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In order to further explore the soil consolidation effect of vegetation roots, to explore the best vegetation slope protection model. Based on the existing research results of vegetation slope protection, the use of numerical simulation method was discussed to simulate the hydrological effect and mechanical mechanism of vegetation roots. The effects of root slope protection under the conditions of simulating different slopes, rainfall, root inclination, root length, root density and root distribution were summarized. According to the displacement and stress field of the slope, or by comparing the stability coefficient of the slope and the shear strength of the root soil under different conditions, the slope protection effect of the root system can be more accurately reflected, and the applicability of the numerical simulation method can be further verified. Numerical simulation can consider multiple influencing factors and analyze the role of vegetation root slope protection. In the future, the root system model needs to be continuously improved and more comprehensive factors should be considered in the application of root slope protection. [ABSTRACT FROM AUTHOR]

The separation and recovery of N，N-dimethylformamide (DMF) from the liquid containing high mass fraction of DMF is studied by continuous extraction in a pulsed disc and doughnut extraction column (PDDC), which combines with a distillation process. For the feed liquid with 38. 46% DMF, chloroform is used as the extraction agent and DMF is extracted in a PDDC. The effects of the extraction operation parameters such as oil-water ratio, flow rate and pulse conditions on the DMF extraction are studied. The results show that the extraction efficiency of DMF increases with the addition of pulsation, the increase of oil-water ratio and the increase of two phase flow rate. Under the optimized conditions, the highest extraction ratio of DMF ias 99. 94%, and the DMF mass fraction in raffinate is less than 0. 5%. Furthermore, batch distillation experiments and simulation calculations are carried out for the separation of chloroform solution loaded with DMF. The results show that effective separation and recovery of chloroform and DMF can be achieved through continuous distillation. [ABSTRACT FROM AUTHOR]

Aiming at improving the driving safety problems caused by the functional deterioration of the original pavement surface or early diseases when the pavement structure diseases are not prominent and the strength is sufficient, the post blending process is applied to study the ultra-thin cover of skeleton dense SMA-10 warm mix epoxy asphalt. Through a series of tests, the mechanical properties, water stability, crack resistance, sliding durability and interlayer bonding properties were systematically evaluated. The results show that the ultra-thin cover of warm mixed epoxy asphalt has stable and good mechanical properties and serviceability; Basalt fiber has significantly improved its crack resistance. Compared with wood fiber, its bending tensile strain, impact toughness and crack resistance index have increased by 16.7%, 93.9% and 130.4% respectively; Epoxy asphalt mixture has better skid resistance and durability than SBS modified asphalt, which can significantly improve the rapid decline of asphalt pavement functionality; At the same time, epoxy asphalt as binder, its bonding performance is significantly better than matrix asphalt and SBS modified asphalt, and it is suggested that the amount of binder material should be reasonably reduced in high-temperature areas. [ABSTRACT FROM AUTHOR]

Educational modernization is the integral part and important foundation of Chinese-style modernization, and it is the basic and strategic support to realize Chinese-style modernization. To realize the modernization of China's education, elementary education teaching staff is the key force. In the new era, the state has introduced a series of systematically integrated policies for the elementary education teachers and improved the system of teacher work and the system of teacher management, the system of teacher education with Chinese characteristics has been established and strengthened, the problem of the number and scale of teachers has been historically solved, the status and treatment of teachers have been continuously improved, and the weak points in the construction of the teaching staff have been quickly filled up, the social atmosphere of respecting teachers and valuing education has continued to be strong, and the overall vitality of the teaching staff has been fully released. In the future, we should continue to improve the new pattern of the construction of the trinity of elementary education teaching staff, promote the balanced allocation of high-quality teachers, empowering and enhancing the efficiency of the teaching staff in the new era. [ABSTRACT FROM AUTHOR]

Measuring and feeding back on the implementation effects of China’ s domestic waste classification policies is of great significance to the formulation and improvement of these policies. From the front-end perspective of an individual’ s knowledge, attitude, and behavior, the policy effect of the compulsory classification of domestic waste in China is intuitive, sustainable, and implementable. This research focused on the support willingness and execution willingness of urban residents to the policy of compulsory classification of domestic waste. Compiling a special emotional dictionary for the policy of compulsory classification of domestic waste and using text mining and sentiment analysis, we obtained the attitudes of Shanghai residents who were the first to implement this policy in China. Based on the synthetic control method, a number of cities that had not implemented this policy were selected as the control group for fitting, to simulate the situation in Shanghai where the policy was not implemented and to compare with the effect of the current compulsory classification policy to highlight the implementation effects of the compulsory policy. Finally, we used the data of each city to conduct a robustness test in time and region to prove the reliability of the conclusions obtained. The results of the study showed that, since the proposal for compulsory waste classification in China, although the support and execution willingness of urban residents had fluctuated, the overall trend was upward, and the execution willingness was generally lower than the support willingness. The policy of compulsory classification of domestic waste significantly increased the support and execution willingness of Shanghai residents, although its level of practice was still relatively low. The quality and size of the population played a negative role in the moderating effect of the policy effects, weakening the promotion effect of the policy on residents’ support and execution willingness. Finally, corresponding policy recommendations are put forward based on the analysis results. [ABSTRACT FROM AUTHOR]

Objective: To study the effect of lipoprotein lipase (LPL) gene knockout on lung injury in mice with cerulein-induced hyperlipidemia and acute pancreatitis. Methods: C57BL/6 mice were divided into three groups. The Control group and the AP-Model group were wild-type C57 BL/6 mice, and the LPL ko group was the LPL knockout C57 BL/6 mice; the Control group was fed normally, and the AP-Model and A hyperlipidemia acute pancreatitis model was established in the LPL ko group of mice, and the mortality, pancreatic and lung pathological damage, and serum amylase (AMY), malondialdehyde (MDA), tumor necrosis and tumor necrosis levels were compared among the three groups. Factor-α(Tumor necrosis factor-α, TNF-α) and interleukin-6 (Interleukin-6, IL-6) content. Results: 48 hours after the establishment of acute pancreatitis, the mortality rates of mice in the Control group, AP-Model group and LPL ko group were 0%, 20% and 40%, respectively. Compared with the control group, the pancreas and lung tissue wet/dry weight ratios, pancreas and lung histopathological scores, serum AMY, MDA, TNF-αand The content of IL-6 was significantly increased (P<0.05); compared with the AP-Model group, the pancreas and lung tissue wet/dry weight ratio, pancreas and lung tissue pathology of LPL ko group mice 24 and 48 hours after the induction of acute pancreatitis Scores, serum AMY, MDA, TNF-αand IL-6 levels were significantly increased (P<0. 05). Conclusion: LPL knockout mice had more severe acute hyperlipidemic pancreatitis lung injury, and the mechanism may be related to the stronger oxidative stress and inflammation induced by LPL knockout. [ABSTRACT FROM AUTHOR]

Natural fiber is a sustainable bio-renewable resource, which can improve the overall road performance of asphalt mixture, especially the anti-cracking and anti-fatigue performance. It delays the early disease of asphalt pavement and has good application prospect. The article introduces the characteristics of natural fibers and the performance enhancement mechanism of fiber asphalt mixtures, reviews the latest research results of natural organic plant fibers and inorganic mineral fibers in asphalt mixtures. In the future, the research and application of plant fibers such as waste fibers and non-wood fibers in pavement should be strengthened, and the problems of compatibility, hydrophilicity and thermal stability of plant fibers should be explored from the surface modification of fibers; in addition, basalt fiber is a high-performance natural inorganic mineral fiber, and its enhancement mechanism and effect on asphalt concrete performance should be studied from the aspects of composite modification, and the research on ceramic fiber or other non-polluting mineral fiber should be strengthened to broaden the choice of polluting high-performance fibers for road, to promote the development of high-performance asphalt mixtures and achieve long life of asphalt pavement. [ABSTRACT FROM AUTHOR]

