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523 results on '"Ying, Li"'

1. Quality of life and death anxiety among caregivers of patients with advanced cancer: the mediating effect of trait anxious personality and the moderating effect of social support.

Author: Ying, Li, Yuyu, Duan, Qinqin, Zhao, and Zhihuan, Zhou
Abstract: Purpose: To explore the mediating role of trait anxious personality in the association between quality of life (QoL) and death anxiety (DA), as well as to test the moderating effect of social support in the mediation model. Methods: The Death Anxiety Scale, Quality of Life Scale, State-Trait Anxiety Scale, and Social Support Rating Scale were used to measure 588 family caregivers of advanced cancer patients. We then constructed a moderated mediation model. Results: The presence of QoL was negatively associated with DA (β = − 0.67, p < 0.01). Trait anxious personality partially mediated the relationship between QoL and DA (indirect effect β = − 0.08, p < 0.01). Social support moderated both the antecedent and subsequent segments of the mediating paths of “QoL → trait anxious personality → DA” and the direct relationship between QoL and DA. Among caregivers with a low level of social support, the mediating effect coefficient of trait anxious personality was higher at 0.25 (95% confidence interval (CI): 0.059–0.182), in contrast to caregivers with a high level of social support, where the mediating effect coefficient of trait anxious personality was 0.11 (95% CI: 0.029–0.072). Conclusion: QoL is directly associated with an increased risk of DA and indirectly related to DA by increasing the risk of trait anxious personality among caregivers. Social support can moderate the mediating effect of trait anxious personality and the relationship between QoL and DA. The intervention strategy for preventing DA among caregivers who have encountered QoL reduction should focus on reducing trait anxious personality and social support. [ABSTRACT FROM AUTHOR]
Published: 2024
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2. USP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer.

Author: Wang, Qian-Lan, Lu, Shun-Yuan, Xu, Dan-Dan, Ma, Jin-Xia, Guo, Rui, Zhang, Lu, Tang, Ling-Yun, Shen, Yan, Shen, Chun-Ling, Wang, Jin-Jin, Wu, Ying-Li, Lu, Li-Ming, Wang, Zhu-Gang, and Zhang, Hong-Xin
Subjects: TUMOR-infiltrating immune cells, PROSTATE cancer, CYTOTOXIC T cells, IMMUNE response, KILLER cells, ANDROGEN receptors, TUMOR microenvironment
Abstract: This study investigates the role of USP47, a deubiquitinating enzyme, in the tumor microenvironment and its impact on antitumor immune responses. Analysis of TCGA database revealed distinct expression patterns of USP47 in various tumor tissues and normal tissues. Prostate adenocarcinoma showed significant downregulation of USP47 compared to normal tissue. Correlation analysis demonstrated a positive association between USP47 expression levels and infiltrating CD8+ T cells, neutrophils, and macrophages, while showing a negative correlation with NKT cells. Furthermore, using Usp47 knockout mice, we observed a slower tumor growth rate and reduced tumor burden. The absence of USP47 led to increased infiltration of immune cells, including neutrophils, macrophages, NK cells, NKT cells, and T cells. Additionally, USP47 deficiency resulted in enhanced activation of cytotoxic T lymphocytes (CTLs) and altered T cell subsets within the tumor microenvironment. These findings suggest that USP47 plays a critical role in modulating the tumor microenvironment and promoting antitumor immune responses, highlighting its potential as a therapeutic target in prostate cancer. [ABSTRACT FROM AUTHOR]
Published: 2024
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3. The Effect of Glycine and N-Acetylcysteine on Oxidative Stress in the Spinal Cord and Skeletal Muscle After Spinal Cord Injury.

Author: Xu, Xin, Zhang, Chun-Jia, Talifu, Zuliyaer, Liu, Wu-Bo, Li, Ze-Hui, Wang, Xiao-Xin, Du, Hua-Yong, Ke, Han, Yang, De-Gang, Gao, Feng, Du, Liang-Jie, Yu, Yan, Jing, Ying-Li, and Li, Jian-Jun
Subjects: SPINAL cord injuries, SPINAL cord, SKELETAL muscle, GLYCINE agents, OXIDATIVE stress
Abstract: Oxidative stress is a frequently occurring pathophysiological feature of spinal cord injury (SCI) and can result in secondary injury to the spinal cord and skeletal muscle atrophy. Studies have reported that glycine and N-acetylcysteine (GlyNAC) have anti-aging and anti-oxidative stress properties; however, to date, no study has assessed the effect of GlyNAC in the treatment of SCI. In the present work, we established a rat model of SCI and then administered GlyNAC to the animals by gavage at a dose of 200 mg/kg for four consecutive weeks. The BBB scores of the rats were significantly elevated from the first to the eighth week after GlyNAC intervention, suggesting that GlyNAC promoted the recovery of motor function; it also promoted the significant recovery of body weight of the rats. Meanwhile, the 4-week heat pain results also suggested that GlyNAC intervention could promote the recovery of sensory function in rats to some extent. Additionally, after 4 weeks, the levels of glutathione and superoxide dismutase in spinal cord tissues were significantly elevated, whereas that of malondialdehyde was significantly decreased in GlyNAC-treated animals. The gastrocnemius wet weight ratio and total antioxidant capacity were also significantly increased. After 8 weeks, the malondialdehyde level had decreased significantly in spinal cord tissue, while reactive oxygen species accumulation in skeletal muscle had decreased. These findings suggested that GlyNAC can protect spinal cord tissue, delay skeletal muscle atrophy, and promote functional recovery in rats after SCI. [ABSTRACT FROM AUTHOR]
Published: 2024
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4. Visualizing the interfacial-layer-based epitaxial growth process toward organic core-shell architectures.

Author: Zhuo, Ming-Peng, Wei, Xiao, Li, Yuan-Yuan, Shi, Ying-Li, He, Guang-Peng, Su, Huixue, Zhang, Ke-Qin, Guan, Jin-Ping, Wang, Xue-Dong, Wu, Yuchen, and Liao, Liang-Sheng
Abstract: Organic heterostructures (OHTs) with the desired geometry organization on micro/nanoscale have undergone rapid progress in nanoscience and nanotechnology. However, it is a significant challenge to elucidate the epitaxial-growth process for various OHTs composed of organic units with a lattice mismatching ratio of > 3%, which is unimaginable for inorganic heterostructures. Herein, we have demonstrated a vivid visualization of the morphology evolution of epitaxial-growth based on a doped interfacial-layer, which facilitates the comprehensive understanding of the hierarchical self-assembly of core-shell OHT with precise spatial configuration. Significantly, the barcoded OHT with periodic shells obviously illustrate the shell epitaxial-growth from tips to center parts along the seeded rods for forming the core-shell OHT. Furthermore, the diameter, length, and number of periodic shells were modulated by finely tuning the stoichiometric ratio, crystalline time, and temperature, respectively. This epitaxial-growth process could be generalized to organic systems with facile chemical/structural compatibility for forming the desired OHTs.Organic heterostructures with controlled geometry on the micro and nanoscale are important in nanotechnology, but epitaxial growth processes with high lattice mismatching are challenging to achieve. Here, the authors report a visualisation process for morphology evolution on epitaxial growth. [ABSTRACT FROM AUTHOR]
Published: 2024
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5. Multi-physical fields distribution in billet during helical electromagnetic stirring: A numerical simulation research.

Author: Dong Pan, Qing-tao Guo, Kai-lun Zhang, Fu-zhi Yu, Yu-ying Li, and Yu-bao Xiao
Subjects: COMPUTER simulation, CONTINUOUS casting, LIQUID metals, ELECTROMAGNETIC shielding, FLOW velocity
Abstract: Electromagnetic stirring is one of the widely applied techniques to modify the quality of casting billets. Different from conventional rotate stirring, the helical stirring is more professional in assisting multi-dimensional flow of molten metal and eliminating solidification defects. In this study, the single-winding helical stirring (SWHS) was introduced, offering advantages such as smaller volume and lower electromagnetic shielding compared to traditional helical stirring methods. Following a comprehensive numerical simulation, the stirring parameters of SWHS were adjusted to yoke inclination angle of 43° and frequency of 12 Hz. The higher electromagnetic force and flow velocity in drawing direction, as well as the lower temperature gradient induced by the SWHS, are positive factors for homogeneous solidification of billet. The experimental results on Al-8%Si alloy and 0.4%C-1.1%Mn steel demonstrate that compared to rotate stirring, the SWHS process can induce better billet quality and is more effective in accelerating the equiaxed expansion and reducing element segregation. The SWHS process can enhance the equiaxed ratio of the billet by 58.3% and reduce segregation degree of carbon element by 10.97%. Consequently, SWHS holds great promise as a potential approach for improving the quality of continuous casting billets. [ABSTRACT FROM AUTHOR]
Published: 2024
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6. Safety and Efficacy of Ixekizumab in Chinese Adults with Moderate-to-Severe Plaque Psoriasis: A Prospective, Multicenter, Observational Study.

Author: Ying, Li, Suyun, Ji, Yanhua, Liang, Yunsheng, Liang, Li, Deng, Lin, Dang, Chengzhi, Lv, Bingjiang, Lin, Furen, Zhang, Wendi, Shi, Jinnan, Li, Yu, Dong, Guanshen, Dou, and Shi, Yuling
Abstract: Introduction: Psoriasis, an incurable chronic inflammatory disease, affects over 6 million people in China. Ixekizumab, a monoclonal antibody against interleukin-17A, has demonstrated efficacy and safety for the treatment of moderate-to-severe plaque psoriasis, although limited data are available regarding its use in routine clinical practice in China. We investigated the real-world application of ixekizumab in China. Methods: Adults (≥ 18 years) with moderate-to-severe plaque psoriasis prescribed ixekizumab in routine clinical practice were enrolled in this prospective, observational, single-arm, multicenter, post-marketing surveillance study. The primary endpoint was the safety of ixekizumab at week 12. The effectiveness of ixekizumab, based on the Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI), was assessed as a secondary endpoint. Results: In total, 666 patients were enrolled; 663 were included in the safety analysis, and 612 in the effectiveness analysis. At least one adverse event (AE) was reported by 42.7% (283/663) of patients, most of which were mild (242/283, 85.5%), and 32.7% (217/663) of patients reported AEs related to study treatment. The most frequently reported AEs were injection site reactions. AEs led to discontinuation in five patients (0.8%). Only three patients had a serious AE. Mean ± standard deviation (SD) change from baseline in PASI score was reduction in 10.79 ± 9.55 at week 2 and 16.80 ± 12.15 at week 12. At week 2, 63.7% of patients achieved PASI 50. At week 12, 93.2%, 77.4%, and 45.1% of patients achieved PASI 75, PASI 90, and PASI 100, respectively. Mean ± SD change from baseline in DLQI was reduction in 5.91 ± 6.27 at week 2 and 9.76 ± 7.16 at week 12. DLQI 0/1 was achieved by 19.8% and 59.9% of patients at week 2 and 12, respectively. Conclusion: Ixekizumab was well tolerated and effective in real-world clinical practice in Chinese adults with moderate-to-severe plaque psoriasis. [ABSTRACT FROM AUTHOR]
Published: 2023
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7. 25-Hydroxyvitamin D Is Associated with Islet Homeostasis in Type-2 Diabetic Patients with Abdominal Obesity.

Author: Li, Qing, Zhang, Wen, Han, Bing, Wang, Yu-ying, Wan, Heng, Zhang, Min, Wang, Ning-jian, and Lu, Ying-li
Published: 2023
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8. The effects of job characteristics on physicians' orientation toward lifelong learning.

Author: Lin, Ying-Li, Chen, Huey-Ling, Chen, Yen-Yuan, Cheng, Shao-Yi, Chen, Wei-Li, Chiu, Yu-Chun, and Chiu, Yen-Lin
Subjects: CONTINUING education, PHYSICIANS' attitudes, MEDICAL centers, SOCIAL support
Abstract: With the rapidly growing body of medical knowledge, physicians must engage in lifelong learning. Physicians' orientation toward lifelong learning is of crucial importance. This study aimed to explore the effects of job characteristics on physicians' lifelong learning. A multicenter study collecting data from physicians from three medical centers in Taiwan was performed. A total of 321 physicians were surveyed with the Chinese version of the Job Content Questionnaire (C-JCQ) and the revised Jefferson Scale of Physician Lifelong Learning (JeffSPLL) to assess their job characteristics (i.e., job demands, job control, social support) and orientation toward lifelong learning. Exploratory factor analysis was employed to validate both questionnaires. Hierarchical regression was utilized to explore the relationship of job characteristics and predictors with physicians' lifelong learning. The results revealed that job demands (β = 0.10), job control (β = 0.19), social support from supervisors (β = 0.16), the interaction of job demands × job control (β = − 0.11) and the interaction of job demands × social support from colleagues (β = 0.13) were significantly (p <.05, p <.001) related to lifelong learning. Moreover, physicians in the active group (high demand, high control) possessed a stronger orientation toward lifelong learning (mean = 3.57) than those in the low-strain group (mean = 3.42), high-strain group (mean = 3.39) and passive group (mean = 3.20). In conclusion, examining physicians' job demands, job control and social support helps us to understand their orientation toward lifelong learning and may provide insight to improve educational strategies. [ABSTRACT FROM AUTHOR]
Published: 2023
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9. The Role of CCL3 in the Pathogenesis of Rheumatoid Arthritis.

Author: Yang, Ying-Li, Li, Xiao-Feng, Song, Biao, Wu, Sha, Wu, Yuan-Yuan, Huang, Cheng, and Li, Jun
Subjects: *PATHOGENESIS, *JOINTS (Anatomy), *SYNOVIAL fluid, *AUTOIMMUNE diseases, *CARTILAGE, *RHEUMATOID arthritis
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease of unexplained causes. Its pathological features include synovial tissue hyperplasia, inflammatory cell infiltration in joint cavity fluid, cartilage bone destruction, and joint deformation. C–C motif chemokine ligand 3 (CCL3) belongs to inflammatory cell chemokine. It is highly expressed in inflammatory immune cells. Increasingly, studies have shown that CCL3 can promote the migration of inflammatory factors to synovial tissue, the destruction of bone and joint, angiogenesis, and participate in the pathogenesis of RA. These symptoms indicate that the expression of CCL3 is highly correlated with RA disease. Therefore, this paper reviews the possible mechanism of CCL3 in the pathogenesis of RA, which may provide some new insights for the diagnosis and treatment of RA. [ABSTRACT FROM AUTHOR]
Published: 2023
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10. LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway.

