on personalized medicine for the treatment of acne vulgaris. The researchers used proteomic analyses and genetic tools to identify potential therapeutic targets for acne. They found that fatty acid synthase (FASN) exhibited a protective effect against acne, while tissue inhibitor of metalloproteinases 4 (TIMP4) was associated with an increased risk. These findings provide a foundation for the development of targeted acne treatments aligned with personalized medicine principles. Further validation through clinical research is needed. [Extracted from the article]

A recent study conducted by researchers at Iuliu Hatieganu University of Medicine and Pharmacy in Cluj Napoca, Romania, explored the association between vitamin D receptor (VDR) gene polymorphisms and cutaneous manifestations in women with polycystic ovary syndrome (PCOS). The study found that the VDR-FokI polymorphism CC genotype may have a protective role against acne and seborrhea in women with PCOS. Additionally, the dominant genotype of VDR-TaqI was associated with reduced oxidative stress in PCOS patients. This research provides valuable insights into the genetic factors that contribute to the development of skin manifestations in PCOS. [Extracted from the article]

A recent study conducted at GSL Medical College in Andhra Pradesh, India, examined the efficacy and safety of microneedling radiofrequency (MNRF) in the treatment of acne scars. The study involved 44 patients with acne scars who underwent four sessions of MNRF treatment. The results showed significant improvement in acne scar grading, with 70% of patients reporting excellent to good responses. Adverse effects such as post-treatment erythema and edema were observed in all patients, but overall, MNRF was found to be effective and safe for treating acne scars. [Extracted from the article]

A recent study conducted at Adam Mickiewicz University in Poznan, Poland, has explored the use of lipid nanocarriers in cosmetic formulations for the treatment of acne vulgaris and anti-aging therapies. The study found that the use of lipid nanocarriers enriched with retinol and oligopeptides resulted in stable semi-solid preparations that effectively reduced sebum secretion and decreased facial wrinkles. Additionally, the lipid nanoparticles themselves were found to have protective properties, reducing the irritating effects of retinol commonly associated with traditional retinoid therapies. This research provides valuable insights into the potential of nanotechnology in skincare treatments. [Extracted from the article]

A recent study conducted by the Department of Community Medicine in Sri Lanka focused on the translation, cultural adaptation, and validation of the Tamil version of the Cardiff Acne Disability Index (CADI). The CADI is a tool used globally to assess the quality of life (QoL) in patients with acne. The study found that the CADI-Tamil is a reliable and valid tool for assessing the QoL of Tamil-speaking patients with acne. This tool will help clinicians gain a better understanding of the patient's perspective on acne. [Extracted from the article]

A recent study conducted at the University of Arizona examined the use of quality-of-life measures in acne research. The study found that the Dermatology Life Quality Index (DLQI) was the most frequently used measure, followed by the Cardiff Acne Disability Index (CADI) and the Acne Quality-of-Life Questionnaire (Acne-QoL). The researchers noted that the use of these measures has increased significantly over the past decade, indicating a growing emphasis on patient-centered outcomes in acne research. The study concluded that quality-of-life indices can provide valuable insights into disease severity beyond objective clinical measurements. [Extracted from the article]

Crown Laboratories, Inc. is pleased to announce that its PanOxyl Acne Foaming Wash and PanOxyl Overnight Spot Patches have both received the 2024 Allure "Best of Beauty" Award. The PanOxyl Acne Foaming Wash won in the Body category for the second year in a row, solidifying its reputation as a leader in acne treatment. The Overnight Spot Patches also won in the "Best Steals" category, marking a significant milestone for the brand. These awards are highly regarded and involve a rigorous selection process conducted by experts in the beauty industry. PanOxyl is known as The Acne Authority and is committed to educating consumers about effective acne treatment options. The award-winning products can be purchased on Amazon and at major retailers. [Extracted from the article]

Kaya Clinic, a leading skin, hair, and body care chain in India, has launched an AI-powered app that offers personalized skin diagnosis. The app uses AI-based image analysis to evaluate skin parameters and provides a comprehensive analysis of skin health, identifying concerns such as aging, acne, scars, and blemishes. It is backed by Kaya's expertise on Indian skin types and a rich database of customer references, making it highly accurate for skin analysis. The app aims to enhance dermatologists' diagnostic skills and provide personalized skincare solutions. [Extracted from the article]

