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1,141 results on '"Bruce M. Psaty"'

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1. Proteomics of left ventricular structure in the Multi‐Ethnic Study of Atherosclerosis

2. Immune cell profiling of the ICAM1 p.K56M heart failure with preserved ejection fraction risk variant

3. Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height

4. Rare variant contribution to the heritability of coronary artery disease

5. Assessment of Inflammatory Biomarkers and Incident Atrial Fibrillation in Older Adults

6. Determinants of mosaic chromosomal alteration fitness

7. Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores

8. A polygenic risk score of atrial fibrillation improves prediction of lifetime risk for heart failure

9. Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance

10. X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

11. Proteomics for heart failure risk stratification: a systematic review

12. Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

13. Identification of circulating proteins associated with general cognitive function among middle-aged and older adults

14. Investigating peripheral blood monocyte and T-cell subsets as non-invasive biomarkers for asymptomatic hepatic steatosis: results from the Multi-Ethnic Study of Atherosclerosis

15. Genetic insights into resting heart rate and its role in cardiovascular disease

16. Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups

17. Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program

18. Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

19. Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program

20. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

21. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

22. Association Between Whole Blood–Derived Mitochondrial DNA Copy Number, Low‐Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk

23. Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization [version 1; peer review: 2 approved]

24. Whole genome sequence analysis of blood lipid levels in >66,000 individuals

25. A population‐based meta‐analysis of circulating GFAP for cognition and dementia risk

26. Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease

27. Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

28. Plasma Trimethylamine‐N‐Oxide and Incident Ischemic Stroke: The Cardiovascular Health Study and the Multi‐Ethnic Study of Atherosclerosis

29. Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations

30. Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes

31. Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program

32. A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood

33. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

34. DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases

35. Plasma sphingolipids, lung function and COPD: the Cardiovascular Health Study

36. Rare coding variants in RCN3 are associated with blood pressure

37. Association of low-frequency and rare coding variants with information processing speed

38. Meta-analyses identify DNA methylation associated with kidney function and damage

39. Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

40. The genomics of heart failure: design and rationale of the HERMES consortium

41. Circulating differentiated and senescent lymphocyte subsets and incident diabetes risk in older adults: The Cardiovascular Health Study

42. Inflammation and Incident Conduction Disease

43. Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function

44. Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study

45. Plasma epoxyeicosatrienoic acids and diabetes-related cardiovascular disease: The cardiovascular health study

46. Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

47. A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

48. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

49. Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

50. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

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