Author: Wang, Yibo, Hang, Kai, Ying, Li, Wu, Jiaqi, Wu, Xiaoyong, Zhang, Weijun, Li, Lijun, Wang, Zhongxiang, Bai, Jinwu, Gao, Xiang, Xue, Deting, and Pan, Zhijun
Subjects: WNT signal transduction, ADIPOGENESIS, FRACTURE healing, MESENCHYMAL stem cells, CELLULAR signal transduction, TIBIAL fractures, OLEIC acid, MEMBRANE proteins
Abstract: Chaperone-mediated autophagy (CMA) plays multiple roles in cell metabolism. We found that lysosome-associated membrane protein type 2A (LAMP2A), a crucial protein of CMA, plays a key role in the control of mesenchymal stem cell (MSC) adipo-osteogenesis. We identified a differentially expressed CMA gene (LAMP2) in GEO datasets (GSE4911 and GSE494). Further, we performed co-expression analyses to define the relationships between CMA components genes and other relevant genes including Col1a1, Runx2, Wnt3 and Gsk3β. Mouse BMSCs (mMSCs) exhibiting Lamp2a gene knockdown (LA-KD) and overexpression (LA-OE) were created using an adenovirus system; then we investigated LAMP2A function in vitro by Western blot, Oil Red staining, ALP staining, ARS staining and Immunofluorescence analysis. Next, we used a modified mouse model of tibial fracture to investigate LAMP2A function in vivo. LAMP2A knockdown in mMSCs decreased the levels of osteogenic-specific proteins (COL1A1 and RUNX2) and increased those of the adipogenesis markers PPARγ and C/EBPα; LAMP2A overexpression had the opposite effects. The active-β-catenin and phospho-GSK3β (Ser9) levels were upregulated by LAMP2A overexpression and downregulated by LAMP2A knockdown. In the mouse model of tibial fracture, mMSC-overexpressing LAMP2A improved bone healing, as demonstrated by microcomputed tomography and histological analyses. In summary, LAMP2A positively regulates mMSC osteogenesis and suppresses adipo-osteogenesis, probably via Wnt/β-catenin/GSK3β signaling. LAMP2A promoted fracture-healing in the mouse model of tibial fracture. Key messages: • LAMP2 positively regulates the mBMSCs osteogenic differentiation. • LAMP2 negatively regulates the mBMSCs adipogenic differentiation. • LAMP2 regulates mBMSCs osteogenesis via Wnt/β-catenin/GSK3β signaling pathway. • LAMP2 overexpression mBMSCs promote the fracture healing. [ABSTRACT FROM AUTHOR]
Published: 2023
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11. Reconstruction of power spectrum of primordial curvature perturbations on small scales from primordial black hole binaries scenario of LIGO/VIRGO detection.

Author: Wang, Xinpeng, Zhang, Ying-li, Kimura, Rampei, and Yamaguchi, Masahide
Abstract: As a candidate bound for the Binary Black Hole (BBH) merger events detected by LIGO/Virgo, Primordial Black Holes (PBHs) provide a useful tool to investigate the primordial curvature perturbations on small scales. Using the GWTC-1 to GWTC-3 catalogs, under the scenario that PBHs originate from large primordial curvature perturbations on small scales during inflationary epoch, we for the first time reconstruct the power spectrum of primordial curvature perturbations on small scales. It is found that the value of the amplitude of the primordial power spectrum is enhanced to O ( 10 − 2 ) on scales O (1) pc . This may imply the validity of PBH as a possible BBH merger candidate. [ABSTRACT FROM AUTHOR]
Published: 2023
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12. Contact stiffness attenuation model of bolted joint based on time-varying uncertainty.

Author: Nana, Niu, Yongsheng, Zhao, Congbin, Yang, Hongchao, Wu, Ying, Li, and Tao, Zhang
Subjects: BOLTED joints, MECHANICAL models, SURFACE states
Abstract: Various deterministic and uncertain factors are widely present in mechanical equipment and their working conditions. Attenuation of the contact stiffness of bolted joints caused by bolt loosening will directly affect the dynamic characteristics of the joint surface and the working state of the equipment. This paper proposes a contact stiffness attenuation model that considers time-varying uncertainty of the bolt pre-tightening force as a theoretical basis for designing the initial bolt pre-tightening force and secondary tightening strategies. First, the microscopic contact mechanism of the bolted joint surface was revealed, and then a joint contact load and contact stiffness model based on Hertz contact theory and fractal theory was established. A nonlinear mechanical model of the bolted contact surface was obtained. Considering the decrease in bolt pre-tightening force during service, a contact stiffness attenuation law for bolted joints is explored, and a model of the connection reliability of group bolt joints with time-varying uncertainty is established. The bolt pre-tightening force of a railway locomotive was taken as an example and the connection reliability of group bolt structures was predicted, and it is defined that the bolted structure fails when the contact stiffness drops to 80% of the initial value, and the reliability of the group bolts will drop sharply on the 15th day after service, and will almost completely fail on the 22nd day. The proposed theory improves the accuracy of contact modeling and provides a new direction for bolt tightening strategies. [ABSTRACT FROM AUTHOR]
Published: 2023
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13. Optimized Cationic Lipid-assisted Nanoparticle for Delivering CpG Oligodeoxynucleotides to Treat Hepatitis B Virus Infection.

Author: Chen, Yi-Fang, Wang, Yan, Wang, Yue, Luo, Ying-Li, Lu, Zi-Dong, Du, Xiao-Jiao, Xu, Cong-Fei, and Wang, Jun
Subjects: CATIONIC lipids, HEPATITIS B, CPG nucleotides, HEPATITIS associated antigen, NANOPARTICLES, HEPATITIS B virus
Abstract: Purpose: Hepatitis B virus (HBV) infection is such a global health problem that hundreds of millions of people are HBV carriers. Current anti-viral agents can inhibit HBV replication, but can hardly eradicate HBV. Cytosine-phosphate-guanosine (CpG) oligodeoxynucleotides (ODNs) are an adjuvant that can activate plasmacytoid dendritic cells (pDCs) and conventional dendritic cells (cDCs) to induce therapeutic immunity for HBV eradication. However, efficient delivery of CpG ODNs into pDCs and cDCs remains a challenge. In this study, we constructed a series of cationic lipid-assisted nanoparticles (CLANs) using different cationic lipids to screen an optimal nanoparticle for delivering CpG ODNs into pDCs and cDCs. Methods: We constructed different CLANCpG using six cationic lipids and analyzed the cellular uptake of different CLANCpG by pDCs and cDCs in vitro and in vivo, and further analyzed the efficiency of different CLANCpG for activating pDCs and cDCs in both wild type mice and HBV-carrier mice. Results: We found that CLAN fabricated with 1,2-Dioleoyl-3-trimethylammonium propane (DOTAP) showed the highest efficiency for delivering CpG ODNs into pDCs and cDCs, resulting in strong therapeutic immunity in HBV-carrier mice. By using CLANCpG as an immune adjuvant in combination with the injection of recombinant hepatitis B surface antigen (rHBsAg), HBV was successfully eradicated and the chronic liver inflammation in HBV-carrier mice was reduced. Conclusion: We screened an optimized CLAN fabricated with DOTAP for efficient delivery of CpG ODNs to pDCs and cDCs, which can act as a therapeutic vaccine adjuvant for treating HBV infection. [ABSTRACT FROM AUTHOR]
Published: 2023
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14. Ecogenomics reveals viral communities across the Challenger Deep oceanic trench.

Author: Zhou, Ying-Li, Mara, Paraskevi, Vik, Dean, Edgcomb, Virginia P., Sullivan, Matthew B., and Wang, Yong
Subjects: *SUBMARINE trenches, *DEEP ecology, *SULFUR metabolism, *ECOLOGICAL impact, *VIRAL shedding, *HYDROSTATIC pressure, *PHYSIOLOGICAL adaptation, *NITROGEN cycle, MARIANA Trench
Abstract: Despite the environmental challenges and nutrient scarcity, the geographically isolated Challenger Deep in Mariana trench, is considered a dynamic hotspot of microbial activity. Hadal viruses are the least explored microorganisms in Challenger Deep, while their taxonomic and functional diversity and ecological impact on deep-sea biogeochemistry are poorly described. Here, we collect 13 sediment cores from slope and bottom-axis sites across the Challenger Deep (down to ~11 kilometers depth), and identify 1,628 previously undescribed viral operational taxonomic units at species level. Community-wide analyses reveals 1,299 viral genera and distinct viral diversity across the trench, which is significantly higher at the bottom-axis vs. slope sites of the trench. 77% of these viral genera have not been previously identified in soils, deep-sea sediments and other oceanic settings. Key prokaryotes involved in hadal carbon and nitrogen cycling are predicted to be potential hosts infected by these viruses. The detected putative auxiliary metabolic genes suggest that viruses at Challenger Deep could modulate the carbohydrate and sulfur metabolisms of their potential hosts, and stabilize host's cell membranes under extreme hydrostatic pressures. Our results shed light on hadal viral metabolic capabilities, contribute to understanding deep sea ecology and on functional adaptions of hadal viruses for future research. Analysis of 13 sediment cores from the Challenger Deep of Marian Trench (down to 11 kilometers depth) identified distinct operational taxonomic units and relevant auxiliary metabolic genes, providing further insight into deep-sea viral metabolic capabilities and ecology. [ABSTRACT FROM AUTHOR]
Published: 2022
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15. Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response.

Author: Wang, Dong-Rui, Wu, Xian-Lin, and Sun, Ying-Li
Published: 2022
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16. Stability of the Heisenberg Product on Symmetric Functions.

Author: Ying, Li
Subjects: *SCHUR functions, *KRONECKER products, *SYMMETRIC functions
Abstract: The Heisenberg product is an associative product defined on symmetric functions which interpolates between the usual product and the Kronecker product. In 1938, Murnaghan discovered that the Kronecker product of two Schur functions stabilizes. We prove an analogous result for the Heisenberg product of Schur functions. [ABSTRACT FROM AUTHOR]
Published: 2022
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17. Occurrence of polycyclic aromatic hydrocarbons (PAHs) in the seafood from an important fishing area in the East China Sea and a comparison between seafood from different origins.

Author: Qian, Wang, Dequan, Lu, Yiran, Xiong, Fei, Peng, Juan-ying, Li, Feng, Wu, Yanping, Chu, Ruihua, Sun, and Siquan, Tian
Subjects: SEAFOOD, MARINE food chain, FOOD chains, METROPOLITAN areas, POLYCYCLIC aromatic hydrocarbons, MARINE debris, FOSSIL fuels, FISHING
Abstract: Polycyclic aromatic hydrocarbons (PAHs) were analyzed in a variety of coastal marine seafood from the Wentai fishing area, which is in proximity to highly urbanized areas and provides a significant portion of the marine aquatic products in Eastern China. Specifically, total PAHs ranged from 320 to 2500 ng/g d.w., whereas carcinogenic PAHs ranged from 21 to 92 ng/g d.w. According to the source diagnosis, the PAHs in the seafood were generally from sources highly related to fossil fuel. Thus, it is necessary to control the unintentional use of fossil fuels and optimize the energy structure in the terrestrial area nearby. Moreover, the food chain structure and the environmental behavior of PAHs through the food chain, which are relevant to dietary risk, were assessed. The δ15N values fell in a narrow range, which indicates a relatively short food chain, which is due to overfishing in this area. Furthermore, in this shortened food chain, the trophic magnification factors (TMFs) ranged from 0.23 to 6.6, which were generally higher than those in more complex food chains. The cancer risk (ILCR) ranged from 2.2 × 10−8 to 2.2 × 10−6. It is noted that the carcinogenic risk of consuming yellow croaker, which is one of the most popular seafood among people on the east coast of China, was the highest. In conclusion, trophic magnification implied a possible elevated risk through this marine food chain, and overfishing may have increased the uncertainty associated with TMF estimations. [ABSTRACT FROM AUTHOR]
Published: 2022
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18. Exploring cosmic origins through primordial black hole mass functions.

Author: Zhang, Ying-Li
Published: 2024
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19. WSN Clustering Routing Algorithm Based on Hybrid Genetic Tabu Search.

Author: Xiuwu, Yu, Ying, Li, Yong, Liu, and Hao, Yu
Subjects: ROUTING algorithms, GENETIC algorithms, TABU search algorithm, WIRELESS sensor networks, ENERGY consumption, DATA transmission systems, COST functions
Abstract: In order to effectively prolong the lifetime of wireless sensor network and balance network energy consumption, a WSN clustering routing algorithm based on hybrid genetic tabu search (CRGT) is proposed. Firstly, in the stage of cluster head election, two parameters, the residual energy of nodes and the distance from nodes to Sink node, are introduced to optimize the threshold function to make the cluster head election more reasonable. Secondly, in the stage of clustering, ordinary nodes join the cluster with the lowest cost according to the cost function to balance the node energy. Finally, a hybrid genetic tabu search algorithm is introduced to select the optimal path with the least energy consumption during data transmission. The simulation results show that, compared with the other two clustering routing algorithms, CRGT algorithm effectively prolongs the network lifetime, and the energy consumption is more balanced. [ABSTRACT FROM AUTHOR]
Published: 2022
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20. FSH may mediate the association between HbA1c and bone turnover markers in postmenopausal women with type 2 diabetes.

Author: Zha, Ke-xi, An, Zeng-mei, Ge, Shao-hong, Cai, Jian, Zhou, Ying, Ying, Rong, Zhou, Ji, Gu, Tao, Guo, Hui, Zhao, Yan, Wang, Ning-jian, and Lu, Ying-li
Subjects: BONE remodeling, TYPE 2 diabetes, POSTMENOPAUSE, GLYCOSYLATED hemoglobin, INHIBIN, BODY mass index, HYPERGLYCEMIA, VITAMIN D
Abstract: Introduction: Recent studies in postmenopausal women have found associations of follicle-stimulating hormone (FSH) levels with both glucose metabolism and bone turnover. The objective of the study was to investigate whether FSH may contribute to suppressed bone turnover markers (BTMs) in postmenopausal women with type 2 diabetes (T2D). Materials and methods: 888 postmenopausal women with T2D, 352 nondiabetes (prediabetes plus normoglycemia) were included from the METAL study. HbA1c, sex hormones, 25-hydroxy vitamin D (25(OH)D), serum procollagen type I N-terminal propeptide (P1NP), and β-C-terminal telopeptide (β-CTX) were measured. Results: P1NP and β-CTX decreased in postmenopausal T2D women compared with nondiabetes controls (both p < 0.001). The major factors responsible for the changes in P1NP were HbA1c (β = − 0.050, p < 0.001), 25(OH)D (β = − 0.003, p = 0.006), FSH (β = 0.001, p = 0.044) and metformin (β = − 0.109, p < 0.001), for β-CTX were HbA1c (β = − 0.049, p < 0.001), body mass index (BMI) (β = − 0.011, p = 0.005), 25(OH)D (β = − 0.003, p = 0.003), FSH (β = 0.002, p = 0.022) and metformin (β = − 0.091, p = 0.001) in postmenopausal T2D women based on multivariate regression analysis. With the increase in HbA1c, FSH decreased significantly (p for trend < 0.001). Mediation analysis demonstrated that FSH partly mediated the suppression of LnP1NP and Lnβ-CTX by HbA1c (β = − 0.009 and − 0.010, respectively), and Lnβ-CTX by BMI (β = − 0.015) when multiple confounders were considered (all p < 0.05). Conclusion: HbA1c was the crucial determinant contributing to the suppression of BTMs. FSH might play a novel mediation role in BTM suppression due to HbA1c or BMI. [ABSTRACT FROM AUTHOR]
Published: 2022
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21. The clues in the news media coverage: detecting Chinese collective action trend from a text analytics research framework.