A recent study conducted by researchers at King Saud University in Riyadh, Saudi Arabia, highlights the health risks associated with the use of skin-whitening products containing mercury. The study focuses on a case of a 27-year-old woman who developed severe nodulocystic acne as a result of using a mercury-containing skin-whitening cream. Treatment with isotretinoin and prednisolone led to significant improvement within three months. The researchers emphasize the need for public awareness and stricter regulations to prevent the health hazards associated with mercury in skin-whitening products. [Extracted from the article]

A recent study conducted by researchers at Guilan University of Medical Sciences in Iran examined the effects of isotretinoin treatment on the serum lipid profile of adolescents and adults with acne vulgaris. The study found that while there was a significant increase in cholesterol and LDL levels, there were no significant changes in HDL and triglyceride levels. The researchers concluded that although a low dose of isotretinoin can be used with minimal concern for changes in lipid profile, caution should be exercised in long-term follow-up and treatment. This information may be useful for individuals considering isotretinoin as a treatment option for acne vulgaris. [Extracted from the article]

A clinical trial, NCT06602284, has been launched to evaluate the efficacy of the Dermapen 4(TM) microneedling device in conjunction with MG-CLR serum for treating acne over a 12-week period. The study aims to assess the change in acne severity using the modified GAGS scale compared to baseline. The trial is currently not recruiting participants and is expected to be completed by March 31, 2025. The study is being conducted by Equipmed USA LLC. [Extracted from the article]

A study conducted at the University of Alexandria in Egypt explored the effects of isotretinoin treatment on patients with acne vulgaris. The researchers found that isotretinoin treatment increased the expression of the transcription factor p53 in the skin and sebaceous glands of patients. This upregulation of p53 was associated with changes in gene expression related to the pathogenesis of acne vulgaris. The study suggests that increased p53-FoxO1 signaling caused by isotretinoin treatment may explain both the therapeutic effects and adverse effects of the drug. [Extracted from the article]

A recent study conducted at Zagazig University in Egypt examined the antibiotic susceptibility patterns of Cutibacterium acnes isolates in Egyptian patients with acne vulgaris. The study included 155 patients with moderate to severe acne, and the results showed high resistance rates to commonly prescribed antibiotics for acne, such as erythromycin, clindamycin, tetracycline, trimethoprim/sulfamethoxazole, and doxycycline. The researchers concluded that antibiotic resistance is a growing problem that may contribute to treatment failure in acne patients. This research has been peer-reviewed and provides valuable insights into the effectiveness of antibiotics in treating acne vulgaris. [Extracted from the article]

A recent study conducted by researchers at Queen Mary University of London explored the association between acne vulgaris (AV) and loss-of-function (LoF) filaggrin (FLG) gene mutations in a cohort of patients with atopic eczema (AE) of Bangladeshi ancestry in East London. The study found a significant reduction in the history of AV in patients with AE who had FLG LoF mutations compared to those without FLG mutations. Additionally, patients with severe AE were less likely to have a history of AV if they had an existing FLG LoF mutation. The research suggests that FLG LoF mutations may protect patients from developing AV in the context of AE. [Extracted from the article]

A recent study conducted in Madrid, Spain, investigated the efficacy of a cosmetic combination regimen for face care in women with acne-prone skin. The study enrolled 20 women with acne-prone mixed or oily skin and evaluated various parameters such as sebum content, skin radiance, skin profilometry, and pore size. The results showed that the tested regimen significantly reduced sebum content, improved skin radiance, and decreased pore size. The study also found positive effects on face sebum lipids composition, with an increase in ceramides and triacylglycerols and a decrease in fatty acids and oxidized fatty acids. Overall, the tested products were well-tolerated and 84% of the subjects reported a global clinical improvement. [Extracted from the article]