Objective :Natural gas measurement management is an important certificate to ensure the normal development of natural gas trade and transfer, and it has a great influence on the economic benefits of both natural gas buyers and sellers. It is difficult to find the abnormal positioning of measurement equipment data in real time in practical applications, which leads to accumulated errors in measurement data and may cause large economic losses. measurement management personnel urgently need practical tools to solve this problem. Methods Based on the investigation and analysis of the abnormal data sources of the metering equipment, this paper establishes an abnormal data diagnosis indicator system, and based on the real-time monitoring of system data, a newtype of measurement remote diagnosis system has been developed. Results The remote diagnosis system realizes real-time on-line measurement diagnosis. The system issues a diagnostic report to guide on-site maintenance. Conclusions Using this new metering remote diagnosis system saves the time and cost of metering personnel's on-site travel and troubleshooting, and escorts the stable operation of pipelines. [ABSTRACT FROM AUTHOR]

Aiming at the problems of complex color matching process,low production efficiency and large material consumption of traditional manual color spun yarn,a color matching algorithm of color spinning based on improved Stearns-Noechel model was proposed to improve the color matching accuracy. The minimum fitting color difference in the original color matching is changed to the minimum reflectivity deviation as the selection basis of variable constant M value,and the formula corresponding to M value is used as the best fitting formula. The results showed that the formula calculated by the improved color matching algorithm was closer to the actual formula and had higher accuracy. The range of color difference before and after improvement is below 1,but it is significantly lower after improvement,indicating that the improved color matching calculation method was more applicable. Reset [ABSTRACT FROM AUTHOR]

[Objective] By quantifying the apparent characteristic values of tobacco leaves at different time periods, the change law of tobacco water content was mastered, and the water content of tobacco leaves at different time periods was predicted according to the nonlinear characteristics of time series data of flue-cured tobacco water content and the strong correlation between flue-cured tobacco water content at adjacent periods. [Method] Image information technology was used to extract and analyze color of tobacco leaves [lightness value (L), red degrees (a), yellow (b), saturation degree value (C) and hue Angle (H) J and texture characteristic [ texture feature mean (m), standard deviation (er), smoothness (R), three moments (fL3), consistency (U) and texture entropy (e) J. Six apparent factors [lightness values (L) red degree value (a) yellow degree (b) texture means (m) standard (er) and entropy (e) texture J from principal component analysis were used as sample sets of network model. Kolmogorov theorem and test method were used to determine the prediction model for 13 hidden layer nodes. L-M (Levenberg-Marquardt) training algorithm used training fitting of limited time, to establish the topological structure of BP neural network model for the 6-13 -1 and predict water content of tobacco leaf. [Result] The changes of tobacco leaf image color features and texture features of the value were in accord with the tobacco leaf apparent reflect changes in baking process. This indicated that tobacco leaf image information conformed to the neural network input layer and output layer correlation model. The tobacco moisture content of the BP neural network prediction model (the determination coefficient R2 was 0. 9987 and RMSE root mean square error was 0. 0118) could well predict the moisture content of tobacco leaf in the different periods. [Conclusion] Therefore, the different periods of model of BP neural network model for predicting water in the tobacco leaf could be used to master dynamic change law of the moisture content of tobacco leaf. [ABSTRACT FROM AUTHOR]

Regarding the impacts of failures among elevator components, a combination model based on decision-making trial and evaluation laboratory (DEMATEL) and interpretation structural model (ISM) was proposed to establish the hierarchical model for elevator component failure. The method of determining the direct impact matrix was enhanced. Firstly, the evaluation of the elevator-component fault correlation was obtained from various aspects. Secondly, the entropy weight method (EWM) was used to determine the weight of the evaluation and calculate the direct impact matrix. Finally, the elevator-component failure correlation model was utilized to derive the elevator-component failure causality and failure transmission rules. The results show that the motor, brake and speed limiter are strong-cause components, while the traction rope, car and guidance system components are strong-effect components. The elevator-component failure correlation rules manifest as either same-level or cross-level transmission. Through an analysis of component failure mechanisms, the fault transfer rules obtained through the proposed method align with the actual operation of the elevator system. [ABSTRACT FROM AUTHOR]

In order to systematically understand the measurement methods of carbon⁃14（14C）in environmental and biological samples, clarify the possible advantages and disadvantages of various methods. Based on the comparison of domestic measurement methods, this paper made an in⁃depth exploration of the 14C measurement method system, and systematically analyzed the precipitation method, bubbling method, high temperature combustion oxidation method, wet oxidation method, oxidative combustion method and oxygen bomb combustion method on sample pretreatment;powder suspension method, direct absorption method, benzene synthesis method and graphite method on sample preparation;liquid scintillation counting method and accelerator mass spectrometry on sample measurement methods, this paper analyzes the problems existing in different methods and proposes solutions, hoping to deepen the understanding of analytical methods for laboratory technicians and improve the 14C measurement level in environmental and biological samples in China. [ABSTRACT FROM AUTHOR]

Mechanical harvesting safflower has increased rapidly, with the continuous expansion of planting areas in recent years. However, the branch swing of safflower generally interferes with accurate visual recognition positioning and harvesting quality in selective harvesting of safflower. In this study, a strip-collected pre-positioning mechanism was proposed for a picking robot to adjust the morphology of safflower plants before visual recognition. The key factors were clarified on the swing of branches during harvesting, according to the growth characteristics of safflower, including the single safflower, the high growth center of the top of the fruit ball, the different opening time, and symmetrical distribution of spatial morphology of safflower plants. A safflower plant strip-collected mechanism also ran with the trunk position recognition to explore the plant shape for the pre-positioned state of strip-collected. The key working parts were designed to determine the structural parameters of safflower plant strip-collected and trunk position recognition mechanism. Specific works included: 1) A kind of safflower plant club mechanism was designed to meet the requirements of strip-collected operation, according to the four-bar kinematics. The key parameters were also optimized for the strip-collected trajectory drive mechanism and clamping plate. 2) The cam motion was utilized to determine the key parameters of trunk position recognition. The position relationship between the strip-collected operation and each working section of the cam was further analyzed to match the working stroke of strip-collected operation and the trunk position recognition. 3) A field test showed that the qualified rate of exposed length of anti swing branch was 80.53%, the fruit ratio of safflower fruit ball was 2.04%, the damage rate of plant was 0.47%, the damage rate of fruit ball was 1.04%, the width-to-width ratio was 16.64%, the dispersion of fruit ball was 83.76%, and the shading rate of fruit ball was 6.51%. Consequently, the strip-collected pre-positioning operation can effectively reduce the swing of the branches, where the whole safflower fruit balls are orderly distributed, and finally reduce the difficulty of identification and picking of the whole safflower. This finding can provide a sound theoretical basis for automatic safflower picking in modern mechanical harvesting. [ABSTRACT FROM AUTHOR]

Objective: To explore the efficacy and safety of self expanding stent assisted coil embolization in the treatment of intracranial aneurysms. Methods: From January 2014 to January 2019,159 patients with intracranial aneurysms were treated with self expanding stent assisted coil embolization (group A) and 178 patients with intracranial aneurysms (group B) were treated with simple coil embolization. The operative time, postoperative hospital stay, follow-up time and complications of the two methods were compared, and the safety and efficacy of the two methods were compared by Glasgow(GOS) prognosis score and Raymond score. Results: There was no significant difference in operation time, postoperative hospitalization time and follow-up time between the two groups (P>0.05). There was significant difference in the incidence of postoperative bleeding and ischemic events between the two groups (P<0.05), but there was no significant difference in the incidence of hydrocephalus, pneumonia, mortality and disability between the two groups(P=1 after continuous correction). The GOS score of group A was higher than that of group B within 1 month and 12 months after operation, the difference was statistically significant (P<0.05); the Raymond grade of group A was better than that of group B within 1 month and 12 months after operation, the difference was statistically significant (P<0.05). Conclusion: Self expanding stent assisted coil embolization is effective for intracranial aneurysm embolization and has few postoperative complications. For patients with intracranial aneurysms, self expanding stent assisted coil embolization can improve the safety of operation and the efficacy of embolization. [ABSTRACT FROM AUTHOR]