Author: Ying, Li, Linlin, Li, and Qianqian, Li
Subjects: COLLECTIVE action, SOCIAL adjustment, TEXT mining, NEWS websites, MACHINE learning
Abstract: With the adjustment of social relations and interest patterns brought about by the comprehensive deepening reform in China, new and old contradictions are intertwined, various risks are increased, collective actions occasionally occur, and some new trends are observed. However, due to there is no authoritative database of collective action in China, it is difficult to observe the trend of collective actions. There has been significant research show that news coverage is an effective way to obtain collective action information. Thus, we examine the recent news coverage shift in terms of collective action. We collected 5354 news coverages from 2014 to 2018. Then, we constructed a collective action domain-specific word dictionary and presented a method to automatically detect temporal, spatial, and topical trends of collective action. The proposed framework is based on text mining analysis that collects data from news outlets and extracts valuable data for perceiving the collective action trends. The results show that the proposed method is an effective tool to identify the trends in collective action via machine learning. [ABSTRACT FROM AUTHOR]
Published: 2022
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22. Microbiomes in the Challenger Deep slope and bottom-axis sediments.

Author: Zhou, Ying-Li, Mara, Paraskevi, Cui, Guo-Jie, Edgcomb, Virginia P., and Wang, Yong
Subjects: MARIANA Trench, PROKARYOTIC genomes, SEDIMENTS, WATER depth, MICROBIAL communities, HEAVY metals
Abstract: Hadal trenches are the deepest and most remote regions of the ocean. The 11-kilometer deep Challenger Deep is the least explored due to the technical challenges of sampling hadal depths. It receives organic matter and heavy metals from the overlying water column that accumulate differently across its V-shaped topography. Here, we collected sediments across the slope and bottom-axis of the Challenger Deep that enable insights into its in situ microbial communities. Analyses of 586 metagenome-assembled genomes retrieved from 37 metagenomes show distinct diversity and metabolic capacities between bottom-axis and slope sites. 26% of prokaryotic 16S rDNA reads in metagenomes were novel, with novelty increasing with water and sediment depths. These predominantly heterotrophic microbes can recycle macromolecules and utilize simple and complex hydrocarbons as carbon sources. Metagenome and metatranscriptome data support reduction and biotransformation of arsenate for energy gain in sediments that present a two-fold greater accumulation of arsenic compared to non-hadal sites. Complete pathways for anaerobic ammonia oxidation are predominantly identified in genomes recovered from bottom-axis sediments compared to slope sites. Our results expand knowledge of microbially-mediated elemental cycling in hadal sediments, and reveal differences in distribution of processes involved in nitrogen loss across the trench. The V-shaped Challenger Deep in the Mariana Trench is the deepest part of the world's oceans. Using 586 prokaryotic metagenome-assembled genomes and metatranscriptomic data, this study explores metabolic capabilities and activities of microorganisms involved in elemental cycling in hadal sediments, and reveals the different distribution of processes between its bottom-axis and slope. [ABSTRACT FROM AUTHOR]
Published: 2022
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23. Search for an excited lepton that decays via a contact interaction to a lepton and two jets in proton-proton collisions at √s = 13 TeV

Author: Tariq Aziz, Dave M Newbold, J. Seixas, Merve Ince, Manfred Paulini, Jessica Prisciandaro, Pierluigi Bortignon, N. Zaganidis, Etiennette Auffray, Fatma Boran, Daniel Pitzl, Ugo Gasparini, Veikko Karimäki, Maurizio Biasini, Cecilia Elena Gerber, Zaixin Wang, Elena Voevodina, Ioannis Papakrivopoulos, A. Yagil, Sinan Sagir, D. Domínguez Damiani, P. Das, Diego Beghin, Oleg Teryaev, I. Babounikau, A. Ranieri, Livia Soffi, R. B. Garg, Christopher Seez, Joaquin Emilo Siado, Laurent Thomas, Mark Derdzinski, Marta Felcini, Vasken Hagopian, G. M. Dallavalle, Ada Solano, Bhargav Madhusudan Joshi, Georgios Krintiras, Matteo Presilla, Zeynep Demiragli, Marina Kolosova, Victor Murzin, Maksat Haytmyradov, Paolo Montagna, EmineGurpinar Guler, Thomas Berger, Nikitas Loukas, J. Madhusudanan Sreekala, Othmane Bouhali, Q. Li, Milan Stojanovic, Carlos Erice, Katja Klein, H. Zhang, Marko Dragicevic, George Karathanasis, Y. Choi, Brandon Allen, Dustin Burns, Yalcin Guler, Roger Wolf, Marina Chadeeva, Lev Dudko, Jeremy Andrea, B. De La Cruz, Jose F Benitez, Samuel Higginbotham, Salvatore Costa, F. Mohamad Idris, Malte Backhaus, Vladimir Cherepanov, S. Choi, Stephen Sanders, Jens Multhaup, J. Puerta Pelayo, Indara Suarez, R. F. Harr, Ashish Sharma, Hasan Ogul, Joseph Heideman, Nicholas Wardle, David Mason, Luigi Moroni, Luca Lista, Marta Verweij, Hong Ni, W. T. Ford, P. J. Fernández Manteca, Tao Huang, Ajeeta Khatiwada, Mani Tripathi, Rachel Bartek, Marco Peruzzi, Usama Hussain, Owen Rosser Long, Warren Clarida, A. Escalante Del Valle, Dana Z. Anderson, Joosep Pata, Luca Guzzi, Colin Bernet, Maciej Górski, Andrea Malara, Isa Dumanoglu, Prabhat Ranjan Pujahari, Pierluigi Zotto, Hwi Dong Yoo, L. J. Sanchez Rosas, Urs Langenegger, Ugur Kiminsu, John Perry Cumalat, Swagata Mukherjee, Cesare Calabria, M. Csanad, Davide Zuolo, Markus Radziej, Roberto Mulargia, L. R. Sulak, M. A. Segura Delgado, Robert Bainbridge, Samandeep Sharma, Kristian Harder, Nicola Amapane, Andreas Nowack, Martti Raidal, Dylan Gilbert, Pamela Klabbers, Alessandro Caratelli, Natale Demaria, Thomas Bergauer, Michael Planer, Carlos Willmott, R. Del Burgo, Toni Sculac, Todor Ivanov, Inkyu Park, H. Wei, Koushik Mandal, H. El Mamouni, Yasser Assran, N. Turini, Vladimir Mossolov, David Krofcheck, J. P. Fernández Ramos, M. Ramirez-Garcia, Adrian Byszuk, Pritam Kalbhor, Vyacheslav Valuev, Michael Reichmann, Anton Babaev, Dennis Noll, Alberto Benvenuti, S. Gianì, Andrew Evans, Roberto Leonardi, Alexander Barnyakov, D. Cutts, W. Snoeys, Michael Benjamin Andrews, Simone Paoletti, Abhijith Gandrakota, Suchandra Dutta, Sertac Ozturk, J. A. Murillo Quijada, Giulio Mandorli, Ren-Yuan Zhu, Pascal Vanlaer, Richard Breedon, Anne-Marie Magnan, Wagner Carvalho, L. S. 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Bat, Vladimir Popov, Jacopo Pazzini, Peter Robmann, Elizabeth Starling, Nan Lu, René Caspart, Elisabetta Manca, Christoph Grab, Tiziano Camporesi, Brent Stone, Henning Kirschenmann, Stephane Perries, Costas Foudas, Louise Skinnari, Vito Palladino, Nural Akchurin, Hannu Siikonen, Devdatta Majumder, Frank Jensen, C. A. Salazar González, Dominique Gigi, Raffaello D'Alessandro, Marco Bozzo, Martina Malberti, S. Fonseca De Souza, Simone Pigazzini, Andrei Sobol, H. Bakhshiansohi, S. Slabospitskii, E. Eskut, Gabriella Pasztor, James Keaveney, Jay Dittmann, Pawan Kumar Netrakanti, Evgueni Tcherniaev, Constantin Heidegger, T. R. Fernandez Perez Tomei, Hao Qiu, K. A. Ulmer, Vitalii Okhotnikov, Petar Adzic, Maria Margherita Obertino, Alajos Makovec, Engin Eren, P. Van Mulders, Natasa Raicevic, Gianni Zumerle, Claudia Pistone, Michele Gallinaro, Alexey Golunov, P. H. 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Rebello Teles, Amandeep Kaur Kalsi, Leonard Spiegel, Francesco Romeo, Robert Klanner, Paolo Giacomelli, Andrea Benaglia, Darin Acosta, Kristian Allan Hahn, David J. Smith, Ministerio de Economía y Competitividad (España), European Commission, Principado de Asturias, European Research Council, SCOAP, CMS Collaboration, Damarseçkin, Serdal, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), CMS, Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Department of Physics, Helsinki Institute of Physics, Eija Tuominen / Principal Investigator, Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Karapınar, Güler, Izmir Institute of Technology. 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Subjects: excited state [muon], ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATION, Physics::Instrumentation and Detectors, 13000 GeV-cms, Hadron, Temel Bilimler (SCI), 7. Clean energy, 01 natural sciences, High Energy Physics - Experiment, mass spectrum, High Energy Physics - Experiment (hep-ex), Temel Parçacıklar ve Alanlar, Hadron-Hadron scattering (experiments), scattering [p p], [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ComputingMilieux_COMPUTERSANDEDUCATION, Invariant mass, Physics, 0105 Mathematical Physics, Large Hadron Collider, CMS, 4. Education, Temel Bilimler, Beyond Standard Model, Settore FIS/01 - Fisica Sperimentale, PHYSICS, PARTICLES & FIELDS, hadronic [jet], contact interaction, Beyond Standard Model, Hadron-Hadron scattering (experiments), e, Nuclear & Particles Physics, 3. Good health, CERN LHC Coll, Excited state, Physical Sciences, 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics, Natural Sciences (SCI), lower limit [mass], Physique des particules élémentaires, jet: pair production, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, PARTICLE PHYSICS, colliding beams [p p], HEAVY, Natural Sciences, associated production [lepton], branching ratio [lepton], Particle Physics - Experiment, lepton: associated production, High energy physics, Experimental particle physics, LHC, Particle Physics Experiments, Vector boson scattering, Supersymmetry, Higgs physics, Particle and resonance production, B physics, Particle correlations and fluctuations, Quarkonium, Elementary Particles and Fields, Jets, QCD, Top physics, Diboson, Electroweak, CKM matrix, Top quark, Large detector-systems performance, Pattern recognition, Nuclear and High Energy Physics, Particle physics, p p: scattering, muon: excited state, pair production [jet], lepton: excited state, mass: lower limit, FOS: Physical sciences, Fizik, 114 Physical sciences, decay modes, 0103 physical sciences, S054EXS, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, ddc:530, COMPOSITE MODELS, QUARKS, 010306 general physics, 0206 Quantum Physics, FİZİK, PARÇACIKLAR VE ALANLAR, S054MXS, Science & Technology, Muon, flavor, PP COLLISIONS, ComputingMilieux_THECOMPUTINGPROFESSION, hep-ex, 010308 nuclear & particles physics, Branching fraction, LARGE HADRON COLLIDER, lepton: branching ratio, High Energy Physics::Phenomenology, jet: hadronic, excited state [lepton], Basic Particles and Areas, Standard Model (mathematical formulation), lcsh:QC770-798, High Energy Physics::Experiment, p p: colliding beams, Lepton, experimental results
Abstract: The CMS collaboration: et al., Results are presented from a search for events containing an excited lepton (electron or muon) produced in association with an ordinary lepton of the same flavor and decaying to a lepton and two hadronic jets. Both the production and the decay of the excited leptons are assumed to occur via a contact interaction with a characteristic energy scale Λ. The branching fraction for the decay mode under study increases with the mass of the excited lepton and is the most sensitive channel for very heavy excited leptons. The analysis uses a sample of proton-proton collisions collected by the CMS experiment at the LHC at s√ = 13 TeV, corresponding to an integrated luminosity of 77.4 fb−1. The four-body invariant mass of the two lepton plus two jet system is used as the primary discriminating variable. No significant excess of events beyond the expectation for standard model processes is observed. Assuming that Λ is equal to the mass of the excited leptons, excited electrons and muons with masses below 5.6 and 5.7 TeV, respectively, are excluded at 95% confidence level. These are the best limits to date., Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l’Industrie et dans l’Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the “Excellence of Science — EOS” — be.h project n. 30820817; the Beijing Municipal Science & Technology Commission, No. Z191100007219010; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Deutsche Forschungsgemeinschaft (DFG) under Germany’s Excellence Strategy — EXC 2121 “Quantum Universe” — 390833306; the Lend¨ulet (“Momentum”) Program and the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research grants 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Science and Industrial Research, India; the HOMING PLUS program of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus program of the Ministry of Science and Higher Education, the National Science Center (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Education, grant no. 14.W03.31.0026 (Russia); the Programa Estatal de Fomento de la Investigacion Cientifica y Tecnica de Excelencia Maria de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programs cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Kavli Foundation; the Nvidia Corporation; the SuperMicro Corporation; the Welch Foundation, contract C-1845; and the Weston Havens Foundation (U.S.A.).
Published: 2020
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24. Investigation into the event-activity dependence of ϒ(nS) relative production in proton-proton collisions at s√ = 7 TeV