Researchers at UCLA have identified two dysregulated cellular pathways that contribute to the development of acne lesions. The pathways, known as the GRN-SORT1 axis in TREM2 macrophages and the IL-13-IL-13RA1 axis in keratinocytes, were found to be consistently upregulated in acne-affected skin. This discovery could potentially lead to the development of new acne treatments that target these pathways through gene therapy. The study highlights the importance of understanding the underlying signaling pathways involved in acne and offers hope for improved treatments in the future. [Extracted from the article]

A recent study conducted in West Bengal, India compared the effectiveness of 50% glycolic acid (GA) with 65% trichloroacetic acid (TCA) in treating atrophic acne scars using the chemical reconstruction of skin scars (CROSS) technique. The study found that 65% TCA produced better results, although it was associated with more adverse effects, such as acneiform eruption. The researchers suggest that GA could be a safer alternative to TCA with acceptable results. This study provides a basis for future research on different concentrations of GA as a CROSS agent. [Extracted from the article]

A recent study conducted in Riyadh, Saudi Arabia, examined the impact of acne scars on the quality of life and willingness to pay for treatments among adults. The study found that 63.4% of participants had acne scarring, and the most recognized treatment options were laser resurfacing and chemical peels. Participants expressed a willingness to pay for treatments due to the psychological impact of acne scars, income levels, and awareness of available modalities. The findings suggest a need for dermatologists to raise awareness about acne scar treatments and their effectiveness in improving quality of life. [Extracted from the article]

A new study conducted at Jamia Hamdard compared the effectiveness of 70% glycolic acid (GA) and 30% trichloroacetic acid (TCA) chemical peels in treating facial atrophic acne scars. The study involved 30 Asian patients with acne scars who underwent four peeling sessions over 16 weeks. The results showed that both GA and TCA peels significantly reduced acne scarring, but TCA peel was more effective according to physician and patient assessments. The study concluded that TCA peel is a well-tolerated and effective treatment for mild-to-moderate acne scars, while GA peel can be an alternative for patients who cannot tolerate TCA or prefer shorter downtime. [Extracted from the article]

A recent report discusses research on acne keloid, a condition characterized by inflammation in the scalp that leads to scar formation and hair loss. The study used various techniques, including RNA sequencing and spatial transcriptomics, to analyze scalp biopsy specimens from patients with active disease. The researchers identified specific cell populations, including fibroblasts and myeloid cells, that communicate through the SPP1 signaling network. Corticosteroids were found to reverse the gene expression signatures of these cells and reduce disease activity. The study suggests that the communication between fibroblasts and myeloid cells may contribute to the development of acne keloid. [Extracted from the article]

A study conducted by researchers at the University of Mosul in Iraq investigated the bacteria Cutibacterium acnes, which is a prominent cause of acne vulgaris. The study examined the spread of antibiotic resistance in treating acne and the evolutionary relationship between different isolates of Cutibacterium acnes. The researchers collected 125 samples from acne vulgaris patients and identified seven isolates of Cutibacterium acnes that were resistant to certain antibiotics. They also created an evolutionary tree based on the genetic similarity of the isolates. The study provides valuable insights into the genetics and susceptibility of Cutibacterium acnes strains. [Extracted from the article]

A patent has been issued for topical compositions that can be used to treat dermatological disorders such as acne vulgaris and post-inflammatory hyperpigmentation (PIH). The compositions contain ingredients like arginine, salicylic acid, and azelaic acid, which help resolve the signs and symptoms of these skin conditions quickly and effectively. The compositions are stable and can be safely applied for extended periods of time. They can be administered topically in the form of creams, ointments, serums, suspensions, or solutions. These novel therapies provide a safe and rapid treatment option for individuals affected by dermatological disorders. [Extracted from the article]

A new study from the Dermatology Clinic explores the effectiveness of reflectance confocal microscopy (RCM) in evaluating the reduction of acne lesions in patients treated with a product containing Silybum marianum fruit extract (SMFE). The study found that the investigational product, used in monotherapy over 60 days, resulted in a significant reduction in acne lesions and improvement in quality of life for patients. The use of RCM proved to be effective in assessing the therapeutic response in patients with moderate to severe acne. The study concludes that the monotherapy scheme with the investigational product containing SMFE is safe and effective for acne treatment. [Extracted from the article]