In response to teaching painful points, team teachers guided by ideological and political education and utilized modern information technology as the medium, optimize course objectives, reconstruct teaching content, and reshape teaching process. Meanwhile, team teachers strengthen interactive debates, improve evaluation mechanisms and explore a teaching innovation path of "three convergences, four prominences ". It comprehensively addresses the "pain points" of the course, strives to create an outstanding course with "two genders and one degree", and promotes the enhancement of students' innovation ability and comprehensive qualities. [ABSTRACT FROM AUTHOR]

Taking the self-compacting concrete pouring of steel shell immersed tubes in Shenzhen-Zhongshan Channel as the research background, the workability of the self-compacting concrete mix ratio was verified by the single-bin scale model test, and the location and cause of the defects during the concrete pouring were grasped. The ratio of defect area and volume, the maximum / average defect depth, the main defect distribution and other parameters of the top surface of the concrete pouring were tested by using two-level grayscale processing method and the stone powder filling method, the larger defects are often concentrated near the blanking opening and the back of the top stiffener, which provides data support for the subsequent construction of the steel shell immersed tube self-compacting concrete. [ABSTRACT FROM AUTHOR]

【Objective】The present paper aimed to explore the research hotspots of mining wasteland reclamation and ecological restoration and analyze its trend.【Method】 Based on Web of Science core aggregate database as the data source, the research literature in the field of mining wasteland reclamation and ecological restoration from 2009 to 2019 was taken as the object of study. Based on the technology of text information visualization and Citespace, this paper introduced the latest research achievements and progress of mining wasteland reclamation and ecological restoration at home and abroad by establishing the relationship maps of cooperation characteristics and cooccurrence analysis through annual volume of papers, countries, institutions and authors. By using the methods of clustering cited documents and keyword co-occurrence analysis, this paper analyzed the research hotspots from the perspectives of scientific and technological text mining and bibliometrics, and summarized the development trend of this field in the past 10 years through the analysis of keyword co-occurrence. 【Result】 In recent years, the number of papers on mining wasteland increased year by year, more than doubling in 10 years. China’s research in the field of mining wasteland reclamation and ecological restoration was at a relatively advanced level. The contribution rate and centrality of the research papers were the first and third research fields, which were gradually becoming disciplinary, institutionalized and systematized, and tending to be perfect. Reclamation and land reclamation were the most frequent occurrences. The frequency of land, forest and climate change has increased significantly, which has gradually formed a new branch of research. 【Conclusion】 The research of mining wasteland reclamation and ecological restoration could be divided into two stages. From 2009 to 2015, the main focus was on the physical field, mainly from different land cover changes, accumulation density and plant population, etc. From 2016 to 2019, the main focus was on mining engineering, and related research was carried out on mining activities and the impact of mining wasteland on the surrounding areas. The research results can provide references for the development of mining wasteland reclamation and ecological restoration and the improvement of scientific research system. [ABSTRACT FROM AUTHOR]

Objective To explore the practical effect of the newly continuous nursing mode constructed for patients with enterostomy. Methods With holistic care as the core concept, Omaha system as the theoretical framework, demand level theory and the forgetting curve principle as the reference basis, the model of continuous care for patients with intestinal stoma was established from five aspects : continuous care team, follow up form, follow up frequency, nursing content and nursing process. 128 cases patients who underwent enterostomy for colorectal cancer in the hospital from April to December 2017 were selected as the study subjects and randomly divided into the experimental group (n = 63) and the control group (n=65) through the random number table method. The experimental group implemented the extended care model established above, and the control group received routine discharge care. After 6 months of intervention, the practice effect was analyzed by means of cognitive behavior status (KBS) score, stomatal adaptability, stomatal self care ability, stomatal complication rate and discharge nursing satisfaction. Results The KBS scores of the experimental group before and after the intervention showed statistically significant differences (P < 0.05), and the stomatal adaptability and self care ability were significantly improved compared with those before the intervention (t = -16. 217, 29.287, P< 0.05). In the experimental group, the stoma adaptability, stoma self care ability and nursing service satisfaction were significantly higher than those in the control group, and the incidence of stoma complications was significantly lower than that in the control group, with statistically significant differences ( t = - 9.753, 6.648, - 9.357,X'= 12.098,P<0. 05). Conclusion The continuous nursing model constructed is scientific and practical, which effectively improves the health status of patients with enterostomy, reduces the incidence of complications, improves the stoma adaptability and self care ability, and improves the satisfaction of nursing. [ABSTRACT FROM AUTHOR]

Objective To observe the effect of Astragalus polysaccharide ( APS) on intestinal damage in obstructive jaundice (OJ) rats and to explore its possible mechanism. Methods Forty-eight Wistar rats were randomly divided into the intervention group, model group, and control group, with 16 rats in each. The OJ models were prepared in the intervention group and model group, and in the control group, only the common bile ducts of rats were isolated. At 24 h after modeling, the rats in the intervention group were orally administered APS normal saline solution ( 100 mglkg), and the control group and the model group with the same amount of normal saline, twice a day. Blood was taken from rats in each group at 14 days after modeling, and the serum diamine oxidase ( DAO) and intestinal fatty acid binding protein ( I-FABP) were detected by ELISA. After the blood was taken, the rats were sacrificed, and the small intestine tissues were taken. The proliferating cell nuclear antigen ( PCNA) protein was detected by Western blotting. The depth of glandular fossa and the height of villi were observed under an optical microscope. The terminal deoxynucleotidyl transferase dUTP nickel terminallabeling method (TUNEL) was used to count the number of apoptotic cells. IL-1β, IL-lRa, IL-10, TLR4 and NF-KB P65 positive cells were detected by immunofluorescence staining, and TLR4 and NF-KB P65 proteins were detected by Western blotting. Results Significant pathological damage occurred in the small intestine of rats in the model group. The levels of serum DAO, I-FABP, and TNF-α and IL-1β expression in the tissues were higher, while the tissue IL-l Ra, IL-10 levels were lower in the model group than in the control group (all P<0.05). The pathological damage of small intestine tissues became less in the intervention group; the levels of serum DAO, I-FABP, and TNF-α and IL-lβ expression in the tissues were lower, but the levels of IL-l Ra and IL-10 in the tissues were higher in the intervention group than in the model group (all P<0.05). Conclusions APS has a therapeutic effect on intestinal damage in OJ rats. It can protect the intestinal mucosal barrier of rats and resist small intestinal epithelial cell apoptosis by maintaining the anti-inflammatory and pro-inflammatory balance through the TLR4/NF -KB P65 pathway. [ABSTRACT FROM AUTHOR]