Author: Yacine Haddad, Gurpreet Singh Chahal, S. Sanchez Cruz, Andrew Buccilli, Charles C. Richardson, Antonin Kveton, Mauro Menichelli, Daniele Spiga, A. Da Rold, Luca Perniè, Roland Horisberger, J. Alexander, G. M. Bilei, David Jonathan Hofman, L. Viliani, Georgios Mavromanolakis, L. V. Kardapoltsev, Amitabh Lath, Simon Kudella, Troy Mulholland, Seungkyu Ha, S. Y. Hoh, F. L. Fabbri, Daniele Fasanella, Michele Arneodo, Garvita Agarwal, Elisa Manoni, Ka Tung Lau, S. Luo, D. Green, Brieuc Francois, A. Kasem, Shubham Pandey, Wei Shi, O. Rieger, Thomas Klijnsma, Thomas Madlener, Mikhail Gavrilenko, W. S. Hou, Nadezda Chernyavskaya, Juska Pekkanen, Ivan Ovtin, G. F. Chen, Christopher Rogan, Marek Gruchala, Sema Zahid, Rohith Saradhy, C. Martinez Rivero, Giorgio Apollinari, Ulf Behrens, M. A. Shah, Sergei Gleyzer, Ana Ovcharova, Marius Teroerde, B. Álvarez González, Georgia Karapostoli, I. R. Tomalin, M. Khakzad, Rino Castaldi, Benjamin Mesic, F. Pandolfi, A. Pérez-Calero Yzquierdo, Teruki Kamon, James Buchanan, Maxim Pieters, Nicolas Chanon, Helena Malbouisson, Davide Valsecchi, Maria Savina, J. D. Ruiz Alvarez, Brian Dorney, Mariarosaria D'Alfonso, Mario Galanti, Zoltan Szillasi, Jussi Viinikainen, A. Di Francesco, Ulrich Heintz, M. Kovac, Bjorn Burkle, N. Vanegas Arbelaez, Alex J. Barker, S. Lo Meo, Camelia Mironov, Valentina Avati, Giacomo Bruno, Ian Mcalister, Erhan Gülmez, Kaori Maeshima, Aurelijus Rinkevicius, Anton Petrov, Guido Tonelli, Zeljko Antunovic, Christoph Paus, Piergiulio Lenzi, Martin Erdmann, Cecilia Elena Gerber, Navid Rad, Rudy Ceccarelli, Andrew Wisecarver, Edoardo Bossini, Michele Bianco, Antoine Lesauvage, D. A. Sanz Becerra, J. A. Nash, Elisabetta Gallo, Vincenzo Ciriolo, Piotr Zalewski, Xinmei Niu, Benedikt Vormwald, Ilknur Hos, J. N. Butler, Dimitri Bourilkov, Patricia McBride, Krzysztof Doroba, Dylan Rankin, Andrew Brinkerhoff, S. W. Cho, Andrew Whitbeck, Viktor Veszpremi, Thomas Ferguson, Jose Flix, F. Rezaei Hosseinabadi, Andrey Uzunian, Christopher Palmer, Paolo Lariccia, Dmitry Sosnov, D. Domínguez Damiani, J. Park, Caleb Fangmeier, S. Cerci, Vinicius Massami Mikuni, P. Das, Diego Beghin, Yagya Raj Joshi, W. E. Johns, Mariana Shopova, Eric Christian Chabert, I. Heredia-De La Cruz, Tomas Kello, Dragos Velicanu, Qamar Hassan, Nuno Leonardo, A. Messineo, C-E Wulz, I. Babounikau, A. Ranieri, Livia Soffi, R. B. Garg, Christopher Seez, Susan Gascon, Ada Solano, Alice Bean, Gunther Roland, K. El Morabit, Balazs Ujvari, Ji Hwan Bhyun, Ketino Kaadze, Angelo Giacomo Zecchinelli, Chad Freer, Christian Contreras-Campana, E. W. Vaandering, Alexander Titterton, Adel Terkulov, Sandeep Bhowmik, Robin Aggleton, Ferhat Ozok, Andreas Nürnberg, Prasanna Siddireddy, Didier Contardo, Ashutosh Bhardwaj, O. Gonzalez Lopez, Olivér Surányi, Olena Karacheban, D. R. Mendis, Igor Vorobiev, Gregor Kasieczka, Martin Delcourt, I. Gonzalez Caballero, A. G. Stahl Leiton, Andrej Saibel, Salvatore My, Caglar Zorbilmez, P. C. Tiwari, Francesco Fallavollita, Shabnam Jabeen, T. Aushev, Thomas Reitenspiess, Jim Hanlon, D. Soldi, Stefan Piperov, Emrah Tiras, Toyoko Orimoto, Y. Chao, B. De La Cruz, Jose F Benitez, Samuel Higginbotham, Alexandre Zabi, V. Re, S. M. A. Ghiasi Shirazi, Andrius Juodagalvis, D. Abbaneo, T. A. Gómez Espinosa, Andrea Gozzelino, Kerstin Borras, T. Geralis, Mateusz Zarucki, Antoni Shtipliyski, Dong-Chul Son, Liliana Teodorescu, Kelly Beernaert, Bolek Wyslouch, P. Busson, Aaron Bundock, Katerina Lipka, Martin Kirakosyan, Georgios Bakas, F. Vazquez Valencia, Clément Leloup, Lata Panwar, Julie Managan Hogan, Jasvinder A. Singh, Panos A Razis, M. Rahmani, Dipanwita Dutta, Peter Raics, Peicho Petkov, Meena Meena, Alexei Safonov, A. Khan, Janos Erö, Michael Revering, Leonardo Cristella, Julia Velkovska, Sudha Ahuja, Halil Saka, Pietro Govoni, Gouranga Kole, Bruno Galinhas, V. K. Muraleedharan Nair Bindhu, Erik Brücken, William Tabb, Nicolaus Kratochwil, C. Neu, Ravi Janjam, Siddharth Narayanan, Patrick Jarry, J. D. Lewis, Benjamin Charles Radburn-Smith, Kevin Nash, Thea Klaeboe Aarrestad, Gourab Saha, Valentina Dutta, Illia Khvastunov, Lea Caminada, Rong-Shyang Lu, Lesya Shchutska, Andrea Massironi, Raffaella Radogna, Salvatore Costa, J. Puerta Pelayo, Indara Suarez, Erich Schmitz, Lutz Feld, Shervin Nourbakhsh, S. Belforte, Nabarun Dev, Johan Borg, Santeri Laurila, Kristian Harder, Kevin Mcdermott, Dmytro Kovalskyi, V. Kutzner, Gyorgy Vesztergombi, Ali Harb, Frank Jm Geurts, Maria Spiropulu, Christian Dorfer, John Gabriel Acosta, Anton Karneyeu, Leonard Apanasevich, M. Vander Donckt, Jochen Schieck, Thong Nguyen, James Dolen, Freya Blekman, Ilse Krätschmer, Vladimir Cherepanov, Shahram Rahatlou, E. Focardi, Pushpalatha C Bhat, Francesco Navarria, Sotiroulla Konstantinou, Devdatta Majumder, Maciej Górski, A. Bermúdez Martínez, Min Suk Kim, Achille Petrilli, Chun-Hua Jiang, G. Ortona, Smarajit Karmakar, T. W. Wang, David Michael Morse, L. Layer, G. Hamel de Monchenault, Aditee Rane, Antonio Cassese, Paul Lujan, Andrey Popov, Sushil Chauhan, Kajari Mazumdar, Nickolas Mccoll, Matthew Herndon, Elisa Fontanesi, Markus Stoye, Charalambos Nicolaou, Kai Yi, C. Wissing, A. Castaneda Hernandez, Niki Saoulidou, Vasilije Perovic, Vukasin Milosevic, Nikkie Deelen, Radia Redjimi, E. M. Da Costa, Simon Regnard, James H. Roberts, Jiajing Mao, P. G. Verdini, Christopher George Tully, Andrea Malara, Dave M Newbold, Sung Keun Park, Thomas James, Sercan Sen, D. P. Stickland, Nadir Daci, Sevgi Tekten, Prakash Thapa, Giovanni Abbiendi, Olmo Cerri, Olivier Davignon, Dmitri Konstantinov, Francisco Yumiceva, Ritva Kinnunen, Leonid Levchuk, Alexander Belyaev, H. S. Chen, Claudio Campagnari, Roberto Dell'Orso, J. W. Gary, Vipin Bhatnagar, T. Liu, Petar Maksimovic, Jan Tomsa, Thomas Bergauer, David Overton, Sang Il Pak, Arnaud Steen, D. Cutts, Thorsten Chwalek, S. Sánchez Navas, W. Snoeys, Michael Benjamin Andrews, Simone Paoletti, Jose Chinellato, K. F. Chen, R. Mankel, Wolfgang Lohmann, L. Silvestris, L. Malgeri, Kamuran Dilsiz, Jovan Milosevic, Aurélien Carle, Ulascan Sarica, Maria Toms, John Michael Marraffino, Geoffrey Smith, L. J. Gutay, Geng-Yuan Jeng, Seema Bahinipati, Boaz Klima, Pavel Parygin, J. S. Kim, Michael Tytgat, Carlos Willmott, R. Del Burgo, Vladimir Mossolov, Z. Zhang, Nadja Strobbe, Jean-Laurent Agram, Luca Scodellaro, Christos Roskas, Maria Cepeda, Irene Bachiller, Sergey Troshin, Filip Moortgat, Konstantinos Kousouris, Grace Cummings, Francesco Fienga, Apostolos Panagiotou, Benjamin Kilminster, Benjamin Fischer, Arne Reimers, Tejinder Virdee, Marcus Hohlmann, Mia Tosi, L. Romero, Abhijith Gandrakota, Prashant Shukla, Aniello Spiezia, S. Tkaczyk, David Stuart, Alice Mignerey, A. Benecke, Stefanos Leontsinis, A. Di Crescenzo, Jorgen D'Hondt, Daniela Schäfer, Davide Piccolo, T. Mitchell, Ivan Mikulec, Francesco Micheli, Gul Gokbulut, André Rosowsky, Andrew Ivanov, John Strologas, Suchandra Dutta, J. A. Murillo Quijada, Giulio Mandorli, Hasan Ogul, Don Upul Jayasiri Sonnadara, Anne-Marie Magnan, Wagner Carvalho, G. Paspalaki, Steven F. Maier, Anthony Moeller, John Perry Cumalat, Swagata Mukherjee, Savvas Kyriacou, Denis Rathjens, J. Fernandez Menendez, Charles Maguire, J. R. González Fernández, Chayanit Asawatangtrakuldee, David D'Enterria, C. Madrid, Christopher West, Jonas Roemer, Paolo Rumerio, Lorenzo Uplegger, Alexander Fröhlich, Joshua Bendavid, Nicanor Colino, Zhoudunming Tu, Isabel Ojalvo, Christian Autermann, Kenneth Bloom, David Lange, Robin Erbacher, Senta Greene, C. Baldenegro Barrera, Sherif Elgammal, Jennifer Chu, J. H. Kim, Thomas Perry, Dylan Teague, Natalia Emriskova, Youn Roh, Barry Blumenfeld, T. V. Dimova, Nicolò Tosi, S. Sarkar, M. Jones, Camilla Galloni, Seth Conrad Zenz, Sharad Malik, Carlos Florez, Andris Skuja, E. De La Cruz-Burelo, Helio Nogima, R. Tenchini, Roy Montalvo, W. H. Smith, Elif Asli Yetkin, Bahareh Roozbahani, Viktor Khristenko, Nadeesha Wickramage, Anna Zanetti, Q. Ingram, R. Sharma, Ilaria Vai, Kenneth Call, L. Valencia Palomo, Daniel Savoiu, Marko Dragicevic, J. M. Vizan Garcia, Bugra Bilin, Kati Lassila-Perini, Cesar Augusto Bernardes, P. E. Karchin, David Yu, Lalit Mohan Pant, Greg Landsberg, Cécile Caillol, Vladimir Epshteyn, Clemens Wöhrmann, A. Kumar, Vincenzo Daponte, Nicolas Postiau, P. D. Dauncey, A. Castro, Yuri Skovpen, A. Starodumov, Paul Avery, Salavat Abdullin, Lisa Benato, Ivica Puljak, L. I. Estevez Banos, Yeonju Go, A. Vagnerini, Daniel Marley, Quentin Python, Randy Ruchti, Joe Incandela, Kinga Anna Wozniak, Nicholas Manganelli, A. Di Mattia, Georgy Antchev, Manjit Kaur, S. Choi, Stephen Sanders, I. Dremin, P. De Castro Manzano, Xuejun Wang, Anthony Lefeld, Welathantri Gd Dharmaratna, Ioanna Papavergou, David Sperka, Gaelle Boudoul, Wolfgang Waltenberger, Alberto Orso Maria Iorio, Felice Pantaleo, Chanwook Hwang, Mário Costa, Hans Reithler, Ben Bylsma, Aaron Dominguez, Ivan Pozdnyakov, Ruchi Chudasama, Marco Rovere, G. Selvaggi, Christophe Ochando, Francesco Santanastasio, Stoyan Stoynev, A. Sanchez-Hernandez, Marco Musich, Hannsjoerg Artur Weber, Gordon H. Hanson, Rostyslav Shevchenko, Patrick Asenov, G. Ferri, M. Weber, Georg Auzinger, M. Aldaya Martin, Jindrich Lidrych, Vladimir Andreev, Fabio Cossutti, Joachim Mnich, Aruna Nayak, Harvey B Newman, Jeffrey Berryhill, Julia Thom, J. D. Tapia Takaki, J. H. Yoo, Finn Rebassoo, Melike Akbiyik, Rishika Bhardwaj, Simon Christoph Schuler, Niladribihari Sahoo, János Karancsi, Ali Celik, T. Boccali, Gervasio Gomez, Toni Sculac, Todor Ivanov, Apichart Hortiangtham, Dezso Horvath, A. De Cosa, Hannes Sakulin, T. Bose, Inkyu Park, Christina Reissel, Ryan Mueller, Joshua Hardenbrook, M. Ramirez-Garcia, Felicitas Pauss, Petra Merkel, Andreas Mussgiller, Valerio Bertacchi, Luca Cadamuro, Fotios Ptochos, Gobinda Majumder, V. Lemaitre, De Hua Zhu, S. Afanasiev, Alexis Kalogeropoulos, Tilman Rohe, Sara Nabili, H. Rejeb Sfar, Leonid Chtchipounov, M. Bluj, Riccardo Bellan, A. Álvarez Fernández, Yildiray Komurcu, J. L. Dulemba, Shuang-Nan Zhang, Tongguang Cheng, Sergo Jindariani, J. Schwandt, M. Ruspa, Jane Nachtman, Metin Yalvac, Stephan Lammel, Sergio F Novaes, Samet Lezki, Rachel Yohay, Hugo Delannoy, Daniel Noonan, C. Martin Perez, J. Rander, A. Escalante Del Valle, Joosep Pata, J. K. Lim, F. Simonetto, Suresh C Tonwar, Colin Bernet, Sylvie Braibant-Giacomelli, Jeffrey Roskes, Kalliopi Manitara, Sergio P Ratti, George Karathanasis, Y. Choi, Ferenc Sikler, Mauro Verzetti, Mario Kadastik, Alexander Dermenev, Minseok Oh, D. Sunar Cerci, Maciej Malawski, Brandon Allen, T. Aziz, Gaël Perrin, Dustin Burns, Anup Kumar Sikdar, Prabhat Ranjan Pujahari, Torben Dreyer, Q. Wang, Nikolay Tyurin, Caleb Smith, R. Kumar Verma, Narumon Suwonjandee, Frank Chlebana, Florian Michael Pitters, Si Xie, Kuntal Mondal, Giovanni Organtini, A. Delgado Peris, M. Fernandez, S. Somalwar, Pedrame Bargassa, Clément Grimault, A. Kayis Topaksu, H. A. Salazar Ibarguen, Umesh Joshi, Angira Rastogi, Claudio Grandi, Sébastien Gadrat, Christopher Mcginn, Doris Eckstein, Achim Geiser, Batoul Diab, Ivan Vila, S. Carrillo Moreno, Rohan Bhandari, Vinay Hegde, David Zou, Finn Feindt, J. S. H. Lee, Andrey Korytov, L. J. Sanchez Rosas, Daniel Robert Marlow, Haiyan Wang, Neeti Parashar, Roumyana Hadjiiska, Igor Smirnov, P. Chang, Eduardo De Moraes Gregores, Robert Stone, Ashfaq Ahmad, Xin Chen, Teresa Rodrigo, Austin Baty, Mayda Velasco, M. Melo De Almeida, Morgan Lethuillier, Yasar Onel, Alessia Saggio, Marco Toliman Lucchini, Mauricio Thiel, Ilya Gorbunov, P. Gras, Ashim Roy, Oliver Gutsche, A. Moraes, Tomas Lindén, Peter Timothy Cox, Torben Lange, Michael Mulhearn, Stephanie Kwan, Alexander Bylinkin, Th. Müller, Joachim Baechler, Ugur Kiminsu, G. P. Van Onsem, Raffaele Gerosa, Alexander Ledovskoy, Vincent J Smith, Meng Xiao, P. Janot, Amedeo Staiano, Martti Raidal, F. Vazzoler, Shameena Bonomally, Tai Sakuma, H. Van Haevermaet, Sam Harper, W. Ji, Simone Scarfi, Thoth Gunter, Laura Dodd, Andrew Levin, Kirti Ranjan, Anterpreet Kaur, Vytautas Dudenas, Anton Stepennov, Milos Dordevic, D. Kim, Daniel Teyssier, Kerstin Hoepfner, Carsten Hensel, Claudio Quaranta, Victor Perelygin, Manisha Lohan, M. M. Defranchis, Yutaro Iiyama, Mehmet Kaya, Intae Yu, Andrey Pozdnyakov, Lindsey Gray, Nikolay Voytishin, K. H. M. Kwok, Urs Langenegger, A. Venturi, Andrés G Delannoy, Christopher Hill, Andre Frankenthal, Kira Burt, M. A. Bhat, C. S. Moon, Jan Krolikowski, Luiz Mundim, S. Baur, Yves Sirois, Kun Shi, Adrian Byszuk, Pritam Kalbhor, Li Li, Alberto Belloni, Brian L Winer, R. Taus, Matteo Bonanomi, W. T. Hung, Piet Verwilligen, Klaus Rabbertz, Sebastiano Albergo, Isa Dumanoglu, Shuichi Kunori, Igor Lokhtin, J. Mejia Guisao, Ignacio Redondo, Benjamin Stieger, Y-J Lee, Cristina Biino, Limin Wang, Gabriele Benelli, Crisostomo Sciacca, Alexander Spiridonov, Shin-Shan Yu, Yurii Maravin, I. A. Melzer-Pellmann, Alessandra Fanfani, Patrizia Barria, Michelle C. Nguyen, J. Duarte Campderros, Frixos A Triantis, Andrew Askew, Vladimir Gavrilov, Francesca Nessi-Tedaldi, Yongho Jeong, Somnath Choudhury, Eleni Erodotou, R. D. Field, Jan Eysermans, Andreas Pfeiffer, Alessandra Cappati, Wenxing Fang, Geoffrey Hall, William Mcbrayer, Zachary Lesko, Kreso Kadija, Burin Asavapibhop, Xunwu Zuo, James Bueghly, H. Sert, Hongbo Liao, Aleko Khukhunaishvili, Stefano Marcellini, Sonaina Undleeb, Nicholas Menendez, M. Olmedo Negrete, Miao Hu, G. N. Kim, F. Mohamad Idris, Anna Elliott-Peisert, Vuko Brigljevic, Malte Backhaus, Attilio Santocchia, Georgios Tsipolitis, Sanjay Padhi, Jean Fay, M. H.L.S. Wang, Sourav Chatterjee, Alexander Morton, M. Alhusseini, John Alison, Aliakbar Ebrahimi, Andrew Mehta, David Taylor, B. Jayatilaka, Andrew Loeliger, Andrey Gribushin, Aran Garcia-Bellido, Markus Spanring, Nicholas Wardle, Debarati Roy, Jacobo Konigsberg, Ashley Parker, Furkan Dolek, Bryan Cardwell, N. De Filippis, Evgueni Vlasov, Javier Cuevas, D. H. Miller, Marc Dobson, Heiner Tholen, N. Van Remortel, Sarah Freed, Alicia Calderon, Alice Florent, Marcello Abbrescia, Siarhei Shulha, Seyed Mohsen Etesami, Tao Huang, Sandra Oliveros, Alfredo Gurrola, Maxim Goncharov, K. Ehataht, Ufuk Guney Tok, Christopher Brew, Gintautas Tamulaitis, Marco Pieri, Matti J Kortelainen, Umberto Dosselli, Günther Dissertori, Yi Chen, Teresa Lenz, Paolo Gunnellini, Lothar At Bauerdick, A. Colaleo, Cheng-Chieh Peng, M. Gola, J. Taylor, Laurent Mirabito, Steven Lowette, Christoph Garbers, Muhammad Ansar Iqbal, Ilya Kravchenko, Jeroen Hegeman, David Saltzberg, Andreas Werner Jung, Chandiprasad Kar, Fabio Iemmi, A. García Alonso, Anadi Canepa, P. Elmer, E. Ayala, Andres Tiko, G. P. Siroli, Alexei Raspereza, Dario Menasce, Wajid Ali Khan, Dong Ho Moon, Adam Elwood, Sami Lehti, Adish Vartak, Spandan Mondal, Valentina Mariani, A. C. Le Bihan, A. B. Meyer, Filippo Errico, Deepak Kumar Sahoo, Burak Bilki, Simranjit Singh Chhibra, Ali Eren Simsek, Eric Conte, David Barney, Aleksandra Lelek, B. Chazin Quero, Jack King, R. Vidal, Paraskevas Gianneios, Juliet Ritchie Patterson, V. Rodríguez Bouza, E. Gurpinar Guler, Pedro G Mercadante, Davide Zuolo, Riccardo Salvatico, Maurizio Pierini, David Cussans, Inna Kucher, Jelena Mijuskovic, Hyunyong Kim, Nicolò Trevisani, Gabriella Pugliese, Gianluca Cerminara, Kirill Skovpen, Alan Campbell, Lorenzo Russo, Biagio Rossi, Dener De Souza Lemos, Panagiotis Kokkas, Maria Teresa Grippo, Anatoli Zarubin, Kenneth Long, Andrea Carlo Marini, Alexander Tapper, Vyacheslav Krutelyov, R. E. Sosa Ricardo, Oliver Pooth, Leonardo Giannini, Christoph Heidecker, L. Ang, H. El Mamouni, Julie Malcles, Fengwangdong Zhang, A. Scribano, Kevin Lannon, Joao Varela, Prasant Kumar Rout, Leander Litov, Valerie Scheurer, Yi-ting Duh, Boris Grynyov, S. K. Pflitsch, Claudio Caputo, Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Stephanie Beauceron, Vladimir Palichik, Jean-Pierre Merlo, Caroline Elisabeth Niniane Niemeyer, Ulrich Husemann, A. Manousakis-Katsikakis, Fabio Monti, Tengizi Toriashvili, S. Bhattacharya, R. M. Brown, Giuseppe Barbagli, Matej Roguljic, Hannes Jung, Mark Saunders, Daniele Pedrini, Benedikt Maier, Rizki Syarif, Ia Iashvili, Roberto Seidita, Konrad Deiters, Guillaume Bourgatte, Jean-Roch Vlimant, Brajesh C Choudhary, Paul David Luckey, Jan Steggemann, Andrés Cabrera, P. Spagnolo, W. A. T. Wan Abdullah, Hans-Christian Kaestli, Jean-Louis Faure, Philipp Millet, Joanne Cole, Brian Francis, Federica Maria Simone, O. Zenaiev, James Wetzel, Jamal Rorie, Federica Legger, Tuure Tuuva, E. A. De Wolf, Alexander Zhokin, Martijn Mulders, Andreas Psallidas, C. Vander Velde, R. Bhattacharya, E. Carrera Jarrin, Douglas Wright, Sanjay Kumar, Danila Tlisov, Tamas Ferenc Csorgo, Paolo Checchia, Bhumika Kansal, John Almond, Andrea Triossi, Christoph Schwick, Richard Lander, Philippe Bloch, G. Della Ricca, Deborah Pinna, M. Maggi, Giacomo Fedi, Giles Strong, Marius Preuten, Nils Faltermann, Duong Nguyen, Niels Dupont, P. Van Hove, Alice Cocoros, Panagiotis Katsoulis, Zhengcheng Tao, Gy L. Bencze, Jason Gilmore, Marco Paganoni, Caterina Aruta, Shengquan Tuo, Jingzhou Zhao, Branislav Ristic, Vladyslav Danilov, Abhigyan Dasgupta, Zviad Tsamalaidze, Don Lincoln, Li Yuan, C. De Oliveira Martins, Martina Vit, Sh. Jain, J. M. Hernandez, Edward Laird, Aurore Savoy-Navarro, Guenakh Mitselmakher, Nikolai Skatchkov, A. K. Virdi, Eija Tuominen, Luca Mastrolorenzo, Laurent Forthomme, S. Orfanelli, M. Aguilar-Benitez, Patrick Connor, W. De Boer, Jory Sonneveld, Hafeez R Hoorani, J. Lykken, Pasquale Musella, Samuel Nathan Webb, Giovanni Mocellin, Yuta Takahashi, J. Vaitkus, V. Myronenko, Alessandro Cardini, Yangyang Cheng, Andrea Bocci, Daniel John Karmgard, M. Medina Jaime, Sébastien Viret, Margaret Zientek, Vieri Candelise, Lorenzo Bianchini, S. Seif El Nasr-storey, Unki Yang, Fanbo Meng, Caroline Collard, Simone Gennai, G. B. Mohanty, Kurtis F Johnson, Greg P Heath, Georgios Anagnostou, Melody A. Swartz, Maxwell Chertok, Manfred Jeitler, Danek Kotlinski, Jordan Martins, A. 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Di Croce, Denis Gelé, Catherine Schiber, Mauro Emanuele Dinardo, Carmen Albajar, Sven Dildick, Renato Campanini, Rosamaria Venditti, Daniel Abercrombie, A. Giassi, Pedro Silva, Ted Kolberg, W. J. Metzger, C. Uribe Estrada, Muhammad Shoaib, Marc Weinberg, Claude Charlot, Regina Demina, Reyer Band, Juliette Alimena, Paul Asmuss, E. J. Tonelli Manganote, Sourabh Dube, Marguerite Tonjes, Maksym Titov, Daniel Klein, Federico Ferri, Peter Hansen, Reddy Pratap Gandrajula, David Mark Raymond, E. O. Olaiya, Christophe Delaere, Marco Zanetti, U. Bhawandeep, Samuel Boren, Tobias Pook, Kisung Lee, Francisco Garcia, Basile Vermassen, Mohsen Naseri, Alain Givernaud, Seth Moortgat, Giorgia Rauco, Douglas Berry, Gabor Istvan Veres, Jay Hauser, A. Vilela Pereira, Bibhuprasad Mahakud, Nicola Minafra, Johannes Schulz, G. Gomez Ceballos, Nikos Varelas, Barbara Clerbaux, Irene Zoi, Pierluigi Paolucci, Carlos Lourenco, Nicholas Eminizer, Nhan Viet Tran, Cristina Tuve, R. G. 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Cooperstein, S, Deelen, N, Derdzinski, M, Duarte, J, Gerosa, R, Gilbert, D, Hashemi, B, Klein, D, Krutelyov, V, Letts, J, Masciovecchio, M, May, S, Padhi, S, Pieri, M, Sharma, V, Tadel, M, Würthwein, F, Yagil, A, Zevi Della Porta, G, Amin, N, Bhandari, R, Campagnari, C, Citron, M, Dutta, V, Incandela, J, Marsh, B, Mei, H, Ovcharova, A, Qu, H, Richman, J, Sarica, U, Stuart, D, Wang, S, Anderson, D, Bornheim, A, Cerri, O, Dutta, I, Lawhorn, J, Lu, N, Mao, J, Newman, H, Nguyen, T, Pata, J, Spiropulu, M, Vlimant, J, Xie, S, Zhang, Z, Zhu, R, Alison, J, Andrews, M, Ferguson, T, Mudholkar, T, Paulini, M, Sun, M, Vorobiev, I, Weinberg, M, Cumalat, J, Ford, W, Macdonald, E, Mulholland, T, Patel, R, Perloff, A, Stenson, K, Ulmer, K, Wagner, S, Alexander, J, Cheng, Y, Chu, J, Datta, A, Frankenthal, A, Mcdermott, K, Patterson, J, Quach, D, Ryd, A, Tan, S, Tao, Z, Thom, J, Wittich, P, Zientek, M, Abdullin, S, Albrow, M, Alyari, M, Apollinari, G, Apresyan, A, Apyan, A, Bauerdick, L, Beretvas, A, Berry, D, Berryhill, J, Bhat, P, Burkett, K, Butler, J, Canepa, A, Cerati, G, Cheung, H, Chlebana, F, Cremonesi, M, Elvira, V, Freeman, J, Gecse, Z, Gottschalk, E, Gray, L, Green, D, Grünendahl, S, Gutsche, O, Hanlon, J, Harris, R, Hasegawa, S, Heller, R, Hirschauer, J, Jayatilaka, B, Jindariani, S, Johnson, M, Joshi, U, Klijnsma, T, Klima, B, Kortelainen, M, Kreis, B, Lammel, S, Lewis, J, Lincoln, D, Lipton, R, Liu, M, Liu, T, Lykken, J, Maeshima, K, Marraffino, J, Mason, D, Mcbride, P, Merkel, P, Mrenna, S, Nahn, S, O’Dell, V, Papadimitriou, V, Pedro, K, Pena, C, Ravera, F, Reinsvold Hall, A, Ristori, L, Schneider, B, Sexton-Kennedy, E, Smith, N, Soha, A, Spalding, W, Spiegel, L, Stoynev, S, Strait, J, Taylor, L, Tkaczyk, S, Tran, N, Uplegger, L, Vaandering, E, Vidal, R, Wang, M, Weber, H, Woodard, A, Acosta, D, Avery, P, Bourilkov, D, Cadamuro, L, Cherepanov, V, Errico, F, Field, R, Guerrero, D, Joshi, B, Konigsberg, J, Korytov, A, Lo, K, Matchev, K, Menendez, N, Mitselmakher, G, Rosenzweig, D, Shi, K, Wang, J, Zuo, X, Joshi, Y, Adams, T, Askew, A, Habibullah, R, Hagopian, S, Hagopian, V, Johnson, K, Khurana, R, Kolberg, T, Martinez, G, Perry, T, Prosper, H, Schiber, C, Yohay, R, Zhang, J, Baarmand, M, Hohlmann, M, Noonan, D, Rahmani, M, Saunders, M, Yumiceva, F, Adams, M, Apanasevich, L, Betts, R, Cavanaugh, R, Chen, X, Dittmer, S, Evdokimov, O, Gerber, C, Hangal, D, Hofman, D, Kumar, V, Mills, C, Oh, G, Roy, T, Tonjes, M, Varelas, N, Viinikainen, J, Wang, H, Wang, X, Wu, Z, Alhusseini, M, Bilki, B, Dilsiz, K, Durgut, S, Gandrajula, R, Haytmyradov, M, Khristenko, V, Köseyan, O, Merlo, J, Mestvirishvili, A, Moeller, A, Nachtman, J, Ogul, H, Onel, Y, Ozok, F, Penzo, A, Snyder, C, Tiras, E, Wetzel, J, Yi, K, Blumenfeld, B, Cocoros, A, Eminizer, N, Gritsan, A, Hung, W, Kyriacou, S, Maksimovic, P, Mantilla, C, Roskes, J, Swartz, M, Vámi, T, Baldenegro Barrera, C, Baringer, P, Bean, A, Boren, S, Bylinkin, A, Isidori, T, Khalil, S, King, J, Krintiras, G, Kropivnitskaya, A, Lindsey, C, Mcbrayer, W, Minafra, N, Murray, M, Rogan, C, Royon, C, Sanders, S, Schmitz, E, Tapia Takaki, J, Williams, J, Wilson, G, Duric, S, Ivanov, A, Kaadze, K, Maravin, Y, Mendis, D, Mitchell, T, Modak, A, Mohammadi, A, Rebassoo, F, Wright, D, Baden, A, Baron, O, Belloni, A, Eno, S, Feng, Y, Hadley, N, Jabeen, S, Jeng, G, Kellogg, R, Mignerey, A, Nabili, S, Seidel, M, Skuja, A, Tonwar, S, Wang, L, Wong, K, Abercrombie, D, Allen, B, Bi, R, Brandt, S, Busza, W, Cali, I, D’Alfonso, M, Gomez Ceballos, G, Goncharov, M, Harris, P, Hsu, D, Hu, M, Klute, M, Kovalskyi, D, Luckey, P, Maier, B, Marini, A, Mcginn, C, Mironov, C, Narayanan, S, Niu, X, Paus, C, Rankin, D, Roland, C, Roland, G, Shi, Z, Stephans, G, Sumorok, K, Tatar, K, Velicanu, D, Wang, T, Wyslouch, B, Chatterjee, R, Evans, A, Guts, S, Hansen, P, Hiltbrand, J, Kubota, Y, Lesko, Z, Mans, J, Revering, M, Rusack, R, Saradhy, R, Schroeder, N, Strobbe, N, Wadud, M, Acosta, J, Oliveros, S, Bloom, K, Claes, D, Fangmeier, C, Finco, L, Golf, F, Kamalieddin, R, Kravchenko, I, Siado, J, Snow, G, Stieger, B, Tabb, W, Agarwal, G, Harrington, C, Iashvili, I, Kharchilava, A, Mclean, C, Nguyen, D, Parker, A, Pekkanen, J, Rappoccio, S, Roozbahani, B, Alverson, G, Barberis, E, Freer, C, Haddad, Y, Hortiangtham, A, Madigan, G, Marzocchi, B, Morse, D, Nguyen, V, Orimoto, T, Skinnari, L, Tishelman-Charny, A, Wamorkar, T, Wang, B, Wisecarver, A, Wood, D, Bueghly, J, Fedi, G, Gilbert, A, Gunter, T, Hahn, K, Odell, N, Schmitt, M, Sung, K, Velasco, M, Bucci, R, Dev, N, Goldouzian, R, Hildreth, M, Hurtado Anampa, K, Jessop, C, Karmgard, D, Lannon, K, Li, W, Loukas, N, Marinelli, N, Mcalister, I, Meng, F, Musienko, Y, Ruchti, R, Siddireddy, P, Smith, G, Taroni, S, Wayne, M, Wightman, A, Wolf, M, Alimena, J, Bylsma, B, Cardwell, B, Durkin, L, Francis, B, Hill, C, Ji, W, Lefeld, A, Ling, T, Winer, B, Dezoort, G, Elmer, P, Hardenbrook, J, Haubrich, N, Higginbotham, S, Kalogeropoulos, A, Kwan, S, Lange, D, Lucchini, M, Luo, J, Marlow, D, Mei, K, Ojalvo, I, Olsen, J, Palmer, C, Piroúe, P, Stickland, D, Tully, C, Norberg, S, Barker, A, Barnes, V, Chawla, R, Das, S, Gutay, L, Jones, M, Jung, A, Mahakud, B, Miller, D, Negro, G, Neumeister, N, Peng, C, Piperov, S, Qiu, H, Schulte, J, Trevisani, N, Wang, F, Xiao, R, Xie, W, Cheng, T, Dolen, J, Parashar, N, Baty, A, Behrens, U, Dildick, S, Ecklund, K, Freed, S, Geurts, F, Kilpatrick, M, Padley, B, Redjimi, R, Roberts, J, Rorie, J, Shi, W, Stahl Leiton, A, Tu, Z, Zhang, A, Bodek, A, de Barbaro, P, Demina, R, Dulemba, J, Fallon, C, Ferbel, T, Galanti, M, Garcia-Bellido, A, Hindrichs, O, Khukhunaishvili, A, Ranken, E, Taus, R, Chiarito, B, Chou, J, Gandrakota, A, Gershtein, Y, Halkiadakis, E, Hart, A, Heindl, M, Hughes, E, Kaplan, S, Laflotte, I, Lath, A, Montalvo, R, Nash, K, Osherson, M, Salur, S, Schnetzer, S, Somalwar, S, Stone, R, Thomas, S, Acharya, H, Delannoy, A, Spanier, S, Bouhali, O, Dalchenko, M, Delgado, A, Eusebi, R, Gilmore, J, Huang, T, Kamon, T, Luo, S, Malhotra, S, Marley, D, Mueller, R, Overton, D, Perniè, L, Rathjens, D, Safonov, A, Akchurin, N, Damgov, J, De Guio, F, Hegde, V, Kunori, S, Lamichhane, K, Mengke, T, Muthumuni, S, Peltola, T, Undleeb, S, Volobouev, I, Whitbeck, A, Greene, S, Gurrola, A, Janjam, R, Johns, W, Maguire, C, Melo, A, Ni, H, Padeken, K, Romeo, F, Sheldon, P, Tuo, S, Velkovska, J, Verweij, M, Ang, L, Arenton, M, Barria, P, Cox, B, Cummings, G, Hakala, J, Hirosky, R, Joyce, M, Ledovskoy, A, Neu, C, Tannenwald, B, Wolfe, E, Xia, F, Harr, R, Karchin, P, Poudyal, N, Sturdy, J, Thapa, P, Black, K, Bose, T, Buchanan, J, Caillol, C, Carlsmith, D, Dasu, S, De Bruyn, I, Dodd, L, Galloni, C, He, H, Herndon, M, Hervé, A, Hussain, U, Lanaro, A, Loeliger, A, Loveless, R, Madhusudanan Sreekala, J, Mallampalli, A, Pinna, D, Ruggles, T, Savin, A, Smith, W, Teague, D, Trembath-reichert, S, and Damarseçkin, Serdal
Subjects: ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATION, B physic, PBPB COLLISIONS, multiplicity [particle], Quarkonium, low [transverse momentum], Particle correlations and uctuations, Particle correlations and fluctuation, transverse momentum dependence, 01 natural sciences, B physics, High Energy Physics - Experiment, Physics, Particles & Fields, CROSS-SECTIONS, Hadron-Hadron scattering (experiments), scattering [p p], [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ComputingMilieux_COMPUTERSANDEDUCATION, Physic, ground state, Nuclear Experiment, differential cross section: ratio, Physics, underlying event, 0105 Mathematical Physics, CMS, Settore FIS/01 - Fisica Sperimentale, and fluctuations, multiplicity: dependence, Particle correlations, PP COLLISIONS, PARTICLE MULTIPLICITY, COLLECTIVITY, UPSILON(2S), STATE, LHC, Nuclear & Particles Physics, Experiment (hep-ex), charged particle, Particle correlations and fluctuations, Charged particle, muon: pair production, transverse, CERN LHC Coll, Excited state, 7000 GeV-cms, Physical Sciences, 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physique des particules élémentaires, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, PARTICLE PHYSICS, Ground state, sphericity, Particle Physics - Experiment, Nuclear and High Energy Physics, p p: scattering, High energy physics, Experimental particle physics, Particle Physics Experiments, Vector boson scattering, Supersymmetry, Higgs physics, Particle and resonance production, Meson, upsilon mesons: hadroproduction, transverse momentum: low, Astrophysics::High Energy Astrophysical Phenomena, education, meson, 114 Physical sciences, Sphericity, Nuclear physics, charged particle: multiplicity, muon, 0103 physical sciences, upsilon mesons: leptonic decay, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, ddc:530, High Energy Physics, Multiplicity (chemistry), 010306 general physics, 0206 Quantum Physics, Science & Technology, Muon, ComputingMilieux_THECOMPUTINGPROFESSION, hep-ex, 010308 nuclear & particles physics, LARGE HADRON COLLIDER, particle: multiplicity, Automatic Keywords, correlation, lcsh:QC770-798, High Energy Physics::Experiment, p p: colliding beams, experimental results
Abstract: The CMS collaboration: et al., The ratios of the production cross sections between the excited ϒ(2S) and ϒ(3S) mesons and the ϒ(1S) ground state, detected via their decay into two muons, are studied as a function of the number of charged particles in the event. The data are from proton-proton collisions at s√ = 7 TeV, corresponding to an integrated luminosity of 4.8 fb−1, collected with the CMS detector at the LHC. Evidence of a decrease in these ratios as a function of the particle multiplicity is observed, more pronounced at low transverse momentum pμμT. For ϒ(nS) mesons with pμμT > 7 GeV, where most of the data were collected, the correlation with multiplicity is studied as a function of the underlying event transverse sphericity and the number of particles in a cone around the ϒ(nS) direction. The ratios are found to be multiplicity independent for jet-like events. The mean pμμT values for the ϒ(nS) states as a function of particle multiplicity are also measured and found to grow more steeply as their mass increases., Individuals have received support from the Marie-Curie programme and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Leventis Foundation; the A.P. Sloan Foundation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l’Industrie et dans l’Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the F.R.S.-FNRS and FWO (Belgium) under the “Excellence of Science — EOS” — be.h project n. 30820817; the Beijing Municipal Science & Technology Commission, No. Z191100007219010; the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Deutsche Forschungsgemeinschaft (DFG) under Germany’s Excellence Strategy — EXC 2121 “Quantum Universe” — 390833306; the Lend¨ulet (“Momentum”) Programme and the J´anos Bolyai Research Scholarship of the Hungarian Academy of Sciences, the New National Excellence Program UNKP, the NKFIA research grants 123842, 123959, 124845, 124850, 125105, 128713, 128786, and 129058 (Hungary); the Council of Science and Industrial Research India; the HOMING PLUS programme of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus programme of the Ministry of Science and Higher Education, the National Science Center (Poland), contracts Harmonia 2014/14/M/ST2/00428, Opus 2014/13/B/ST2/02543, 2014/15/B/ST2/03998, and 2015/19/B/ST2/02861, Sonata-bis 2012/07/E/ST2/01406; the National Priorities Research Program by Qatar National Research Fund; the Ministry of Science and Higher Education, project no. 02.a03.21.0005 (Russia); the Programa Estatal de Fomento de la Investigacion Cientifica y ´ecnica de Excelencia Mar´ıa de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias; the Thalis and Aristeia programmes cofinanced by EU-ESF and the Greek NSRF; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); the Kavli Foundation; the Nvidia Corporation; the SuperMicro Corporation; the Welch Foundation, contract C-1845; and the Weston Havens Foundation (U.S.A.)., Article funded by SCOAP3.
Published: 2020
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25. Responsive Polymeric Nanoparticles for Biofilm-infection Control.