Objective To investigate the clinical features of patients with pancreatic neuroendocrine tumor (PNET) and the influencing factors for prognosis. Methods A retrospective analysis was performed for the clinical data of 54 patients with pathologically confirmed PNET in The First Affiliated People’s Hospital of Shanghai Jiao Tong University from March 2012 to April 2019, and clinical, pathological, and imaging features and prognosis were analyzed. The chi-square test or the Fisher’s exact test was used for comparison of categorical data between groups. The Kaplan-Meier method was used for survival analysis, and the log-rank test was used for comparison between groups. Results Among the 54 patients, there were 19 male patients (35.2%) and 35 female patients (64.8%). Of all patients, 47 (87.0%) had non-functional tumors and 7 (13.0%) had functional tumors. There were 17 patients (31.5%) with TNM stage I tumor, 26 patients (48.1%) with stage II tumor, 9 patients (16.7%) with stage III tumor, and 2 patients (3.7%) with stage IV tumor. According to the World Health Organization pathological grade, 24 patients (46.2%) had G1 tumor, 22 (42.3%) had G2 tumor, and 6 (11.5%) had G3 tumor. The patients with unclear boundary of tumor on CT (χ2=8.250, P=0.010) and MRI (χ2=6.048, P=0.031) tended to have higher postoperative recurrence rate and mortality rate. Overall survival time ranged from 1 to 86 months, with a 5-year survival rate of 92.0% and a disease-free survival time of 1-71 months. The univariate analysis showed that TNM stage (χ2=9.572, P=0.023), pathological grade (χ2=7.506, P=0.023), surgical margin invasion (χ2=15.123, P＜0.001), lymph node metastasis (χ2=4.716, P=0.030), and distant metastasis (χ2=5.534, P=0.019) were associated with overall survival time in the patients with PNET. Conclusion PNET patients with unclear tumor boundary on CT and MRI tend to have poor prognosis. TNM stage, pathological grade, surgical margin invasion, lymph node metastasis, and distant metastasis are closely associated with the prognosis of patients with PNET. [ABSTRACT FROM AUTHOR]

Nowadays, the parameter setting of the Spring Festival model mainly depends on subjective judgement for researchers. To solve the problem, firstly, the paper introduces factor-adjusted general process on Spring Festival and relevant details for model specification and model inspection. On this basis, the paper puts forward new ideas on selecting automatically Spring Festival model with optimal parameters based on "loop through" and sequential test method. Taking Spring Festival model's optimal effective phase length recognition of total retail sales of social consumer goods as an example, we examine its feasibility and validity. The empirical results show that the sequential test method based on seasonal peaks, outliers, Q statistics, AICC values, and BIC values can effectively identify the optimal infulence period length of the Spring Festival model, which can efficiently improve seasonal adjustment performance on Spring Festival model. [ABSTRACT FROM AUTHOR]

Karst rocky desertification(KRD)has become the most serious ecological disaster in Southwest China. It is very important and much-needed to explore the rule of spatial-temporal evolution of KRD for ecological restoration and sustainable development of the region. In this paper, the improved accurate remote sensing image interpreting method and CA-Markov prediction method were used to explore the spatial-temporal evolution rule of KRD in the study area from 1990 to 2021 based on the long time line remote sensing image of the year of 1990, 2004 and 2016. The results were as follows:the spatial -temporal evolution rule of KRD presented "first deterioration and then improvement" in the study area at nearly 30 years. The deterioration of KRD was affected by high intensity overload human activities and natural disasters in 1990-2004, which made the ecological environment deterioration. However, the KRD had gradually improved with the implementation of a series of governance projects, and a large number of rural labor forces were liberated from the land in 2004-2016, which made the natural environment restoration, and ecological system was getting better and better. At the same time, the trend of KRD evolution was showing improvement from the predicted years of 2016-2021 and the ecological environment in the region continued to become better. [ABSTRACT FROM AUTHOR]

Objective To explore the correlation between intestinal dose and acute radiation enteritis (ARE) in patients with cervical cancer received concurrent chemoradiotherapy, and optimize the dose limit of intestinal tissue. Methods 158 cervical cancer patients received concurrent chemoradiotherapy from 2014 to 2019 were selected in this study. According to CTCAE 5.0, patients with ARE ≥ grade 2 were classified as ARE ≥ grade 2 group, otherwise classified as ARE < grade 2 group. The intestinal dosimetric parameters of the two groups were recorded from the dose volume histogram. The correlation between ARE ≥ grade 2 and intestinal dosimetric parameters were analyzed using univariate and multivariate logistic regression. Results Among the 158 cervical cancer patients received concurrent chemoradiotherapy, 26 cases had grade 2 or above ARE (16.46%). The incidence of ARE ≥ grade 2 in patients with malnutrition and three-dimensional conformal radiotherapy was significantly higher than that in patients with well-nourished and intensity modulated radiotherapy (P < 0.05). The bowelbag V5, V40 and the rectal V50 of cervical cancer patients with ARE ≥ grade 2 were significantly higher than those with ARE < grade 2 (P < 0.05). ROC curves showed that bowelbag V5 and V40 were significant predictors of ARE ≥ grade 2 (AUC > 0.7, P < 0.05). Conclusions For patients with cervical cancer received concurrent chemoradiotherapy, the dose of bowelbag V5 and V40 should be considered to rationally optimize the dose of bowelbag in the radiotherapy plan, so as to reduce the incidence of ARE ≥ grade 2. [ABSTRACT FROM AUTHOR]

Objective Alpha-1-acid glycoprotein （ORM） was a new target for the development of weight loss drugs. To search for potential weight loss drugs that could target ORM from the compound library of already marketed drugs based on drug repurposing. Methods The pGL4.20-ORM1 promoter recombinant plasmid was contructed and validated, and then a lentiviral vector was utilized to establish stable AML12 cell lines expressing ORM1 promoter-LUC-PURO. This cell line was employed for high-throughput screening of compounds from the marketed drug library, and the luminescence value of the cells was characterized by enzyme marker. Results Primary screening and secondary screening of 1 470 compounds identified 42 compounds that increased ORM1 promoter expression and could be used for further weight loss effect assessment. Conclusion This study successfully constructed LV-AML12-ORM1 promoter-LUC-PURO stable expression cell lines using lentiviral vectors, laying a foundation for efficient and stable screening of weight loss drugs targeting ORM. [ABSTRACT FROM AUTHOR]

[Objective] Fresh bamboo shoots are bamboo shoot products that have not been blanched or pickled, with a crispy taste and refreshing flavor. However, fresh bamboo shoots breathe vigorously, which are prone to dehydration and wilting, making them difficult to keep fresh, thus affecting their sales. Spontaneous modified atmosphere packaging reduces the respiratory intensity of packaged fruits and vegetables by regulating the gas composition of the internal environment. Studying the effects of different modified atmosphere packaging treatments on the postharvest storage quality and lignification of fresh bamboo shoots could provide references for the selection of fresh-keeping packaging for fresh bamboo shoots. [Method] The peeled fresh bamboo shoots were packed in the spontaneous modified atmosphere preservation bag (thickness 20 μm, O2 transmission rate 11 643 cm³ /m² ·d·atm, water vapor transmission rate 62.586 g/m² ·d), and the vacuum bag made of nylon was used as control. The packaged fresh bamboo shoots were stored in the cold storage to study the quality change and the difference of lignification degree during storage. [Result] Compared with traditional vacuum preservation techniques, spontaneous modified atmosphere packaging could significantly reduce the respiratory intensity of fresh bamboo shoots during storage by creating a low oxygen and low carbon dioxide (O2 <5%, CO2 <5%) environment inside the bag through the respiration of the bamboo shoots themselves and the gas permeability of the membrane material. The peak intensity was only 46.93% of that of vacuum treatment. After 21 days of storage, modified atmosphere packaging significantly inhibited the browning and membrane lipid peroxidation of bamboo shoots. The brightness of the core of packaged bamboo shoots decreased by only 6.17% compared with that upon harvest, while that of vacuum packaging decreased by 17.74%. The content of malondialdehyde in vacuum packaged bamboo shoots was 2.93 times that in modified atmosphere packaging. In terms of lignification, the lignification rates of bamboo shoots in two types of packaging began to increase after 14 days of storage. The activities of key enzymes for lignification of bamboo shoots (phenylalanine ammonia lyase, peroxidase, cinnamon dehydrogenase) peaked in vacuum packaging, and lignification intensified; however, there was no peak in the related enzyme activity of bamboo shoots in the modified atmosphere packaging, and the enzyme activity increased slowly, delaying the lignification of bamboo shoot and maintaining the crisp taste of the bamboo shoots. After 21 days of storage, the lignin content of packaged bamboo shoots decreased by 15.01% compared to vacuum packaged bamboo shoots, effectively extending the freshness period of fresh bamboo shoots. [Conclusion] The low oxygen and low carbon dioxide gas environment in the spontaneous modified atmosphere packaging bag is conducive to the storage of fresh bamboo shoots, and the quality and nutrient content are significantly better than those of vacuum packaging treatment. It has a good market prospect for fresh bamboo shoots. [ABSTRACT FROM AUTHOR]