Author: Su, Lin-Zhu, Liu, Yong, Li, Yuan-Feng, An, Ying-Li, and Shi, Lin-Qi
Subjects: MULTIDRUG resistance, BIOFILMS, NANOPARTICLES, MULTIDRUG resistance in bacteria, BACTERIAL diseases, TRANSLATING & interpreting
Abstract: With the emergence of multidrug resistance (MDR) in many pathogens, bacterial infections are becoming a growing threat to public health. The frightening scenario is due largely to the formation of biofilms, in which the bacteria are extremely recalcitrant to the conventional antibiotic regimens. To address the emergence of MDR and biofilm-associated infections, numerous polymer-based materials have been designed and prepared recently. The subject of this perspective is the recent development of polymer-based materials that have been applied to combat multidrug-resistant pathogens, to prevent the formation of biofilms, or enhance the eradication efficacy to mature biofilms via killing biofilm-bacteria or dispersing biofilms. The advantages and shortcomings of these polymer-based materials are discussed, as well as the challenges we are facing in the clinical translation of these systems. [ABSTRACT FROM AUTHOR]
Published: 2021
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26. Correlations of Serological Markers with Development of Systemic Involvement in Adult Immunoglobulin A Vasculitis: A Retrospective Study of 259 Patients in Central China.

Author: Nie, Ying-li, Song, Ze-xing, Tao, Juan, Han, Xu, and Yang, Liu
Published: 2021
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27. Study on the regulatory effect of herbal cake-partitioned moxibustion on colonic CD206, AMPK and TSC2 in rats with Crohn disease.

Author: Xiao-qing, Dong, Xiao-ying, Li, Xue-jun, Wang, Xiao-cong, Guo, Jun-yi, Long, Yun-qiong, Lu, Li, Liu, Jia-ni, Caoyao, Dan, Zhang, Yuan, Lu, Huan-gan, Wu, Chen, Xie, and Xiao-peng, Ma
Abstract: Copyright of Journal of Acupuncture & Tuina Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Published: 2021
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28. A Cocrystal of Baicalein and 4,4′-Bipyridine with Zipper-Type Architecture.

Author: Liu, Li-xin, Su, Xin, Zhang, Yu-nan, Yin, He-mei, Zhang, Qiang, Feng, Yan-ru, Guo, Ying-xue, Zou, Dong-yu, and Liu, Ying-li
Subjects: HYDROGEN bonding, SOLUBILITY, SURFACE analysis, SOLVENTS
Abstract: A new cocrystal of baicalein, possessing three A-ring-hydroxyl groups and without B-ring-hydroxyl groups and 4,4′-bipyridine (BE·2BPY·H2O) has been prepared and characterized. The structural analyses and Hirshfeld surfaces show that baicalein is hydrogen-bonded to co-crystallized solvent water molecules featuring for example motifs that can be described with graph set R44(8) similar to those reported for the cocrystal of myricetin with 4,4′-bipyridine. A zipper-type architecture is observed in cocrystal BE·2BPY·H2O linking a baicalein, two 4,4′-bipyridine and a solvent water molecules via classical O–H⋯N and O–H⋯O and non-classical C–H⋯O hydrogen bonds into 2D sheets. Additionally, the cocrystal shows better solubility in 0.1 M HCl in comparison to pure baicalein. Cocrystal of baicalein with zipper-type architecture shows improved solubility compared to baicalein. [ABSTRACT FROM AUTHOR]
Published: 2021
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29. Calculation method of the contact stiffness of bed-foundation interfaces considering foundation creep.

Author: Yongsheng, Zhao, Nana, Niu, Hongyan, Chu, Ying, Li, Kai, Jiang, and Lingjun, Meng
Published: 2021
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30. Fe3O4@Angelica sinensis polysaccharide nanoparticles as an ultralow-toxicity contrast agent for magnetic resonance imaging.

Author: Wang, Kai, Xu, Xiao-Guang, Ma, Ying-Li, Sheng, Chun-Rui, Li, Li-Na, Lu, Li-Ying, Wang, Jian, Wang, Yi-Ning, and Jiang, Yong
Abstract: Although iron oxide (Fe3O4) nanoparticles have broad application prospects as magnetic resonance imaging (MRI) contrast agent, their biocompatibility and biotoxicity still need to be improved. In this study, we prepared Fe3O4@Angelica sinensis polysaccharide nanoparticles (Fe3O4@ASP NPs) with a 9 nm Fe3O4 core and ASP as the coating material. The Fe3O4@ASP NPs are superparamagnetic, can be taken up by liver and spleen macrophages in the circulatory system in vivo, and are a good-biocompatibility and low-toxicity transverse relaxation time (T2) and T2-star (T2*) magnetic resonance imaging (MRI) contrast agent for the liver. The cytotoxicity assessment using HeLa cells and the pathological tests in mice validate that Fe3O4@ASP NPs have low toxicity and good biocompatibility in vivo, which can be attributed to the ASP as a natural polysaccharide with good biocompatibility and its function of protecting the liver. Fe3O4@ASP NPs are a potential new MRI contrast agent with high signal intensity in vivo. [ABSTRACT FROM AUTHOR]
Published: 2021
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31. Microstructure and mechanical properties of friction-stir-welded high-Mg-alloyed Al–Mg alloy plates at different rotating rates.

Author: Li, Ying-Li, Xia, Wei-Jun, Yan, Hong-Ge, Chen, Ji-Hua, Ding, Tian, Sun, You-Ping, and Li, Xin-Yu
Abstract: Hot-rolled high-Mg-alloyed Al–Mg alloy (Al–9.2Mg–0.8Mn–0.2Zr–0.15Ti, labeled as 5A12) plates were successfully friction stir welded at rotating rates ranging from 750 to 1500 r·min−1 at a constant welding speed of 50 mm·min−1. The joints were characterized by optical microscopy (OM), electron backscatter diffraction (EBSD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), electron-dispersive spectroscopy (EDS), and tensile testing. All the joints are volume defect-free and exhibit fine, equiaxed dynamic recrystallization (DRX) grains with high-angle grain boundaries (HAGBs) fractions of 88.6%–93.3% in the nugget zones (NZs). The DRX grain size and the second-phase particle size in the NZs have a parabolic relation with the rotating rate. Furthermore, among the joints tested, the joint prepared at 1000 r·min−1, which has the highest ultimate tensile strength ((478 ± 3) MPa) and the largest elongation to rupture (22.5% ± 1.4%)—approximately 87.5% and 145.2% those of the base metal, respectively, exhibits the smallest grain size of 2.93 μm, as well as the smallest particle size in the NZs. These excellent mechanical properties can be ascribed to the combined effects of the fine DRX grains with high fraction of HAGBs and the fine second-phase particles with a uniform distribution. [ABSTRACT FROM AUTHOR]
Published: 2021
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32. Inertial optimization MCL deep mine localization algorithm based on grey prediction and artificial bee colony.

Author: Xiuwu, Yu, Ying, Li, Yong, Liu, and Hao, Yu
Subjects: *MONTE Carlo method, *BEES algorithm, *PROBLEM solving, *ALGORITHMS
Abstract: To solve the problem that the existing Monte Carlo Localization (MCL) algorithm has long localization time and large localization error in the real-time localization of downhole personnel and mobile equipment, an inertial optimization MCL deep mine localization algorithm based on gray prediction and artificial bee colony (IMCL-GABC) is proposed. Firstly, the movement speed and direction of the personnel or equipment to be located at the current moment are estimated by the grey prediction model, and the sampling area is determined by combining with the structural characteristics of the deep mine roadway. Secondly, the artificial bee colony algorithm is introduced to optimize the filtering to eliminate the less likely position points and obtain the approximate optimal estimated position sampling set. Finally, the weight of the sample is optimized by motion inertia, so as to complete the localization of the personnel or mobile equipment to be located. The simulation results show that the average localization error of the IMCL-GABC algorithm is 0.46 m and the average localization time required for the node to move one step is 0.21 s. Compared with the other two mobile node localization algorithms MCL and Monte Carlo localization Boxed, the localization error of IMCL-GABC algorithm is reduced by 50% and 37.84% respectively, and the localization time is reduced by 4.6 s and 0.93 s respectively, which proves that IMCL-GABC algorithm effectively improves the localization accuracy and efficiency of downhole personnel and mobile equipment. [ABSTRACT FROM AUTHOR]
Published: 2021
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33. Genome analysis of Salmonella phage vB_SalM_8-19 (genus Rosemountvirus).

Author: Cong, Cong, Bing Dong, Wei, Hui Jing, Cui, Yu Yu, Yuan, Yong Ping, Xu, Li Li, Wang, Shu Ying, Li, Ji Bin, Li, Mu, Xu, and Xiao Yu, Li
Subjects: SALMONELLA, GENES, SWINE farms, GENOMES, SALMONELLA enterica, TRANSFER RNA, BACTERIOPHAGES
Abstract: This work describes the characterization and genome annotation of Salmonella phage vB_SalM_8-19 (referred to as 8-19) isolated from sewage samples collected in a pig farm in Jilin, China. This phage was capable of infecting 60% Salmonella strains in our lab stock. The genome of phage 8-19 is composed of linear double-stranded DNA that is 52,648 bp in length with a G + C content of 46.02%; containing 74 ORFs and no tRNA genes. In October 2019, phylogenetic analyses indicated that phage 8-19 might belong to a novel cluster among the other similar phages which have not been specifically classified within some new genus in family Myoviridae. Recently, the International Committee on Taxonomy of Viruses (ICTV) defined phage 8-19 and its related phages as genus Rosemountvirus, family Myoviridae. This new genus, known as Rosemountvirus, is rarely reported in the literature. [ABSTRACT FROM AUTHOR]
Published: 2021
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34. Two Transition Metal Complexes: Magnetic Properties and Treatment Effect via Focused High-Intensity Ultrasound on Alzheimer's Disease.

Author: Huo, Chang-Lu, Yu, Ting, Pei, Cai-Ying, Liu, Ling-Ling, Zhang, Ying-Rui, and Zhang, Ying-Li
Abstract: Two novel coordination polymers (where Cu for the complex 1 and the Co for the complex 2) with distinct transition metal ions containing 4-(3,5-dicarboxylphenyl)-2-methylpyridine (H2L), the pyridyl-dicarboxylic acid ligand, have been produced under the solvothermal reaction conditions, and the two compounds' performances and architectures were also characterized. The chemical formulae determined of two complexes are respectively [Cu(L)(H2O)]·H2O (1) and [Co3(L)2Cl2(H2O)2]·2H2O (2). Complex 1 exhibits a 2D network with a (3,6)-connected kgd topology based on the dinuclear [Cu2O2] units. In complex 2, the linear trinuclear [Co3(μ-Ocarboxylate)2(COO)2Cl2] units with mixed carboxylate and μ-Cl triple bridges are cross-linked by the L ligands into a 3D framework with a (3,6)-connected rtl topology. The complexes' magnetic performances reflected that between consecutive metal ions, there exists the antiferromagnetic coupling. Their treatment activities on Alzheimer's disease (AD) via focused high-intensity ultrasound were evaluated. Firstly, the Annexin V-fluorescein isothiocyanate/propidium iodide staining was implemented for the assessment of the apoptotic neurons percentage after compounds treatment. Next, the Aβ accumulation in the neurons was also detected via employing the western blotting assay. [ABSTRACT FROM AUTHOR]
Published: 2021
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35. Photoluminescence study of the In0.3Ga0.7As surface quantum dots coupling structure.

Author: Yang, Ying-li, Liu, Zeng-guang, Wang, Guo-dong, Wang, Ying, Yuan, Qing, and Fu, Guang-sheng
Abstract: Photoluminescence (PL) was investigated as functions of the excitation intensity and temperature for a coupling surface quantum dots (SQDs) structure which consists of one In0.3Ga0.7As SQDs layer being stacked on multi-layers of In0.3Ga0.7As buried quantum dots (BQDs). Accompanied by considering the localized excitons effect induced by interface fluctuation, carrier transition between BQDs and SQDs were analyzed carefully. The PL measurements confirm that there is a strong carrier transition from BQDs to SQDs and this transition leads to obvious different PL characteristics between BQDs and SQDs. These results are useful for future application of SQDs as surface sensitive sensors. [ABSTRACT FROM AUTHOR]
Published: 2021
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36. Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.

Author: He, Qing-Tao, Xiao, Peng, Huang, Shen-Ming, Jia, Ying-Li, Zhu, Zhong-Liang, Lin, Jing-Yu, Yang, Fan, Tao, Xiao-Na, Zhao, Ru-Jia, Gao, Feng-Yuan, Niu, Xiao-Gang, Xiao, Kun-Hong, Wang, Jiangyun, Jin, Changwen, Sun, Jin-Peng, and Yu, Xiao
Subjects: ARRESTINS, G protein coupled receptors, GENETIC code, PHOSPHORYLATION, PHOSPHOPEPTIDES, SPECTRUM analysis
Abstract: Arrestins recognize different receptor phosphorylation patterns and convert this information to selective arrestin functions to expand the functional diversity of the G protein-coupled receptor (GPCR) superfamilies. However, the principles governing arrestin-phospho-receptor interactions, as well as the contribution of each single phospho-interaction to selective arrestin structural and functional states, are undefined. Here, we determined the crystal structures of arrestin2 in complex with four different phosphopeptides derived from the vasopressin receptor-2 (V2R) C-tail. A comparison of these four crystal structures with previously solved Arrestin2 structures demonstrated that a single phospho-interaction change results in measurable conformational changes at remote sites in the complex. This conformational bias introduced by specific phosphorylation patterns was further inspected by FRET and 1H NMR spectrum analysis facilitated via genetic code expansion. Moreover, an interdependent phospho-binding mechanism of phospho-receptor-arrestin interactions between different phospho-interaction sites was unexpectedly revealed. Taken together, our results provide evidence showing that phospho-interaction changes at different arrestin sites can elicit changes in affinity and structural states at remote sites, which correlate with selective arrestin functions. The interaction between a GPCR, such as the vasopressin receptor-2 (V2R), and arrestin depends on the receptors' phosphorylation pattern. Here authors use FRET and NMR to analyze the phosphorylation patterns of the V2R-arrestin complex and show that phospho-interactions are the key determinants of selective arrestin conformational states and correlated functions. [ABSTRACT FROM AUTHOR]
Published: 2021
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37. Molecular dynamics and in silico mutagenesis on the reversible inhibitor-bound SARS-CoV-2 main protease complexes reveal the role of lateral pocket in enhancing the ligand affinity.

Author: Weng, Ying Li, Naik, Shiv Rakesh, Dingelstad, Nadia, Lugo, Miguel R., Kalyaanamoorthy, Subha, and Ganesan, Aravindhan
Subjects: *MUTAGENESIS, *MOLECULAR dynamics, *COVID-19, *LIGANDS (Biochemistry), *PROTEOLYTIC enzymes
Abstract: The 2019 novel coronavirus pandemic caused by SARS-CoV-2 remains a serious health threat to humans and there is an urgent need to develop therapeutics against this deadly virus. Recent scientific evidences have suggested that the main protease (Mpro) enzyme in SARS-CoV-2 can be an ideal drug target due to its crucial role in the viral replication and transcription processes. Therefore, there are ongoing research efforts to identify drug candidates against SARS-CoV-2 Mpro that resulted in hundreds of X-ray crystal structures of ligand-bound Mpro complexes in the Protein Data Bank (PDB) describing the interactions of different fragment chemotypes within different sites of the Mpro. In this work, we performed rigorous molecular dynamics (MD) simulation of 62 reversible ligand–Mpro complexes in the PDB to gain mechanistic insights about their interactions at the atomic level. Using a total of over 3 µs long MD trajectories, we characterized different pockets in the apo Mpro structure, and analyzed the dynamic interactions and binding affinity of ligands within those pockets. Our results identified the key residues that stabilize the ligands in the catalytic sites and other pockets of Mpro. Our analyses unraveled the role of a lateral pocket in the catalytic site in Mpro that is critical for enhancing the ligand binding to the enzyme. We also highlighted the important contribution from HIS163 in the lateral pocket towards ligand binding and affinity against Mpro through computational mutation analyses. Further, we revealed the effects of explicit water molecules and Mpro dimerization in the ligand association with the target. Thus, comprehensive molecular-level insights gained from this work can be useful to identify or design potent small molecule inhibitors against SARS-CoV-2 Mpro. [ABSTRACT FROM AUTHOR]
Published: 2021
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38. Revealing the Common Mechanisms of Scutellarin in Angina Pectoris and Ischemic Stroke Treatment via a Network Pharmacology Approach.