Antibacterial and mould-proof polyurethane coatings (PU-PHMG) were prepared via chemically bonding polyurethane (PU) with polyhexamethylene guanidine (PHMG). The molecular structure and performances of the products were characterized by Fourier Transform Infrared Spectroscopy (FT-IR), Abbe Refractometer and Atomic Force Microscope (AFM), etc. Properties of PU coatings affected by PHMG mass fraction was investigated. Results showed that when the mass fraction of PHMG was 1.01%, the bonding efficiency reached 93.59%, the inhibition rate against E.coli and S. aureus was above 99.5%. Then, the durabily antibacterial property of PU-PHMG was proved. Moreover, the antibacterial coating exhibited excellent performance of mould-proof and mechanical properties. [ABSTRACT FROM AUTHOR]

BACKGROUND: Recent experimental studies have found ultrasound mediated microbubbles potentiate stem cell therapy in myocardial infarction (MI)-induced heart failure, indicating a good application prospect. But whether ultrasound mediated nitric oxide (NO) microbubbles also have the same effect in the intracoronary transplantation of bone marrow mesenchymal stem cells (BMSCs) for treatment of large animals with MI is still unknown. OBJECTIVE: To investigate the effectiveness and possible mechanism of ultrasound mediated NO microbubbles in potentiating intracoronally transplanted BMSCs homing to the infarcted area in a MI pig model. METHODS: Density gradient centrifugation culture method was used in the isolation and cultivation of BMSCs. CM-Dil was used to label BMSCs in vitro. Twenty-four pigs were used to make MI models by blocking the left anterior descending coronary artery, and then were divided into PBS group, BMSCs group, ultrasound+microbubbles+BMSCs (MB) group, ultrasound+NO microbubbles+BMSCs (NO-MB) group(n=6 per group). In the PBS group, 10 mL of PBS was intracoronally injected. In the BMSCs group, about 1×107 BMSCs were diluted in 10 mL of PBS and then intracoronally infused. In the MB group, 0.1 mL/kg sulphur hexafluoride microbubbles (Sono Vue) was intracoronally injected together with ultrasound treatment (1 MHz, 2 W/cm2, 2 minutes), followed by intracoronary infusion of about 1×107 BMSCs that were diluted in 10 mL of PBS. In the NO-MB group, all methods and conditions were identical to those in the MB group except only 0.1 mL/kg of Sono Vue was replaced by 0.1 mL/kg NO microbubbles. Three pigs were sacrificed in each group 48 hours after CM-Dil positive BMSCs transplantation. The labeled BMSCs were observed and counted by fluorescent microscope after frozen sectioning of the infarct area. We assessed and compared left ventricular systolic function with M-mode ultrasound among groups at 4 weeks after intervention. After cardiac function test, the rest pigs were sacrificed and capillary density in the myocardial ischemic area was counted and compared after hematoxylin-eosin staining. RESULTS AND CONCLUSION: (1) The number of CM-Dil positive cells in the area of MI in the NO-MB group was much more than that in the MB group and BMSCs group with statistical significance (P < 0.05). (2) The left ventricle systolic function was significantly improved in the NO-MB group as compared with the MB group (P < 0.05). The same trend was observed between NO-MB group and BMSCs group as well as between NO-MB group and PBS group (P < 0.05). (3) The density of capillaries increased significantly in the NO-MB group compared with the MB group, BMSCs group and PBS group, respectively. To conclude, ultrasound mediated NO microbubble combined with intracoronary BMSCs transplantation can improve the left ventricular systolic function. The possible mechanism could be that ultrasound- mediated NO mocrobubbles promote the homing of transplanted BMSCs to the myocardial ischemia area as well as improve local angiogenesis. [ABSTRACT FROM AUTHOR]

In order to fill in the blank of training system of field bus teaching and IEC61131-3 language teaching in universities, a training system is developed. Processing instruments are monitored and processing parameters are controlled based on Foundation Fieldbus in this system, basic knowledge teaching of metrological verification can be achieved as well. Motor and light controls are simulated based on IEG61131-3 language. The interactive interface of PC program written by LabVIEW is friendly. The system has been used in practice teaching, and has achieved good teaching results. [ABSTRACT FROM AUTHOR]

In the process of ocean engineering construction, considering the rainfall is frequent at engineering field, there isn't enough long time to dry the coral sand, so the coral sand is half dry when used. Studying the performance of half-dry coral sand which under the natural conditions is very useful for mixing coral sand concrete, reducing construction cost and has high research significance and application value. The test results show that the coral sand early water absorption speed is very fast, 2 h water absorption rate reached 2.5 %, water absorption speed gradually slow down after 10 h, 48 h water absorption rate reached 6.4 %, water absorption rate has an obvious turning point at 8 h when water absorption rate is 5.3 % at 8 h, is 83 % of 48 h water absorption rate. Select feature water absorption rate 4 % to 6 % as additional water consumption, and determine the total water/cement ratio and pure water/cement ratio are reasonable, can reflect the reality of the coral sand concrete pure water/ cement ratio, pre-wetting can significantly improve the coral sand concrete working performance and mechanical properties. [ABSTRACT FROM AUTHOR]

Aiming at the development status of the amplifier for proportional valve and the control requirement of proportional directional valve, the control principle of digital amplifier for proportional directional valve(DAPDV) was analyzed and the system model of proportional directional valve was established. After the theoretical analysis, a DAPDV based on ARM7 micro-controller and the technology of the inverse-relief power driver circuit was implemented. With the aid of Visual C++ and ADS1.2 integrated development environment, the software system of the proportional amplifier was developed. The human-machine interface of host computer was designed, and the program control and close loop control of the proportional valve was realized. After determining the PID parameters of the proportional amplifier, the step response and sine wave signal response of the proportional directional valve system were tested on the electra-hydraulic proportional experiment rig. The results indicate that the system setting time for step response is short, the frequency response bandwidth is enough, and the designed proportional amplifier has good stability and dynamic performance. [ABSTRACT FROM AUTHOR]

Technical innovation represents an enterprise's core competitiveness. It's the source of power for sustainable development of the enterprise. The research, application and promotion of new technology, new material, new equipment and new process will improve a construction enterprise's productivity, core competitiveness on market and economic benefit. This article introduces the methods for patent development in construction engineering, such as enumerating of hope points, integrated innovation, and integration of technologies, with an aim to provide effective methods for construction enterprises to develop patents. [ABSTRACT FROM AUTHOR]

【Objective】The present paper aimed to study the effects of optimized fan frequency and different tobacco density on the temperature difference in the curing barn, changes in tobacco leaves and the quality of cured tobacco, and further determine the applicability of optimized fan frequency in the curing process. 【Method】Two factors of fan frequency and smoke density were set to track the changes of the three smoke density during the process of optimizing the fan frequency and the quality of the cured tobacco during the whole process, and conduct a comparative analysis in combination with the conventional full process of 50 Hz. 【Result】In terms of temperature difference in the roasting barn, as the baking progresses, the temperature difference basically followed the change rule of the main water loss stage>the late stage>the main yellowing stage>the preheating stage, and the optimization of the fan frequency reduces the temperature difference in the roasting barn. In terms of tobacco leaf changes, the unevenness of leaf temperature was D2Y>D1Y>D3Y>D2C; L* value and b* value first increase and then decrease, L* values of D2C and D1Y were always higher than that of D2Y and D3Y; a* value gradually increased with the change of the state, and there was no obvious difference between different treatments; The overall contraction of the optimized fan frequency was good, and the water loss form of D2Y tobacco was the best. In terms of quality of cured tobacco leaves, compared with D2C, D1Y, D2Y and D3Y had significant differences in appearance quality, chemical composition, sensory evaluation and comprehensive score (P<0.05), and D2Y had the highest score. 【Conclusion】Optimizing the fan frequency can have a lower temperature difference in the curing barn under different loading densities, better tobacco leaf changes and higher quality of cured tobacco, which has strong applicability. [ABSTRACT FROM AUTHOR]

The karst areas in southwest China are one of the key but difficult areas targeted in the “Beautiful China” construction initiative, which focuses on soil erosion, proportion of farmland, water pollution, karst drought, ecological restoration, carbon sink, ecological effects of urbanization, rocky desertification management indicators, and biodiversity and sustainability assessment. The study synthesizes the knowledge accumulated during ecological restoration practice in karst areas into 10 problems and solutions that are strong, universal and empirically supported. These problems and solutions help to explain the challenges of achieving sustainability in karst ecology restoration and thus point to solutions. They constitute a core set of principles that can guide scientists and governments in addressing sustainability challenges in karst ecological restoration project. [ABSTRACT FROM AUTHOR]

The relative spatial position between ultrasonic probe and pipe which is highly sensitive to the echo signal is one of the key factors affecting detection accuracy of the pipe wall thickness when detecting the pipe containing defect. A-scan ultrasonic internal detection experimental setup was self-developed to measure the echo signals under different relative spatial positions using Q235 carbon steel pipe with size of DN219×7.48 mm containing volumetric defect as tested sample. Echo signals of four relative positions between ultrasonic probe and pipe were analyzed, i.e., face-to-face standard state, axial dislocation state, circumferential dislocation state, axial and circumferential coexisting dislocation state. The time domain features of echo signals were analyzed. The transition method for calculating the pipe wall thickness was established based on the extracted time domain characteristic parameters, and finally the wall thickness was evaluated. It is found that the dislocation range covering the wall thickness of pipe with defects is smaller than that of pipe without defects. The influence of axial misalignment on echo characteristics of bottom surface is greater than circumferential misalignment. The results demonstrate that the wall thickness of pipe with defects can be predicted accurately by the proposed method with the maximum relative error less than 5% to measurements which meets the engineering accuracy. [ABSTRACT FROM AUTHOR]

On the basis of the lumped parameter method which simplifies the components in hydraulic system to nodes, a thermal resistance network model of clutch hydraulic system is proposed to investigate the effects of oil flow and rotation speed difference on the temperature rise of wet clutch during engaging. An experimental device is designed to validate the simulation results. The results show that the oil flow rate has a greater influence on the temperature rise of wet clutch under the condition of high heat flux than that under the condition of low heat flux. The oil flow brings a slight effect on the temperature rise when the cooling flow increases to the critical value. Both the relative speed and the pressure have an influence on heat flux. The temperature of wet clutch is a linear function of the relative speed of friction plates. The clutch temperature rises by 8.05 percent with every 100 r/min increment in the relative speed under same cooling condition. The proposed model is verified effectively by comparison of simulated results and experimental data, which can better reflect the thermal equilibrium of wet clutch hydraulic system in normal condition. [ABSTRACT FROM AUTHOR]

Aiming at the load imbalance of multiple controllers in software defined networks, this paper proposed a dynamic switches migration algorithm(DSMA). By modeling the controller-switch mapping as 0-1 programming problem, this algorithm used the immune particle swarm algorithm to achieve the load balance of the controllers and ensured the transmission delay between controllers and switches at the same time. Simulation results show that, compared with the existed typical algorithms such as nearest migration algorithm and lowest utilization migration algorithm, DSMA achieves good load balancing of controllers, reduces the response time of the PACKET_IN messages, improves the system response speed and increases the weighted comprehensive evaluation meanly to 25.3%. [ABSTRACT FROM AUTHOR]

Objective To explore the expression changes of the transcription factor Twist and the E-cadherin in the o-ral squamous cell carcinoma (OSCC) tissues and to investigate the clinical significance. Methods The immunohisto-chemical SP method was used to detect the expression levels of the Twist and E-cadherin in 65 cases of OSCC tissues and 45 cases of oral normal mucosa tissues. In addition, the relationship between the expression of Twist/E-cadherin and the clinicpathologic characteristics was analyzed. and the Spearman was used to explore the correlation between the Twist and E-cadherin in OSCC tissues. Results The positive expression rates of Twist in the OSCC tissues and oral normal mucosa tissues were 72.31% (47/65) and 11.11% ( 5/45 ) , respectively (P < 0. 05 ). The positive expression rates of E-cadherin in the OSCC tissues and oral normal mucosa tissues were 23. 08% ( 19/65 ) and 86. 67% (39/45 ) , respectively ( P < 0. 05). The Twist and E-cadherin expression levels in the OSCC tissues were related with the lymph node metastasis and the clinical stages ( both P <0. 05 ) , but were not related with the gender, age. differentiation degree and the type ( all P > 0. 05 ). The expression of Twist and E-cadherin was negatively correlated in the OSCC tissues (r = - 0. 412 , P < 0. 05 ). Conclusions The transcription factor Twist is up-regulated and E-cadherin is down-regulated, both of them play a critical role in the occurrence and malignant progression of OSCC. [ABSTRACT FROM AUTHOR]

部分前列腺癌患者在初诊时已经发现转移，预后较差。转移性激素敏感性前列腺癌 (mHSPC) 是转移性 前列腺癌中较常见的一种类型。分析mHSPC预后相关因素并建立预后评估模型，可为指导新药和最佳治疗方案选 择提供依据. mHSPC 常见预后相关因素包括：前列腺特异性抗原，其水平降低时间、速度、数值等都与mHSPC的预 后关系密切; Gleason评分，其值越高患者预后越差；转移灶（骨转移、内脏转移), 高危险/高负荷的肿瘤患者比低危 险/低负荷预后差; 碱性磷酸酶, 可能是骨转移性肿瘤的重要指标，是雄激素剥夺治疗后mHSPC患者死亡的风险预 测指标；乳酸脱氢酶，在肿瘤代谢, 增殖, 侵袭和转移中起至关重要的作用；年龄也是影响预后的重要因素. [ABSTRACT FROM AUTHOR]

The front silver paste is the key material for the metallization of crystalline solar cells. The PbO component in glass plays an important role in achieving good ohmic contact between silver paste and silicon wafer. The characteristics of Pb-free glass and Pb glass are characterized by TGA-DSC and SEM. The results show that the glass containing PbO has low transition temperature, high heat release, strong ability to dissolve Ag. The number of silver particles precipitated during cooling is more, the particle size is small, the arrangement is regular and the distribution is uniform. Therefore, it has good ohmic contact. The influence of glass with different PbO content on the electrical properties of silicon wafers with different square resistance is studied. The results show that with the increase of silicon square resistance, the increase of PbO content in glass helps to improve the ohmic contact with the silicon junction emitter. But when the PbO content is too high, the dissolved Ag content is too large, and the glass etches the silicon emitter deeply, resulting in serious damage to P-N junction, large leakage, and significant decrease in Voc. When the PbO content is 15 wt%-25 wt%, it has good ohmic contact and little effect on Voc, so it has better efficiency of silicon solar cells. [ABSTRACT FROM AUTHOR]