Author: Meng, Zi-qi, Wu, Jia-rui, Zhu, Ying-li, Zhou, Wei, Fu, Chang-geng, Liu, Xin-kui, Liu, Shu-yu, Ni, Meng-wei, and Guo, Si-yu
Subjects: LIPID metabolism, ANGINA pectoris, CARRIER proteins, CELLULAR signal transduction, FLAVONOIDS, MEDICINAL plants, PHARMACOLOGY, PROTEINS, STROKE, TUMOR necrosis factors, PLANT extracts, MITOGEN-activated protein kinases, SIGNAL peptides, MOLECULAR docking
Abstract: Objective: To investigate the shared mechanisms of scutellarin in angina pectoris (AP) and ischemic stroke (IS) treatment. Methods: A network pharmacology approach was used to detect the potential mechanisms of scutellarin in AP and IS treatment by target prediction, protein-protein interaction (PPI) data collection, network construction, network analysis, and enrichment analysis. Furthermore, molecular docking simulation was employed to analyze the interaction between scutellarin and core targets. Results: Two networks were established, including a disease-target network and a PPI network of scutellarin targets against AP and IS. Network analysis showed that 14 targets, namely, AKT1, VEGFA, JUN, ALB, MTOR, ESR1, MAPK8, HSP90AA1, NOS3, SERPINE1, FGA, F2, FOXO3, and STAT1, might be the therapeutic targets of scutellarin in AP and IS. Among them, NOS3 and F2 were recognized as the core targets. Additionally, molecular docking simulation confifirmed that scutellarin exhibited a relatively high potential for binding to the active sites of NOS3 and F2. Furthermore, enrichment analysis indicated that scutellarin might exert a therapeutic role in both AP and IS by regulating several important pathways, such as coagulation cascades, mitogen-activated protein kinase (MAPK) signaling pathway, phosphatidylinositol 3 kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway, Toll-like receptor signaling pathway, hypoxia inducible factor-1 (HIF-1) signaling pathway, forkhead box O (FoxO) signaling pathway, tumor necrosis factor (TNF) signaling pathway, adipocytokine signaling pathway, insulin signaling pathway, insulin resistance, and estrogen signaling pathway. Conclusions: The shared underlying mechanisms of scutellarin on AP and IS treatment might be strongly associated with its vasorelaxant, anticoagulant, anti-inflammatory, and antioxidative effects as well as its effect on improving lipid metabolism. [ABSTRACT FROM AUTHOR]
Published: 2021
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39. Generalized stability of Heisenberg coefficients.

Author: Ying, Li
Subjects: *REPRESENTATION theory, *LOGICAL prediction
Abstract: Stembridge introduced the notion of stability for Kronecker triples, which generalizes Murnaghan's classical stability result for Kronecker coefficients. Sam and Snowden proved a conjecture of Stembridge concerning stable Kronecker triples, and they also showed an analogous result for Littlewood–Richardson coefficients. Heisenberg coefficients are Schur structure constants of the Heisenberg product which generalize both Littlewood–Richardson coefficients and Kronecker coefficients. We show that any stable triple for Kronecker coefficients or Littlewood–Richardson coefficients also stabilizes Heisenberg coefficients, and we classify the triples stabilizing Heisenberg coefficients. We also follow Vallejo's idea of using matrix additivity to generate Heisenberg stable triples. [ABSTRACT FROM AUTHOR]
Published: 2020
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40. Refractive Index Engineering as a Novel Strategy toward Highly Transparent and Tough Sustainable Polymer Blends.

Author: Sun, Si-Ting, Wang, Hang, Huang, Dong, Ding, Ying-Li, Zhang, Yang, Song, Dong-Po, Zhang, Kun-Yu, Pan, Li, and Li, Yue-Sheng
Subjects: POLYMER blends, REFRACTIVE index, IMPACT strength, MOIETIES (Chemistry), IONOMERS, ELASTOMERS
Abstract: High transparency and toughness are prerequisites for sustainable polymers if they are to find wide application as alternatives to petroleum-based polymers. However, the utility of sustainable polymers such as commercially available polylactide (PLA) is limited by their inherent brittleness and high cost. Unfortunately, toughening PLA-based materials via cost-effective blending strategies without sacrificing transparency remains a challenge. Herein, we report a novel strategy involving active refractive index matching for creation of highly transparent and tough PLA blends. Specifically, we engineered the refractive index of a promising renewable poly(epichlorohydrin-co-ethylene oxide) elastomer by introducing polar ionic moieties via a simple chemical method, and we blended the resulting ionomers with PLA. The best blend showed an impact strength of > 80 kJ/m2, an elongation at break of 400%, and high transparency (90%). These characteristics are of great importance for potential applications such as packaging. Our strategy offers a versatile new way to prepare high-performance sustainable polymer materials with excellent transparency. [ABSTRACT FROM AUTHOR]
Published: 2020
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41. Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.

Author: Qiao, Chen-Meng, Sun, Meng-Fei, Jia, Xue-Bing, Li, Yang, Zhang, Bo-Ping, Zhao, Li-Ping, Shi, Yun, Zhou, Zhi-Lan, Zhu, Ying-Li, Cui, Chun, and Shen, Yan-Qin
Subjects: SODIUM butyrate, BUTYRATES, PARKINSON'S disease, ASTROCYTES, DOPAMINE, INFLAMMATION, DOPAMINERGIC neurons, TYROSINE hydroxylase, MICE
Abstract: The abnormal production of short chain fatty acid (SCFAs) caused by gut microbial dysbiosis plays an important role in the pathogenesis and progression of Parkinson's disease (PD). This study sought to evaluate how butyrate, one of SCFAs, affect the pathology in a subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (MPTP) treated mouse model of PD. Sodium butyrate (NaB; 165 mg/kg/day i.g., 7 days) was administrated from the day after the last MPTP injection. Interestingly, NaB significantly aggravated MPTP-induced motor dysfunction (P < 0.01), decreased dopamine (P < 0.05) and 5-HT (P < 0.05) levels, exacerbated declines of dopaminergic neurons (34%, P < 0.05) and downregulated expression of tyrosine hydroxylase (TH, 47%, P < 0.05), potentiated glia-mediated neuroinflammation by increasing the number of microglia (17%, P < 0.05) and activating astrocytes (28%, P < 0.01). In vitro study also confirmed that NaB could significantly exacerbate pro-inflammatory cytokines expression (IL-1β, 4.11-fold, P < 0.01; IL-18, 3.42-fold, P < 0.01 and iNOS, 2.52-fold, P < 0.05) and NO production (1.55-fold, P < 0.001) in LPS-stimulated BV2 cells. In addition, NaB upregulated the expression of pro-inflammatory cytokines (IL-6, 3.52-fold, P < 0.05; IL-18, 1.72-fold, P < 0.001) and NLRP3 (3.11-fold, P < 0.001) in the colon of PD mice. However, NaB had no effect on NFκB, MyD88 and TNF-α expression in PD mice. Our results indicate that NaB exacerbates MPTP-induced PD by aggravating neuroinflammation and colonic inflammation independently of the NFκB/MyD88/TNF-α signaling pathway. [ABSTRACT FROM AUTHOR]
Published: 2020
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42. First case of Shewanella indica isolated from a Bryde's whale (Balaenoptera edeni) stranded in the northern Beibu Gulf, China.

Author: Li, Jia, McLaughlin, Richard W., Chen, Mo, Liu, Ying Li, Xie, Hia Xia, Wan, Xiao Ling, Zhou, Jun Ying, and Zheng, Jin Song
Abstract: The purpose of this study was to culture and characterise bacteria from an intact abscess on the skin of a dead Bryde's whale (Balaenoptera edeni) which stranded in the northern Beibu Gulf, China. To grow bacteria, samples from the abscess were added to blood agar. After incubation, yellowish mucous colonies were visualized. The bacterium was firstly recognised as Shewanella algae by the VITEK® 2 System. However, by using 16S rRNA gene sequencing the bacterium was finally identified as S. indica. To characterise the bacterium, antibiotic susceptibility and virulence factors, such as hemolysis and biofilm formation were investigated. The bacterium is capable of β-hemolysis and biofilm formation and it is also sensitive to several different classes of antibiotics, such as β-lactams, quinolones, and aminoglycosides. To date there have been no reports of this bacterium causing infections in humans or animals. However, in this study we described the first case of S. indica isolated from an intact abscess on the back of a Bryde's whale. [ABSTRACT FROM AUTHOR]
Published: 2020
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43. An empirical study on energy utilization efficiency, economic development, and sustainable management.

Author: Pan, Xin-Xin, Chen, Mei-Lan, Ying, Li-Meng, and Zhang, Fang-Fang
Subjects: ENERGY consumption, ECONOMIC development, ECONOMIC activity, PRICE fluctuations, KUZNETS curve
Abstract: Based on the premise of sustainable development of the environment, how to achieve the balance of energy utilization, economic development, and sustainable management of the environment is becoming increasingly important in the process of stable economic development. This paper analyzes the concept of environmental Kuznets curve, taking 35 European countries as the research objects, first discusses the trend of energy utilization efficiency from 1990 to 2013, and then analyzes the relationship between energy efficiency and economic development. Empirical results show that labor has a significant negative impact on energy efficiency and the increase in labor input will reduce energy efficiency. If the added value of national manufacturing accounts for a higher percentage in GDP, it will have a negative impact on the effectiveness of energy utilization. In addition, when the national price level is high, price fluctuation will increase the price of energy utilization, or the cost of energy input in economic activities, which will further reduce the country's energy efficiency performance. Lastly, the empirical study also found that energy efficiency and economic development showed a quadratic U-shaped relationship, indicating that the long-term energy efficiency of the country will first decline and then rise during economic activities. [ABSTRACT FROM AUTHOR]
Published: 2020
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44. Relationship between Free Thyroxine and Islet Beta-cell Function in Euthyroid Subjects.

Author: Li, Qing, Lu, Meng, Wang, Ning-jian, Chen, Yi, Chen, Ying-chao, Han, Bing, Li, Qin, Xia, Fang-zhen, Jiang, Bo-ren, Zhai, Hua-ling, Lin, Dong-ping, and Lu, Ying-li
Published: 2020
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45. Effect of intercritical deformation on tensile performance of a low-carbon Si–Mn steel processed by quenching and bainitic partitioning.

Author: Tian, Ya-qiang, Cao, Zhong-qian, Li, Wang, Pan, Hong-bo, Zheng, Xiao-ping, Song, Jin-ying, Wei, Ying-li, and Chen, Lian-sheng
Published: 2020
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46. Systems-Based Interactome Analysis for Hematopoiesis Effect of Angelicae sinensis Radix: Regulated Network of Cell Proliferation towards Hemopoiesis.

Author: Zheng, Guang, Zhang, He, Yang, Yun, Sun, Ying-li, Zhang, Yan-jing, Chen, Ju-ping, Hao, Ting, Lu, Cheng, Guo, Hong-tao, Zhang, Ge, Fan, Dan-ping, He, Xiao-juan, and Lu, Ai-ping
Subjects: CELL proliferation, ANEMIA, BACTERIAL growth, BONE marrow, HEMATOPOIESIS, HERBAL medicine, INTERLEUKIN-2, CHINESE medicine, MICROBIOLOGICAL techniques, MOLECULAR biology, MOLECULAR structure, PROTEIN-tyrosine kinases, SPLEEN, WORKFLOW, JANUS kinases
Abstract: Objective: To explore the molecular-level mechanism on the hematopoiesis effect of Angelicae sinensis Radix (ASR) with systems-based interactome analysis. Methods: This systems-based interactome analysis was designed to enforce the workflow of "ASR (herb)→compound→target protein→internal protein actions→ending regulated protein for hematopoiesis". This workflow was deployed with restrictions on regulated proteins expresses in bone marrow and anemia disease and futher validated with experiments. Results: The hematopoiesis mechanism of ASR might be accomplished through regulating pathways of cell proliferation towards hemopoiesis with cross-talking agents of spleen tyrosine kinase (SYK), Janus kinase 2 (JAK2), and interleukin-2-inducible T-cell kinase (ITK). The hematopoietic function of ASR was also validated by colony-forming assay performed on mice bone marrow cells. As a result, SYK, JAK2 and ITK were activated. Conclusion: This study provides a new approach to systematically study and predict the therapeutic mechanism for ASR based on interactome analysis towards biological process with experimental validations. [ABSTRACT FROM AUTHOR]
Published: 2019
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47. Gender Stereotyping by Location, Female Director Appointments and Financial Performance.

Author: Compton, Ying Li, Kang, Sok-Hyon, and Zhu, Zinan
Subjects: GENDER stereotypes, WOMEN directors of corporations, BOARDS of directors, INDUSTRIAL location, FINANCIAL performance
Abstract: We investigate whether female board representation and firms' financial performance are related and whether the relationship differs for firms located in more prejudicial environments. As a proxy for prejudicial environment, we use two geographical indicators: (1) whether a firm is headquartered in a conservative "red" state (which tends to vote for Republican candidates) or in a liberal "blue" state (which tends to vote for Democratic candidates) and (2) whether the firm is located in regions where residents possess more stereotypical attitudes about gender equality. We find that both financial performance and female board representation are lower for firms headquartered in red states when compared to those in blue states, and we find similar results for firms located in regions where residents hold more gender-stereotypical views. However, financial performance improves when female directors are present regardless of the firm's location. Evidence also shows that the incremental improvement in performance measured by Tobin's q is greater in red-state than in blue-state companies and in regions where residents hold more gender-stereotypical views. The overall results imply that gender stereotyping holds back financial performance and that female directors help improve financial performance. [ABSTRACT FROM AUTHOR]
Published: 2019
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48. Correction to: The effects of job characteristics on physicians' orientation toward lifelong learning.

Author: Lin, Ying-Li, Chen, Huey-Ling, Chen, Yen-Yuan, Cheng, Shao-Yi, Chen, Wei-Li, Chiu, Yu-Chun, and Chiu, Yen-Lin
Subjects: PHYSICIANS' attitudes, MEDICAL education
Published: 2023
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49. Estimations of Three Characteristic Stress Ratios for Rockfill Material Considering Particle Breakage.

Author: Guo, Wan-Li, Cai, Zheng-Yin, Wu, Ying-Li, and Geng, Zhi-Zhou
Published: 2019
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50. Ectopic thyroids have lower computed tomography attenuation values than orthotopic thyroids.

Author: Gu, Ting, Lu, Ying-li, Han, Bing, Jiang, Bo-Ren, Wang, Li-Zhen, Yang, Li-Zhen, and Han, Yong-Shun
Abstract: Purpose: To determine whether ectopic thyroid had the same computed tomography (CT) value as orthotopic thyroid.Methods: Twenty-one patients with 23 ectopic thyroids and 23 controls with orthotopic thyroids underwent CT scans and were included in this retrospective study. The CT images were reviewed in a blinded fashion by two radiologists. Independent-Samples T-test was used for comparison of CT attenuation values between two groups.Results: Ectopic thyroids had significantly lower non-enhanced attenuation (91.04 ± 5.97 Hounsfield Units vs. 106.56 ± 4.06 Hounsfield Units, P = 0.038) and contrast-enhanced attenuation (141.32 ± 6.42 Hounsfield Units vs. 169.82 ± 4.30 Hounsfield Units, P = 0.001) values than orthotopic thyroids.Conclusions: Ectopic thyroids have lower CT attenuation values than orthotopic thyroids probably due to the structural or functional abnormalities. The dysgenesis and pathological changes of the ectopic thyroids may contribute to functional deficiency which finally leads to decrease of the CT attenuation values. [ABSTRACT FROM AUTHOR]
Published: 2018
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