Objective: To explore the molecular mechanism of prostate cancer bone metastasis by bioinformatics, and to provide a new target for prevention and treatment of prostate cancer bone metastasis. Methods: The dataset GSE74685 containing 20 cases of prostate cancer bone metastasis and 69 cases of prostate cancer lymph node metastasis were retrieved and screened from the Gene Expression Database （GEO）. The Limma package of R software is used to preprocess the original data and screen differentially expressed genes （DEGs）. DEGs were analyzed by GO function enrichment and KEGG pathway enrichment analysis through the gene function annotation online tool DAVID. The protein-protein interaction （PPI） network of DEGs was constructed by using the STRING online retrieval tool and Cytoscape software. And the important modules and key genes were screened by using MCODE and cytoHubba plug-ins. The expression, prognosis and diagnostic value of key genes were verified by HCMDB and GEPIA database. Results: A total of 2 022 DEGs were selected from the dataset GSE74685, including 842 up-regulated genes and 1 180 down-regulated genes. GO functional enrichment analysis showed that DEGs were mainly enriched in the extracellular matrix organization, collagen catabolic process, response to mechanical stimulus, and positive regulation of neutrophil chemotaxis. KEGG pathway enrichment suggested that focal adhesion and ECM-receptor interaction were the main signal pathway for DEGs enrichment. Eleven key genes, EZH2, PLG, SRC, CAV1, CHD4, HIST2H2BE, KDM1A, POLR2E, VWF, APOE and THBS1 were obtained through PPI network screening. The verification of gene expression and survival analysis of 11 key genes showed that APOE and EZH2 were closely related to prostate cancer bone metastasis. Conclusion: EZH2 and APOE may be involved in the occurrence and development of prostate cancer bone metastasis, which can be used as potential therapeutic targets and provide a new research direction for the prevention and treatment of prostate cancer bone metastasis. [ABSTRACT FROM AUTHOR]

目的探讨面颈部皮肤结核患者临床诊治情况，分析该病的临床特点，提高治疗效率。方法选取该院 2013年11月至2016年12月收治的48例面颈部皮肤结核患者作为研究对象，分析其临床表现及诊治情况。结果不 同类型的皮肤结核病的临床表现不同。本组48例患者误诊率达47.92%(23/48)，经四联抗结核药物治疗后治愈率为 67.67%(32/48)。结论皮肤结核病的临床表现与患者免疫力及结核杆菌入侵途径、毒性、菌量等有关，且复杂多样，确诊 后应尽早进行抗结核药物治疗，整体预后良好。 [ABSTRACT FROM AUTHOR]

目的观察后路短节段椎弓根螺钉固定联合伤椎置钉治疗胸腰椎爆裂性骨折患者的临床疗效。方法将60例胸腰椎爆裂性骨折患者随机分为观察组和对照组30例,均行后路短节段椎弓根螺钉固定治疗,观察组另行伤椎置钉。记录手术时间、出血量及术后住院时间、术后并发症发生情况,术后第6个月行Oswestry功能障碍指数评价,采用脊柱X线片、CT测定患者术前、术后即刻及术后第6个月伤椎前缘高度、Cobb角。结果两组手术时间、出血量、术后住院时间、术后并发症发生率、术后伤椎高度矫正率、术后Cobb角矫正率、术后6个月Oswestry功能障碍指数比较差异无统计学意义。观察组术后6个月伤椎高度矫正丢失率及Cobb角矫正丢失率均低于对照组(P均<0.05)。结论后路短节段椎弓螺钉固定联合伤椎置钉有利于恢复及保持胸腰椎爆裂性骨折患者的椎体高度,减少伤椎高度矫正丢失。 [ABSTRACT FROM AUTHOR]

Objective To investigate the reverse effect of microR (miR)-7 on adriamycin resistance of breast cancer cells and its downstream molecule mechanism. Methods Human breast cancer MCF-7 cell line was exposed to gradually increasing density of adriamycin (ADR) that was used to establish ADR-resistant MCF-7 / ADR cell line. MCF-7 or MCF-7 / ADR cells were transfected with miR-7 mimic or miR-7 inhibitor for 48 h. Then cells were exposed to ADR (100 ng /m L) for 24 h. MTT assay was used to evaluate cell survival, fluorescent quantitative PCR was used to determine miR-7 and ABCC10 mRNA expression and immunoblotting was used to determine ABCC10 protein expression. Results MCF-7 / ADR cell expressed lower level of miR-7 and high level of ABCC10. MiR-7 overexpression in MCF-7 / ADR cell inhibited ABCC10 mRNA and protein expression and enhanced ADR resistance thereby leading to the reduction of cell viability. In the contrary, silencing miR-7 in MCF-7 promoted ABCC10 mRNA and protein expression and increased cell viability. Conclusion Regulating MiR-7 expression may reverse the ADR resistance of breast cancer cells and its mechanism may be that miR-7 reverses ADR resistance by regulating ABCC10 expression. [ABSTRACT FROM AUTHOR]

Objective To evaluate the influence of position deviation of high definition multi leaf collimator (HDMLC) on the dose distribution under different dose rates in the intensity modulated radiotherapy (IMRT) of prostate cancer. Methods 32 pa-tients with prostate cancer from February 2014 to April 2015 were selected and performed the radiotherapy by using the IMRT plan-ning with 9 irradiation fields, the irradiation interval of 40°,Varian Truebeam accelerator HDMLC, Eclipse treatment planning sys-tem, the MLC position deviation of introduced fixed numerical values (0.3,0.5,1.0,2.0 mm) for each planning was under the follow-ing conditions:(1)simultaneous enlargement of MLC X1 and X2 directions;(2)simultaneous shrink of MLC X1 and X2 directions. The two indexes were used for the comparison of each planning results:(1)the 95%isodose line conformal index(95%CI);(2) the rectum maximum dose(rectum Dmax). Results (1) If MLC amplified deviation at the MLC X1X2 collimator directions≥0.3 mm, 95%CI was decreased, while rectum Dmax was increased, moreover this influence was directly proportional to the enlargement of dose rate and deviation amount;(2)if the MLC shrunk deviation at the MLC X1X2 collimator directions≥0.3 mm, 95%CI was firstly increased to the peak value;if MLC shrunk deviation≥1.0 mm, 95%CI was rapidly dropped, moreover the higher the dose, the more obvious the drop;however, rectum Dmax showed a obviously decreasing trend and this reduce was directly proportional to the dose rate and deviation amount. Conclusion If the leaf deviation of HDMLC is more than 0.3 mm, a large number of dose deviation could occur in the IMRT planning of prostate cancer, moreover this deviation could be more obvious with the increase of dose rate, therefore the MLC daily quality assurance should control the average MLC position deviation within 0.3 mm. [ABSTRACT FROM AUTHOR]

Street vendors are an indispensable part of the urban social ecosystem, but due to a lack of comprehensive understanding, many cities have adopted simple eviction policies, resulting in the gradual marginalization and stigmatization of the street economy. The efficient governance of street vendors requires the comprehensive investigation of their business scale and spatial distribution information. However, traditional methods have limitations in terms of automatically surveying large-scale street vendor information, particularly spatial distribution. This paper proposes a method for the automatic investigation spatial distribution of street vendors based on street-view images and a deep-learning object recognition model. Street-view images were collected at fixed intervals according to the urban road network, and 1, 957 images containing one or more vendors were selected through human-machine interaction to establish street vendor label data. To achieve high recognition model accuracy, the category labels were subdivided into four categories: ground stalls, table stalls, tricycle stalls, and small truck stalls, based on the goods carriers used by street vendors. A deep neural-networkbased image object detection model based on YOLO v4 was constructed to identify street vendors in the streetview image library, with an average F1 value of 0.77 and an mAP of 0.67. The accuracy of the model was satisfactory for investigating the number and location of street vendors covering the main roads in the city and then applying a kernel density distribution model to evaluate the spatial distribution pattern of street vendors. Using street vendors in Guangzhou as a case study, the proposed automatic investigation model identified 26,119 street vendors from 3,339,062 street-view images. The results showed that the street vendors were distributed in a multicenter aggregation pattern in the central urban area, mainly concentrated in areas with high pedestrian traffic, such as subway stations and urban villages; their numbers increased as road grades decreases. Street vendors were mainly distributed in areas with medium rents. The proposed method is helpful for performing the efficient, low-cost, and city-scale mapping of street vendors; the results obtained provide suggestions for formulating and implementing spatial governance policies for the informal economy and further provide suggestions for improving and implementing spatial governance policies for open and diverse urban street-view images. The results can be used as a reference for the location preference analysis of practitioners, the exploration of NIMBY syndrome, and the determination of the formalization zone. Although street-view images have an insufficient spatiotemporal coverage, using them to perform street vendor investigations is a low-cost and efficient method compared with the use of traditional investigation methods and data sources. In addition, the method proposed in this article can be coupled with multitask deep learning algorithms to investigate additional dimensions of street vendor information, such as the sex, age, and type of business of street vendors. Relevant research needs to be conducted in the future. [ABSTRACT FROM AUTHOR]

Aiming at the problem of insufficient fault diagnosis accuracy during the operation of the elevator system and the new method of elevator car vibration fault diagnosis in the application of convolutional neural networks, the elevator carrier quality tester was used to collect a large number of vibration signals during the operation of the elevator, then the vibration signals was separated and filtered. A continuous wavelet was used to perform time-frequency transformation on the preprocessed signal, and the transformed RGB image was made the inputted of deep learning model. The application of depth in elevator car vibration fault diagnosis was analyzed. The overall plan of elevator car vibration fault diagnosis was designed and the deep learning plan was implemented through PyTorch. The convolutional neural network was applied to the elevator car vibration fault diagnosis. The deep residual neural network classifier was analyzed and trained through supervised learning and was compared with traditional machine learning methods. The results indicate that the accuracy of the deep learning fault diagnos is scheme is 3% higher than that of the traditional machine learning fault diagnosis method. The deep learning solution can effectively diagnose elevator faults and open up a new path for elevator fault diagnosis. [ABSTRACT FROM AUTHOR]

目的探讨应用集束化护理方案对神经外科气管切开患者肺部感染预防的临床效果。方法选取 2015 年1 月至2016 年12 月该院神经外科收治的100 例颅脑损伤需行气管切开术患者，根据随机原则将其分为对照 组和观察组，每组50 例。对照组患者实施该院神经外科常规的基础方案护理，观察组患者应用集束化护理方案进行护 理干预。观察、比较2 组患者护理干预后肺部感染及并发症发生情况，患者气管切开时间、入住重症监护病房（ICU）时 间及住院总费用等，以及患者和家属对临床护理的满意度。结果观察组患者肺部感染发生率及并发症发生率均明显 低于对照组，患者气管切开时间、入住ICU 时间及住院总费用均明显优于对照组，患者及家属对临床护理的总满意度 明显高于对照组，差异均有统计学意义（P<0.05）。结论对神经外科气管切开患者应用集束化护理方案进行护理干 预，能有效降低患者肺部感染发生率及并发症发生率，缩短患者气管切开时间、入住ICU 时间，明显降低患者住院治疗 总费用，提高患者及家属对临床护理的满意度，其临床应用的综合效果显著，值得进一步推广使用。 [ABSTRACT FROM AUTHOR]

[Objectives] In this study, a method of detecting the external quality on freeze-dried strawberry based on binocular stereo vision was developed, in order to realize the nondestructive testing and grading of freeze-dried strawberry. [Methods]The binocular stereo vision technology was used to obtain the parallax data of each pixel in the freeze-dried strawberry image through the pixel matching algorithm, its three-dimensional model was established, and the volume of the model, color, shape and texture quality indexes of the image were calculated as the characteristic parameters. Then the successive projections algorithm (SPA)was used to screen the optimal characteristic parameters, and the external quality grade recognition model of freeze-dried strawberry was established with the unfiltered and filtered characteristic parameters respectively. In addition, the discrimination and grading effects of each model were compared. Finally, the optimal recognition model was selected to develop the external quality grading software of freeze-dried strawberry and verified. [Results]The total classification accuracy of the support vector machines (SVM) and the partial least squares discriminant analysis (PLS-DA) prediction models was 91.7% and 86.7%, respectively. The total classification accuracy of SVM model and PLS-DA model based on the feature parameters (volume and red component meanfiltered by SPA algorithm was 95.0% and 81.7% respectively. Finally, the external quality recognition software of freeze-dried strawberry was developed by using the SVM model constructed by the characteristic parameters screened by SPA algorithm, with the total accuracy of 90.8%. [Conclusions]The SVM hierarchical prediction model based on the feature parameters filtered by SPA had the better prediction effect, and the total accuracy of modeling set and prediction set were 97.8% and 95.0% respectively. In addition, the software developed based on the aforementioned model could realize the detection of the external quality of freeze-dried strawberry. [ABSTRACT FROM AUTHOR]

To investigate the effect of hepatectomy for hepatic echinococcosis and its influence on prognosis and liver function. 103 patients with hepatic hydatidosis who were admitted to our hospital from February 2015 to May 2018 were selected as the research objects. All patients were divided into group A (n=51, complete extracapsular extraction) and group B (n=52, hepatectomy) according to different surgical methods. The perioperative clinical indicators, liver function indicators and complications were compared between the two groups. During the follow-up period of half a year, the death and in situ recurrence of the two groups were recorded. The amount of intraoperative bleeding in group B was less than that in group A. The operation time, extubation time after operation and hospitalization time were shorter than those in group A. There was significant difference between the two groups (P<0.05). Compared with pre-operation, the glutamic-alanine aminotransferase, bilirubin and glutamic-oxaloacetic aminotransferase increased in two groups at 3 days after operation and 7 days after operation, but group B was lower than group A (P<0.05). Compared with pre-operation, the albumin in group B was lower than that in group A at 3 days and 7 days after operation, but group B was higher than group A (P<0.05). Compared with 3 days after operation, the glutamic-alanine aminotransferase, bilirubin and glutamic-oxaloacetic aminotransferase decreased and albumin increased in two groups at 7 days after operation (P<0.05). The total incidence of postoperative complications in group B was 7.69% (4/52), which was significantly lower than that in group A 23.52% (12/51), there was significant difference between groups(P<0.05). There was no patient died during the follow-up period in both groups, there was no significant difference in the recurrence rate in situ between the two groups (P>0.05). Hepatectomy is safe and effective in the treatment of hepatic echinococcosis. It can reduce the amount of bleeding during operation, promote the recovery of patients after operation, and reduce the effect of operation on liver function, the recurrence rate is low and the prognosis of patients is good. [ABSTRACT FROM AUTHOR]

On the basis of searching a large number of literatures, this paper systematically classifies ambient temperaes asphalt mixes from the aspects of material composition and strength formation mechanism; the influencing factors and research progress of various ambient temperature asphalt mixes are introduced; finally, comprehensively compare the performance and characteristics of various ambient temperature asphalt mixes, and put forward prospects for the next research, in order to provide help for engineers to reasonably design ambient temperature asphalt mixes and promote the innovative development of green roads. [ABSTRACT FROM AUTHOR]